{"id":"https://openalex.org/W3082017735","doi":"https://doi.org/10.11604/pamj.2020.36.367.25116","title":"Systemic lupus erythematosus, antiphospholipid syndrome and Hashimoto thyroiditis occurring in a patient with Niemann-Pick disease: a second case","display_name":"Systemic lupus erythematosus, antiphospholipid syndrome and Hashimoto thyroiditis occurring in a patient with Niemann-Pick disease: a second case","publication_year":2020,"publication_date":"2020-01-01","ids":{"openalex":"https://openalex.org/W3082017735","doi":"https://doi.org/10.11604/pamj.2020.36.367.25116","mag":"3082017735","pmid":"https://pubmed.ncbi.nlm.nih.gov/33235644","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/7666682"},"language":"en","primary_location":{"id":"doi:10.11604/pamj.2020.36.367.25116","doi":"https://doi.org/10.11604/pamj.2020.36.367.25116","is_oa":true,"landing_page_url":"https://doi.org/10.11604/pamj.2020.36.367.25116","pdf_url":null,"source":{"id":"https://openalex.org/S2755481371","display_name":"Pan African Medical Journal","issn_l":"1937-8688","issn":["1937-8688"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","jpps-2","medline","poland-20","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310311037","host_organization_name":"African Field Epidemiology Network","host_organization_lineage":["https://openalex.org/P4310311037"],"host_organization_lineage_names":["African Field Epidemiology Network"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pan African Medical Journal","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","datacite","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.11604/pamj.2020.36.367.25116","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5063396197","display_name":"Wafa Baya","orcid":"https://orcid.org/0000-0003-1358-5266","observed_orcids":["https://orcid.org/0000-0003-1358-5266"]},"institutions":[{"id":"https://openalex.org/I4210148482","display_name":"H\u00f4pital Sahloul","ror":"https://ror.org/043z88g18","country_code":"TN","type":"healthcare","lineage":["https://openalex.org/I4210148482"]},{"id":"https://openalex.org/I8636806","display_name":"University of Sousse","ror":"https://ror.org/00dmpgj58","country_code":"TN","type":"education","lineage":["https://openalex.org/I8636806"]}],"countries":["TN"],"is_corresponding":true,"raw_author_name":"Wafa Baya","raw_affiliation_strings":["Universit\u00e9 de Sousse, Facult\u00e9 de M\u00e9decine de Sousse, H\u00f4pital Sahloul, Service de M\u00e9decine Interne, Unit\u00e9 de G\u00e9rontologie et G\u00e9riatrie Clinique, 4000, Sousse, Tunisie"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Universit\u00e9 de Sousse, Facult\u00e9 de M\u00e9decine de Sousse, H\u00f4pital Sahloul, Service de M\u00e9decine Interne, Unit\u00e9 de G\u00e9rontologie et G\u00e9riatrie Clinique, 4000, Sousse, Tunisie","institution_ids":["https://openalex.org/I4210148482","https://openalex.org/I8636806"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065553331","display_name":"Fatma Ben Fredj","orcid":"https://orcid.org/0000-0002-2850-816X","observed_orcids":["https://orcid.org/0000-0002-2850-816X"]},"institutions":[{"id":"https://openalex.org/I4210148482","display_name":"H\u00f4pital Sahloul","ror":"https://ror.org/043z88g18","country_code":"TN","type":"healthcare","lineage":["https://openalex.org/I4210148482"]},{"id":"https://openalex.org/I8636806","display_name":"University of Sousse","ror":"https://ror.org/00dmpgj58","country_code":"TN","type":"education","lineage":["https://openalex.org/I8636806"]}],"countries":["TN"],"is_corresponding":false,"raw_author_name":"Fatma Ben Fredj","raw_affiliation_strings":["Universit\u00e9 de Sousse, Facult\u00e9 de M\u00e9decine de Sousse, H\u00f4pital Sahloul, Service de M\u00e9decine Interne, Unit\u00e9 de G\u00e9rontologie et G\u00e9riatrie Clinique, 4000, Sousse, Tunisie"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Universit\u00e9 de Sousse, Facult\u00e9 de M\u00e9decine de Sousse, H\u00f4pital Sahloul, Service de M\u00e9decine Interne, Unit\u00e9 de G\u00e9rontologie et G\u00e9riatrie Clinique, 4000, Sousse, Tunisie","institution_ids":["https://openalex.org/I4210148482","https://openalex.org/I8636806"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110628911","display_name":"Imen