{"id":"https://openalex.org/W3080911853","doi":"https://doi.org/10.1007/s11882-020-00964-y","title":"The Child with Elevated IgE and Infection Susceptibility","display_name":"The Child with Elevated IgE and Infection Susceptibility","publication_year":2020,"publication_date":"2020-08-24","ids":{"openalex":"https://openalex.org/W3080911853","doi":"https://doi.org/10.1007/s11882-020-00964-y","mag":"3080911853","pmid":"https://pubmed.ncbi.nlm.nih.gov/32830295"},"language":"en","primary_location":{"id":"doi:10.1007/s11882-020-00964-y","doi":"https://doi.org/10.1007/s11882-020-00964-y","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s11882-020-00964-y","pdf_url":null,"source":{"id":"https://openalex.org/S10734860","display_name":"Current Allergy and Asthma Reports","issn_l":"1529-7322","issn":["1529-7322","1534-6315"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Current Allergy and Asthma Reports","raw_type":"journal-article"},"volume":null,"type":"review","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5063867007","display_name":"Alexandra F. Freeman","orcid":"https://orcid.org/0000-0001-7005-8345","observed_orcids":["https://orcid.org/0000-0001-7005-8345"]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210134534","display_name":"National Institute of Allergy and Infectious Diseases","ror":"https://ror.org/043z4tv69","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210134534"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Alexandra F. Freeman","raw_affiliation_strings":["National Institute of Allergy and Infectious Diseases, National Institutes of Health, NIH Building 10 Room 12C103, 9000 Rockville Pike, Bethesda, MD, 20892, USA. freemaal@mail.nih.gov","National Institute of Allergy and Infectious Diseases, National Institutes of Health, NIH Building 10 Room 12C103, 9000 Rockville Pike, Bethesda, MD, 20892, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"National Institute of Allergy and Infectious Diseases, National Institutes of Health, NIH Building 10 Room 12C103, 9000 Rockville Pike, Bethesda, MD, 20892, USA. freemaal@mail.nih.gov","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210134534"]},{"raw_affiliation_string":"National Institute of Allergy and Infectious Diseases, National Institutes of Health, NIH Building 10 Room 12C103, 9000 Rockville Pike, Bethesda, MD, 20892, USA","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210134534"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5002507553","display_name":"Joshua D. Milner","orcid":"https://orcid.org/0000-0002-3913-3869","observed_orcids":["https://orcid.org/0000-0002-3913-3869"]},"institutions":[{"id":"https://openalex.org/I1294429298","display_name":"Morgan Stanley Children's Hospital","ror":"https://ror.org/016m8pd54","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1294429298","https://openalex.org/I1340179700"]},{"id":"https://openalex.org/I2799503643","display_name":"Columbia University Irving Medical Center","ror":"https://ror.org/01esghr10","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799503643"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Joshua D. Milner","raw_affiliation_strings":["Division of Allergy, Immunology and Rheumatology, Columbia University Medical Center, New York-Presbyterian Morgan Stanley Children's Hospital, New York, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Allergy, Immunology and Rheumatology, Columbia University Medical Center, New York-Presbyterian Morgan Stanley Children's Hospital, New York, NY, USA","institution_ids":["https://openalex.org/I1294429298","https://openalex.org/I2799503643"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5063867007"],"corresponding_institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210134534"],"apc_list":{"value":3860,"currency":"USD","value_usd":3860},"apc_paid":null,"fwci":0.2489,"has_fulltext":false,"cited_by_count":15,"citation_normalized_percentile":{"value":0.24037855,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":93,"max":97},"biblio":{"volume":"20","issue":"11","first_page":"65","last_page":"65"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11725","display_name":"Immunodeficiency and Autoimmune Disorders","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11725","display_name":"Immunodeficiency and Autoimmune Disorders","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10031","display_name":"T-cell and B-cell Immunology","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10051","display_name":"Asthma and respiratory diseases","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/elevated-ige","display_name":"elevated IgE","score":0.8690000176429749},{"id":"https://openalex.org/keywords/infection-susceptibility","display_name":"infection susceptibility","score":0.9459999799728394},{"id":"https://openalex.org/keywords/stat3-deficiency","display_name":"STAT3 deficiency","score":0.703000009059906},{"id":"https://openalex.org/keywords/dock8-deficiency","display_name":"DOCK8 deficiency","score":0.9890000224113464},{"id":"https://openalex.org/keywords/dock8","display_name":"DOCK8","score":0.7089999914169312},{"id":"https://openalex.org/keywords/monogenic-immunodeficiency","display_name":"monogenic immunodeficiency","score":0.6629999876022339},{"id":"https://openalex.org/keywords/allergy","display_name":"allergy","score":0.4740000069141388},{"id":"https://openalex.org/keywords/atopic-dermatitis","display_name":"atopic dermatitis","score":0.9900000095367432},{"id":"https://openalex.org/keywords/scoliosis","display_name":"scoliosis","score":0.796999990940094},{"id":"https://openalex.org/keywords/aneurysm","display_name":"aneurysm","score":0.8939999938011169},{"id":"https://openalex.org/keywords/virus-susceptibility","display_name":"viral