{"id":"https://openalex.org/W30578491","doi":null,"title":"A Histochemical Analysis of Mitochondrial Abnormalities in the Type I Fibers of Human Posterior Cricoarytenoid Muscle","display_name":"A Histochemical Analysis of Mitochondrial Abnormalities in the Type I Fibers of Human Posterior Cricoarytenoid Muscle","publication_year":2004,"publication_date":"2004-12-21","ids":{"openalex":"https://openalex.org/W30578491","mag":"30578491"},"language":"en","primary_location":{"id":"pmh:oai:d-scholarship.pitt.edu:10415","doi":null,"is_oa":true,"landing_page_url":"https://d-scholarship.pitt.edu/10415/1/telliscm_etdPitt2004.pdf","pdf_url":"http://d-scholarship.pitt.edu/10415/1/telliscm_etdPitt2004.pdf","source":{"id":"https://openalex.org/S4306402372","display_name":"D-Scholarship@Pitt (University of Pittsburgh)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I170201317","host_organization_name":"University of Pittsburgh","host_organization_lineage":["https://openalex.org/I170201317"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"PeerReviewed"},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://d-scholarship.pitt.edu/10415/1/telliscm_etdPitt2004.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5083975212","display_name":"Cari M. Tellis","orcid":"https://orcid.org/0000-0001-6271-9780","observed_orcids":["https://orcid.org/0000-0001-6271-9780"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Cari M. Tellis","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5083975212"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":1,"citation_normalized_percentile":{"value":0.00188998,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10301","display_name":"Mitochondrial Function and Pathology","score":0.8812999725341797,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10301","display_name":"Mitochondrial Function and Pathology","score":0.8812999725341797,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10441","display_name":"Muscle Physiology and Disorders","score":0.09690000116825104,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10863","display_name":"Voice and Speech Disorders","score":0.009800000116229057,"subfield":{"id":"https://openalex.org/subfields/3616","display_name":"Speech and Hearing"},"field":{"id":"https://openalex.org/fields/36","display_name":"Health Professions"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/posterior-cricoarytenoid-muscle","display_name":"posterior cricoarytenoid muscle","score":0.9539999961853027},{"id":"https://openalex.org/keywords/type-i-muscle-fibres","display_name":"type I muscle fibers","score":0.9139999747276306},{"id":"https://openalex.org/keywords/mitochondrial-abnormalities","display_name":"mitochondrial abnormalities","score":0.7710000276565552},{"id":"https://openalex.org/keywords/cytochrome-c-oxidase-deficiency","display_name":"cytochrome c oxidase deficiency","score":0.9980000257492065},{"id":"https://openalex.org/keywords/succinate-dehydrogenase","display_name":"succinate dehydrogenase","score":0.9359999895095825},{"id":"https://openalex.org/keywords/reactive-oxygen-species","display_name":"reactive oxygen species","score":0.7200000286102295},{"id":"https://openalex.org/keywords/aging","display_name":"aging","score":0.5529999732971191},{"id":"https://openalex.org/keywords/cigarette-smoke-exposure","display_name":"cigarette smoke exposure","score":0.7480000257492065},{"id":"https://openalex.org/keywords/laryngeal-muscles","display_name":"laryngeal muscles","score":0.8479999899864197},{"id":"https://openalex.org/keywords/laryngectomy","display_name":"laryngectomy","score":0.6819999814033508},{"id":"https://openalex.org/keywords/muscle-fiber-type","display_name":"muscle fiber type","score":0.5360000133514404}],"concepts":[{"id":"https://openalex.org/C123249941","wikidata":"https://www.wikidata.org/wiki/Q306116","display_name":"Cytochrome c oxidase","level":3,"score":0.8236750364303589},{"id":"https://openalex.org/C2781330172","wikidata":"https://www.wikidata.org/wiki/Q412837","display_name":"Succinate dehydrogenase","level":3,"score":0.5661190152168274},{"id":"https://openalex.org/C2780768313","wikidata":"https://www.wikidata.org/wiki/Q408068","display_name":"Cytochrome","level":3,"score":0.5076862573623657},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.49241888523101807},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.47124630212783813},{"id":"https://openalex.org/C38485361","wikidata":"https://www.wikidata.org/wiki/Q576379","display_name":"Oxidase