{"id":"https://openalex.org/W3083335094","doi":"https://doi.org/10.1158/1538-7445.am2020-lb-184","title":"Abstract LB-184: A lncRNA-histone acetyltransferase complex induces colorectal oncogenesis through regulation of a metabolic kinase network","display_name":"Abstract LB-184: A lncRNA-histone acetyltransferase complex induces colorectal oncogenesis through regulation of a metabolic kinase network","publication_year":2020,"publication_date":"2020-08-15","ids":{"openalex":"https://openalex.org/W3083335094","doi":"https://doi.org/10.1158/1538-7445.am2020-lb-184","mag":"3083335094"},"language":"en","primary_location":{"id":"doi:10.1158/1538-7445.am2020-lb-184","doi":"https://doi.org/10.1158/1538-7445.am2020-lb-184","is_oa":false,"landing_page_url":"https://doi.org/10.1158/1538-7445.am2020-lb-184","pdf_url":null,"source":{"id":"https://openalex.org/S168522863","display_name":"Cancer Research","issn_l":"0008-5472","issn":["0008-5472","1538-7445"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320273","host_organization_name":"American Association for Cancer Research","host_organization_lineage":["https://openalex.org/P4310320273"],"host_organization_lineage_names":["American Association for Cancer Research"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer Research","raw_type":"journal-article"},"volume":null,"type":"conference-abstract","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5026535780","display_name":"Christos Polytarchou","orcid":"https://orcid.org/0000-0002-1948-7934","observed_orcids":["https://orcid.org/0000-0002-1948-7934"]},"institutions":[{"id":"https://openalex.org/I52590639","display_name":"Nottingham Trent University","ror":"https://ror.org/04xyxjd90","country_code":"GB","type":"education","lineage":["https://openalex.org/I52590639"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Christos Polytarchou","raw_affiliation_strings":["1Nottingham Trent University, Nottingham, United Kingdom;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1Nottingham Trent University, Nottingham, United Kingdom;","institution_ids":["https://openalex.org/I52590639"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049770365","display_name":"Maria Hatziapostolou","orcid":"https://orcid.org/0000-0003-2493-7028","observed_orcids":["https://orcid.org/0000-0003-2493-7028"]},"institutions":[{"id":"https://openalex.org/I52590639","display_name":"Nottingham Trent University","ror":"https://ror.org/04xyxjd90","country_code":"GB","type":"education","lineage":["https://openalex.org/I52590639"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Maria Hatziapostolou","raw_affiliation_strings":["1Nottingham Trent University, Nottingham, United Kingdom;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1Nottingham Trent University, Nottingham, United Kingdom;","institution_ids":["https://openalex.org/I52590639"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069224672","display_name":"\u039c\u03b1\u03c1\u03af\u03bd\u03b1 \u039a\u03bf\u03c5\u03c4\u03c3\u03b9\u03bf\u03cd\u03bc\u03c0\u03b1","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I161318765","display_name":"University of California, Los Angeles","ror":"https://ror.org/046rm7j60","country_code":"US","type":"education","lineage":["https://openalex.org/I161318765"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Marina Koutsioumpa","raw_affiliation_strings":["2University of California Los Angeles, Los Angeles, CA;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"2University of California Los Angeles, Los Angeles, CA;","institution_ids":["https://openalex.org/I161318765"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038504302","display_name":"Niki Christodoulou","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I52590639","display_name":"Nottingham Trent University","ror":"https://ror.org/04xyxjd90","country_code":"GB","type":"education","lineage":["https://openalex.org/I52590639"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Niki Christodoulou","raw_affiliation_strings":["1Nottingham Trent University, Nottingham, United Kingdom;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1Nottingham Trent University, Nottingham, United Kingdom;","institution_ids":["https://openalex.org/I52590639"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012053345","display_name":"Tung On Yau","orcid":"https://orcid.org/0000-0002-3283-0370","observed_orcids":["https://orcid.org/0000-0002-3283-0370"]},"institutions":[{"id":"https://openalex.org/I52590639","display_name":"Nottingham Trent University","ror":"https://ror.org/04xyxjd90","country_code":"GB","type":"education","lineage":["https://openalex.org/I52590639"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Tung On Yau","raw_affiliation_strings":["1Nottingham Trent University, Nottingham, United Kingdom;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1Nottingham Trent University, Nottingham, United