Ben Hassine","orcid":"https://orcid.org/0000-0001-5459-3460","observed_orcids":["https://orcid.org/0000-0001-5459-3460"]},"institutions":[{"id":"https://openalex.org/I4210148482","display_name":"H\u00f4pital Sahloul","ror":"https://ror.org/043z88g18","country_code":"TN","type":"healthcare","lineage":["https://openalex.org/I4210148482"]},{"id":"https://openalex.org/I8636806","display_name":"University of Sousse","ror":"https://ror.org/00dmpgj58","country_code":"TN","type":"education","lineage":["https://openalex.org/I8636806"]}],"countries":["TN"],"is_corresponding":false,"raw_author_name":"Imen Ben Hassine","raw_affiliation_strings":["Universit\u00e9 de Sousse, Facult\u00e9 de M\u00e9decine de Sousse, H\u00f4pital Sahloul, Service de M\u00e9decine Interne, Unit\u00e9 de G\u00e9rontologie et G\u00e9riatrie Clinique, 4000, Sousse, Tunisie"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Universit\u00e9 de Sousse, Facult\u00e9 de M\u00e9decine de Sousse, H\u00f4pital Sahloul, Service de M\u00e9decine Interne, Unit\u00e9 de G\u00e9rontologie et G\u00e9riatrie Clinique, 4000, Sousse, Tunisie","institution_ids":["https://openalex.org/I4210148482","https://openalex.org/I8636806"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081966293","display_name":"J. Anoun","orcid":"https://orcid.org/0000-0002-5441-6867","observed_orcids":["https://orcid.org/0000-0002-5441-6867"]},"institutions":[{"id":"https://openalex.org/I4210148482","display_name":"H\u00f4pital Sahloul","ror":"https://ror.org/043z88g18","country_code":"TN","type":"healthcare","lineage":["https://openalex.org/I4210148482"]},{"id":"https://openalex.org/I8636806","display_name":"University of Sousse","ror":"https://ror.org/00dmpgj58","country_code":"TN","type":"education","lineage":["https://openalex.org/I8636806"]}],"countries":["TN"],"is_corresponding":false,"raw_author_name":"Jihed Anoun","raw_affiliation_strings":["Universit\u00e9 de Sousse, Facult\u00e9 de M\u00e9decine de Sousse, H\u00f4pital Sahloul, Service de M\u00e9decine Interne, Unit\u00e9 de G\u00e9rontologie et G\u00e9riatrie Clinique, 4000, Sousse, Tunisie"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Universit\u00e9 de Sousse, Facult\u00e9 de M\u00e9decine de Sousse, H\u00f4pital Sahloul, Service de M\u00e9decine Interne, Unit\u00e9 de G\u00e9rontologie et G\u00e9riatrie Clinique, 4000, Sousse, Tunisie","institution_ids":["https://openalex.org/I4210148482","https://openalex.org/I8636806"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102805784","display_name":"A. Mzabi","orcid":"https://orcid.org/0009-0000-1277-9494","observed_orcids":["https://orcid.org/0009-0000-1277-9494"]},"institutions":[{"id":"https://openalex.org/I4210148482","display_name":"H\u00f4pital Sahloul","ror":"https://ror.org/043z88g18","country_code":"TN","type":"healthcare","lineage":["https://openalex.org/I4210148482"]},{"id":"https://openalex.org/I8636806","display_name":"University of Sousse","ror":"https://ror.org/00dmpgj58","country_code":"TN","type":"education","lineage":["https://openalex.org/I8636806"]}],"countries":["TN"],"is_corresponding":false,"raw_author_name":"Anis Mzabi","raw_affiliation_strings":["Universit\u00e9 de Sousse, Facult\u00e9 de M\u00e9decine de Sousse, H\u00f4pital Sahloul, Service de M\u00e9decine Interne, Unit\u00e9 de G\u00e9rontologie et G\u00e9riatrie Clinique, 4000, Sousse, Tunisie"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Universit\u00e9 de Sousse, Facult\u00e9 de M\u00e9decine de Sousse, H\u00f4pital Sahloul, Service de M\u00e9decine Interne, Unit\u00e9 de G\u00e9rontologie et G\u00e9riatrie Clinique, 4000, Sousse, Tunisie","institution_ids":["https://openalex.org/I4210148482","https://openalex.org/I8636806"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5104085993","display_name":"Monia Karmani","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210148482","display_name":"H\u00f4pital Sahloul","ror":"https://ror.org/043z88g18","country_code":"TN","type":"healthcare","lineage":["https://openalex.org/I4210148482"]},{"id":"https://openalex.org/I8636806","display_name":"University of