{"id":"https://openalex.org/W3047717040","doi":"https://doi.org/10.1002/mrc.5084","title":"Probing short and long\u2010range interactions in native collagen inside the bone matrix by BioSolids CryoProbe","display_name":"Probing short and long\u2010range interactions in native collagen inside the bone matrix by BioSolids CryoProbe","publication_year":2020,"publication_date":"2020-08-05","ids":{"openalex":"https://openalex.org/W3047717040","doi":"https://doi.org/10.1002/mrc.5084","mag":"3047717040","pmid":"https://pubmed.ncbi.nlm.nih.gov/32761649"},"language":"en","primary_location":{"id":"doi:10.1002/mrc.5084","doi":"https://doi.org/10.1002/mrc.5084","is_oa":false,"landing_page_url":"https://doi.org/10.1002/mrc.5084","pdf_url":null,"source":{"id":"https://openalex.org/S112856106","display_name":"Magnetic Resonance in Chemistry","issn_l":"0749-1581","issn":["0749-1581","1097-458X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","poland-40","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Magnetic Resonance in Chemistry","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5076078746","display_name":"Nidhi G. Tiwari","orcid":"https://orcid.org/0000-0002-9637-3471","observed_orcids":["https://orcid.org/0000-0002-9637-3471"]},"institutions":[{"id":"https://openalex.org/I161370692","display_name":"Sanjay Gandhi Post Graduate Institute of Medical Sciences","ror":"https://ror.org/01rsgrz10","country_code":"IN","type":"facility","lineage":["https://openalex.org/I161370692"]},{"id":"https://openalex.org/I4210161010","display_name":"Centre of Biomedical Research","ror":"https://ror.org/05xkqnm68","country_code":"IN","type":"facility","lineage":["https://openalex.org/I4210161010"]},{"id":"https://openalex.org/I91357014","display_name":"Banaras Hindu University","ror":"https://ror.org/04cdn2797","country_code":"IN","type":"education","lineage":["https://openalex.org/I91357014"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Nidhi Tiwari","raw_affiliation_strings":["Centre of Biomedical Research, SGPGIMS Campus, Lucknow, 226014 India","Department of Chemistry, Institute of Sciences, Banaras Hindu University, Varanasi, 221005 India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre of Biomedical Research, SGPGIMS Campus, Lucknow, 226014 India","institution_ids":["https://openalex.org/I161370692","https://openalex.org/I4210161010"]},{"raw_affiliation_string":"Department of Chemistry, Institute of Sciences, Banaras Hindu University, Varanasi, 221005 India","institution_ids":["https://openalex.org/I91357014"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111986936","display_name":"Sebastian Wegner","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210140314","display_name":"Bruker (Switzerland)","ror":"https://ror.org/04hqnrz12","country_code":"CH","type":"company","lineage":["https://openalex.org/I193170854","https://openalex.org/I4210140314"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Sebastian Wegner","raw_affiliation_strings":["Bruker BioSpin Corporation  F\u00e4llanden Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bruker BioSpin Corporation  F\u00e4llanden Switzerland","institution_ids":["https://openalex.org/I4210140314"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026858116","display_name":"Alia Hassan","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210140314","display_name":"Bruker (Switzerland)","ror":"https://ror.org/04hqnrz12","country_code":"CH","type":"company","lineage":["https://openalex.org/I193170854","https://openalex.org/I4210140314"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Alia Hassan","raw_affiliation_strings":["Bruker BioSpin Corporation  F\u00e4llanden Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bruker BioSpin Corporation  F\u00e4llanden Switzerland","institution_ids":["https://openalex.org/I4210140314"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012390301","display_name":"Navneet Dwivedi","orcid":"https://orcid.org/0009-0009-2554-3670","observed_orcids":["https://orcid.org/0009-0009-2554-3670"]},"institutions":[{"id":"https://openalex.org/I161370692","display_name":"Sanjay Gandhi Post Graduate Institute of Medical Sciences","ror":"https://ror.org/01rsgrz10","country_code":"IN","type":"facility","lineage":["https://openalex.org/I161370692"]},{"id":"https://openalex.org/I189949046","display_name":"Integral University","ror":"https://ror.org/039zd5s34","country_code":"IN","type":"education","lineage":["https://openalex.org/I189949046"]},{"id":"https://openalex.org/I4210161010","display_name":"Centre