{"id":"https://openalex.org/W3081277989","doi":"https://doi.org/10.1007/978-1-0716-0644-5_22","title":"Investigation of Break-Induced Replication in Yeast","display_name":"Investigation of Break-Induced Replication in Yeast","publication_year":2020,"publication_date":"2020-08-25","ids":{"openalex":"https://openalex.org/W3081277989","doi":"https://doi.org/10.1007/978-1-0716-0644-5_22","mag":"3081277989","pmid":"https://pubmed.ncbi.nlm.nih.gov/32840789","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/9041317"},"language":"en","primary_location":{"id":"doi:10.1007/978-1-0716-0644-5_22","doi":"https://doi.org/10.1007/978-1-0716-0644-5_22","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-1-0716-0644-5_22","pdf_url":null,"source":{"id":"https://openalex.org/S4210172139","display_name":"Methods in molecular biology","issn_l":"1064-3745","issn":["1064-3745","1940-6029"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-3","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Methods in Molecular Biology","raw_type":"book-chapter"},"volume":{"id":"https://openalex.org/W3128995283","display_name":"Homologous Recombination"},"type":"book-chapter","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/9041317","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5033069001","display_name":"Beth Osia","orcid":"https://orcid.org/0000-0002-2848-5367","observed_orcids":["https://orcid.org/0000-0002-2848-5367"]},"institutions":[{"id":"https://openalex.org/I126307644","display_name":"University of Iowa","ror":"https://ror.org/036jqmy94","country_code":"US","type":"education","lineage":["https://openalex.org/I126307644"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Beth Osia","raw_affiliation_strings":["Department of Biology, University of Iowa, Iowa City, IA, USA","Department of Biology, University of Iowa, Iowa City, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biology, University of Iowa, Iowa City, IA, USA","institution_ids":["https://openalex.org/I126307644"]},{"raw_affiliation_string":"Department of Biology, University of Iowa, Iowa City, USA","institution_ids":["https://openalex.org/I126307644"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048379856","display_name":"Rajula Elango","orcid":"https://orcid.org/0000-0001-7282-623X","observed_orcids":["https://orcid.org/0000-0001-7282-623X"]},"institutions":[{"id":"https://openalex.org/I1316535847","display_name":"Beth Israel Deaconess Medical Center","ror":"https://ror.org/04drvxt59","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1316535847"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Rajula Elango","raw_affiliation_strings":["Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA","Department of Medicine, Division of Hematology-Oncology, Cancer Research Institute, Harvard Medical School, Boston, MA, USA","Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, USA","Department of Medicine, Division of Hematology-Oncology, Cancer Research Institute, Harvard Medical School, Boston, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA","institution_ids":["https://openalex.org/I1316535847","https://openalex.org/I136199984"]},{"raw_affiliation_string":"Department of Medicine, Division of Hematology-Oncology, Cancer Research Institute, Harvard Medical School, Boston, MA, USA","institution_ids":["https://openalex.org/I136199984"]},{"raw_affiliation_string":"Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, USA","institution_ids":["https://openalex.org/I1316535847","https://openalex.org/I136199984"]},{"raw_affiliation_string":"Department of Medicine, Division of Hematology-Oncology, Cancer Research Institute, Harvard Medical School, Boston, USA","institution_ids":["https://openalex.org/I136199984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5088415364","display_name":"Juraj Kramara","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I126307644","display_name":"University of Iowa","ror":"https://ror.org/036jqmy94","country_code":"US","type":"education","lineage":["https://openalex.org/I126307644"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Juraj Kramara","raw_affiliation_strings":["Department of Biology, University of Iowa, Iowa City, IA, USA","Department of Biology, University of Iowa, Iowa City, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biology, University of Iowa, Iowa City, IA, USA","institution_ids":["https://openalex.org/I126307644"]},{"raw_affiliation_string":"Department of Biology, University of Iowa, Iowa City, USA","institution_ids":["https://openalex.org/I126307644"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045510214","display_name":"Steven A. Roberts","orcid":"https://orcid.org/0000-0002-3628-5808","observed_orcids":["https://orcid.org/0000-0002-3628-5808"]},"institutions":[{"id":"https://openalex.org/I72951846","display_name":"Washington State University","ror":"https://ror.org/05dk0ce17","country_code":"US","type":"education","lineage":["https://openalex.org/I72951846"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Steven A. Roberts","raw_affiliation_strings":["School of Molecular