{"id":"https://openalex.org/W3081964482","doi":"https://doi.org/10.1089/biores.2020.0013","title":"Optimization of Sorghum Kafirin Extraction Conditions and Identification of Potential Bioactive Peptides","display_name":"Optimization of Sorghum Kafirin Extraction Conditions and Identification of Potential Bioactive Peptides","publication_year":2020,"publication_date":"2020-09-01","ids":{"openalex":"https://openalex.org/W3081964482","doi":"https://doi.org/10.1089/biores.2020.0013","mag":"3081964482","pmid":"https://pubmed.ncbi.nlm.nih.gov/32923174","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/7484892"},"language":"en","primary_location":{"id":"doi:10.1089/biores.2020.0013","doi":"https://doi.org/10.1089/biores.2020.0013","is_oa":true,"landing_page_url":"https://doi.org/10.1089/biores.2020.0013","pdf_url":"https://www.liebertpub.com/doi/pdf/10.1089/biores.2020.0013","source":{"id":"https://openalex.org/S4210180731","display_name":"BioResearch open access","issn_l":"2164-7844","issn":["2164-7844","2164-7860"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1","ki-jl-1","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320443","host_organization_name":"Mary Ann Liebert, Inc.","host_organization_lineage":["https://openalex.org/P4310320443","https://openalex.org/P4310320017"],"host_organization_lineage_names":["Mary Ann Liebert, Inc.","SAGE Publishing"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BioResearch Open Access","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://www.liebertpub.com/doi/pdf/10.1089/biores.2020.0013","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5061876284","display_name":"Tania Patricia Castro-J\u00e1come","orcid":"https://orcid.org/0000-0003-0859-0140","observed_orcids":["https://orcid.org/0000-0003-0859-0140"]},"institutions":[{"id":"https://openalex.org/I4210131529","display_name":"Instituto Tecnol\u00f3gico de Tepic","ror":"https://ror.org/0377f1g25","country_code":"MX","type":"education","lineage":["https://openalex.org/I4210131529"]}],"countries":["MX"],"is_corresponding":false,"raw_author_name":"Tania P. Castro-J\u00e1come","raw_affiliation_strings":["Instituto Tecnol\u00f3gico de Tepic. Av. Tecnol\u00f3gico No. 2595, Col. Lagos del Country, Tepic, Nayarit, M\u00e9xico"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Instituto Tecnol\u00f3gico de Tepic. Av. Tecnol\u00f3gico No. 2595, Col. Lagos del Country, Tepic, Nayarit, M\u00e9xico","institution_ids":["https://openalex.org/I4210131529"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5080614335","display_name":"Luz Eugenia Alc\u00e1ntara-Quintana","orcid":"https://orcid.org/0000-0003-2961-9838","observed_orcids":["https://orcid.org/0000-0003-2961-9838"]},"institutions":[{"id":"https://openalex.org/I196664497","display_name":"Autonomous University of San Luis Potos\u00ed","ror":"https://ror.org/000917t60","country_code":"MX","type":"education","lineage":["https://openalex.org/I196664497"]}],"countries":["MX"],"is_corresponding":true,"raw_author_name":"Luz E. Alc\u00e1ntara-Quintana","raw_affiliation_strings":["Catedra CONACyT, Facultad de Enfermer\u00eda y Nutrici\u00f3n, Universidad Aut\u00f3noma de San Luis Potos\u00ed, Av. Ni\u00f1o Artillero No. 130, Zona Universitaria, S.L.P., M\u00e9xico"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Catedra CONACyT, Facultad de Enfermer\u00eda y Nutrici\u00f3n, Universidad Aut\u00f3noma de San Luis Potos\u00ed, Av. Ni\u00f1o Artillero No. 130, Zona Universitaria, S.L.P., M\u00e9xico","institution_ids":["https://openalex.org/I196664497"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5011425988","display_name":"Erik Gustavo Tovar-Perez","orcid":"https://orcid.org/0000-0002-4998-4480","observed_orcids":["https://orcid.org/0000-0002-4998-4480"]},"institutions":[{"id":"https://openalex.org/I157492648","display_name":"Autonomous University