{"id":"https://openalex.org/W3047287486","doi":"https://doi.org/10.1021/acs.jmedchem.0c00617","title":"Ultrabright and Serum-Stable Squaraine Dyes","display_name":"Ultrabright and Serum-Stable Squaraine Dyes","publication_year":2020,"publication_date":"2020-08-04","ids":{"openalex":"https://openalex.org/W3047287486","doi":"https://doi.org/10.1021/acs.jmedchem.0c00617","mag":"3047287486","pmid":"https://pubmed.ncbi.nlm.nih.gov/32787096","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/8428814"},"language":"en","primary_location":{"id":"doi:10.1021/acs.jmedchem.0c00617","doi":"https://doi.org/10.1021/acs.jmedchem.0c00617","is_oa":false,"landing_page_url":"https://doi.org/10.1021/acs.jmedchem.0c00617","pdf_url":null,"source":{"id":"https://openalex.org/S162030435","display_name":"Journal of Medicinal Chemistry","issn_l":"0022-2623","issn":["0022-2623","1520-4804"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","jufo-3","ki-jl-2","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Medicinal Chemistry","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://europepmc.org/pmc/articles/PMC8428814","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5042197347","display_name":"Yogesh Yadav","orcid":"https://orcid.org/0000-0001-6431-7021","observed_orcids":["https://orcid.org/0000-0001-6431-7021"]},"institutions":[{"id":"https://openalex.org/I181565077","display_name":"Georgia State University","ror":"https://ror.org/03qt6ba18","country_code":"US","type":"education","lineage":["https://openalex.org/I181565077"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Yogesh Yadav","raw_affiliation_strings":["Department of Chemistry, Georgia State University, 145 Piedmont Avenue SE, Atlanta, Georgia 30303, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, Georgia State University, 145 Piedmont Avenue SE, Atlanta, Georgia 30303, United States","institution_ids":["https://openalex.org/I181565077"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069877227","display_name":"Eric A. Owens","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I181565077","display_name":"Georgia State University","ror":"https://ror.org/03qt6ba18","country_code":"US","type":"education","lineage":["https://openalex.org/I181565077"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Eric Owens","raw_affiliation_strings":["Center for Diagnostics and Therapeutics, 145 Piedmont Avenue SE, Atlanta, Georgia 30303, United States","Department of Chemistry, Georgia State University, 145 Piedmont Avenue SE, Atlanta, Georgia 30303, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Diagnostics and Therapeutics, 145 Piedmont Avenue SE, Atlanta, Georgia 30303, United States","institution_ids":[]},{"raw_affiliation_string":"Department of Chemistry, Georgia State University, 145 Piedmont Avenue SE, Atlanta, Georgia 30303, United States","institution_ids":["https://openalex.org/I181565077"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Shinsuke Nomura","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210087193","display_name":"National Defense Medical College Hospital","ror":"https://ror.org/004ej3g52","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210087193"]},{"id":"https://openalex.org/I4210087356","display_name":"Gordon Center for Medical Imaging","ror":"https://ror.org/004y4rj95","country_code":"US","type":"facility","lineage":["https://openalex.org/I136199984","https://openalex.org/I4210087356","https://openalex.org/I4210087915","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I53888640","display_name":"National Defense Medical College","ror":"https://ror.org/02e4qbj88","country_code":"JP","type":"education","lineage":["https://openalex.org/I53888640"]}],"countries":["JP","US"],"is_corresponding":false,"raw_author_name":"Shinsuke Nomura","raw_affiliation_strings":["Department of Surgery, National Defense Medical College, Tokorozawa, Saitama 359-8513, Japan","Gordon Center for Medical Imaging, Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Surgery, National Defense Medical College, Tokorozawa, Saitama 359-8513, Japan","institution_ids":["https://openalex.org/I4210087193","https://openalex.org/I53888640"]},{"raw_affiliation_string":"Gordon Center for Medical Imaging, Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114, United States","institution_ids":["https://openalex.org/I136199984","https://openalex.org/I4210087356","https://openalex.org/I4210087915"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101405006","display_name":"Takeshi Fukuda","orcid":"https://orcid.org/0000-0003-4848-4078","observed_orcids":["https://orcid.org/0000-0003-4848-4078"]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210087356","display_name":"Gordon Center for Medical Imaging","ror":"https://ror.org/004y4rj95","country_code":"US","type":"facility","lineage":["https://openalex.org/I136199984","https://openalex.org/I4210087356","https://openalex.org/I4210087915","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Takeshi Fukuda","raw_affiliation_strings":["Gordon Center for Medical Imaging, Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Gordon Center for Medical Imaging, Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114, United States","institution_ids":["https://openalex.org/I136199984","https://openalex.org/I4210087356","https://openalex.org/I4210087915"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029239155","display_name":"Yoonji