Biosciences, Center for Reproductive Biology, Washington State University, Pullman, WA, USA","School of Molecular Biosciences, Center for Reproductive Biology, Washington State University, Pullman, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Molecular Biosciences, Center for Reproductive Biology, Washington State University, Pullman, WA, USA","institution_ids":["https://openalex.org/I72951846"]},{"raw_affiliation_string":"School of Molecular Biosciences, Center for Reproductive Biology, Washington State University, Pullman, USA","institution_ids":["https://openalex.org/I72951846"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5070502223","display_name":"Anna Malkova","orcid":"https://orcid.org/0000-0002-3880-1781","observed_orcids":["https://orcid.org/0000-0002-3880-1781"]},"institutions":[{"id":"https://openalex.org/I126307644","display_name":"University of Iowa","ror":"https://ror.org/036jqmy94","country_code":"US","type":"education","lineage":["https://openalex.org/I126307644"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Anna Malkova","raw_affiliation_strings":["Department of Biology, University of Iowa, Iowa City, IA, USA. anna-malkova@uiowa.edu","Department of Biology, University of Iowa, Iowa City, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biology, University of Iowa, Iowa City, IA, USA. anna-malkova@uiowa.edu","institution_ids":["https://openalex.org/I126307644"]},{"raw_affiliation_string":"Department of Biology, University of Iowa, Iowa City, USA","institution_ids":["https://openalex.org/I126307644"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5070502223"],"corresponding_institution_ids":["https://openalex.org/I126307644"],"apc_list":null,"apc_paid":null,"fwci":0.6754,"has_fulltext":false,"cited_by_count":2,"citation_normalized_percentile":{"value":0.70589598,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":"2153","issue":null,"first_page":"307","last_page":"328"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10123","display_name":"DNA Repair Mechanisms","score":0.9970999956130981,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10123","display_name":"DNA Repair Mechanisms","score":0.9970999956130981,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10497","display_name":"Fungal and yeast genetics research","score":0.002099999925121665,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10120","display_name":"Bacterial Genetics and Biotechnology","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/break-induced-replication","display_name":"break-induced replication","score":1.0},{"id":"https://openalex.org/keywords/dna-double-strand-breaks","display_name":"DNA double-strand breaks","score":0.8320000171661377},{"id":"https://openalex.org/keywords/dna-repair","display_name":"DNA repair","score":0.7910000085830688},{"id":"https://openalex.org/keywords/saccharomyces-cerevisiae","display_name":"Saccharomyces cerevisiae","score":0.9409999847412109},{"id":"https://openalex.org/keywords/chromosome-iii","display_name":"chromosome III","score":0.6309999823570251},{"id":"https://openalex.org/keywords/mutagenesis","display_name":"mutagenesis","score":0.7829999923706055},{"id":"https://openalex.org/keywords/chromosomal-rearrangements","display_name":"chromosomal rearrangements","score":0.9909999966621399},{"id":"https://openalex.org/keywords/replication-fork-collapse","display_name":"replication fork collapse","score":0.8180000185966492},{"id":"https://openalex.org/keywords/telomere-shortening","display_name":"telomere shortening","score":0.9229999780654907},{"id":"https://openalex.org/keywords/dna-bubbles","display_name":"DNA bubbles","score":0.33899998664855957}],"concepts":[{"id":"https://openalex.org/C73573662","wikidata":"https://www.wikidata.org/wiki/Q130996","display_name":"DNA replication","level":3,"score":0.6020245552062988},{"id":"https://openalex.org/C13052165","wikidata":"https://www.wikidata.org/wiki/Q1208348","display_name":"Semiconservative replication","level":5,"score":0.5984941720962524},{"id":"https://openalex.org/C104690221","wikidata":"https://www.wikidata.org/wiki/Q5165872","display_name":"Control of chromosome duplication","level":4,"score":0.5696291327476501},{"id":"https://openalex.org/C98086919","wikidata":"https://www.wikidata.org/wiki/Q118019","display_name":"Eukaryotic DNA replication","level":4,"score":0.5583271980285645},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5554060339927673},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.5142109394073486},{"id":"https://openalex.org/C113271649","wikidata":"https://www.wikidata.org/wiki/Q2565234","display_name":"Replication protein A","level":5,"score":0.4486258327960968},{"id":"https://openalex.org/C552990157","wikidata":"https://www.wikidata.org/wiki/Q7430","display_name":"DNA","level":2,"score":0.44640278816223145},{"id":"https://openalex.org/C134935766","wikidata":"https://www.wikidata.org/wiki/Q210538","display_name":"DNA repair","level":3,"score":0.4243048429489136},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.2739272713661194},{"id":"https://openalex.org/C94966510","wikidata":"https://www.wikidata.org/wiki/Q2252764","display_name":"DNA-binding