{"id":"https://openalex.org/W3049743017","doi":"https://doi.org/10.3389/fbioe.2020.00991","title":"Cytocompatibility Evaluation of a Novel Series of PEG-Functionalized Lactide-Caprolactone Copolymer Biomaterials for Cardiovascular Applications","display_name":"Cytocompatibility Evaluation of a Novel Series of PEG-Functionalized Lactide-Caprolactone Copolymer Biomaterials for Cardiovascular Applications","publication_year":2020,"publication_date":"2020-08-13","ids":{"openalex":"https://openalex.org/W3049743017","doi":"https://doi.org/10.3389/fbioe.2020.00991","mag":"3049743017","pmid":"https://pubmed.ncbi.nlm.nih.gov/32903548","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/7438451"},"language":"en","primary_location":{"id":"doi:10.3389/fbioe.2020.00991","doi":"https://doi.org/10.3389/fbioe.2020.00991","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fbioe.2020.00991","pdf_url":"https://www.frontiersin.org/articles/10.3389/fbioe.2020.00991/pdf","source":{"id":"https://openalex.org/S2595131146","display_name":"Frontiers in Bioengineering and Biotechnology","issn_l":"2296-4185","issn":["2296-4185"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Bioengineering and Biotechnology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.frontiersin.org/articles/10.3389/fbioe.2020.00991/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5022090365","display_name":"Sandra Pacharra","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I904495901","display_name":"Ruhr University Bochum","ror":"https://ror.org/04tsk2644","country_code":"DE","type":"education","lineage":["https://openalex.org/I904495901"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Sandra Pacharra","raw_affiliation_strings":["Salber Laboratory, Centre for Clinical Research, Department of Experimental Surgery, Ruhr-Universit\u00e4t Bochum, Bochum, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Salber Laboratory, Centre for Clinical Research, Department of Experimental Surgery, Ruhr-Universit\u00e4t Bochum, Bochum, Germany","institution_ids":["https://openalex.org/I904495901"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014146597","display_name":"Se\u00e1n McMahon","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Se\u00e1n McMahon","raw_affiliation_strings":["Laboratory A, Synergy Centre, Ashland Specialties Ireland Ltd., Dublin, Ireland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory A, Synergy Centre, Ashland Specialties Ireland Ltd., Dublin, Ireland","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049967604","display_name":"Patrick  Emmet Duffy","orcid":"https://orcid.org/0000-0002-4483-5005","observed_orcids":["https://orcid.org/0000-0002-4483-5005"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Patrick Duffy","raw_affiliation_strings":["Laboratory A, Synergy Centre, Ashland Specialties Ireland Ltd., Dublin, Ireland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory A, Synergy Centre, Ashland Specialties Ireland Ltd., Dublin, Ireland","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053042693","display_name":"Pooja Basnett","orcid":"https://orcid.org/0000-0002-1478-6097","observed_orcids":["https://orcid.org/0000-0002-1478-6097"]},"institutions":[{"id":"https://openalex.org/I94951947","display_name":"University of Westminster","ror":"https://ror.org/04ycpbx82","country_code":"GB","type":"education","lineage":["https://openalex.org/I94951947"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Pooja Basnett","raw_affiliation_strings":["School of Life Sciences, College of Liberal Arts and Sciences, University of Westminster, London, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Life Sciences, College of Liberal Arts and Sciences, University of Westminster, London, United Kingdom","institution_ids":["https://openalex.org/I94951947"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009619421","display_name":"Wenfa Yu","orcid":"https://orcid.org/0000-0002-1413-0629","observed_orcids":["https://orcid.org/0000-0002-1413-0629"]},"institutions":[{"id":"https://openalex.org/I904495901","display_name":"Ruhr University Bochum","ror":"https://ror.org/04tsk2644","country_code":"DE","type":"education","lineage":["https://openalex.org/I904495901"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Wenfa Yu","raw_affiliation_strings":["Rosenhahn Group, Faculty of Chemistry and Biochemistry, Analytical Chemistry - Biointerfaces, Ruhr-Universit\u00e4t