{"id":"https://openalex.org/W306274528","doi":"https://doi.org/10.1007/s00393-011-0887-2","title":"Personalisierte Medizin in der Auswahl konventioneller Immunsuppressiva und \u201edisease modifying anti-rheumatic drugs\u201c","display_name":"Personalisierte Medizin in der Auswahl konventioneller Immunsuppressiva und \u201edisease modifying anti-rheumatic drugs\u201c","publication_year":2012,"publication_date":"2012-12-17","ids":{"openalex":"https://openalex.org/W306274528","doi":"https://doi.org/10.1007/s00393-011-0887-2","mag":"306274528","pmid":"https://pubmed.ncbi.nlm.nih.gov/23247868"},"language":"de","primary_location":{"id":"doi:10.1007/s00393-011-0887-2","doi":"https://doi.org/10.1007/s00393-011-0887-2","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s00393-011-0887-2","pdf_url":null,"source":{"id":"https://openalex.org/S141282100","display_name":"Zeitschrift f\u00fcr Rheumatologie","issn_l":"0340-1855","issn":["0340-1855","1435-1250"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1","ki-jl-1","medline","norway-1","poland-40","russia-white-list-3"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Zeitschrift f\u00fcr Rheumatologie","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5035556769","display_name":"Christoph Fiehn","orcid":"https://orcid.org/0000-0001-9665-1526","observed_orcids":["https://orcid.org/0000-0001-9665-1526"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"C. Fiehn","raw_affiliation_strings":["ACURA-Rheumazentrum Baden-Baden, Baden-Baden","ACURA-Rheumazentrum Baden-Baden, Baden-Baden, Deutschland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"ACURA-Rheumazentrum Baden-Baden, Baden-Baden","institution_ids":[]},{"raw_affiliation_string":"ACURA-Rheumazentrum Baden-Baden, Baden-Baden, Deutschland","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029599938","display_name":"Gernot Key\u00dfer","orcid":"https://orcid.org/0000-0002-0058-286X","observed_orcids":["https://orcid.org/0000-0002-0058-286X"]},"institutions":[{"id":"https://openalex.org/I4210152429","display_name":"University Hospital in Halle","ror":"https://ror.org/04fe46645","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210152429"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"G. Key\u00dfer","raw_affiliation_strings":["Klinik und Poliklinik f\u00fcr Innere Medizin II, Universit\u00e4tsklinikum Halle (Saale), Halle (Saale), Deutschland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Klinik und Poliklinik f\u00fcr Innere Medizin II, Universit\u00e4tsklinikum Halle (Saale), Halle (Saale), Deutschland","institution_ids":["https://openalex.org/I4210152429"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5079831828","display_name":"Hanns\u2010Martin Lorenz","orcid":"https://orcid.org/0000-0001-8197-8681","observed_orcids":["https://orcid.org/0000-0001-8197-8681"]},"institutions":[{"id":"https://openalex.org/I223822909","display_name":"Heidelberg University","ror":"https://ror.org/038t36y30","country_code":"DE","type":"education","lineage":["https://openalex.org/I223822909"]},{"id":"https://openalex.org/I2802164966","display_name":"University Hospital Heidelberg","ror":"https://ror.org/013czdx64","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I2802164966"]}],"countries":["DE"],"is_corresponding":true,"raw_author_name":"H.-M. Lorenz","raw_affiliation_strings":["ACURA-Rheumazentrum Baden-Baden, Baden-Baden, Deutschland","Abteilung Innere Medizin V H\u00e4matologie, Onkologie, Rheumatologie, Medizinische Universit\u00e4tsklinik, Im Neuenheimer Feld 410, 69120, Heidelberg, Deutschland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"ACURA-Rheumazentrum Baden-Baden, Baden-Baden, Deutschland","institution_ids":[]},{"raw_affiliation_string":"Abteilung Innere Medizin V H\u00e4matologie, Onkologie, Rheumatologie, Medizinische Universit\u00e4tsklinik, Im Neuenheimer Feld 410, 69120, Heidelberg, Deutschland","institution_ids":["https://openalex.org/I223822909","https://openalex.org/I2802164966"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5079831828"],"corresponding_institution_ids":["https://openalex.org/I223822909","https://openalex.org/I2802164966"],"apc_list":{"value":3390,"currency":"USD","value_usd":3390},"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"72","issue":"1","first_page":"27","last_page":"40"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10200","display_name":"Rheumatoid Arthritis Research and Therapies","score":0.9814000129699707,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10200","display_name":"Rheumatoid Arthritis Research and Therapies","score":0.9814000129699707,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10308","display_name":"Systemic Lupus Erythematosus Research","score":0.0020000000949949026,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10373","display_name":"Renal Transplantation Outcomes and Treatments","score":0.0010000000474974513,"subfield":{"id":"https://openalex.org/subfields/2747","display_name":"Transplantation"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/personalized-medicine","display_name":"personalized medicine","score":0.9990000128746033},{"id":"https://openalex.org/keywords/disease-modifying-antirheumatic-drugs","display_name":"disease-modifying antirheumatic