of Queretaro","ror":"https://ror.org/00v8fdc16","country_code":"MX","type":"education","lineage":["https://openalex.org/I157492648"]}],"countries":["MX"],"is_corresponding":false,"raw_author_name":"Erik G. Tovar-P\u00e9rez","raw_affiliation_strings":["Catedra CONACyT, Facultad de Ingenier\u00eda, Universidad Aut\u00f3noma de Quer\u00e9taro, Carretera Chichimequillas s/n, El Marqu\u00e9s, Quer\u00e9taro, M\u00e9xico"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Catedra CONACyT, Facultad de Ingenier\u00eda, Universidad Aut\u00f3noma de Quer\u00e9taro, Carretera Chichimequillas s/n, El Marqu\u00e9s, Quer\u00e9taro, M\u00e9xico","institution_ids":["https://openalex.org/I157492648"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5080614335"],"corresponding_institution_ids":["https://openalex.org/I196664497"],"apc_list":null,"apc_paid":null,"fwci":2.8,"has_fulltext":true,"cited_by_count":38,"citation_normalized_percentile":{"value":0.89490206,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":95,"max":99},"biblio":{"volume":"9","issue":"1","first_page":"198","last_page":"208"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11561","display_name":"Protein Hydrolysis and Bioactive Peptides","score":0.9932000041007996,"subfield":{"id":"https://openalex.org/subfields/1106","display_name":"Food Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11561","display_name":"Protein Hydrolysis and Bioactive Peptides","score":0.9932000041007996,"subfield":{"id":"https://openalex.org/subfields/1106","display_name":"Food Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10411","display_name":"Proteins in Food Systems","score":0.0010000000474974513,"subfield":{"id":"https://openalex.org/subfields/1106","display_name":"Food Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T14127","display_name":"Food Nutrient Composition and Product Development","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/1106","display_name":"Food Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/extraction-optimization","display_name":"extraction optimization","score":0.8889999985694885},{"id":"https://openalex.org/keywords/bioactive-peptides","display_name":"bioactive peptides","score":0.878000020980835},{"id":"https://openalex.org/keywords/peptide-prediction","display_name":"peptide prediction","score":0.5090000033378601},{"id":"https://openalex.org/keywords/dipeptidyl-peptidase-inhibitors","display_name":"dipeptidyl peptidase inhibitors","score":0.859000027179718},{"id":"https://openalex.org/keywords/ace-inhibitors","display_name":"ACE inhibitors","score":0.9919999837875366},{"id":"https://openalex.org/keywords/antioxidant-peptides","display_name":"antioxidant peptides","score":0.9890000224113464},{"id":"https://openalex.org/keywords/antihypertensive-peptides","display_name":"antihypertensive peptides","score":0.9459999799728394},{"id":"https://openalex.org/keywords/white-sorghum","display_name":"white sorghum","score":0.7710000276565552}],"concepts":[{"id":"https://openalex.org/C31903555","wikidata":"https://www.wikidata.org/wiki/Q1637030","display_name":"Food science","level":1,"score":0.6053129434585571},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5816361308097839},{"id":"https://openalex.org/C4725764","wikidata":"https://www.wikidata.org/wiki/Q844704","display_name":"Extraction (chemistry)","level":2,"score":0.5111938118934631},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.49826669692993164},{"id":"https://openalex.org/C170835558","wikidata":"https://www.wikidata.org/wiki/Q17153","display_name":"Amylase","level":3,"score":0.4981112480163574},{"id":"https://openalex.org/C2779281246","wikidata":"https://www.wikidata.org/wiki/Q172847","display_name":"Peptide","level":2,"score":0.4835509955883026},{"id":"https://openalex.org/C17857428","wikidata":"https://www.wikidata.org/wiki/Q533025","display_name":"Nutraceutical","level":2,"score":0.44083383679389954},{"id":"https://openalex.org/C2780657754","wikidata":"https://www.wikidata.org/wiki/Q7323103","display_name":"Rice