Sousse","ror":"https://ror.org/00dmpgj58","country_code":"TN","type":"education","lineage":["https://openalex.org/I8636806"]}],"countries":["TN"],"is_corresponding":false,"raw_author_name":"Monia Karmani","raw_affiliation_strings":["Universit\u00e9 de Sousse, Facult\u00e9 de M\u00e9decine de Sousse, H\u00f4pital Sahloul, Service de M\u00e9decine Interne, Unit\u00e9 de G\u00e9rontologie et G\u00e9riatrie Clinique, 4000, Sousse, Tunisie"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Universit\u00e9 de Sousse, Facult\u00e9 de M\u00e9decine de Sousse, H\u00f4pital Sahloul, Service de M\u00e9decine Interne, Unit\u00e9 de G\u00e9rontologie et G\u00e9riatrie Clinique, 4000, Sousse, Tunisie","institution_ids":["https://openalex.org/I4210148482","https://openalex.org/I8636806"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054227560","display_name":"Amel Rezgui","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210148482","display_name":"H\u00f4pital Sahloul","ror":"https://ror.org/043z88g18","country_code":"TN","type":"healthcare","lineage":["https://openalex.org/I4210148482"]},{"id":"https://openalex.org/I8636806","display_name":"University of Sousse","ror":"https://ror.org/00dmpgj58","country_code":"TN","type":"education","lineage":["https://openalex.org/I8636806"]}],"countries":["TN"],"is_corresponding":false,"raw_author_name":"Amel Rezgui","raw_affiliation_strings":["Universit\u00e9 de Sousse, Facult\u00e9 de M\u00e9decine de Sousse, H\u00f4pital Sahloul, Service de M\u00e9decine Interne, Unit\u00e9 de G\u00e9rontologie et G\u00e9riatrie Clinique, 4000, Sousse, Tunisie"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Universit\u00e9 de Sousse, Facult\u00e9 de M\u00e9decine de Sousse, H\u00f4pital Sahloul, Service de M\u00e9decine Interne, Unit\u00e9 de G\u00e9rontologie et G\u00e9riatrie Clinique, 4000, Sousse, Tunisie","institution_ids":["https://openalex.org/I4210148482","https://openalex.org/I8636806"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036436322","display_name":"Mohamed Adn\u00e8ne Laatiri","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I166928557","display_name":"University of Monastir","ror":"https://ror.org/00nhtcg76","country_code":"TN","type":"education","lineage":["https://openalex.org/I166928557"]},{"id":"https://openalex.org/I4210167430","display_name":"Hospital Fatuma Bourguiba Monastir","ror":"https://ror.org/05t1yee64","country_code":"TN","type":"healthcare","lineage":["https://openalex.org/I4210167430"]}],"countries":["TN"],"is_corresponding":false,"raw_author_name":"Mohamed Adnane Laatiri","raw_affiliation_strings":["Service d\u00b4H\u00e9matologie Clinique, H\u00f4pital Universitaire Fattouma Bourguiba, Facult\u00e9 de M\u00e9decine, Universit\u00e9 de Monastir, 5019, Monastir, Tunisie"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Service d\u00b4H\u00e9matologie Clinique, H\u00f4pital Universitaire Fattouma Bourguiba, Facult\u00e9 de M\u00e9decine, Universit\u00e9 de Monastir, 5019, Monastir, Tunisie","institution_ids":["https://openalex.org/I166928557","https://openalex.org/I4210167430"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5109318007","display_name":"C. Laouani Kechrid","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210148482","display_name":"H\u00f4pital Sahloul","ror":"https://ror.org/043z88g18","country_code":"TN","type":"healthcare","lineage":["https://openalex.org/I4210148482"]},{"id":"https://openalex.org/I8636806","display_name":"University of Sousse","ror":"https://ror.org/00dmpgj58","country_code":"TN","type":"education","lineage":["https://openalex.org/I8636806"]}],"countries":["TN"],"is_corresponding":false,"raw_author_name":"Chedia Laouani Kechrid","raw_affiliation_strings":["Universit\u00e9 de Sousse, Facult\u00e9 de M\u00e9decine de Sousse, H\u00f4pital Sahloul, Service de M\u00e9decine Interne, Unit\u00e9 de G\u00e9rontologie et G\u00e9riatrie Clinique, 4000, Sousse, Tunisie"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Universit\u00e9 de Sousse, Facult\u00e9 de M\u00e9decine de Sousse, H\u00f4pital Sahloul, Service de M\u00e9decine Interne, Unit\u00e9 de G\u00e9rontologie et G\u00e9riatrie Clinique, 