Kingdom;","institution_ids":["https://openalex.org/I52590639"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025682682","display_name":"Eleni Birli","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I52590639","display_name":"Nottingham Trent University","ror":"https://ror.org/04xyxjd90","country_code":"GB","type":"education","lineage":["https://openalex.org/I52590639"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Eleni Birli","raw_affiliation_strings":["1Nottingham Trent University, Nottingham, United Kingdom;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1Nottingham Trent University, Nottingham, United Kingdom;","institution_ids":["https://openalex.org/I52590639"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076484760","display_name":"Odette Pomenya","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I52590639","display_name":"Nottingham Trent University","ror":"https://ror.org/04xyxjd90","country_code":"GB","type":"education","lineage":["https://openalex.org/I52590639"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Odette Pomenya","raw_affiliation_strings":["1Nottingham Trent University, Nottingham, United Kingdom;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1Nottingham Trent University, Nottingham, United Kingdom;","institution_ids":["https://openalex.org/I52590639"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078139870","display_name":"Cristina Montiel\u2010Duarte","orcid":"https://orcid.org/0000-0002-9144-8809","observed_orcids":["https://orcid.org/0000-0002-9144-8809"]},"institutions":[{"id":"https://openalex.org/I52590639","display_name":"Nottingham Trent University","ror":"https://ror.org/04xyxjd90","country_code":"GB","type":"education","lineage":["https://openalex.org/I52590639"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Cristina Montiel-Duarte","raw_affiliation_strings":["1Nottingham Trent University, Nottingham, United Kingdom;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1Nottingham Trent University, Nottingham, United Kingdom;","institution_ids":["https://openalex.org/I52590639"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022463966","display_name":"Swapna Mahurkar Joshi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I161318765","display_name":"University of California, Los Angeles","ror":"https://ror.org/046rm7j60","country_code":"US","type":"education","lineage":["https://openalex.org/I161318765"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Swapna Mahurkar Joshi","raw_affiliation_strings":["2University of California Los Angeles, Los Angeles, CA;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"2University of California Los Angeles, Los Angeles, CA;","institution_ids":["https://openalex.org/I161318765"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087437075","display_name":"Dani\u00ebl W. Hommes","orcid":"https://orcid.org/0000-0002-1559-1179","observed_orcids":["https://orcid.org/0000-0002-1559-1179","https://orcid.org/0000-0001-6410-1386"]},"institutions":[{"id":"https://openalex.org/I2800006345","display_name":"Leiden University Medical Center","ror":"https://ror.org/05xvt9f17","country_code":"NL","type":"funder","lineage":["https://openalex.org/I2800006345"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Daniel W. Hommes","raw_affiliation_strings":["3Leiden University Medical Center, Leiden, Netherlands;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"3Leiden University Medical Center, Leiden, Netherlands;","institution_ids":["https://openalex.org/I2800006345"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108216974","display_name":"Hein W. Verspaget","orcid":"https://orcid.org/0000-0001-5769-6887","observed_orcids":["https://orcid.org/0000-0001-5769-6887"]},"institutions":[{"id":"https://openalex.org/I2800006345","display_name":"Leiden University Medical Center","ror":"https://ror.org/05xvt9f17","country_code":"NL","type":"funder","lineage":["https://openalex.org/I2800006345"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Hein W. Verspaget","raw_affiliation_strings":["3Leiden University Medical Center, Leiden, Netherlands;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"3Leiden University Medical Center, Leiden, Netherlands;","institution_ids":["https://openalex.org/I2800006345"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100614702","display_name":"Jun Qing Yu","orcid":"https://orcid.org/0000-0001-5008-2153","observed_orcids":["https://orcid.org/0000-0001-5008-2153"]},"institutions":[{"id":"https://openalex.org/I177725633","display_name":"Chinese University of Hong Kong","ror":"https://ror.org/00t33hh48","country_code":"HK","type":"education","lineage":["https://openalex.org/I177725633"]}],"countries":["HK"],"is_corresponding":false,"raw_author_name":"Jun Yu","raw_affiliation_strings":["4Li Ka Shing Institute of Health Sciences, Chinese University of Hong Kong, Hong Kong, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"4Li Ka Shing Institute of Health Sciences, Chinese University of Hong Kong, Hong