{"id":"https://openalex.org/W3049549452","doi":null,"title":"A Comparative Quantification in Cellularity of Bone Marrow Aspirated with two New Harvesting Devices, and The Non-equivalent Difference Between A Centrifugated Bone Marrow Concentrate And A Bone Marrow Aspirate As Biological Injectates, Using A Bi-Lateral Patient Model","display_name":"A Comparative Quantification in Cellularity of Bone Marrow Aspirated with two New Harvesting Devices, and The Non-equivalent Difference Between A Centrifugated Bone Marrow Concentrate And A Bone Marrow Aspirate As Biological Injectates, Using A Bi-Lateral Patient Model","publication_year":2020,"publication_date":"2020-01-01","ids":{"openalex":"https://openalex.org/W3049549452","mag":"3049549452"},"language":"en","primary_location":{"id":"mag:3049549452","doi":null,"is_oa":true,"landing_page_url":"https://www.longdom.org/open-access/a-comparative-quantification-in-cellularity-of-bone-marrow-aspirated-with-two-new-harvesting-devices-and-the-nonequivale.pdf","pdf_url":null,"source":{"id":"https://openalex.org/S2764349506","display_name":"Journal of Stem Cell Research & Therapy","issn_l":"2157-7633","issn":["2157-7633"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4310320466","host_organization_name":"OMICS Publishing Group","host_organization_lineage":["https://openalex.org/P4310320466"],"host_organization_lineage_names":["OMICS Publishing Group"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Journal of Stem Cell Research & Therapy","raw_type":null},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://www.longdom.org/open-access/a-comparative-quantification-in-cellularity-of-bone-marrow-aspirated-with-two-new-harvesting-devices-and-the-nonequivale.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5047458376","display_name":"Peter Albert Everts","orcid":"https://orcid.org/0000-0003-3128-9380","observed_orcids":["https://orcid.org/0000-0003-3128-9380"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Peter A. Everts","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-3128-9380","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031013309","display_name":"John L. Ferrell","orcid":"https://orcid.org/0009-0002-6065-9248","observed_orcids":["https://orcid.org/0009-0002-6065-9248"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"John Ferrell","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0009-0002-6065-9248","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081661606","display_name":"Christine Brown Mahoney","orcid":"https://orcid.org/0000-0002-5138-9795","observed_orcids":["https://orcid.org/0000-0002-5138-9795"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Christine Brown Mahoney","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-5138-9795","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038422337","display_name":"Glenn Flanagan","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Glenn Flanagan","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5028460964","display_name":"Moises Irizarry-de Roman","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Moises Irizarry-de Roman","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083489405","display_name":"Rowan V. Paul","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Rowan Paul","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111747399","display_name":"Natalie A. Stephens","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Natalie Stephens","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5042922584","display_name":"Kenneth Mautner","orcid":"https://orcid.org/0000-0001-8458-0126","observed_orcids":["https://orcid.org/0000-0001-8458-0126"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Kenneth Mautner","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-8458-0126","affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.6838,"has_fulltext":false,"cited_by_count":9,"citation_normalized_percentile":{"value":0.67092837,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":93,"max":96},"biblio":{"volume":"10","issue":"5","first_page":"1","last_page":"10"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11570","display_name":"Periodontal Regeneration and Treatments","score":0.8784000277519226,"subfield":{"id":"https://openalex.org/subfields/3506","display_name":"Periodontics"},"field":{"id":"https://openalex.org/fields/35","display_name":"Dentistry"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11570","display_name":"Periodontal Regeneration and Treatments","score":0.8784000277519226,"subfield":{"id":"https://openalex.org/subfields/3506","display_name":"Periodontics"},"field":{"id":"https://openalex.org/fields/35","display_name":"Dentistry"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10176","display_name":"Mesenchymal stem cell