{"id":"https://openalex.org/W3051678492","doi":"https://doi.org/10.29121/granthaalayah.v7.i2.2019.992","title":"PHYSICO-CHEMICAL AND PHYTOCHEMICAL SCREENING OF n-HEXANE EXTRACT OF LEPTADENIA HASTATA LEAVES: A PROPOSED HERBAL REMEDY IN THE TREATMENT OF DIABETES MELLITUS","display_name":"PHYSICO-CHEMICAL AND PHYTOCHEMICAL SCREENING OF n-HEXANE EXTRACT OF LEPTADENIA HASTATA LEAVES: A PROPOSED HERBAL REMEDY IN THE TREATMENT OF DIABETES MELLITUS","publication_year":2019,"publication_date":"2019-03-31","ids":{"openalex":"https://openalex.org/W3051678492","doi":"https://doi.org/10.29121/granthaalayah.v7.i2.2019.992","mag":"3051678492"},"language":"en","primary_location":{"id":"doi:10.29121/granthaalayah.v7.i2.2019.992","doi":"https://doi.org/10.29121/granthaalayah.v7.i2.2019.992","is_oa":true,"landing_page_url":"https://doi.org/10.29121/granthaalayah.v7.i2.2019.992","pdf_url":"https://www.granthaalayahpublication.org/journals/index.php/granthaalayah/article/download/IJRG19_A02_2109/870","source":{"id":"https://openalex.org/S4210201586","display_name":"International Journal of Research -GRANTHAALAYAH","issn_l":"2350-0530","issn":["2350-0530","2394-3629"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4322614449","host_organization_name":"Granthaalayah Publications and Printers","host_organization_lineage":["https://openalex.org/P4322614449"],"host_organization_lineage_names":["Granthaalayah Publications and Printers"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Research -GRANTHAALAYAH","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://www.granthaalayahpublication.org/journals/index.php/granthaalayah/article/download/IJRG19_A02_2109/870","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5054179872","display_name":"Martha Orendu Oche Attah","orcid":"https://orcid.org/0000-0002-3954-9186","observed_orcids":["https://orcid.org/0000-0002-3954-9186"]},"institutions":[{"id":"https://openalex.org/I64351976","display_name":"University of Maiduguri","ror":"https://ror.org/016na8197","country_code":"NG","type":"education","lineage":["https://openalex.org/I64351976"]}],"countries":["NG"],"is_corresponding":false,"raw_author_name":"Attah M.O.O","raw_affiliation_strings":["Department of Human Anatomy, College of Medical Sciences, University of Maiduguri, P.M.B. 1069, Maiduguri, Borno State, Nigeria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Human Anatomy, College of Medical Sciences, University of Maiduguri, P.M.B. 1069, Maiduguri, Borno State, Nigeria","institution_ids":["https://openalex.org/I64351976"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036698817","display_name":"Tamunotonye Watson Jacks","orcid":"https://orcid.org/0000-0002-1096-2997","observed_orcids":["https://orcid.org/0000-0002-1096-2997"]},"institutions":[{"id":"https://openalex.org/I96576516","display_name":"Rivers State University","ror":"https://ror.org/01kr7aq59","country_code":"NG","type":"education","lineage":["https://openalex.org/I96576516"]}],"countries":["NG"],"is_corresponding":false,"raw_author_name":"Jacks T.W","raw_affiliation_strings":["Department of Human Anatomy, Rivers State University, Port-Harcourt, Rivers State, Nigeria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Human Anatomy, Rivers State University, Port-Harcourt, Rivers State, Nigeria","institution_ids":["https://openalex.org/I96576516"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064370907","display_name":"Sani Hyedima Garba","orcid":"https://orcid.org/0000-0001-6165-0064","observed_orcids":["https://orcid.org/0000-0001-6165-0064"]},"institutions":[{"id":"https://openalex.org/I64351976","display_name":"University of Maiduguri","ror":"https://ror.org/016na8197","country_code":"NG","type":"education","lineage":["https://openalex.org/I64351976"]}],"countries":["NG"],"is_corresponding":false,"raw_author_name":"Garba S.H.","raw_affiliation_strings":["Department of Human Anatomy, College of Medical Sciences, University of Maiduguri, P.M.B. 1069, Maiduguri, Borno State, Nigeria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Human Anatomy, College of Medical Sciences, University of Maiduguri, P.M.B. 1069, Maiduguri, Borno State, Nigeria","institution_ids":["https://openalex.org/I64351976"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5038042066","display_name":"Mshelia H.E.","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I55202024","display_name":"Usmanu Danfodiyo University","ror":"https://ror.org/006er0w72","country_code":"NG","type":"education","lineage":["https://openalex.org/I55202024"]}],"countries":["NG"],"is_corresponding":false,"raw_author_name":"Mshelia