drugs","score":0.906000018119812},{"id":"https://openalex.org/keywords/immunosuppressive-drugs","display_name":"immunosuppressants","score":0.9010000228881836},{"id":"https://openalex.org/keywords/autoimmune-disease","display_name":"autoimmune disease","score":0.9340000152587891},{"id":"https://openalex.org/keywords/drug-selection","display_name":"drug selection","score":0.7670000195503235},{"id":"https://openalex.org/keywords/genetic-polymorphism","display_name":"genetic polymorphism","score":0.9300000071525574},{"id":"https://openalex.org/keywords/drug-tolerance","display_name":"drug tolerance","score":0.7599999904632568},{"id":"https://openalex.org/keywords/treatment-effectiveness","display_name":"treatment effectiveness","score":0.6349999904632568},{"id":"https://openalex.org/keywords/patient-preferences","display_name":"patient preferences","score":0.7049999833106995},{"id":"https://openalex.org/keywords/infection-risk","display_name":"infection risk","score":0.36000001430511475},{"id":"https://openalex.org/keywords/adverse-effects","display_name":"adverse effects","score":0.5199999809265137}],"concepts":[{"id":"https://openalex.org/C29456083","wikidata":"https://www.wikidata.org/wiki/Q1221899","display_name":"Gynecology","level":1,"score":0.8518952131271362},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7607466578483582}],"mesh":[{"descriptor_ui":"D003657","descriptor_name":"Decision Making","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007166","descriptor_name":"Immunosuppressive Agents","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true},{"descriptor_ui":"D012216","descriptor_name":"Rheumatic Diseases","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D012219","descriptor_name":"Rheumatology","qualifier_ui":"Q000639","qualifier_name":"trends","is_major_topic":true},{"descriptor_ui":"D018501","descriptor_name":"Antirheumatic Agents","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true},{"descriptor_ui":"D057285","descriptor_name":"Precision Medicine","qualifier_ui":"Q000639","qualifier_name":"trends","is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1007/s00393-011-0887-2","doi":"https://doi.org/10.1007/s00393-011-0887-2","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s00393-011-0887-2","pdf_url":null,"source":{"id":"https://openalex.org/S141282100","display_name":"Zeitschrift f\u00fcr Rheumatologie","issn_l":"0340-1855","issn":["0340-1855","1435-1250"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1","ki-jl-1","medline","norway-1","poland-40","russia-white-list-3"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Zeitschrift f\u00fcr Rheumatologie","raw_type":"journal-article"},{"id":"pmid:23247868","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/23247868","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Zeitschrift fur Rheumatologie","raw_type":"English Abstract"},{"id":"mag:2292630442","doi":null,"is_oa":false,"landing_page_url":"https://link.springer.com/article/10.1007/s00393-011-0887-2","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9476000070571899}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":55,"referenced_works":["https://openalex.org/W71011451","https://openalex.org/W80936362","https://openalex.org/W135499890","https://openalex.org/W226637424","https://openalex.org/W1595390153","https://openalex.org/W1771607455","https://openalex.org/W1912223278","https://openalex.org/W1965175314","https://openalex.org/W1967784397","https://openalex.org/W1974310136","https://openalex.org/W1979398789","https://openalex.org/W1983386659","https://openalex.org/W1983779362","https://openalex.org/W1996551669","https://openalex.org/W2004135257","https://openalex.org/W2004194066","https://openalex.org/W2009122831","https://openalex.org/W2016157833","https://openalex.org/W2016287743","https://openalex.org/W2026417656","https://openalex.org/W2029562600","https://openalex.org/W2037440997","https://openalex.org/W2058687235","https://openalex.org/W2061523691","https://openalex.org/W2063340779","https://openalex.org/W2065541718","https://openalex.org/W2071054988","https://openalex.org/W2082874877","https://openalex.org/W2084056567","https://openalex.org/W2088887888","https://openalex.org/W2100260684","https://openalex.org/W2101528090","https://openalex.org/W2102134607","https://openalex.org/W2104729127","https://openalex.org/W2105367456","https://openalex.org/W2113333814","https://openalex.org/W2115692269","https://openalex.org/W2126996887","https://openalex.org/W2132795660","https://openalex.org/W2135644975","https://openalex.org/W2136230007","https://openalex.org/W2138612272","https://openalex.org/W2144258326","https://openalex.org/W2147623386","https://openalex.org/W2149459259","https://openalex.org/W2154337274","https://openalex.org/W2155247236","https://openalex.org/W2156049013","https://openalex.org/W2156449368","https://openalex.org/W2157239580","https://openalex.org/W2171364167","https://openalex.org/W2171624524","https://openalex.org/W2316059854","https://openalex.org/W2438151218","https://openalex.org/W2607079988"],"related_works":["https://openalex.org/W4316591229","https://openalex.org/W7166818253","https://openalex.org/W2125183102","https://openalex.org/W4214868509","https://openalex.org/W2092258239","https://openalex.org/W2168250913","https://openalex.org/W2024651299","https://openalex.org/W2134096916","https://openalex.org/W2910103058","https://openalex.org/W3086138300"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}