Bochum, Bochum, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Rosenhahn Group, Faculty of Chemistry and Biochemistry, Analytical Chemistry - Biointerfaces, Ruhr-Universit\u00e4t Bochum, Bochum, Germany","institution_ids":["https://openalex.org/I904495901"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022380426","display_name":"Sabine Seisel","orcid":"https://orcid.org/0000-0001-7390-1262","observed_orcids":["https://orcid.org/0000-0001-7390-1262"]},"institutions":[{"id":"https://openalex.org/I904495901","display_name":"Ruhr University Bochum","ror":"https://ror.org/04tsk2644","country_code":"DE","type":"education","lineage":["https://openalex.org/I904495901"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Sabine Seisel","raw_affiliation_strings":["Faculty of Chemistry and Biochemistry, Analytical Chemistry - Center for Electrochemical Sciences, Ruhr-Universit\u00e4t Bochum, Bochum, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Chemistry and Biochemistry, Analytical Chemistry - Center for Electrochemical Sciences, Ruhr-Universit\u00e4t Bochum, Bochum, Germany","institution_ids":["https://openalex.org/I904495901"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016218153","display_name":"Ulrik Stervbo","orcid":"https://orcid.org/0000-0002-2831-8868","observed_orcids":["https://orcid.org/0000-0002-2831-8868"]},"institutions":[{"id":"https://openalex.org/I2799784675","display_name":"University Hospitals of the Ruhr-University of Bochum","ror":"https://ror.org/03zcpvf19","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I2799784675"]},{"id":"https://openalex.org/I4210088550","display_name":"Universit\u00e4tsklinik Marien Hospital Herne","ror":"https://ror.org/004h6mc53","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I2799784675","https://openalex.org/I4210088550"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Ulrik Stervbo","raw_affiliation_strings":["Centre for Translational Medicine, Medical Department I, Marien Hospital Herne, University Hospital of the Ruhr-University Bochum, Herne, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre for Translational Medicine, Medical Department I, Marien Hospital Herne, University Hospital of the Ruhr-University Bochum, Herne, Germany","institution_ids":["https://openalex.org/I2799784675","https://openalex.org/I4210088550"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037283048","display_name":"Nina Babel","orcid":"https://orcid.org/0000-0003-3673-712X","observed_orcids":["https://orcid.org/0000-0003-3673-712X"]},"institutions":[{"id":"https://openalex.org/I2799784675","display_name":"University Hospitals of the Ruhr-University of Bochum","ror":"https://ror.org/03zcpvf19","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I2799784675"]},{"id":"https://openalex.org/I4210088550","display_name":"Universit\u00e4tsklinik Marien Hospital Herne","ror":"https://ror.org/004h6mc53","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I2799784675","https://openalex.org/I4210088550"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Nina Babel","raw_affiliation_strings":["Centre for Translational Medicine, Medical Department I, Marien Hospital Herne, University Hospital of the Ruhr-University Bochum, Herne, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre for Translational Medicine, Medical Department I, Marien Hospital Herne, University Hospital of the Ruhr-University Bochum, Herne, Germany","institution_ids":["https://openalex.org/I2799784675","https://openalex.org/I4210088550"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061835307","display_name":"Ipsita Roy","orcid":"https://orcid.org/0000-0001-5602-1714","observed_orcids":["https://orcid.org/0000-0001-5602-1714"]},"institutions":[{"id":"https://openalex.org/I91136226","display_name":"University of Sheffield","ror":"https://ror.org/05krs5044","country_code":"GB","type":"education","lineage":["https://openalex.org/I91136226"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Ipsita Roy","raw_affiliation_strings":["Roy Group, Kroto Innovation Centre, Department of Materials Science and Engineering, University of Sheffield, Sheffield, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Roy Group, Kroto Innovation Centre, Department of Materials Science and Engineering, University of Sheffield, Sheffield, United Kingdom","institution_ids":["https://openalex.org/I91136226"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053471997","display_name":"Richard