Baek","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210087356","display_name":"Gordon Center for Medical Imaging","ror":"https://ror.org/004y4rj95","country_code":"US","type":"facility","lineage":["https://openalex.org/I136199984","https://openalex.org/I4210087356","https://openalex.org/I4210087915","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Yoonji Baek","raw_affiliation_strings":["Gordon Center for Medical Imaging, Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Gordon Center for Medical Imaging, Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114, United States","institution_ids":["https://openalex.org/I136199984","https://openalex.org/I4210087356","https://openalex.org/I4210087915"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039744313","display_name":"Satoshi Kashiwagi","orcid":"https://orcid.org/0000-0001-8910-3257","observed_orcids":["https://orcid.org/0000-0001-8910-3257"]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210087356","display_name":"Gordon Center for Medical Imaging","ror":"https://ror.org/004y4rj95","country_code":"US","type":"facility","lineage":["https://openalex.org/I136199984","https://openalex.org/I4210087356","https://openalex.org/I4210087915","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Satoshi Kashiwagi","raw_affiliation_strings":["Gordon Center for Medical Imaging, Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Gordon Center for Medical Imaging, Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114, United States","institution_ids":["https://openalex.org/I136199984","https://openalex.org/I4210087356","https://openalex.org/I4210087915"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081241283","display_name":"Hak Soo Choi","orcid":"https://orcid.org/0000-0002-7982-6483","observed_orcids":["https://orcid.org/0000-0002-7982-6483","https://orcid.org/0000-0003-0764-1567"]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210087356","display_name":"Gordon Center for Medical Imaging","ror":"https://ror.org/004y4rj95","country_code":"US","type":"facility","lineage":["https://openalex.org/I136199984","https://openalex.org/I4210087356","https://openalex.org/I4210087915","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Hak Soo Choi","raw_affiliation_strings":["Gordon Center for Medical Imaging, Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114, United States"],"raw_orcid":"https://orcid.org/0000-0002-7982-6483","affiliations":[{"raw_affiliation_string":"Gordon Center for Medical Imaging, Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114, United States","institution_ids":["https://openalex.org/I136199984","https://openalex.org/I4210087356","https://openalex.org/I4210087915"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5004953257","display_name":"Maged Henary","orcid":"https://orcid.org/0000-0002-6475-0156","observed_orcids":["https://orcid.org/0000-0002-6475-0156"]},"institutions":[{"id":"https://openalex.org/I181565077","display_name":"Georgia State University","ror":"https://ror.org/03qt6ba18","country_code":"US","type":"education","lineage":["https://openalex.org/I181565077"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Maged Henary","raw_affiliation_strings":["Center for Diagnostics and Therapeutics, 145 Piedmont Avenue SE, Atlanta, Georgia 30303, United States","Department of Chemistry, Georgia State University, 145 Piedmont Avenue SE, Atlanta, Georgia 30303, United States"],"raw_orcid":"https://orcid.org/0000-0002-6475-0156","affiliations":[{"raw_affiliation_string":"Center for Diagnostics and Therapeutics, 145 Piedmont Avenue SE, Atlanta, Georgia 30303, United States","institution_ids":[]},{"raw_affiliation_string":"Department of Chemistry, Georgia State University, 145 Piedmont Avenue SE, Atlanta, Georgia 30303, United States","institution_ids":["https://openalex.org/I181565077"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5004953257","https://openalex.org/A5081241283"],"corresponding_institution_ids":["https://openalex.org/I136199984","https://openalex.org/I181565077","https://openalex.org/I4210087356","https://openalex.org/I4210087915"],"apc_list":{"value":5000,"currency":"USD","value_usd":5000},"apc_paid":null,"fwci":1.0577,"has_fulltext":false,"cited_by_count":29,"citation_normalized_percentile":{"value":0.73523188,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"63","issue":"17","first_page":"9436","last_page":"9445"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11240","display_name":"Luminescence and Fluorescent Materials","score":0.7275000214576721,"subfield":{"id":"https://openalex.org/subfields/2505","display_name":"Materials Chemistry"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T11240","display_name":"Luminescence and Fluorescent Materials","score":0.7275000214576721,"subfield":{"id":"https://openalex.org/subfields/2505","display_name":"Materials Chemistry"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10532","display_name":"Molecular Sensors and Ion Detection","score":0.23409999907016754,"subfield":{"id":"https://openalex.org/subfields/1607","display_name":"Spectroscopy"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11129","display_name":"Photochemistry and Electron Transfer Studies","score":0.02759999968111515,"subfield":{"id":"https://openalex.org/subfields/1606","display_name":"Physical and Theoretical Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/squaraine-dyes","display_name":"squaraine