test","level":3,"score":0.446353554725647},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.38119056820869446},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.32294416427612305},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.29768407344818115},{"id":"https://openalex.org/C28859421","wikidata":"https://www.wikidata.org/wiki/Q39572","display_name":"Mitochondrion","level":2,"score":0.22572898864746094},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.16421973705291748},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.10166168212890625}],"mesh":[],"locations_count":2,"locations":[{"id":"pmh:oai:d-scholarship.pitt.edu:10415","doi":null,"is_oa":true,"landing_page_url":"https://d-scholarship.pitt.edu/10415/1/telliscm_etdPitt2004.pdf","pdf_url":"http://d-scholarship.pitt.edu/10415/1/telliscm_etdPitt2004.pdf","source":{"id":"https://openalex.org/S4306402372","display_name":"D-Scholarship@Pitt (University of Pittsburgh)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I170201317","host_organization_name":"University of Pittsburgh","host_organization_lineage":["https://openalex.org/I170201317"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"PeerReviewed"},{"id":"mag:30578491","doi":null,"is_oa":false,"landing_page_url":"http://d-scholarship.pitt.edu/10415/1/telliscm_etdPitt2004.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"pmh:oai:d-scholarship.pitt.edu:10415","doi":null,"is_oa":true,"landing_page_url":"https://d-scholarship.pitt.edu/10415/1/telliscm_etdPitt2004.pdf","pdf_url":"http://d-scholarship.pitt.edu/10415/1/telliscm_etdPitt2004.pdf","source":{"id":"https://openalex.org/S4306402372","display_name":"D-Scholarship@Pitt (University of Pittsburgh)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I170201317","host_organization_name":"University of Pittsburgh","host_organization_lineage":["https://openalex.org/I170201317"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"PeerReviewed"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9537000060081482}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W30578491.pdf","grobid_xml":"https://content.openalex.org/works/W30578491.grobid-xml"},"referenced_works_count":141,"referenced_works":["https://openalex.org/W408505","https://openalex.org/W184091955","https://openalex.org/W319698068","https://openalex.org/W642564552","https://openalex.org/W1481229588","https://openalex.org/W1484668578","https://openalex.org/W1523426892","https://openalex.org/W1561643114","https://openalex.org/W1567245406","https://openalex.org/W1572288887","https://openalex.org/W1588595461","https://openalex.org/W1749757312","https://openalex.org/W1870980090","https://openalex.org/W1965616172","https://openalex.org/W1966255333","https://openalex.org/W1966517070","https://openalex.org/W1968617835","https://openalex.org/W1968952472","https://openalex.org/W1972497882","https://openalex.org/W1973025283","https://openalex.org/W1974005306","https://openalex.org/W1974396693","https://openalex.org/W1974582967","https://openalex.org/W1982153589","https://openalex.org/W1984864995","https://openalex.org/W1986374977","https://openalex.org/W1987325894","https://openalex.org/W1987462314","https://openalex.org/W1993426052","https://openalex.org/W1996552139","https://openalex.org/W1998498679","https://openalex.org/W2001982568","https://openalex.org/W2002084991","https://openalex.org/W2005070668","https://openalex.org/W2007531447","https://openalex.org/W2009044819","https://openalex.org/W2013492520","https://openalex.org/W2014267913","https://openalex.org/W2015638974","https://openalex.org/W2015646451","https://openalex.org/W2016915880","https://openalex.org/W2018910193","https://openalex.org/W2019221851","https://openalex.org/W2019252461","https://openalex.org/W2021407576","https://openalex.org/W2023451412","https://openalex.org/W2024501751","https://openalex.org/W2025107360","https://openalex.org/W2027074484","https://openalex.org/W2030434933","https://openalex.org/W2031569153","https://openalex.org/W2031619656","https://openalex.org/W2031739912","https://openalex.org/W2033743648","https://openalex.org/W2033929531","https://openalex.org/W2034501539","https://openalex.org/W2035966581","https://openalex.org/W2038563802","https://openalex.org/W2039636742","https://openalex.org/W2040175583","https://openalex.org/W2042635193","https://openalex.org/W2044619452","https://openalex.org/W2045591858","https://openalex.org/W2045672376","https://openalex.org/W2050821204","https://openalex.org/W2053432607","https://openalex.org/W2056620406","https://openalex.org/W2057645411","https://openalex.org/W2058537437","https://openalex.org/W2062689936","https://openalex.org/W2063174591","https://openalex.org/W2063403408","https://openalex.org/W2065363098","https://openalex.org/W2066726174","https://openalex.org/W2066820922","https://openalex.org/W2067594063","https