protein","level":4,"score":0.0863804817199707},{"id":"https://openalex.org/C86339819","wikidata":"https://www.wikidata.org/wiki/Q407384","display_name":"Transcription factor","level":3,"score":0.0}],"mesh":[{"descriptor_ui":"D003564","descriptor_name":"Cytidine Deaminase","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D004261","descriptor_name":"DNA Replication","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009154","descriptor_name":"Mutation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012441","descriptor_name":"Saccharomyces cerevisiae","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D012441","descriptor_name":"Saccharomyces cerevisiae","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D015825","descriptor_name":"Chromosomes, Fungal","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D029701","descriptor_name":"Saccharomyces cerevisiae Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D053903","descriptor_name":"DNA Breaks, Double-Stranded","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D059767","descriptor_name":"Recombinational DNA Repair","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1007/978-1-0716-0644-5_22","doi":"https://doi.org/10.1007/978-1-0716-0644-5_22","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-1-0716-0644-5_22","pdf_url":null,"source":{"id":"https://openalex.org/S4210172139","display_name":"Methods in molecular biology","issn_l":"1064-3745","issn":["1064-3745","1940-6029"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-3","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Methods in Molecular Biology","raw_type":"book-chapter"},{"id":"pmid:32840789","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/32840789","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Methods in molecular biology (Clifton, N.J.)","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:9041317","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/9041317","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Methods Mol Biol","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:9041317","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/9041317","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Methods Mol Biol","raw_type":"Text"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G3590858668","display_name":"Identifying the link between the mode of telomere erosion and alternative telomere lengthening","funder_award_id":"R21ES030307","funder_id":"https://openalex.org/F4320337361","funder_display_name":"National Institute of Environmental Health Sciences"},{"id":"https://openalex.org/G6299212903","display_name":"Suppressors and drivers of long-tract repair DNA synthesis","funder_award_id":"R03ES029306","funder_id":"https://openalex.org/F4320337361","funder_display_name":"National Institute of Environmental Health Sciences"},{"id":"https://openalex.org/G6472164503","display_name":"Mechanisms of genome instability induced by APOBEC Cytidine Deaminases and its impacts during cancer development.","funder_award_id":"R01CA218112","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G9000872274","display_name":"Double strand break repair maelstrom: causes, mechanisms and genome destabilizing consequences","funder_award_id":"R35GM127006","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"}],"funders":[{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"},{"id":"https://openalex.org/F4320337354","display_name":"National Institute of General Medical Sciences","ror":"https://ror.org/04q48ey07"},{"id":"https://openalex.org/F4320337361","display_name":"National Institute of Environmental Health Sciences","ror":"https://ror.org/00j4k1h63"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":23,"referenced_works":["https://openalex.org/W1758844431","https://openalex.org/W1964831588","https://openalex.org/W1968493165","https://openalex.org/W2008202253","https://openalex.org/W2009825306","https://openalex.org/W2023218302","https://openalex.org/W2054560592","https://openalex.org/W2059885034","https://openalex.org/W2069839388","https://openalex.org/W2075478564","https://openalex.org/W2077570881","https://openalex.org/W2113908436","https://openalex.org/W2118393957","https://openalex.org/W2144171940","https://openalex.org/W2156466607","https://openalex.org/W2157434667","https://openalex.org/W2183570771","https://openalex.org/W2204392137","https://openalex.org/W2542991120","https://openalex.org/W2576734941","https://openalex.org/W2592429281","https://openalex.org/W2770813668","https://openalex.org/W2968790862"],"related_works":["https://openalex.org/W3140971027","https://openalex.org/W2241329457","https://openalex.org/W2607210226","https://openalex.org/W2800503833","https://openalex.org/W3198522767","https://openalex.org/W4224293229","https://openalex.org/W2552473602","https://openalex.org/W1530612520","https://openalex.org/W6964393315","https://openalex.org/W593865354"],"abstract_inverted_index":null,"counts_by_year":[{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2020-09-01T00:00:00"}