susceptibility","score":0.7319999933242798}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6004661321640015},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.592125415802002},{"id":"https://openalex.org/C127716648","wikidata":"https://www.wikidata.org/wiki/Q104053","display_name":"Phenotype","level":3,"score":0.5892910361289978},{"id":"https://openalex.org/C207480886","wikidata":"https://www.wikidata.org/wiki/Q42982","display_name":"Allergy","level":2,"score":0.5705748200416565},{"id":"https://openalex.org/C137627325","wikidata":"https://www.wikidata.org/wiki/Q156318","display_name":"Etiology","level":2,"score":0.4759273827075958},{"id":"https://openalex.org/C67636389","wikidata":"https://www.wikidata.org/wiki/Q784237","display_name":"Genetic predisposition","level":3,"score":0.4756823778152466},{"id":"https://openalex.org/C141105273","wikidata":"https://www.wikidata.org/wiki/Q79455","display_name":"Immunoglobulin E","level":3,"score":0.47001126408576965},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.46402719616889954},{"id":"https://openalex.org/C90420996","wikidata":"https://www.wikidata.org/wiki/Q15324120","display_name":"TRPV4","level":4,"score":0.43194055557250977},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.30332276225090027},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.21388471126556396},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.1766851842403412},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.14490950107574463},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.1161869466304779},{"id":"https://openalex.org/C50254741","wikidata":"https://www.wikidata.org/wiki/Q62536","display_name":"Ion channel","level":3,"score":0.0},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D002648","descriptor_name":"Child","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004198","descriptor_name":"Disease Susceptibility","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007073","descriptor_name":"Immunoglobulin E","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D007073","descriptor_name":"Immunoglobulin E","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D007239","descriptor_name":"Infections","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1007/s11882-020-00964-y","doi":"https://doi.org/10.1007/s11882-020-00964-y","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s11882-020-00964-y","pdf_url":null,"source":{"id":"https://openalex.org/S10734860","display_name":"Current Allergy and Asthma Reports","issn_l":"1529-7322","issn":["1529-7322","1534-6315"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Current Allergy and Asthma Reports","raw_type":"journal-article"},{"id":"pmid:32830295","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/32830295","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Current allergy and asthma reports","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9537000060081482,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":67,"referenced_works":["https://openalex.org/W1154579084","https://openalex.org/W1588637297","https://openalex.org/W1907132844","https://openalex.org/W1931748660","https://openalex.org/W1974475548","https://openalex.org/W1982944254","https://openalex.org/W1983670187","https://openalex.org/W1984747726","https://openalex.org/W1992443284","https://openalex.org/W1995614807","https://openalex.org/W1996388035","https://openalex.org/W1997763572","https://openalex.org/W1999785838","https://openalex.org/W2007104787","https://openalex.org/W2055234427","https://openalex.org/W2061014664","https://openalex.org/W2061466699","https://openalex.org/W2065864330","https://openalex.org/W2070801985","https://openalex.org/W2072109427","https://openalex.org/W2074547696","https://openalex.org/W2076366279","https://openalex.org/W2080173245","https://openalex.org/W2081930860","https://openalex.org/W2084274092","https://openalex.org/W2096987586","https://openalex.org/W2097149586","https://openalex.org/W2099667165","https://openalex.org/W2102252678","https://openalex.org/W2104497596","https://openalex.org/W2121702910","https://openalex.org/W2125573161","https://openalex.org/W2140928868","https://openalex.org/W2142127956","https://openalex.org/W2158823847","https://openalex.org/W2162721157","https://openalex.org/W2164417002","https://openalex.org/W2167895056","https://openalex.org/W2170852908","https://openalex.org/W2171462887","https://openalex.org/W2216776703","https://openalex.org/W2289721368","https://openalex.org/W2329293925","https://openalex.org/W2340870558","https://openalex.org/W2413119699","https://openalex.org/W2532240069","https://openalex.org/W2560787367","https://openalex.org/W2577229000","https://openalex.org/W2581381928","https://openalex.org/W2618904922","https://openalex.org/W2720933772","https://openalex.org/W2740957219","https://openalex.org/W2743810071","https://openalex.org/W2808646259","https://openalex.org/W2884071753","https://openalex.org/W2888937895","https://openalex.org/W2889912337","https://openalex.org/W2897613262","https://openalex.org/W2898943853","https://openalex.org/W2904228660","https://openalex.org/W2912665543","https://openalex.org/W2914685386","https://openalex.org/W2921464694","https://openalex.org/W2937568612","https://openalex.org/W2954425631","https://openalex.org/W3012938891","https://openalex.org/W3023018592"],"related_works":["https://openalex.org/W2900967035","https://openalex.org/W2917142064","https://openalex.org/W7100037909","https://openalex.org/W3044172541","https://openalex.org/W2413119699","https://openalex.org/W3202018954","https://openalex.org/W4233533250","https://openalex.org/W4315488208","https://openalex.org/W3127882074","https://openalex.org/W2915030747"],"abstract_inverted_index":null,"counts_by_year":[{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":4},{"year":2022,"cited_by_count":4},{"year":2021,"cited_by_count":2}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2020-09-01T00:00:00"}