://openalex.org/W2068337326","https://openalex.org/W2075026875","https://openalex.org/W2075566081","https://openalex.org/W2075685752","https://openalex.org/W2075729132","https://openalex.org/W2078479092","https://openalex.org/W2078749255","https://openalex.org/W2079414980","https://openalex.org/W2079461623","https://openalex.org/W2083861740","https://openalex.org/W2084102216","https://openalex.org/W2086896876","https://openalex.org/W2088749854","https://openalex.org/W2089648789","https://openalex.org/W2090553616","https://openalex.org/W2091199047","https://openalex.org/W2092112039","https://openalex.org/W2094870244","https://openalex.org/W2095524892","https://openalex.org/W2098179189","https://openalex.org/W2099148164","https://openalex.org/W2104035605","https://openalex.org/W2104689152","https://openalex.org/W2109291482","https://openalex.org/W2110537381","https://openalex.org/W2111623033","https://openalex.org/W2113007696","https://openalex.org/W2113394488","https://openalex.org/W2113710155","https://openalex.org/W2115505412","https://openalex.org/W2116369194","https://openalex.org/W2119150168","https://openalex.org/W2129533522","https://openalex.org/W2132905212","https://openalex.org/W2140433979","https://openalex.org/W2140994672","https://openalex.org/W2142046597","https://openalex.org/W2147745178","https://openalex.org/W2149521998","https://openalex.org/W2151271025","https://openalex.org/W2152723951","https://openalex.org/W2155824945","https://openalex.org/W2158550575","https://openalex.org/W2162288115","https://openalex.org/W2167498165","https://openalex.org/W2171810710","https://openalex.org/W2176715668","https://openalex.org/W2236975777","https://openalex.org/W2257372505","https://openalex.org/W2287719822","https://openalex.org/W2317210331","https://openalex.org/W2324809329","https://openalex.org/W2325730256","https://openalex.org/W2328596111","https://openalex.org/W2329425391","https://openalex.org/W2332455917","https://openalex.org/W2334656304","https://openalex.org/W2398145559","https://openalex.org/W2412723965","https://openalex.org/W2438640010","https://openalex.org/W2461088787","https://openalex.org/W2963914350","https://openalex.org/W3021137566","https://openalex.org/W4297573836","https://openalex.org/W4407212001"],"related_works":["https://openalex.org/W2018873179","https://openalex.org/W2050303681","https://openalex.org/W2050821204","https://openalex.org/W2155130652","https://openalex.org/W2171716690","https://openalex.org/W7098046941","https://openalex.org/W2072048586","https://openalex.org/W2019224352","https://openalex.org/W2037896667","https://openalex.org/W2078478142"],"abstract_inverted_index":{"Mitochondrial":[0],"deficiencies":[1],"are":[2,38],"present":[3],"in":[4,160,178],"limb":[5],"skeletal":[6],"muscle":[7,65,115,182],"fibers":[8,54,96,124,147,169],"throughout":[9],"normal":[10],"aging":[11],"and":[12,31,62,82,183],"can":[13],"increase":[14,46],"with":[15,97,103,125,158,170,176],"accumulated":[16,189],"exposure":[17,190],"to":[18,41,89,108,135,187,191],"reactive":[19,25,192],"oxide":[20,26,193],"species.":[21],"Exogenous":[22],"sources":[23],"of":[24,49,59,93,121,142,166],"species":[27,194],"include":[28],"cigarette":[29],"smoke":[30],"other":[32],"environmental":[33],"toxins.":[34],"Intrinsic":[35],"laryngeal":[36],"muscles":[37],"directly":[39],"exposed":[40],"inhaled":[42],"toxins":[43],"which":[44],"may":[45,184],"the":[47,91,136,179,188],"percentage":[48,92,120,141,165],"cytochrome":[50,98,126,143,171],"c":[51,78,99,127,144,172],"oxidase":[52,100,128,145,173],"deficient":[53,146],"over":[55,195],"time.":[56,196],"Serial":[57],"sections":[58],"posterior":[60,113,161,180],"cricoarytenoid":[61,114,162,181],"control":[63,137],"strap":[64,138],"were":[66,87],"harvested":[67],"post":[68],"laryngectomy":[69],"from":[70],"10":[71],"males":[72],"age":[73,159,177],"54-78":[74],"years":[75],"old.":[76],"Cytochrome":[77],"oxidase,":[79],"succinate":[80],"dehydrogenase,":[81],"modified":[83],"Gomori":[84],"trichrome":[85],"stains":[86],"used":[88,107],"determine":[90,109],"type":[94,122,167],"I":[95,123,168],"deficiency.":[101],"Staining":[102],"myosin":[104],"antibodies":[105],"was":[106,148],"fiber":[110],"type.":[111],"The":[112,140,164],"contained":[116],"a":[117],"significantly":[118,150],"higher":[119],"deficiency":[129,174],"(p=.002,":[130],"t":[131],"=":[132,153],"4.939)":[133],"compared":[134],"muscle.":[139,163],"also":[149],"correlated":[151],"(r":[152],"+.851;":[154],"p":[155],"<":[156],".01)":[157],"increases":[175],"be":[185],"due":[186]},"counts_by_year":[{"year":2020,"cited_by_count":1}],"updated_date":"2026-11-06T12:05:46.655746","created_date":"2016-06-24T00:00:00"}