protein","level":2,"score":0.42264124751091003},{"id":"https://openalex.org/C2778157034","wikidata":"https://www.wikidata.org/wiki/Q12111","display_name":"Sorghum","level":2,"score":0.42179322242736816},{"id":"https://openalex.org/C2778401398","wikidata":"https://www.wikidata.org/wiki/Q383836","display_name":"Chymotrypsin","level":4,"score":0.4215623140335083},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.3675489127635956},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.29031866788864136},{"id":"https://openalex.org/C2780340462","wikidata":"https://www.wikidata.org/wiki/Q127450","display_name":"Trypsin","level":3,"score":0.2703503966331482},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.21201813220977783},{"id":"https://openalex.org/C6557445","wikidata":"https://www.wikidata.org/wiki/Q173113","display_name":"Agronomy","level":1,"score":0.1943088173866272}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.1089/biores.2020.0013","doi":"https://doi.org/10.1089/biores.2020.0013","is_oa":true,"landing_page_url":"https://doi.org/10.1089/biores.2020.0013","pdf_url":"https://www.liebertpub.com/doi/pdf/10.1089/biores.2020.0013","source":{"id":"https://openalex.org/S4210180731","display_name":"BioResearch open access","issn_l":"2164-7844","issn":["2164-7844","2164-7860"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1","ki-jl-1","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320443","host_organization_name":"Mary Ann Liebert, Inc.","host_organization_lineage":["https://openalex.org/P4310320443","https://openalex.org/P4310320017"],"host_organization_lineage_names":["Mary Ann Liebert, Inc.","SAGE Publishing"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BioResearch Open Access","raw_type":"journal-article"},{"id":"pmid:32923174","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/32923174","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BioResearch open access","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:7484892","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC7484892/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biores Open Access","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1089/biores.2020.0013","doi":"https://doi.org/10.1089/biores.2020.0013","is_oa":true,"landing_page_url":"https://doi.org/10.1089/biores.2020.0013","pdf_url":"https://www.liebertpub.com/doi/pdf/10.1089/biores.2020.0013","source":{"id":"https://openalex.org/S4210180731","display_name":"BioResearch open access","issn_l":"2164-7844","issn":["2164-7844","2164-7860"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1","ki-jl-1","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320443","host_organization_name":"Mary Ann Liebert, Inc.","host_organization_lineage":["https://openalex.org/P4310320443","https://openalex.org/P4310320017"],"host_organization_lineage_names":["Mary Ann Liebert, Inc.","SAGE Publishing"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BioResearch Open Access","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.8409000039100647,"id":"https://metadata.un.org/sdg/2","display_name":"Zero hunger"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3081964482.pdf","grobid_xml":"https://content.openalex.org/works/W3081964482.grobid-xml"},"referenced_works_count":43,"referenced_works":["https://openalex.org/W315745794","https://openalex.org/W1562432999","https://openalex.org/W1802427789","https://openalex.org/W1955434848","https://openalex.org/W1978209747","https://openalex.org/W1980979241","https://openalex.org/W1991979961","https://openalex.org/W1997272327","https://openalex.org/W2007482003","https://openalex.org/W2012908995","https://openalex.org/W2018118114","https://openalex.org