4000, Sousse, Tunisie","institution_ids":["https://openalex.org/I4210148482","https://openalex.org/I8636806"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5063396197"],"corresponding_institution_ids":["https://openalex.org/I4210148482","https://openalex.org/I8636806"],"apc_list":{"value":180,"currency":"USD","value_usd":180},"apc_paid":{"value":180,"currency":"USD","value_usd":180},"fwci":0.4764,"has_fulltext":true,"cited_by_count":8,"citation_normalized_percentile":{"value":0.60898941,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":96},"biblio":{"volume":"36","issue":null,"first_page":"367","last_page":"367"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10308","display_name":"Systemic Lupus Erythematosus Research","score":0.9907000064849854,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10308","display_name":"Systemic Lupus Erythematosus Research","score":0.9907000064849854,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10945","display_name":"Lysosomal Storage Disorders Research","score":0.007699999958276749,"subfield":{"id":"https://openalex.org/subfields/2716","display_name":"Genetics (clinical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10697","display_name":"Vasculitis and related conditions","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/niemann-pick-disease-type-b","display_name":"Niemann-Pick disease type B","score":0.972000002861023},{"id":"https://openalex.org/keywords/systemic-lupus-erythematosus","display_name":"systemic lupus erythematosus","score":0.9919999837875366},{"id":"https://openalex.org/keywords/antiphospholipid-syndrome","display_name":"antiphospholipid syndrome","score":1.0},{"id":"https://openalex.org/keywords/hashimoto-s-thyroiditis","display_name":"Hashimoto's thyroiditis","score":0.9990000128746033},{"id":"https://openalex.org/keywords/lysosomal-storage-disorders","display_name":"lysosomal storage disease","score":0.7540000081062317},{"id":"https://openalex.org/keywords/autoimmune-disease","display_name":"autoimmune disease","score":0.7300000190734863},{"id":"https://openalex.org/keywords/anticardiolipin-antibodies","display_name":"anticardiolipin antibodies","score":0.8560000061988831},{"id":"https://openalex.org/keywords/anti-beta2-glycoprotein-i-antibodies","display_name":"anti-beta2-glycoprotein I antibodies","score":0.925000011920929},{"id":"https://openalex.org/keywords/pulmonary-embolism","display_name":"pulmonary embolism","score":0.9829999804496765},{"id":"https://openalex.org/keywords/hemolytic-anemia","display_name":"hemolytic anemia","score":0.7689999938011169},{"id":"https://openalex.org/keywords/cyclophosphamide","display_name":"cyclophosphamide","score":0.949999988079071},{"id":"https://openalex.org/keywords/steroid-dependence","display_name":"steroid dependence","score":0.8399999737739563},{"id":"https://openalex.org/keywords/hydroxychloroquine","display_name":"hydroxychloroquine","score":0.7749999761581421},{"id":"https://openalex.org/keywords/anticoagulation","display_name":"anticoagulation","score":0.7929999828338623}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9784619212150574},{"id":"https://openalex.org/C2779123688","wikidata":"https://www.wikidata.org/wiki/Q421094","display_name":"Hydroxychloroquine","level":5,"score":0.7519923448562622},{"id":"https://openalex.org/C2776874634","wikidata":"https://www.wikidata.org/wiki/Q582207","display_name":"Antiphospholipid syndrome","level":3,"score":0.7218289971351624},{"id":"https://openalex.org/C2778696486","wikidata":"https://www.wikidata.org/wiki/Q11835644","display_name":"Thyroiditis","level":3,"score":0.5907421112060547},{"id":"https://openalex.org/C2776755627","wikidata":"https://www.wikidata.org/wiki/Q408524","display_name":"Cyclophosphamide","level":3,"score":0.5319602489471436},{"id":"https://openalex.org/C2775883008","wikidata":"https://www.wikidata.org/wiki/Q773449","display_name":"Levothyroxine","level":3,"score":0.4740866422653198},{"id":"https://openalex.org/C2779974317","wikidata":"https://www.wikidata.org/wiki/Q2003151","display_name":"Livedo reticularis","level":3,"score":0.46364203095436096},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.43032339215278625},{"id":"https://openalex.org/C2780022809","wikidata":"https://www.wikidata.org/wiki/Q5786759","display_name":"Lupus