of Biomedical Research","ror":"https://ror.org/05xkqnm68","country_code":"IN","type":"facility","lineage":["https://openalex.org/I4210161010"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Navneet Dwivedi","raw_affiliation_strings":["Centre of Biomedical Research, SGPGIMS Campus, Lucknow, 226014 India","Department of Physics, Integral University, Lucknow, 226026 India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre of Biomedical Research, SGPGIMS Campus, Lucknow, 226014 India","institution_ids":["https://openalex.org/I161370692","https://openalex.org/I4210161010"]},{"raw_affiliation_string":"Department of Physics, Integral University, Lucknow, 226026 India","institution_ids":["https://openalex.org/I189949046"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101861407","display_name":"R.N. Rai","orcid":"https://orcid.org/0000-0003-1681-5098","observed_orcids":["https://orcid.org/0000-0003-1681-5098"]},"institutions":[{"id":"https://openalex.org/I91357014","display_name":"Banaras Hindu University","ror":"https://ror.org/04cdn2797","country_code":"IN","type":"education","lineage":["https://openalex.org/I91357014"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"RamaNand Rai","raw_affiliation_strings":["Department of Chemistry, Institute of Sciences, Banaras Hindu University, Varanasi, 221005 India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, Institute of Sciences, Banaras Hindu University, Varanasi, 221005 India","institution_ids":["https://openalex.org/I91357014"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5055028094","display_name":"Neeraj Sinha","orcid":"https://orcid.org/0000-0003-3235-6127","observed_orcids":["https://orcid.org/0000-0003-3235-6127"]},"institutions":[{"id":"https://openalex.org/I161370692","display_name":"Sanjay Gandhi Post Graduate Institute of Medical Sciences","ror":"https://ror.org/01rsgrz10","country_code":"IN","type":"facility","lineage":["https://openalex.org/I161370692"]},{"id":"https://openalex.org/I4210161010","display_name":"Centre of Biomedical Research","ror":"https://ror.org/05xkqnm68","country_code":"IN","type":"facility","lineage":["https://openalex.org/I4210161010"]}],"countries":["IN"],"is_corresponding":true,"raw_author_name":"Neeraj Sinha","raw_affiliation_strings":["Centre of Biomedical Research, SGPGIMS Campus, Lucknow, 226014 India"],"raw_orcid":"https://orcid.org/0000-0003-3235-6127","affiliations":[{"raw_affiliation_string":"Centre of Biomedical Research, SGPGIMS Campus, Lucknow, 226014 India","institution_ids":["https://openalex.org/I161370692","https://openalex.org/I4210161010"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5055028094"],"corresponding_institution_ids":["https://openalex.org/I161370692","https://openalex.org/I4210161010"],"apc_list":{"value":3900,"currency":"USD","value_usd":3900},"apc_paid":null,"fwci":0.7422,"has_fulltext":false,"cited_by_count":13,"citation_normalized_percentile":{"value":0.58662061,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"59","issue":"2","first_page":"99","last_page":"107"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11809","display_name":"Advanced NMR Techniques and Applications","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/1607","display_name":"Spectroscopy"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T11809","display_name":"Advanced NMR Techniques and Applications","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/1607","display_name":"Spectroscopy"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12381","display_name":"Electron Spin Resonance Studies","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/1607","display_name":"Spectroscopy"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12085","display_name":"Collagen: Extraction and Characterization","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2502","display_name":"Biomaterials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/native-collagen","display_name":"native collagen","score":0.8889999985694885},{"id":"https://openalex.org/keywords/bone-matrix","display_name":"bone matrix","score":0.9279999732971191},{"id":"https://openalex.org/keywords/solid-state-nmr","display_name":"solid-state NMR","score":0.7559999823570251},{"id":"https://openalex.org/keywords/short-range-interactions","display_name":"short-range interactions","score":0.7519999742507935},{"id":"https://openalex.org/keywords/long-range-interactions","display_name":"long-range