Viebahn","orcid":"https://orcid.org/0000-0002-2051-0898","observed_orcids":["https://orcid.org/0000-0002-2051-0898"]},"institutions":[{"id":"https://openalex.org/I4210112654","display_name":"Universit\u00e4tsklinikum Knappschaftskrankenhaus Bochum","ror":"https://ror.org/024j3hn90","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I2799784675","https://openalex.org/I4210112654"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Richard Viebahn","raw_affiliation_strings":["Department of Surgery, Universit\u00e4tsklinikum Knappschaftskrankenhaus Bochum GmbH, Bochum, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Surgery, Universit\u00e4tsklinikum Knappschaftskrankenhaus Bochum GmbH, Bochum, Germany","institution_ids":["https://openalex.org/I4210112654"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100443641","display_name":"Wenxin Wang","orcid":"https://orcid.org/0000-0002-5053-0611","observed_orcids":["https://orcid.org/0000-0002-5053-0611","https://orcid.org/0000-0001-8191-3976","https://orcid.org/0009-0002-6268-7015"]},"institutions":[{"id":"https://openalex.org/I100930933","display_name":"University College Dublin","ror":"https://ror.org/05m7pjf47","country_code":"IE","type":"education","lineage":["https://openalex.org/I100930933"]}],"countries":["IE"],"is_corresponding":false,"raw_author_name":"Wenxin Wang","raw_affiliation_strings":["The Charles Institute of Dermatology, School of Medicine and Medical Science, University College Dublin, Dublin, Ireland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Charles Institute of Dermatology, School of Medicine and Medical Science, University College Dublin, Dublin, Ireland","institution_ids":["https://openalex.org/I100930933"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5056937833","display_name":"Jochen Salber","orcid":"https://orcid.org/0000-0001-9738-2305","observed_orcids":["https://orcid.org/0000-0001-9738-2305"]},"institutions":[{"id":"https://openalex.org/I4210112654","display_name":"Universit\u00e4tsklinikum Knappschaftskrankenhaus Bochum","ror":"https://ror.org/024j3hn90","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I2799784675","https://openalex.org/I4210112654"]},{"id":"https://openalex.org/I904495901","display_name":"Ruhr University Bochum","ror":"https://ror.org/04tsk2644","country_code":"DE","type":"education","lineage":["https://openalex.org/I904495901"]}],"countries":["DE"],"is_corresponding":true,"raw_author_name":"Jochen Salber","raw_affiliation_strings":["Department of Surgery, Universit\u00e4tsklinikum Knappschaftskrankenhaus Bochum GmbH, Bochum, Germany","Salber Laboratory, Centre for Clinical Research, Department of Experimental Surgery, Ruhr-Universit\u00e4t Bochum, Bochum, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Surgery, Universit\u00e4tsklinikum Knappschaftskrankenhaus Bochum GmbH, Bochum, Germany","institution_ids":["https://openalex.org/I4210112654"]},{"raw_affiliation_string":"Salber Laboratory, Centre for Clinical Research, Department of Experimental Surgery, Ruhr-Universit\u00e4t Bochum, Bochum, Germany","institution_ids":["https://openalex.org/I904495901"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":7,"corresponding_author_ids":["https://openalex.org/A5056937833"],"corresponding_institution_ids":["https://openalex.org/I4210112654","https://openalex.org/I904495901"],"apc_list":{"value":2950,"currency":"USD","value_usd":2950},"apc_paid":{"value":1948,"currency":"EUR","value_usd":2100},"fwci":0.3062,"has_fulltext":true,"cited_by_count":25,"citation_normalized_percentile":{"value":0.37306036,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":93,"max":99},"biblio":{"volume":"8","issue":null,"first_page":"991","last_page":"991"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10661","display_name":"biodegradable polymer synthesis and properties","score":0.9868000149726868,"subfield":{"id":"https://openalex.org/subfields/2502","display_name":"Biomaterials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10661","display_name":"biodegradable polymer synthesis and properties","score":0.9868000149726868,"subfield":{"id":"https://openalex.org/subfields/2502","display_name":"Biomaterials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10859","display_name":"Polymer Surface Interaction Studies","score":0.010599999688565731,"subfield":{"id":"https://openalex.org/subfields/2508","display_name":"Surfaces, Coatings