anticoagulant","level":3,"score":0.42987293004989624},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.420910120010376},{"id":"https://openalex.org/C16005928","wikidata":"https://www.wikidata.org/wiki/Q171171","display_name":"Dermatology","level":1,"score":0.41573160886764526},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3553726077079773},{"id":"https://openalex.org/C526584372","wikidata":"https://www.wikidata.org/wiki/Q16399","display_name":"Thyroid","level":2,"score":0.18712139129638672},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.142581045627594},{"id":"https://openalex.org/C2776694085","wikidata":"https://www.wikidata.org/wiki/Q974135","display_name":"Chemotherapy","level":2,"score":0.11290571093559265},{"id":"https://openalex.org/C3008058167","wikidata":"https://www.wikidata.org/wiki/Q84263196","display_name":"Coronavirus disease 2019 (COVID-19)","level":4,"score":0.0},{"id":"https://openalex.org/C524204448","wikidata":"https://www.wikidata.org/wiki/Q788926","display_name":"Infectious disease (medical specialty)","level":3,"score":0.0}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004417","descriptor_name":"Dyspnea","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008180","descriptor_name":"Lupus Erythematosus, Systemic","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D008180","descriptor_name":"Lupus Erythematosus, Systemic","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D009542","descriptor_name":"Niemann-Pick Diseases","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D009542","descriptor_name":"Niemann-Pick Diseases","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D011655","descriptor_name":"Pulmonary Embolism","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D014057","descriptor_name":"Tomography, X-Ray Computed","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016736","descriptor_name":"Antiphospholipid Syndrome","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D016736","descriptor_name":"Antiphospholipid Syndrome","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D050031","descriptor_name":"Hashimoto Disease","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D050031","descriptor_name":"Hashimoto Disease","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false}],"locations_count":6,"locations":[{"id":"doi:10.11604/pamj.2020.36.367.25116","doi":"https://doi.org/10.11604/pamj.2020.36.367.25116","is_oa":true,"landing_page_url":"https://doi.org/10.11604/pamj.2020.36.367.25116","pdf_url":null,"source":{"id":"https://openalex.org/S2755481371","display_name":"Pan African Medical Journal","issn_l":"1937-8688","issn":["1937-8688"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","jpps-2","medline","poland-20","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310311037","host_organization_name":"African Field Epidemiology Network","host_organization_lineage":["https://openalex.org/P4310311037"],"host_organization_lineage_names":["African Field Epidemiology Network"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pan African Medical Journal","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:7666682","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC7666682/","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC7666682/pdf/","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pan Afr Med J","raw_type":"Text"},{"id":"pmid:33235644","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/33235644","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Pan African medical journal","raw_type":"Case Reports"},{"id":"pmh:oai:doaj.org/article:5b7c2f2caa6748a69577bd574d9b1905","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/5b7c2f2caa6748a69577bd574d9b1905","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"The Pan African Medical Journal, Vol 36, Iss 367 (2020)","raw_type":"article"},{"id":"doi:10.60692/gk9y1-9wc48","doi":"https://doi.org/10.60692/gk9y1-9wc48","is_oa":true,"landing_page_url":"https://doi.org/10.60692/gk9y1-9wc48","pdf_url":null,"source":{"id":"https://openalex.org/S7407051682","display_name":"Greater South Information