Kong, China","institution_ids":["https://openalex.org/I177725633"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5101843028","display_name":"Dimitrios Iliopoulos","orcid":"https://orcid.org/0000-0002-6832-0786","observed_orcids":["https://orcid.org/0000-0002-6832-0786"]},"institutions":[{"id":"https://openalex.org/I161318765","display_name":"University of California, Los Angeles","ror":"https://ror.org/046rm7j60","country_code":"US","type":"education","lineage":["https://openalex.org/I161318765"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Dimitrios Iliopoulos","raw_affiliation_strings":["2University of California Los Angeles, Los Angeles, CA;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"2University of California Los Angeles, Los Angeles, CA;","institution_ids":["https://openalex.org/I161318765"]}]}],"institutions":[],"countries_distinct_count":4,"institutions_distinct_count":4,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"80","issue":"16_Supplement","first_page":"LB","last_page":"184"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10515","display_name":"Cancer-related molecular mechanisms research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10515","display_name":"Cancer-related molecular mechanisms research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11482","display_name":"RNA modifications and cancer","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10269","display_name":"Epigenetics and DNA Methylation","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hotair","display_name":"HOTAIR","score":0.9940000176429749},{"id":"https://openalex.org/keywords/long-non-coding-rna","display_name":"long non-coding RNA","score":0.968999981880188},{"id":"https://openalex.org/keywords/pcaf","display_name":"PCAF","score":0.9449999928474426},{"id":"https://openalex.org/keywords/kat2b","display_name":"KAT2B","score":0.9629999995231628},{"id":"https://openalex.org/keywords/histone-acetylation","display_name":"histone acetylation","score":0.9380000233650208},{"id":"https://openalex.org/keywords/h3k27-acetylation","display_name":"H3K27 acetylation","score":0.949999988079071},{"id":"https://openalex.org/keywords/colorectal-cancer","display_name":"colorectal cancer","score":0.9459999799728394},{"id":"https://openalex.org/keywords/metabolic-reprogramming","display_name":"metabolic reprogramming","score":0.7559999823570251},{"id":"https://openalex.org/keywords/pi3k-akt-signaling","display_name":"PI3K/Akt signaling","score":0.8730000257492065},{"id":"https://openalex.org/keywords/mek-signaling","display_name":"MEK signaling","score":0.8669999837875366},{"id":"https://openalex.org/keywords/cancer-epigenetics","display_name":"cancer epigenetics","score":0.7829999923706055},{"id":"https://openalex.org/keywords/patient-survival","display_name":"patient survival","score":0.6710000038146973}],"concepts":[{"id":"https://openalex.org/C107793267","wikidata":"https://www.wikidata.org/wiki/Q14908260","display_name":"PCAF","level":4,"score":0.9508317112922668},{"id":"https://openalex.org/C2781128886","wikidata":"https://www.wikidata.org/wiki/Q18062498","display_name":"HOTAIR","level":5,"score":0.8900079727172852},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.6476162672042847},{"id":"https://openalex.org/C2778001298","wikidata":"https://www.wikidata.org/wiki/Q1036906","display_name":"Histone acetyltransferase","level":4,"score":0.5488076210021973},{"id":"https://openalex.org/C86554907","wikidata":"https://www.wikidata.org/wiki/Q285613","display_name":"PI3K/AKT/mTOR pathway","level":3,"score":0.4970720112323761},{"id":"https://openalex.org/C64927066","wikidata":"https://www.wikidata.org/wiki/Q36293","display_name":"Histone","level":3,"score":0.49387413263320923},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.491553395986557},{"id":"https://openalex.org/C2780914512","wikidata":"https://www.wikidata.org/wiki/Q25323943","display_name":"H3K4me3","level":5,"score":0.48905810713768005},{"id":"https://openalex.org/C555283112","wikidata":"https://www.wikidata.org/wiki/Q1637543","display_name":"Carcinogenesis","level":3,"score":0.4559299945831299},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.45589354634284973},{"id":"https://openalex.org/C75217442","wikidata":"https://www.wikidata.org/wiki/Q423650","display_name":"Protein kinase B","level":3,"score":0.4229554235935211},{"id":"https://openalex.org/C2911110750","wikidata":"https://www.wikidata.org/wiki/Q7117884","display_name":"P300-CBP Transcription Factors","level":5,"score":0.41676998138427734},{"id":"https://openalex.org/C62203573","wikidata":"https://www.wikidata.org/wiki/Q15087973","display_name":"Long non-coding RNA","level":4,"score":0.2955610156059265},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.25109100341796875},{"id":"https://openalex.org/C2910921701","wikidata":"https://www.wikidata.org/wiki/Q1036906","display_name":"Histone