and Films"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10193","display_name":"Coronary Interventions and Diagnostics","score":0.000699999975040555,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/polyethylene-glycol-functionalization","display_name":"polyethylene glycol functionalization","score":0.7919999957084656},{"id":"https://openalex.org/keywords/cytocompatibility","display_name":"cytocompatibility","score":0.7820000052452087},{"id":"https://openalex.org/keywords/hemocompatibility","display_name":"hemocompatibility","score":1.0},{"id":"https://openalex.org/keywords/endothelial-cell-adhesion","display_name":"endothelial cell adhesion","score":0.9300000071525574},{"id":"https://openalex.org/keywords/platelet-adhesion","display_name":"platelet adhesion","score":0.9900000095367432},{"id":"https://openalex.org/keywords/leukocyte-activation","display_name":"leukocyte activation","score":0.9190000295639038},{"id":"https://openalex.org/keywords/hemolysis","display_name":"hemolysis","score":0.9700000286102295},{"id":"https://openalex.org/keywords/water-contact-angle","display_name":"water contact angle","score":0.7009999752044678},{"id":"https://openalex.org/keywords/thrombosis","display_name":"thrombosis","score":0.5860000252723694}],"concepts":[{"id":"https://openalex.org/C15920480","wikidata":"https://www.wikidata.org/wiki/Q421281","display_name":"Copolymer","level":3,"score":0.8199734687805176},{"id":"https://openalex.org/C2781111393","wikidata":"https://www.wikidata.org/wiki/Q288104","display_name":"Caprolactone","level":4,"score":0.7495144605636597},{"id":"https://openalex.org/C54400483","wikidata":"https://www.wikidata.org/wiki/Q1793202","display_name":"PEG ratio","level":2,"score":0.5953370332717896},{"id":"https://openalex.org/C2776743539","wikidata":"https://www.wikidata.org/wiki/Q421313","display_name":"Lactide","level":4,"score":0.44103485345840454},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.42745110392570496},{"id":"https://openalex.org/C188027245","wikidata":"https://www.wikidata.org/wiki/Q750446","display_name":"Polymer chemistry","level":1,"score":0.3728855848312378},{"id":"https://openalex.org/C521977710","wikidata":"https://www.wikidata.org/wiki/Q81163","display_name":"Polymer","level":2,"score":0.09338873624801636},{"id":"https://openalex.org/C159985019","wikidata":"https://www.wikidata.org/wiki/Q181790","display_name":"Composite material","level":1,"score":0.05345997214317322},{"id":"https://openalex.org/C10138342","wikidata":"https://www.wikidata.org/wiki/Q43015","display_name":"Finance","level":1,"score":0.0},{"id":"https://openalex.org/C162324750","wikidata":"https://www.wikidata.org/wiki/Q8134","display_name":"Economics","level":0,"score":0.0}],"mesh":[],"locations_count":7,"locations":[{"id":"doi:10.3389/fbioe.2020.00991","doi":"https://doi.org/10.3389/fbioe.2020.00991","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fbioe.2020.00991","pdf_url":"https://www.frontiersin.org/articles/10.3389/fbioe.2020.00991/pdf","source":{"id":"https://openalex.org/S2595131146","display_name":"Frontiers in Bioengineering and Biotechnology","issn_l":"2296-4185","issn":["2296-4185"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Bioengineering and Biotechnology","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:7438451","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/7438451","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Front Bioeng Biotechnol","raw_type":"Text"},{"id":"pmid:32903548","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/32903548","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in bioengineering and biotechnology","raw_type":"Journal Article"},{"id":"pmh:oai:eprints.whiterose.ac.uk:165024","doi":null,"is_oa":false,"landing_page_url":"http://eprints.whiterose.ac.uk/165024/1/fbioe-08-00991.pdf","pdf_url":"http://eprints.whiterose.ac.uk/165024/1/fbioe-08-00991.pdf","source":{"id":"https://openalex.org/S4306400854","display_name":"White Rose Research Online (University of Leeds, The University of Sheffield, University of York)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2800616092","host_organization_name":"White Rose University Consortium","host_organization_lineage":["https://openalex.org/I2800616092"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"","raw_type":"Article"},{"id":"pmh:oai:westminsterresearch.westminster.ac.uk:v0634","doi":null,"is_oa":true,"landing_page_url":"https://doi.org/10.3389/fbioe.2020.00991","pdf_url":null,"source":{"id":"https://openalex.org/S4306400277","display_name":"WestminsterResearch (University of Westminster)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I94951947","host_organization_name":"University of Westminster","host_organization_lineage":["https://openalex.org/I94951947"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"","raw_type":"article"},{"id":"pmh:oai:hss-opus.ub.ruhr-uni-bochum.de:7597","doi":null,"is_oa":true,"landing_page_url":"https://hss-opus.ub.ruhr-uni-bochum.de/opus4/frontdoor/index/index/docId/7597","pdf_url":"https://hss-opus.ub.ruhr-uni-bochum.de/opus4/frontdoor/index/index/docId/7597","source":{"id":"https://openalex.org/S4306400167","display_name":"Dokumentenrepositorium der RUB (Ruhr University Bochum)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I904495901","host_organization_name":"Ruhr University Bochum","host_organization_lineage":["https://openalex.org/I904495901"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"article"},{"id":"pmh:oai:doaj.org/article:59cebf76103c493daa0f2a5d4c669914","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/59cebf76103c493daa0f2a5d4c669914","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Frontiers in Bioengineering and Biotechnology, Vol 8 (2020)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.3389/fbioe.2020.00991","doi":"https://doi.org/10.3389/fbioe.2020.00991","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fbioe.2020.00991","pdf_url":"https://www.frontiersin.org/articles/10.3389/fbioe.2020.00991/pdf","source":{"id":"https://openalex.org/S2595131146","display_name":"Frontiers in Bioengineering and Biotechnology","issn_l":"2296-4185","issn":["2296-4185"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Bioengineering and Biotechnology","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.98580002784729,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G6593665238","display_name":null,"funder_award_id":"EBPPG/2014/70","funder_id":"https://openalex.org/F4320321056","funder_display_name":"Irish Research Council"},{"id":"https://openalex.org/G7601932681","display_name":"Reinforced Bioresorbable Biomaterials for Therapeutic Drug Eluting Stents","funder_award_id":"604251","funder_id":"https://openalex.org/F4320320300","funder_display_name":"European Commission"}],"funders":[{"id":"https://openalex.org/F4320320300","display_name":"European Commission","ror":"https://ror.org/00k4n6c32"},{"id":"https://openalex.org/F4320321056","display_name":"Irish Research Council","ror":"https://ror.org/051xex213"},{"id":"https://openalex.org/F4320333065","display_name":"Seventh Framework Programme","ror":null}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3049743017.pdf","grobid_xml":"https://content.openalex.org/works/W3049743017.grobid-xml"},"referenced_works_count":58,"referenced_works":["https://openalex.org/W67789468","https://openalex.org/W78479461","https://openalex.org/W117135166","https://openalex.org/W124057337","https://openalex.org/W761787561","https://openalex.org/W1511700350","https://openalex.org/W1581527645","https://openalex.org/W1795635013","https://openalex.org/W1893534297","https://openalex.org/W1966339848","https://openalex.org/W1966775740","https://openalex.org/W1968073577","https://openalex.org/W1969720022","https://openalex.org/W1983387794","https://openalex.org/W1991814072","https://openalex.org/W1999528452","https://openalex.org/W2002420618","https://openalex.org/W2008952364","https://openalex.org/W2017150085","https://openalex.org/W2022434323","https://openalex.org/W2031637644","https://openalex.org/W2037338397","https://openalex.org/W2046324591","https://openalex.org/W2049382198","https://openalex.org/W2050575070","https://openalex.org/W2052683618","https://openalex.org/W2052745234","https://openalex.org/W2053780932","https://openalex.org/W2054432898","https://openalex.org/W2065582613","https://openalex.org/W2071083599","https://openalex.org/W2072895904","https://openalex.org/W2084529035","https://openalex.org/W2086558996","https://openalex.org/W2087755046","https://openalex.org/W2088712159","https://openalex.org/W2134417023","https://openalex.org/W2136019015","https://openalex.org/W2152667707","https://openalex.org/W2154758223","https://openalex.org/W2158209655","https://openalex.org/W2160768548","https://openalex.org/W2166171010","https://openalex.org/W2167815042","https://openalex.org/