System","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"article-journal"},{"id":"doi:10.60692/pn5tm-wht28","doi":"https://doi.org/10.60692/pn5tm-wht28","is_oa":true,"landing_page_url":"https://doi.org/10.60692/pn5tm-wht28","pdf_url":null,"source":{"id":"https://openalex.org/S7407051682","display_name":"Greater South Information System","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"article-journal"}],"best_oa_location":{"id":"doi:10.11604/pamj.2020.36.367.25116","doi":"https://doi.org/10.11604/pamj.2020.36.367.25116","is_oa":true,"landing_page_url":"https://doi.org/10.11604/pamj.2020.36.367.25116","pdf_url":null,"source":{"id":"https://openalex.org/S2755481371","display_name":"Pan African Medical Journal","issn_l":"1937-8688","issn":["1937-8688"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","jpps-2","medline","poland-20","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310311037","host_organization_name":"African Field Epidemiology Network","host_organization_lineage":["https://openalex.org/P4310311037"],"host_organization_lineage_names":["African Field Epidemiology Network"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pan African Medical Journal","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":1.0,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Case Report","id":"https://openalex.org/study-designs/case-report"}],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3082017735.pdf","grobid_xml":"https://content.openalex.org/works/W3082017735.grobid-xml"},"referenced_works_count":10,"referenced_works":["https://openalex.org/W199204758","https://openalex.org/W2000167798","https://openalex.org/W2025782555","https://openalex.org/W2053790198","https://openalex.org/W2132551929","https://openalex.org/W2241208770","https://openalex.org/W2283136208","https://openalex.org/W2605988729","https://openalex.org/W2618043834","https://openalex.org/W2917793154"],"related_works":["https://openalex.org/W7118083754","https://openalex.org/W2283136208","https://openalex.org/W2000744192","https://openalex.org/W4390595479","https://openalex.org/W1881577074","https://openalex.org/W3032239177","https://openalex.org/W7217466810","https://openalex.org/W2158510068","https://openalex.org/W4400789009","https://openalex.org/W4401185339"],"abstract_inverted_index":{"Lysosomial":[0],"diseases":[1,4],"and":[2,41,94,101,126,139],"autoimmune":[3],"are":[5],"systemic":[6,32],"disorders.":[7],"Their":[8,20],"clinical":[9],"manifestations":[10],"can":[11],"overlap":[12],"with":[13,55,63,82,88,97,121],"the":[14,69],"broad":[15],"spectrum":[16],"of":[17,31,59,71,79,136],"one":[18],"another.":[19],"association":[21],"has":[22],"been":[23],"rarely":[24],"reported.":[25],"We":[26],"report":[27],"a":[28,56,64,109],"new":[29],"case":[30],"lupus":[33],"erythematous":[34],"(SLE)":[35],"associated":[36],"to":[37,91],"antiphospholipid":[38],"syndrome":[39,115],"(APS)":[40],"Hashimoto":[42,95],"thyroiditis":[43],"occurring":[44],"in":[45],"Niemann-Pick":[46],"disease":[47,96],"(NPD)":[48],"type":[49,66],"B":[50,67],"patient.":[51],"A":[52],"42-year-old":[53],"woman":[54],"familial":[57],"history":[58],"NPD":[60,65],"was":[61,86,116,119,131],"diagnosed":[62,87],"at":[68],"age":[70],"ten.":[72],"Twenty":[73],"years":[74],"later":[75],"(2008),":[76],"she":[77,107],"complained":[78],"inflammatory":[80],"arthralgia":[81],"acute":[83],"dyspnea.":[84],"She":[85,118],"SLE":[89,129],"(according":[90],"ACR":[92],"criteria)":[93],"positive":[98],"IgG":[99],"anti-cardiolipin":[100],"IgA":[102],"anti-beta2":[103],"glycoprotein.":[104],"In":[105],"2018,":[106],"presented":[108],"left":[110],"segmental":[111],"pulmonary":[112],"embolism.":[113],"Antiphospholipid":[114],"retained.":[117],"treated":[120],"steroids,":[122],"hydroxychloroquine,":[123],"anticoagulation":[124],"therapy":[125],"levothyroxine.":[127],"Her":[128],"treatment":[130],"re-enforced":[132],"by":[133],"cyclophosphamide":[134],"because":[135],"corticosteroid":[137],"dependence":[138],"recurrent":[140],"hemolytic":[141],"crises.":[142]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":3},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":1}],"updated_date":"2026-11-12T12:28:57.059296","created_date":"2020-09-08T00:00:00"}