Acetyltransferases","level":4,"score":0.21826475858688354},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.21056857705116272},{"id":"https://openalex.org/C62478195","wikidata":"https://www.wikidata.org/wiki/Q828130","display_name":"Signal transduction","level":2,"score":0.19269004464149475},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.18596839904785156},{"id":"https://openalex.org/C127561419","wikidata":"https://www.wikidata.org/wiki/Q224527","display_name":"Downregulation and upregulation","level":3,"score":0.16296404600143433},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.15343528985977173},{"id":"https://openalex.org/C101762097","wikidata":"https://www.wikidata.org/wiki/Q224093","display_name":"Promoter","level":4,"score":0.1428426206111908}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1158/1538-7445.am2020-lb-184","doi":"https://doi.org/10.1158/1538-7445.am2020-lb-184","is_oa":false,"landing_page_url":"https://doi.org/10.1158/1538-7445.am2020-lb-184","pdf_url":null,"source":{"id":"https://openalex.org/S168522863","display_name":"Cancer Research","issn_l":"0008-5472","issn":["0008-5472","1538-7445"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320273","host_organization_name":"American Association for Cancer Research","host_organization_lineage":["https://openalex.org/P4310320273"],"host_organization_lineage_names":["American Association for Cancer Research"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer Research","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.8560000061988831}],"sustainable_development_goals_aurora":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.8100000023841858}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W1985063313","https://openalex.org/W2021787959","https://openalex.org/W2040015936","https://openalex.org/W2050076953","https://openalex.org/W1967331412","https://openalex.org/W2349253874","https://openalex.org/W2064874105","https://openalex.org/W2148487263","https://openalex.org/W2073905722","https://openalex.org/W2070516871"],"abstract_inverted_index":{"Abstract":[0],"Long":[1],"non-coding":[2],"RNAs":[3],"(LncRNAs)":[4],"through":[5,187],"interactions":[6],"with":[7,90,136],"other":[8],"cellular":[9],"macromolecules":[10],"drive":[11],"cell":[12,72],"processes":[13],"contributing":[14],"to":[15,100],"important":[16],"cancer":[17,87,138,146],"phenotypes.":[18],"Here":[19],"we":[20,126],"show":[21],"that":[22,128],"HOTAIR,":[23],"a":[24,107,131,142,190],"highly":[25],"up-regulated":[26],"lncRNA":[27],"in":[28,85],"human":[29,35],"colon":[30,37,86],"cancers,":[31],"induces":[32,71,184],"transformation":[33],"of":[34,62,66,78,114,130,189,197,201],"non-transformed":[36],"epithelial":[38],"cells.":[39],"An":[40],"exon":[41],"6":[42],"HOTAIR":[43],"region":[44],"directly":[45],"binds":[46],"the":[47,67,102,115,137,198,202],"histone":[48],"acetyltransferase":[49,182],"PCAF":[50],"(KAT2B).":[51],"The":[52,75],"HOTAIR/PCAF":[53,80,103],"complex":[54,134,183],"regulates":[55],"H3K27":[56],"acetylation":[57],"and":[58,70,88,95,105,121,140,212],"transcriptional":[59,76],"activation":[60,120],"preferentially":[61],"genes":[63],"encoding":[64],"components":[65],"PI3K/AKT/MEK":[68],"pathways":[69],"metabolic":[73,81,191],"reprogramming.":[74],"signature":[77],"this":[79],"circuit":[82],"is":[83],"active":[84],"correlates":[89],"overall":[91],"patient":[92],"survival.":[93],"Topological":[94],"mechanistic":[96],"analyses":[97],"were":[98],"employed":[99],"characterize":[101],"interface":[104],"design":[106],"reversible":[108],"specific":[109],"inhibitor":[110],"(CPDI-1).":[111],"Selective":[112],"blocking":[113],"HOTAIR-PCAF":[116],"interaction,":[117],"suppresses":[118],"AKT":[119],"tumor":[122],"growth.":[123],"In":[124],"conclusion,":[125],"demonstrate":[127],"disruption":[129],"lncRNA-histone":[132,181],"modifier":[133],"interferes":[135],"epigenome":[139],"represents":[141],"novel":[143],"approach":[144],"for":[145,205],"therapeutics.":[147],"Citation":[148],"Format:":[149],"Christos":[150],"Polytarchou,":[151],"Maria":[152],"Hatziapostolou,":[153],"Marina":[154],"Koutsioumpa,":[155],"Niki":[156],"Christodoulou,":[157],"Tung":[158],"On":[159],"Yau,":[160],"Eleni":[161],"Birli,":[162],"Odette":[163],"Pomenya,":[164],"Cristina":[165],"Montiel-Duarte,":[166],"Swapna":[167],"Mahurkar":[168],"Joshi,":[169],"Daniel":[170],"W.":[171,174],"Hommes,":[172],"Hein":[173],"Verspaget,":[175],"Jun":[176,213],"Yu,":[177],"Dimitrios":[178],"Iliopoulos.":[179],"A":[180],"colorectal":[185],"oncogenesis":[186],"regulation":[188],"kinase":[192],"network":[193],"[abstract].":[194],"In:":[195],"Proceedings":[196],"Annual":[199],"Meeting":[200],"American":[203],"Association":[204],"Cancer":[206,218],"Research":[207],"2020;":[208],"2020":[209],"Apr":[210],"27-28":[211],"22-24.":[214],"Philadelphia":[215],"(PA):":[216],"AACR;":[217],"Res":[219],"2020;80(16":[220],"Suppl):Abstract":[221],"nr":[222],"LB-184.":[223]},"counts_by_year":[],"updated_date":"2026-10-16T09:59:22.235173","created_date":"2025-10-10T00:00:00"}