interactions","score":0.996999979019165},{"id":"https://openalex.org/keywords/collagen-self-assembly","display_name":"collagen self-assembly","score":0.7329999804496765},{"id":"https://openalex.org/keywords/bone-mineralization","display_name":"bone mineralization","score":0.8159999847412109},{"id":"https://openalex.org/keywords/cryogenic-nmr-probe","display_name":"cryogenic NMR probe","score":0.6880000233650208}],"concepts":[{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.8040772676467896},{"id":"https://openalex.org/C92381491","wikidata":"https://www.wikidata.org/wiki/Q5747409","display_name":"Heteronuclear molecule","level":3,"score":0.733931303024292},{"id":"https://openalex.org/C153202636","wikidata":"https://www.wikidata.org/wiki/Q7557802","display_name":"Solid-state nuclear magnetic resonance","level":2,"score":0.6907879114151001},{"id":"https://openalex.org/C84935128","wikidata":"https://www.wikidata.org/wiki/Q1884060","display_name":"Magic angle spinning","level":3,"score":0.5888503193855286},{"id":"https://openalex.org/C46141821","wikidata":"https://www.wikidata.org/wiki/Q209402","display_name":"Nuclear magnetic resonance","level":1,"score":0.47907835245132446},{"id":"https://openalex.org/C2777654200","wikidata":"https://www.wikidata.org/wiki/Q1776685","display_name":"Biosolids","level":2,"score":0.4193054139614105},{"id":"https://openalex.org/C66974803","wikidata":"https://www.wikidata.org/wiki/Q10359898","display_name":"Nuclear magnetic resonance spectroscopy","level":2,"score":0.3094702959060669},{"id":"https://openalex.org/C71240020","wikidata":"https://www.wikidata.org/wiki/Q186011","display_name":"Stereochemistry","level":1,"score":0.10162040591239929},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.07139381766319275},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.0},{"id":"https://openalex.org/C87717796","wikidata":"https://www.wikidata.org/wiki/Q146326","display_name":"Environmental engineering","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001857","descriptor_name":"Bone Matrix","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D002247","descriptor_name":"Carbon Isotopes","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D003094","descriptor_name":"Collagen","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D005269","descriptor_name":"Femur","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D006041","descriptor_name":"Goats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009587","descriptor_name":"Nitrogen Isotopes","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D019906","descriptor_name":"Nuclear Magnetic Resonance, Biomolecular","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1002/mrc.5084","doi":"https://doi.org/10.1002/mrc.5084","is_oa":false,"landing_page_url":"https://doi.org/10.1002/mrc.5084","pdf_url":null,"source":{"id":"https://openalex.org/S112856106","display_name":"Magnetic Resonance in Chemistry","issn_l":"0749-1581","issn":["0749-1581","1097-458X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","poland-40","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Magnetic Resonance in Chemistry","raw_type":"journal-article"},{"id":"pmid:32761649","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/32761649","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Magnetic resonance in chemistry : MRC","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G4351231198","display_name":null,"funder_award_id":"EMR/2015/001758","funder_id":"https://openalex.org/F4320334771","funder_display_name":"Science and Engineering Research Board"}],"funders":[{"id":"https://openalex.org/F4320320721","display_name":"Council of Scientific and Industrial Research, India","ror":"https://ror.org/021wm7p51"},{"id":"https://openalex.org/F4320326265","display_name":"Department of Science and Technology, Government of Rajasthan","ror":"https://ror.org/000830238"},{"id":"https://openalex.org/F4320334771","display_name":"Science and Engineering Research Board","ror":"https://ror.org/03ffdsr55"},{"id":"https://openalex.org/F4320335900","display_name":"Central Mechanical Engineering Research Institute, Council of Scientific and Industrial