research","score":0.1031000018119812,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10345","display_name":"Hematopoietic Stem Cell Transplantation","score":0.011699999682605267,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/bone-marrow-aspirate","display_name":"bone marrow aspirate","score":0.8450000286102295},{"id":"https://openalex.org/keywords/bone-marrow-aspirate-concentrate","display_name":"bone marrow aspirate concentrate","score":0.8849999904632568},{"id":"https://openalex.org/keywords/cellularity","display_name":"cellularity","score":0.7210000157356262},{"id":"https://openalex.org/keywords/cd34-cells","display_name":"CD34+ cells","score":0.9959999918937683},{"id":"https://openalex.org/keywords/total-nucleated-cells","display_name":"total nucleated cells","score":0.9520000219345093},{"id":"https://openalex.org/keywords/autologous-cell-therapy","display_name":"autologous cell therapy","score":0.6520000100135803},{"id":"https://openalex.org/keywords/hematocrit","display_name":"hematocrit","score":0.6209999918937683}],"concepts":[{"id":"https://openalex.org/C2780007613","wikidata":"https://www.wikidata.org/wiki/Q546523","display_name":"Bone marrow","level":2,"score":0.8800504207611084},{"id":"https://openalex.org/C7623868","wikidata":"https://www.wikidata.org/wiki/Q1967135","display_name":"Centrifugation","level":2,"score":0.6187282204627991},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6020802855491638},{"id":"https://openalex.org/C2908745798","wikidata":"https://www.wikidata.org/wiki/Q1777322","display_name":"Bone marrow aspirate","level":3,"score":0.5301048755645752},{"id":"https://openalex.org/C89560881","wikidata":"https://www.wikidata.org/wiki/Q101026","display_name":"Platelet","level":2,"score":0.5145506262779236},{"id":"https://openalex.org/C10205521","wikidata":"https://www.wikidata.org/wiki/Q4035578","display_name":"CD34","level":3,"score":0.4580913484096527},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.4450836181640625},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.34966567158699036},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.2068805992603302},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.16229933500289917},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.13671091198921204},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.1292273998260498},{"id":"https://openalex.org/C28328180","wikidata":"https://www.wikidata.org/wiki/Q48196","display_name":"Stem cell","level":2,"score":0.10757160186767578},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"mag:3049549452","doi":null,"is_oa":true,"landing_page_url":"https://www.longdom.org/open-access/a-comparative-quantification-in-cellularity-of-bone-marrow-aspirated-with-two-new-harvesting-devices-and-the-nonequivale.pdf","pdf_url":null,"source":{"id":"https://openalex.org/S2764349506","display_name":"Journal of Stem Cell Research & Therapy","issn_l":"2157-7633","issn":["2157-7633"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4310320466","host_organization_name":"OMICS Publishing Group","host_organization_lineage":["https://openalex.org/P4310320466"],"host_organization_lineage_names":["OMICS Publishing Group"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Journal of Stem Cell Research & Therapy","raw_type":null}],"best_oa_location":{"id":"mag:3049549452","doi":null,"is_oa":true,"landing_page_url":"https://www.longdom.org/open-access/a-comparative-quantification-in-cellularity-of-bone-marrow-aspirated-with-two-new-harvesting-devices-and-the-nonequivale.pdf","pdf_url":null,"source":{"id":"https://openalex.org/S2764349506","display_name":"Journal of Stem Cell Research & Therapy","issn_l":"2157-7633","issn":["2157-7633"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4310320466","host_organization_name":"OMICS Publishing Group","host_organization_lineage":["https://openalex.org/P4310320466"],"host_organization_lineage_names":["OMICS Publishing Group"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Journal of Stem Cell Research & Therapy","raw_type":null},"sustainable_development_goals":[{"score":0.9763000011444092,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":30,"referenced_works":["https://openalex.org/W1532162953","https://openalex.org/W1966745575","https://openalex.org/W1968628080","https://openalex.org/W2026254409","https://openalex.org/W2039389119","https://openalex.org/W2043060398","https://openalex.org/W2082001997","https://openalex.org/W2116500923","https://openalex.org/W2120008277","https://openalex.org/W2120910826","https://openalex.org/W2334057596","https://openalex.org/W2510836668","https://openalex.org/W2539654581","https://openalex.org/W2593322983","https://openalex.org/W2606593883","https://openalex.org/W2614290614","https://openalex.org/W2733596679","https://openalex.org/W2765979567","https://openalex.org/W2775249153