/W2018289835","https://openalex.org/W2019062831","https://openalex.org/W2025542995","https://openalex.org/W2030621075","https://openalex.org/W2040596538","https://openalex.org/W2049878839","https://openalex.org/W2050726288","https://openalex.org/W2083588901","https://openalex.org/W2084269026","https://openalex.org/W2090320674","https://openalex.org/W2099836913","https://openalex.org/W2100837269","https://openalex.org/W2111811286","https://openalex.org/W2113624915","https://openalex.org/W2114872930","https://openalex.org/W2128635872","https://openalex.org/W2170616617","https://openalex.org/W2176843124","https://openalex.org/W2190647981","https://openalex.org/W2192648207","https://openalex.org/W2406523124","https://openalex.org/W2612749424","https://openalex.org/W2738526643","https://openalex.org/W2762594265","https://openalex.org/W2775561802","https://openalex.org/W2776899289","https://openalex.org/W2796531554","https://openalex.org/W2884037854","https://openalex.org/W2904390024","https://openalex.org/W2928405625","https://openalex.org/W2964990826","https://openalex.org/W2989775272"],"related_works":["https://openalex.org/W4378212008","https://openalex.org/W2563146947","https://openalex.org/W2981902588","https://openalex.org/W2406523124","https://openalex.org/W7037826627","https://openalex.org/W6980546763","https://openalex.org/W2099836913","https://openalex.org/W2960638365","https://openalex.org/W4399975582","https://openalex.org/W438472908"],"abstract_inverted_index":{"The":[0,40],"interest":[1],"in":[2,37,65,183],"extracting":[3],"kafirins":[4],"(KAF),":[5],"the":[6,22,27,31,45,57,62,66,75,107,184],"main":[7],"storage":[8],"protein":[9,91],"from":[10,34,96,115],"sorghum":[11,117],"grain":[12],"has":[13],"recently":[14],"increased":[15,74],"due":[16],"to":[17,43,55],"its":[18],"gluten-free":[19],"content":[20],"and":[21,60,87,99,131,137,139,191],"significant":[23],"scientific":[24],"evidence":[25],"showing":[26],"health":[28],"benefits":[29],"of":[30,48,78,124,152],"bioactive":[32,63,104,153],"peptides":[33,64,133,154,158],"cereal":[35],"grains":[36],"human":[38],"diets.":[39],"objectives":[41],"were":[42,94,100,173],"obtain":[44],"highest":[46],"percentage":[47],"KAF":[49,79,97,113,148,179],"extraction":[50,58,76,82],"using":[51,84,106,145],"amyloglucosidase":[52,73],"as":[53,121],"pretreatment":[54],"increase":[56],"yield":[59,77],"predict":[61],"KAF.":[67],"In":[68,162],"this":[69],"study,":[70],"pretreatments":[71],"with":[72,81,155,187],"compared":[80],"methods":[83],"only":[85],"ethanol":[86],"sodium":[88],"metabisulfite.":[89],"Two":[90],"fragment":[92],"sequences":[93,167],"identified":[95],"extract":[98],"evaluated":[101],"for":[102],"potential":[103,150,188],"peptide":[105,166,185],"BIOPEP-UWM":[108],"database,":[109],"which":[110],"suggest":[111,177],"that":[112,168,178],"proteins":[114],"white":[116],"may":[118],"be":[119,181],"considered":[120],"good":[122],"precursors":[123],"dipeptidyl":[125],"peptidase-inhibitor,":[126],"angiotensin-converting":[127],"enzyme":[128],"inhibitor,":[129],"antioxidant":[130],"hypotensive":[132],"following":[134],"chymotrypsin,":[135],"thermolysin,":[136],"subtilisin":[138],"their":[140],"combination.":[141],"Average":[142],"scores":[143],"aligned":[144],"PeptideRanker":[146],"confirmed":[147],"proteins'":[149],"sources":[151],"over":[156,160],"5":[157],"scored":[159],"0.8.":[161],"addition,":[163],"31":[164],"unexplored":[165],"could":[169],"have":[170],"biological":[171,189],"activity":[172,190],"identified.":[174],"Our":[175],"results":[176],"can":[180],"used":[182],"productions":[186],"beyond.":[192]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":5},{"year":2024,"cited_by_count":10},{"year":2023,"cited_by_count":7},{"year":2022,"cited_by_count":9},{"year":2021,"cited_by_count":5}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2020-09-08T00:00:00"}