Research","ror":"https://ror.org/059h0ng81"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":59,"referenced_works":["https://openalex.org/W1004084475","https://openalex.org/W1550291872","https://openalex.org/W1780562153","https://openalex.org/W1859455489","https://openalex.org/W1964556609","https://openalex.org/W1972668553","https://openalex.org/W1972985696","https://openalex.org/W1974390195","https://openalex.org/W1977612780","https://openalex.org/W1977671514","https://openalex.org/W1978304114","https://openalex.org/W1979221090","https://openalex.org/W1990881265","https://openalex.org/W1995359060","https://openalex.org/W1998346337","https://openalex.org/W2001803547","https://openalex.org/W2010127700","https://openalex.org/W2030163251","https://openalex.org/W2030530702","https://openalex.org/W2031303046","https://openalex.org/W2033343514","https://openalex.org/W2035066110","https://openalex.org/W2035202005","https://openalex.org/W2035812458","https://openalex.org/W2040025224","https://openalex.org/W2045265652","https://openalex.org/W2045729802","https://openalex.org/W2055516309","https://openalex.org/W2056742288","https://openalex.org/W2058086253","https://openalex.org/W2072632819","https://openalex.org/W2077559513","https://openalex.org/W2092362745","https://openalex.org/W2102719653","https://openalex.org/W2108379536","https://openalex.org/W2119803124","https://openalex.org/W2130971715","https://openalex.org/W2141871922","https://openalex.org/W2151910255","https://openalex.org/W2154918056","https://openalex.org/W2158407702","https://openalex.org/W2161162374","https://openalex.org/W2282370358","https://openalex.org/W2313135948","https://openalex.org/W2323466093","https://openalex.org/W2332149020","https://openalex.org/W2333116175","https://openalex.org/W2339663800","https://openalex.org/W2599668542","https://openalex.org/W2623184257","https://openalex.org/W2738810944","https://openalex.org/W2801435489","https://openalex.org/W2954701605","https://openalex.org/W2966841571","https://openalex.org/W2970871127","https://openalex.org/W2996950566","https://openalex.org/W3020071295","https://openalex.org/W4237414192","https://openalex.org/W7097432222"],"related_works":["https://openalex.org/W2323466093","https://openalex.org/W4405973314","https://openalex.org/W4417149689","https://openalex.org/W2593352035","https://openalex.org/W3158011422","https://openalex.org/W1004084475","https://openalex.org/W1490271381","https://openalex.org/W2012530985","https://openalex.org/W2035202005","https://openalex.org/W2000309399"],"abstract_inverted_index":{"Abstract":[0],"Solid\u2010state":[1],"nuclear":[2,43],"magnetic":[3,44],"resonance":[4,45],"is":[5],"a":[6,77,133],"promising":[7],"technique":[8],"to":[9,30,54,107,137,168],"probe":[10],"bone":[11],"mineralization":[12],"and":[13,118,153],"interaction":[14],"of":[15,24,34,64,100,129,156,165],"collagen":[16,65,131,158],"protein":[17,66],"in":[18,67,81,149],"the":[19,25,31,35,49,60,71,82,90,98,163,166],"native":[20,68,130,157],"state.":[21],"However,":[22],"many":[23],"developments":[26],"are":[27],"hampered":[28],"due":[29],"low":[32],"sensitivity":[33,79,101],"technique.":[36],"In":[37],"this":[38],"article,":[39],"we":[40,103],"report":[41,74],"solid\u2010state":[42,94],"(NMR)":[46],"experiments":[47,128,146],"using":[48],"newly":[50],"developed":[51],"BioSolids":[52],"CryoProbe\u2122":[53],"access":[55],"its":[56],"applicability":[57],"for":[58],"elucidating":[59],"atomic\u2010level":[61],"structural":[62],"details":[63],"state":[69],"inside":[70],"bone.":[72],"We":[73],"here":[75],"approximately":[76],"fourfold":[78],"enhancement":[80],"natural":[83,109],"abundance":[84,110],"13":[85,123,143],"C":[86,124,144],"spectrum":[87],"compared":[88],"with":[89],"room":[91],"temperature":[92],"conventional":[93],"NMR":[95],"probe.":[96],"With":[97],"advantage":[99],"enhancement,":[102],"have":[104,147],"been":[105],"able":[106],"perform":[108],"15":[111],"N":[112],"cross\u2010polarization":[113],"magic":[114],"angle":[115],"spinning":[116],"(CPMAS)":[117],"two\u2010dimensional":[119],"(2D)":[120],"1":[121,141],"H\u2013":[122],"heteronuclear":[125],"correlation":[126],"(HETCOR)":[127],"within":[132],"reasonable":[134],"timeframe.":[135],"Due":[136],"high":[138],"sensitivity,":[139],"2D":[140],"H/":[142],"HETCOR":[145],"helped":[148],"detecting":[150],"several":[151],"short":[152],"long\u2010range":[154],"interactions":[155],"assembly,":[159],"thus":[160],"significantly":[161],"expanding":[162],"scope":[164],"method":[167],"such":[169],"challenging":[170],"biomaterials.":[171]},"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":2},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":4},{"year":2021,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2020-08-13T00:00:00"}