H.E.","raw_affiliation_strings":["Department of Pharmacognosy and Ethnopharmacy, Faculty of Pharmaceutical Sciences, Usman Dan-fodio University, Sokoto, Sokoto State, Nigeria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacognosy and Ethnopharmacy, Faculty of Pharmaceutical Sciences, Usman Dan-fodio University, Sokoto, Sokoto State, Nigeria","institution_ids":["https://openalex.org/I55202024"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.2727,"has_fulltext":true,"cited_by_count":9,"citation_normalized_percentile":{"value":0.78559046,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"7","issue":"2","first_page":"45","last_page":"57"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T14521","display_name":"Medicinal Plant Research","score":0.7461000084877014,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T14521","display_name":"Medicinal Plant Research","score":0.7461000084877014,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11140","display_name":"Natural Antidiabetic Agents Studies","score":0.20360000431537628,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12657","display_name":"Phytochemistry Medicinal Plant Applications","score":0.02500000037252903,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/leptadenia-hastata","display_name":"Leptadenia hastata","score":1.0},{"id":"https://openalex.org/keywords/diabetes-mellitus","display_name":"diabetes mellitus","score":0.8050000071525574},{"id":"https://openalex.org/keywords/phytochemical-screening","display_name":"phytochemical screening","score":0.9700000286102295},{"id":"https://openalex.org/keywords/elemental-analysis","display_name":"elemental analysis","score":0.7639999985694885},{"id":"https://openalex.org/keywords/trace-elements","display_name":"trace elements","score":0.7580000162124634},{"id":"https://openalex.org/keywords/steroids","display_name":"steroids","score":0.6779999732971191},{"id":"https://openalex.org/keywords/triterpenoids","display_name":"triterpenoids","score":0.9990000128746033},{"id":"https://openalex.org/keywords/cardiac-glycosides","display_name":"cardiac glycosides","score":0.9980000257492065},{"id":"https://openalex.org/keywords/herbal-medicine","display_name":"herbal medicine","score":0.7120000123977661},{"id":"https://openalex.org/keywords/traditional-medicine","display_name":"traditional medicine","score":0.7929999828338623},{"id":"https://openalex.org/keywords/plant-extract-toxicity","display_name":"plant extract toxicity","score":0.3919999897480011}],"concepts":[{"id":"https://openalex.org/C195475562","wikidata":"https://www.wikidata.org/wiki/Q1639139","display_name":"Phytochemical","level":2,"score":0.9145612716674805},{"id":"https://openalex.org/C556039675","wikidata":"https://www.wikidata.org/wiki/Q771035","display_name":"Traditional medicine","level":1,"score":0.7210800647735596},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.6575255393981934},{"id":"https://openalex.org/C194671627","wikidata":"https://www.wikidata.org/wiki/Q192639","display_name":"Glycoside","level":2,"score":0.5992595553398132},{"id":"https://openalex.org/C190409667","wikidata":"https://www.wikidata.org/wiki/Q1136912","display_name":"Decoction","level":2,"score":0.5769580006599426},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5048816800117493},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.40457475185394287},{"id":"https://openalex.org/C71240020","wikidata":"https://www.wikidata.org/wiki/Q186011","display_name":"Stereochemistry","level":1,"score":0.1580173373222351},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.12243753671646118}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.29121/granthaalayah.v7.i2.2019.992","doi":"https://doi.org/10.29121/granthaalayah.v7.i2.2019.992","is_oa":true,"landing_page_url":"https://doi.org/10.29121/granthaalayah.v7.i2.2019.992","pdf_url":"https://www.granthaalayahpublication.org/journals/index.php/granthaalayah/article/download/IJRG19_A02_2109/870","source":{"id":"https://openalex.org/S4210201586","display_name":"International Journal of Research -GRANTHAALAYAH","issn_l":"2350-0530","issn":["2350-0530","2394-3629"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4322614449","host_organization_name":"Granthaalayah Publications and Printers","host_organization_lineage":["https://openalex.org/P4322614449"],"host_organization_lineage_names":["Granthaalayah Publications and Printers"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Research -GRANTHAALAYAH","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.29121/granthaalayah.v7.i2.2019.992","doi":"https://doi.org/10.29121/granthaalayah.v7.i2.2019.992","is_oa":true,"landing_page_url":"https://doi.org/10.29121/granthaalayah.v7.i2.2019.992","pdf_url":"https://www.granthaalayahpublication.org/journals/index.php/granthaalayah/article/download/IJRG19_A02_2109/870","source":{"id":"https://openalex.org/S4210201586","display_name":"International Journal of Research -GRANTHAALAYAH","issn_l":"2350-0530","issn":["2350-0530","2394-3629"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4322614449","host_organization_name":"Granthaalayah Publications and Printers","host_organization_lineage":["https://openalex.org/P4322614449"],"host_organization_lineage_names":["Granthaalayah Publications and Printers"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Research -GRANTHAALAYAH","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.8048999905586243,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3051678492.pdf","grobid_xml":"https://content.openalex.org/works/W3051678492.grobid-xml"},"referenced_works_count":25,"referenced_works":["https://openalex.org/W96454777","https://openalex.org/W1518726919","https://openalex.org/W1752227718","https://openalex.org/W1912117883","https://openalex.org/W1981175278","https://openalex.org/W1991545741","https://openalex.org/W1999669918","https://openalex.org/W2016750201","https://openalex.org/W2024712736","https://openalex.org/W2030622434","https://openalex.org/W2031718525","https://openalex.org/W2071247238","https://openalex.org/W2095035196","https://openalex.org/W2108328909","https://openalex.org/W2111675700","https://openalex.org/W2119090579","https://openalex.org/W2150997202","https://openalex.org/W2168624276","https://openalex.org/W2188099746","https://openalex.org/W2276284421","https://openalex.org/W2418645593","https://openalex.org/W2893306256","https://openalex.org/W4285719527","https://openalex.org/W4297196487","https://openalex.org/W6603659927"],"related_works":["https://openalex.org/W7128946958","https://openalex.org/W7028977337","https://openalex.org/W6949571705","https://openalex.org/W6911144885","https://openalex.org/W3134551683","https://openalex.org/W4289516710","https://openalex.org/W6968475913","https://openalex.org/W4291123168","https://openalex.org/W2969668782","https://openalex.org/W2123195950"],"abstract_inverted_index":{"Background:":[0],"Leptadenia":[1,55,159],"hastata":[2,160],"is":[3,14,25,179],"a":[4,70,164],"leafy,":[5],"climbing":[6],"plant":[7,121],"of":[8,30,54,77,88,174,197],"whose":[9],"root,":[10],"leaf":[11,24],"and":[12,59,69,79,91,101,112,140,172,188],"bark":[13],"widely":[15],"consumed":[16],"in":[17,28,50,107,144,158,169,184,194],"Northern":[18],"Nigeria.":[19],"Decoctions":[20],"made":[21],"from":[22],"the":[23,42,51,75,86,104,108,120,170,195],"locally":[26],"used":[27],"treatment":[29,196],"diabetes":[31,175,178,198],"as":[32,34,44,46],"well":[33,45],"for":[35],"numerous":[36],"trado-medicinal":[37],"processes.":[38],"This":[39],"study":[40],"investigates":[41],"physico-chemical":[43],"phytochemical":[47],"compounds":[48],"present":[49,143,157],"n-hexane":[52],"extract":[53,122],"hastata.":[56],"Method:":[57],"Physical":[58],"chemical":[60],"profile":[61],"was":[62,123],"determined":[63],"using":[64],"Smart":[65],"Spectro":[66],"test":[67],"kits":[68],"mass":[71],"spectrometer":[72],"to":[73,150],"determine":[74],"presence":[76,87],"elements":[78,127,156,186],"physical":[80],"properties.":[81],"Results:":[82],"Phytochemical":[83],"analysis":[84,96],"revealed":[85,97],"steroids,":[89],"triterpenoids":[90],"cardiac":[92],"glycosides.":[93],"The":[94],"elemental":[95],"that":[98,119],"Na,":[99],"SO4":[100],"PO4":[102],"had":[103],"highest":[105],"levels":[106],"extract.":[109],"Pb,":[110],"Hg":[111],"Cd":[113],"were":[114,142],"not":[115,124],"detected":[116],"which":[117,147],"showed":[118],"toxic.":[125],"Other":[126],"(NO4,":[128],"Mn,":[129],"Fe,":[130],"K,":[131],"Ni,":[132],"Si,":[133],"Cn,":[134],"Zn,":[135],"Ca,":[136],"Mg,":[137],"NH4,":[138],"Cr":[139],"F)":[141],"varying":[145],"concentrations":[146,187],"may":[148,161,189],"contribute":[149],"its":[151],"nutritive":[152],"composition.":[153],"Conclusions:":[154],"Various":[155],"have":[162],"either":[163],"direct":[165],"or":[166],"indirect":[167],"role":[168],"control":[171],"management":[173],"mellitus,":[176],"since":[177],"associated":[180],"with":[181],"marked":[182],"alterations":[183],"trace":[185],"replace":[190],"diminished":[191],"element":[192],"stores":[193],"mellitus.":[199]},"counts_by_year":[{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":3},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":1}],"updated_date":"2026-10-12T09:40:04.860316","created_date":"2020-08-24T00:00:00"}