{"id":"https://openalex.org/W3082787553","doi":null,"title":"Effects Of Chronic Stress On The Pituitary Adenylate Cyclase Activating Polypeptide (pacap) In The Bed Nucleus Of The Stria Terminalis (bnst)","display_name":"Effects Of Chronic Stress On The Pituitary Adenylate Cyclase Activating Polypeptide (pacap) In The Bed Nucleus Of The Stria Terminalis (bnst)","publication_year":2020,"publication_date":"2020-01-01","ids":{"openalex":"https://openalex.org/W3082787553","mag":"3082787553"},"language":"en","primary_location":{"id":"pmh:oai:scholarworks.uvm.edu:graddis-2274","doi":null,"is_oa":true,"landing_page_url":"https://scholarworks.uvm.edu/graddis/1273","pdf_url":"https://scholarworks.uvm.edu/cgi/viewcontent.cgi?article=2274&context=graddis","source":{"id":"https://openalex.org/S4377196529","display_name":"ScholarWorks -A service of University of Vermont Libraries (University of Vermont)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I111236770","host_organization_name":"University of Vermont","host_organization_lineage":["https://openalex.org/I111236770"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Graduate College Dissertations and Theses","raw_type":"text"},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://scholarworks.uvm.edu/cgi/viewcontent.cgi?article=2274&context=graddis","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5011271493","display_name":"Mahafuza Aktar","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Mahafuza Aktar","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5011271493"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.08660204,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10814","display_name":"Neuropeptides and Animal Physiology","score":0.9951000213623047,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10814","display_name":"Neuropeptides and Animal Physiology","score":0.9951000213623047,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10529","display_name":"Stress Responses and Cortisol","score":0.003800000064074993,"subfield":{"id":"https://openalex.org/subfields/2802","display_name":"Behavioral Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10489","display_name":"Regulation of Appetite and Obesity","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2807","display_name":"Endocrine and Autonomic Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/chronic-stress","display_name":"chronic stress","score":0.9869999885559082},{"id":"https://openalex.org/keywords/pacap","display_name":"PACAP","score":0.7400000095367432},{"id":"https://openalex.org/keywords/bed-nucleus-of-the-stria-terminalis","display_name":"bed nucleus of the stria terminalis","score":0.9300000071525574},{"id":"https://openalex.org/keywords/pac1-receptor","display_name":"PAC1 receptor","score":0.7630000114440918},{"id":"https://openalex.org/keywords/anxiety-like-behavior","display_name":"anxiety-like behavior","score":0.9829999804496765},{"id":"https://openalex.org/keywords/hypothalamus","display_name":"hypothalamus","score":0.734000027179718},{"id":"https://openalex.org/keywords/weight-gain","display_name":"weight gain","score":0.531000018119812}],"concepts":[{"id":"https://openalex.org/C2778652331","wikidata":"https://www.wikidata.org/wiki/Q3122152","display_name":"Stria terminalis","level":3,"score":0.9596107006072998},{"id":"https://openalex.org/C180526460","wikidata":"https://www.wikidata.org/wiki/Q356240","display_name":"Adenylate kinase","level":3,"score":0.8141274452209473},{"id":"https://openalex.org/C2780069284","wikidata":"https://www.wikidata.org/wiki/Q5198121","display_name":"Cyclase","level":3,"score":0.7281750440597534},{"id":"https://openalex.org/C2780723820","wikidata":"https://www.wikidata.org/wiki/Q1934178","display_name":"Nucleus","level":2,"score":0.7196388244628906},{"id":"https://openalex.org/C2779496938","wikidata":"https://www.wikidata.org/wiki/Q14907479","display_name":"Pituitary adenylate cyclase-activating peptide","level":5,"score":0.6356576681137085},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.5474021434783936},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5303723812103271},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3658181428909302},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.36041057109832764},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.2858389616012573},{"id":"https://openalex.org/C118303440","wikidata":"https://www.wikidata.org/wiki/Q419968","display_name":"Neuropeptide","level":3,"score":0.2825324535369873},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.16510796546936035},{"id":"https://openalex.org/C24998067","wikidata":"https://www.wikidata.org/wiki/Q4114622","display_name":"Stimulation","level":2,"score":0.14526909589767456},{"id":"https://openalex.org/C8330315","wikidata":"https://www.wikidata.org/wiki/Q414964","display_name":"Vasoactive intestinal peptide","level":4,"score":0.13569802045822144},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.08731552958488464}],"mesh":[],"locations_count":3,"locations":[{"id":"pmh:oai:scholarworks.uvm.edu:graddis-2274","doi":null,"is_oa":true,"landing_page_url":"https://scholarworks.uvm.edu/graddis/1273","pdf_url":"https://scholarworks.uvm.edu/cgi/viewcontent.cgi?article=2274&context=graddis","source":{"id":"https://openalex.org/S4377196529","display_name":"ScholarWorks -A service of University of Vermont Libraries (University of Vermont)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I111236770","host_organization_name":"University of Vermont","host_organization_lineage":["https://openalex.org/I111236770"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Graduate College Dissertations and Theses","raw_type":"text"},{"id":"pmh:oai:scholarworks.uvm.edu:20.500.14849/3198","doi":null,"is_oa":false,"landing_page_url":"https://hdl.handle.net/20.500.14849/3198","pdf_url":null,"source":{"id":"https://openalex.org/S4377196529","display_name":"ScholarWorks -A service of University of Vermont Libraries (University of Vermont)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I111236770","host_organization_name":"University of Vermont","host_organization_lineage":["https://openalex.org/I111236770"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"thesis"},{"id":"mag:3082787553","doi":null,"is_oa":false,"landing_page_url":"https://scholarworks.uvm.edu/cgi/viewcontent.cgi?article=2274&context=graddis","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"pmh:oai:scholarworks.uvm.edu:graddis-2274","doi":null,"is_oa":true,"landing_page_url":"https://scholarworks.uvm.edu/graddis/1273","pdf_url":"https://scholarworks.uvm.edu/cgi/viewcontent.cgi?article=2274&context=graddis","source":{"id":"https://openalex.org/S4377196529","display_name":"ScholarWorks -A service of University of Vermont Libraries (University of Vermont)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I111236770","host_organization_name":"University of Vermont","host_organization_lineage":["https://openalex.org/I111236770"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Graduate College Dissertations and Theses","raw_type":"text"},"sustainable_development_goals":[{"score":0.9476000070571899,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3082787553.pdf","grobid_xml":"https://content.openalex.org/works/W3082787553.grobid-xml"},"referenced_works_count":66,"referenced_works":["https://openalex.org/W1754932253","https://openalex.org/W1966990176","https://openalex.org/W1968309695","https://openalex.org/W1969178781","https://openalex.org/W1972368693","https://openalex.org/W1975765156","https://openalex.org/W1980549608","https://openalex.org/W1983996585","https://openalex.org/W1988051217","https://openalex.org/W1988718994","https://openalex.org/W1997975361","https://openalex.org/W2000362647","https://openalex.org/W2004626419","https://openalex.org/W2008280777","https://openalex.org/W2010638458","https://openalex.org/W2010778222","https://openalex.org/W2011431839","https://openalex.org/W2012367545","https://openalex.org/W2012458220","https://openalex.org/W2013556329","https://openalex.org/W2025860749","https://openalex.org/W2029947470","https://openalex.org/W2033137859","https://openalex.org/W2033316597","https://openalex.org/W2036047394","https://openalex.org/W2047197211","https://openalex.org/W2047523044","https://openalex.org/W2048595206","https://openalex.org/W2060737262","https://openalex.org/W2060982579","https://openalex.org/W2061111210","https://openalex.org/W2061807141","https://openalex.org/W2068480672","https://openalex.org/W2070784027","https://openalex.org/W2073676810","https://openalex.org/W2074161010","https://openalex.org/W2075200723","https://openalex.org/W2079927878","https://openalex.org/W2084216483","https://openalex.org/W2091854576","https://openalex.org/W2094646973","https://openalex.org/W2097613394","https://openalex.org/W2111407966","https://openalex.org/W2115294869","https://openalex.org/W2123865806","https://openalex.org/W2126257863","https://openalex.org/W2136403062","https://openalex.org/W2141050240","https://openalex.org/W2145865543","https://openalex.org/W2148991048","https://openalex.org/W2156466346","https://openalex.org/W2156837840","https://openalex.org/W2156979070","https://openalex.org/W2160115379","https://openalex.org/W2162227712","https://openalex.org/W2264430018","https://openalex.org/W2357264154","https://openalex.org/W2491422019","https://openalex.org/W2531618378","https://openalex.org/W2572875486","https://openalex.org/W2626370384","https://openalex.org/W2783650089","https://openalex.org/W2899237877","https://openalex.org/W2902217593","https://openalex.org/W2956601333","https://openalex.org/W3003492219"],"related_works":["https://openalex.org/W7098279115","https://openalex.org/W2336334484","https://openalex.org/W1975765156","https://openalex.org/W2111407966","https://openalex.org/W2126257863","https://openalex.org/W2572875486","https://openalex.org/W6996366166","https://openalex.org/W2981331644","https://openalex.org/W7024212977","https://openalex.org/W2073676810"],"abstract_inverted_index":{"Exposure":[0],"to":[1,84],"chronic":[2,16,56,80,101,110],"stressors":[3],"can":[4],"produce":[5],"maladaptive":[6],"behavioral":[7,113,137],"and":[8,23,31,97,114,119,127],"physiological":[9,115],"consequences.":[10],"Previous":[11],"work":[12],"has":[13,112],"demonstrated":[14],"that":[15,52,109,120],"variant":[17,57],"stress":[18,58,111],"exposure":[19,82],"enhances":[20],"anxiety-like":[21,61],"behavior":[22,62],"increases":[24],"pituitary":[25],"adenylate":[26],"cyclase":[27],"activating":[28],"polypeptide":[29],"(PACAP)":[30],"PAC1":[32],"receptor":[33],"transcripts":[34],"in":[35,45,63,93,117,123,135],"the":[36,41,68,76,94,124,128],"anterolateral":[37],"bed":[38],"nucleus":[39],"of":[40,79],"stria":[42],"terminalis":[43],"(BNST)":[44],"rats.":[46],"The":[47],"studies":[48],"described":[49],"here":[50],"demonstrate":[51],"treatment":[53],"with":[54],"a":[55,133],"paradigm":[59],"produced":[60],"transgenic":[64],"PACAP-Cre":[65],"mice.":[66,86],"Additionally,":[67],"stressed":[69],"group":[70],"did":[71],"not":[72],"gain":[73],"weight":[74],"during":[75],"14":[77],"days":[78],"stressor":[81],"compared":[83],"control":[85],"Furthermore,":[87],"fewer":[88],"PACAP-expressing":[89],"neurons":[90],"were":[91],"observed":[92],"posterior":[95,125],"BNST":[96,126],"lateral":[98,129],"hypothalamus":[99,130],"following":[100],"variate":[102],"stress.":[103],"In":[104],"aggregate,":[105],"these":[106,136],"data":[107],"suggest":[108],"consequences":[116],"mice":[118],"PACAP":[121],"systems":[122],"may":[131],"play":[132],"role":[134],"changes.":[138]},"counts_by_year":[],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2020-09-08T00:00:00"}