W2202994501","https://openalex.org/W2262338887","https://openalex.org/W2264165696","https://openalex.org/W2313043396","https://openalex.org/W2335017003","https://openalex.org/W2498401753","https://openalex.org/W2508797694","https://openalex.org/W2520041543","https://openalex.org/W2809327439","https://openalex.org/W2885679047","https://openalex.org/W3021727476","https://openalex.org/W4231411606","https://openalex.org/W4236769954","https://openalex.org/W6604798539"],"related_works":["https://openalex.org/W2023323308","https://openalex.org/W2993935756","https://openalex.org/W2089301017","https://openalex.org/W7221056230","https://openalex.org/W2087842828","https://openalex.org/W2076237901","https://openalex.org/W4375933890","https://openalex.org/W2265970762","https://openalex.org/W2885679047","https://openalex.org/W2023972020"],"abstract_inverted_index":{"Although":[0],"the":[1,25,29,49,56,124,142,183,200,230,251],"use":[2,224],"of":[3,28,39,58,65,111,141,175,232,255],"bioresorbable":[4,32,61],"materials":[5,103,201,241],"in":[6,46,109,182,246,253,266],"stent":[7,34,247],"production":[8,262],"is":[9,74,98,129],"thought":[10],"to":[11,16,48,54,131,250,260],"improve":[12],"long-term":[13],"safety":[14],"compared":[15],"their":[17,105,264],"durable":[18],"counterparts,":[19],"a":[20,63,77,87,226],"recent":[21],"FDA":[22],"report":[23],"on":[24,146],"two-year":[26],"follow-up":[27],"first":[30,59],"FDA-approved":[31],"vascular":[33],"showed":[35],"an":[36,244],"increased":[37],"occurrence":[38],"major":[40],"adverse":[41],"cardiac":[42],"events":[43],"and":[44,81,107,118,135,159,205,214,263,269],"thrombosis":[45],"comparison":[47],"metallic":[50],"control.":[51],"In":[52],"order":[53],"overcome":[55],"issues":[57],"generation":[60],"polymers,":[62],"series":[64],"polyethylene":[66],"glycol-functionalized":[67],"poly-L-lactide-co-\u025b-caprolactone":[68],"copolymers":[69],"with":[70],"varying":[71,123],"lactide-to-caprolactone":[72,125],"content":[73],"developed":[75,151],"using":[76],"novel":[78],"one-step":[79,257],"PEG-functionalization":[80],"copolymerization":[82],"strategy.":[83],"This":[84],"approach":[85],"represents":[86],"new":[88],"facile":[89],"way":[90],"towards":[91],"surface":[92],"enhancement":[93],"for":[94,168,221,243],"cellular":[95],"interaction,":[96],"which":[97,138,171],"shown":[99],"by":[100],"screening":[101],"these":[102,236],"regarding":[104],"cyto-":[106,268],"hemocompatibility":[108],"terms":[110],"cytotoxicity,":[112],"hemolysis,":[113],"platelet":[114,136],"adhesion,":[115],"leucocyte":[116,156],"activation":[117,157],"endothelial":[119,134,210],"cell":[120,211],"adhesion.":[121,212],"By":[122],"polymer":[126,147],"composition,":[127],"it":[128],"possible":[130],"gradually":[132],"affect":[133],"adhesion":[137],"allows":[139],"fine-tuning":[140],"biological":[143],"response":[144],"based":[145],"chemistry.":[148],"All":[149],"polymers":[150,184,237],"were":[152,180],"non-cytotoxic,":[153],"had":[154],"acceptable":[155],"levels":[158],"presented":[160,172,217],"non-hemolytic":[161],"(<":[162],"2%":[163],"hemolysis":[164,173],"rate)":[165],"behavior":[166],"except":[167],"PLCL-PEG":[169],"55:45":[170],"rate":[174],"2.5%\u00b10.5.":[176],"Water":[177],"contact":[178],"angles":[179],"reduced":[181],"containing":[185],"PEG":[186],"functionalization":[187],"(PLLA-PEG:":[188],"69.8\u00b0\u00b12.3,":[189],"PCL-PEG:":[190],"61.2\u00b0\u00b17.5)":[191],"versus":[192],"those":[193],"without":[194],"(PLLA:":[195],"79.5\u00b0\u00b13.2,":[196],"PCL:":[197],"76.4\u00b0\u00b110.2)":[198],"while":[199],"PCL-PEG550,":[202],"PLCL-PEG550":[203,206,215],"90:10":[204],"70:30":[207,216],"demonstrated":[208],"best":[209,219],"PLLA-PEG550":[213],"as":[218],"candidates":[220],"cardiovascular":[222],"implant":[223],"from":[225],"cytocompatibility":[227],"perspective":[228],"across":[229],"spectrum":[231],"testing":[233],"completed.":[234],"Altogether,":[235],"are":[238],"excellent":[239,265],"innovative":[240],"suited":[242],"application":[245],"manufacture":[248],"due":[249],"ease":[252],"translation":[254],"this":[256],"synthesis":[258],"strategy":[259],"device":[261],"vitro":[267],"hemocompatibility.":[270]},"counts_by_year":[{"year":2026,"cited_by_count":8},{"year":2025,"cited_by_count":7},{"year":2024,"cited_by_count":5},{"year":2023,"cited_by_count":3},{"year":2021,"cited_by_count":2}],"updated_date":"2026-10-30T12:39:25.321706","created_date":"2020-08-21T00:00:00"}