{"id":"https://openalex.org/W3081784613","doi":null,"title":"AKT/IKK\u03b1/VAV1 signaling in endothelial cell survival and angiogenesis","display_name":"AKT/IKK\u03b1/VAV1 signaling in endothelial cell survival and angiogenesis","publication_year":2008,"publication_date":"2008-04-28","ids":{"openalex":"https://openalex.org/W3081784613","mag":"3081784613"},"language":"en","primary_location":{"id":"mag:3081784613","doi":null,"is_oa":false,"landing_page_url":"https://ir.vanderbilt.edu/handle/1803/11831","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5062829401","display_name":"Laura M. DeBusk","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Laura M. DeBusk","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5062829401"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10422","display_name":"Angiogenesis and VEGF in Cancer","score":0.9535999894142151,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10422","display_name":"Angiogenesis and VEGF in Cancer","score":0.9535999894142151,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10169","display_name":"Protein Kinase Regulation and GTPase Signaling","score":0.01679999940097332,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10952","display_name":"PI3K/AKT/mTOR signaling in cancer","score":0.010599999688565731,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/akt-signaling","display_name":"Akt signaling","score":0.9679999947547913},{"id":"https://openalex.org/keywords/ikkalpha","display_name":"IKK\u03b1","score":0.9300000071525574},{"id":"https://openalex.org/keywords/vav1","display_name":"Vav1","score":0.9929999709129333},{"id":"https://openalex.org/keywords/endothelial-cell-survival","display_name":"endothelial cell survival","score":0.9440000057220459},{"id":"https://openalex.org/keywords/angiogenesis","display_name":"angiogenesis","score":0.9829999804496765},{"id":"https://openalex.org/keywords/endothelial-cells","display_name":"endothelial cells","score":0.5529999732971191},{"id":"https://openalex.org/keywords/pi3k-akt-signaling","display_name":"PI3K/Akt signaling","score":0.7300000190734863},{"id":"https://openalex.org/keywords/nf-kappab-signaling","display_name":"NF-\u03baB signaling","score":0.7910000085830688}],"concepts":[{"id":"https://openalex.org/C2780394083","wikidata":"https://www.wikidata.org/wiki/Q539568","display_name":"Angiogenesis","level":2,"score":0.7477789521217346},{"id":"https://openalex.org/C75217442","wikidata":"https://www.wikidata.org/wiki/Q423650","display_name":"Protein kinase B","level":3,"score":0.6173716187477112},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.4577062129974365},{"id":"https://openalex.org/C86554907","wikidata":"https://www.wikidata.org/wiki/Q285613","display_name":"PI3K/AKT/mTOR pathway","level":3,"score":0.42102473974227905},{"id":"https://openalex.org/C62478195","wikidata":"https://www.wikidata.org/wiki/Q828130","display_name":"Signal transduction","level":2,"score":0.4012237787246704},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.38119393587112427},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.27318811416625977},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.23745644092559814}],"mesh":[],"locations_count":1,"locations":[{"id":"mag:3081784613","doi":null,"is_oa":false,"landing_page_url":"https://ir.vanderbilt.edu/handle/1803/11831","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.4426000118255615,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":116,"referenced_works":["https://openalex.org/W12577210","https://openalex.org/W131062528","https://openalex.org/W135518686","https://openalex.org/W183134926","https://openalex.org/W1485363052","https://openalex.org/W1501881225","https://openalex.org/W1507541276","https://openalex.org/W1537398036","https://openalex.org/W1581923494","https://openalex.org/W1587286343","https://openalex.org/W1603973043","https://openalex.org/W1670312687","https://openalex.org/W1783580437","https://openalex.org/W1818326785","https://openalex.org/W1880356166","https://openalex.org/W1939369424","https://openalex.org/W1964948989","https://openalex.org/W1965950604","https://openalex.org/W1966052610","https://openalex.org/W1969230145","https://openalex.org/W1969937534","https://openalex.org/W1970614272","https://openalex.org/W1973262582","https://openalex.org/W1973803951","https://openalex.org/W1973890143","https://openalex.org/W1974499183","https://openalex.org/W1976443579","https://openalex.org/W1980415233","https://openalex.org/W1980969801","https://openalex.org/W1981115336","https://openalex.org/W1982776595","https://openalex.org/W1985850927","https://openalex.org/W1985871447","https://openalex.org/W1990112424","https://openalex.org/W1990201193","https://openalex.org/W1991463736","https://openalex.org/W1992623236","https://openalex.org/W1993836723","https://openalex.org/W1996430165","https://openalex.org/W1996526210","https://openalex.org/W1997620405","https://openalex.org/W1999692789","https://openalex.org/W1999771190","https://openalex.org/W2001271989","https://openalex.org/W2002066494","https://openalex.org/W2002934423","https://openalex.org/W2003408160","https://openalex.org/W2004280666","https://openalex.org/W2006444511","https://openalex.org/W2012831646","https://openalex.org/W2016000024","https://openalex.org/W2017041417","https://openalex.org/W2019351392","https://openalex.org/W2021268612","https://openalex.org/W2021685959","https://openalex.org/W2028466368","https://openalex.org/W2035029345","https://openalex.org/W2040210675","https://openalex.org/W2044356299","https://openalex.org/W2054919355","https://openalex.org/W2054957750","https://openalex.org/W2055206081","https://openalex.org/W2056920813","https://openalex.org/W2059041221","https://openalex.org/W2062757092","https://openalex.org/W2064686935","https://openalex.org/W2066888615","https://openalex.org/W2067796529","https://openalex.org/W2068499444","https://openalex.org/W2070966344","https://openalex.org/W2073738021","https://openalex.org/W2074291164","https://openalex.org/W2075073585","https://openalex.org/W2077078276","https://openalex.org/W2078348571","https://openalex.org/W2080100938","https://openalex.org/W2083462984","https://openalex.org/W2087313947","https://openalex.org/W2088782807","https://openalex.org/W2090839493","https://openalex.org/W2093715533","https://openalex.org/W2097466570","https://openalex.org/W2102237554","https://openalex.org/W2104069123","https://openalex.org/W2112528220","https://openalex.org/W2113951321","https://openalex.org/W2115207474","https://openalex.org/W2116393970","https://openalex.org/W2120026123","https://openalex.org/W2120555366","https://openalex.org/W2120797568","https://openalex.org/W2133353385","https://openalex.org/W2134384575","https://openalex.org/W2136480937","https://openalex.org/W2140459348","https://openalex.org/W2141290206","https://openalex.org/W2147748309","https://openalex.org/W2148953261","https://openalex.org/W2149092068","https://openalex.org/W2151868383","https://openalex.org/W2152215024","https://openalex.org/W2152505099","https://openalex.org/W2153841452","https://openalex.org/W2157941198","https://openalex.org/W2158334675","https://openalex.org/W2159868799","https://openalex.org/W2164910039","https://openalex.org/W2166781237","https://openalex.org/W2170773649","https://openalex.org/W2171354819","https://openalex.org/W2290322450","https://openalex.org/W2315613727","https://openalex.org/W2316580498","https://openalex.org/W2330980944","https://openalex.org/W2396486584","https://openalex.org/W4313379449"],"related_works":["https://openalex.org/W2281629675","https://openalex.org/W1973262582","https://openalex.org/W7097180948","https://openalex.org/W2323758287","https://openalex.org/W2112547972","https://openalex.org/W2168438265","https://openalex.org/W2125861553","https://openalex.org/W4238227476","https://openalex.org/W1980969801","https://openalex.org/W1985850927"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2020-09-08T00:00:00"}