","https://openalex.org/W2782500847","https://openalex.org/W2784604032","https://openalex.org/W2796735654","https://openalex.org/W2897895578","https://openalex.org/W2912497743","https://openalex.org/W2945342539","https://openalex.org/W2947802871","https://openalex.org/W3000658764","https://openalex.org/W3005690837","https://openalex.org/W3010248556","https://openalex.org/W4300374239"],"related_works":["https://openalex.org/W7164519107","https://openalex.org/W2912497743","https://openalex.org/W2945342539","https://openalex.org/W4200539355","https://openalex.org/W2334057596","https://openalex.org/W3000658764","https://openalex.org/W4411494784","https://openalex.org/W2984241356","https://openalex.org/W4411961914","https://openalex.org/W2740274844"],"abstract_inverted_index":{"The":[0,86,265],"first":[1],"aim":[2,88],"of":[3,13,94,97,101,128,150,179,249,270],"this":[4],"study":[5],"was":[6,84,89,139],"to":[7,42,90,105,183,227,299,307,322],"examine":[8],"the":[9,25,33,69,92,133,148,184,187,191,204,247,250,284,305],"cellularity":[10],"and":[11,32,161,200,210,212,220,238,252,276,296,325],"quality":[12],"autologous":[14],"bone":[15,27,36,44,103,108,116,129,193,291],"marrow":[16,28,37,45,59,75,104,109,117,130,194,257,292],"aspirates":[17],"harvested":[18,131],"with":[19,120,122,172,217],"two":[20],"novel":[21],"FDA-cleared":[22],"devices,":[23],"namely":[24],"Aspire\u2122":[26],"aspiration":[29,38],"system":[30],"(AS-BMAS)":[31],"Marrow":[34],"Cellution":[35],"device":[39],"(MC-BMAD).":[40],"Compared":[41],"traditional":[43],"harvesting":[46,82],"needle":[47],"systems,":[48],"both":[49],"these":[50],"devices":[51],"have":[52],"a":[53,80,98,107,123,167,229,294,301,314,323],"closed":[54],"distal":[55],"tip,":[56],"avoiding":[57],"preferential":[58],"collection":[60],"(peripheral":[61],"blood":[62],"aspiration)":[63],"from":[64],"deeper":[65],"cavity":[66],"regions,":[67],"whereas":[68],"side":[70],"holes":[71],"facilitate":[72],"more":[73],"horizontal":[74],"extraction.":[76],"In":[77,186],"all":[78,142],"patients,":[79],"similar":[81],"technique":[83],"used.":[85],"second":[87],"demonstrate":[91],"effectiveness":[93],"mechanical":[95],"centrifugation":[96,127],"large":[99],"volume":[100],"extracted":[102],"produce":[106,228,300],"concentrate":[110],"(BMC).":[111],"Finally,":[112],"we":[113],"directly":[114],"compared":[115,321],"constituents":[118],"aspirated":[119],"MC-BMAD":[121,205],"BMC,":[124],"generated":[125],"by":[126],"using":[132],"AS-BMAS.":[134],"A":[135,177,242],"bi-lateral":[136],"patient":[137],"model":[138],"used":[140],"for":[141,328],"comparisons.":[143],"All":[144],"cellular":[145,244],"analyses":[146],"included":[147],"measurement":[149],"Colony-Forming":[151],"Units-fibroblasts":[152],"(CFU/f)":[153],"levels,":[154],"CD34+cells/ml,":[155],"Total":[156],"Nucleated":[157],"Cells":[158,164],"(TNCs)/ml,":[159],"platelets/ml,":[160],"Red":[162],"Blood":[163],"(RBCs)/ml":[165],"in":[166,263,317],"single,":[168],"FDA-approved":[169],"laboratory,":[170],"compliant":[171],"Good":[173],"Manufacturing":[174],"Practice":[175],"regulations.":[176],"total":[178],"12":[180],"patients":[181],"consented":[182],"study.":[185],"direct":[188,243],"BMA":[189,225,327],"comparison,":[190],"AS-BMAS":[192,256,266],"yielded":[195],"significantly":[196],"higher":[197],"CFU/f":[198],"counts":[199],"TNC":[201],"concentrations":[202,269],"than":[203],"(1,060/ml,":[206],"33.5":[207],"\u00d7":[208,214],"106/ml,":[209,215],"610/ml":[211],"28.6":[213],"respectively),":[216],"comparable":[218],"platelet":[219],"RBC":[221],"concentrations.":[222],"Data":[223],"following":[224,255],"concentration":[226],"BMC":[230,254,302,318],"revealed":[231],"highly":[232,260],"significant":[233,261],"cell":[234,268],"yields,":[235],"fewer":[236],"RBCs,":[237],"lower":[239],"hematocrit":[240],"(HCT).":[241],"comparison":[245],"between":[246],"aspirate":[248],"MCBMAD":[251],"centrifugated":[253],"extraction":[258],"showed":[259],"differences":[262],"cellularity.":[264],"produced":[267],"CFU/f,":[271],"CD34+":[272],"cells,":[273],"TNCs,":[274],"platelets,":[275],"RBCs":[277],"that":[278,289,303],"were":[279],"comparable,":[280],"or":[281],"greater":[282],"than,":[283],"predicate":[285],"device.":[286],"We":[287],"believe":[288],"concentrating":[290],"is":[293],"consistent":[295],"safe":[297],"method":[298],"has":[304],"potential":[306],"be":[308],"clinically":[309],"effective.":[310],"Furthermore,":[311],"data":[312],"indicate":[313],"non-equivalent":[315],"difference":[316],"cellularity,":[319],"when":[320],"non-filtered":[324],"non-centrifugated":[326],"clinical":[329],"use.":[330]},"counts_by_year":[{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":3},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":2}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2020-08-21T00:00:00"}