dyes","score":0.9890000224113464},{"id":"https://openalex.org/keywords/fluorophores","display_name":"fluorophores","score":0.7730000019073486},{"id":"https://openalex.org/keywords/quaternary-ammonium-cations","display_name":"quaternary ammonium cations","score":0.9750000238418579},{"id":"https://openalex.org/keywords/serum-stability","display_name":"serum stability","score":0.8140000104904175},{"id":"https://openalex.org/keywords/thermal-stability","display_name":"thermal stability","score":0.7170000076293945},{"id":"https://openalex.org/keywords/photostability","display_name":"photostability","score":0.9430000185966492},{"id":"https://openalex.org/keywords/quantum-yield","display_name":"quantum yield","score":0.6710000038146973},{"id":"https://openalex.org/keywords/fluorescent-sensing","display_name":"fluorescence sensing","score":0.9049999713897705},{"id":"https://openalex.org/keywords/biological-tagging","display_name":"biological tagging","score":0.5759999752044678}],"concepts":[{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.8979698419570923},{"id":"https://openalex.org/C192468462","wikidata":"https://www.wikidata.org/wiki/Q533543","display_name":"Chromophore","level":2,"score":0.8595312833786011},{"id":"https://openalex.org/C171001562","wikidata":"https://www.wikidata.org/wiki/Q2856048","display_name":"Quantum yield","level":3,"score":0.759350061416626},{"id":"https://openalex.org/C2778617687","wikidata":"https://www.wikidata.org/wiki/Q2448456","display_name":"Fluorophore","level":3,"score":0.7479479908943176},{"id":"https://openalex.org/C91881484","wikidata":"https://www.wikidata.org/wiki/Q191807","display_name":"Fluorescence","level":2,"score":0.6746954917907715},{"id":"https://openalex.org/C75473681","wikidata":"https://www.wikidata.org/wiki/Q188651","display_name":"Photochemistry","level":1,"score":0.6539159417152405},{"id":"https://openalex.org/C59061564","wikidata":"https://www.wikidata.org/wiki/Q7783071","display_name":"Thermal stability","level":2,"score":0.5927906632423401},{"id":"https://openalex.org/C180577832","wikidata":"https://www.wikidata.org/wiki/Q127920","display_name":"Covalent bond","level":2,"score":0.544772744178772},{"id":"https://openalex.org/C112613896","wikidata":"https://www.wikidata.org/wiki/Q898370","display_name":"Conjugated system","level":3,"score":0.5075589418411255},{"id":"https://openalex.org/C76046532","wikidata":"https://www.wikidata.org/wiki/Q900239","display_name":"Molar absorptivity","level":2,"score":0.48165690898895264},{"id":"https://openalex.org/C2776371256","wikidata":"https://www.wikidata.org/wiki/Q12370","display_name":"Salt (chemistry)","level":2,"score":0.452311247587204},{"id":"https://openalex.org/C2779884411","wikidata":"https://www.wikidata.org/wiki/Q4914995","display_name":"Biological imaging","level":3,"score":0.4346780776977539},{"id":"https://openalex.org/C21951064","wikidata":"https://www.wikidata.org/wiki/Q899212","display_name":"Combinatorial chemistry","level":1,"score":0.4059382677078247},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.20339339971542358},{"id":"https://openalex.org/C521977710","wikidata":"https://www.wikidata.org/wiki/Q81163","display_name":"Polymer","level":2,"score":0.10605743527412415},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.0},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003503","descriptor_name":"Cyclobutanes","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D003503","descriptor_name":"Cyclobutanes","qualifier_ui":"Q000493","qualifier_name":"pharmacokinetics","is_major_topic":false},{"descriptor_ui":"D003503","descriptor_name":"Cyclobutanes","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D005456","descriptor_name":"Fluorescent Dyes","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D005456","descriptor_name":"Fluorescent Dyes","qualifier_ui":"Q000493","qualifier_name":"pharmacokinetics","is_major_topic":false},{"descriptor_ui":"D005456","descriptor_name":"Fluorescent Dyes","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D008958","descriptor_name":"Models, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008968","descriptor_name":"Molecular Conformation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010636","descriptor_name":"Phenols","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D010636","descriptor_name":"Phenols","qualifier_ui":"Q000493","qualifier_name":"pharmacokinetics","is_major_topic":false},{"descriptor_ui":"D010636","descriptor_name":"Phenols","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D014018","descriptor_name":"Tissue Distribution","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D044967","descriptor_name":"Serum","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1021/acs.jmedchem.0c00617","doi":"https://doi.org/10.1021/acs.jmedchem.0c00617","is_oa":false,"landing_page_url":"https://doi.org/10.1021/acs.jmedchem.0c00617","pdf_url":null,"source":{"id":"https://openalex.org/S162030435","display_name":"Journal of Medicinal Chemistry","issn_l":"0022-2623","issn":["0022-2623","1520-4804"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","jufo-3","ki-jl-2","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Medicinal Chemistry","raw_type":"journal-article"},{"id":"pmid:32787096","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/32787096","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of medicinal chemistry","raw_type":"Journal Article"},{"id":"pmh:oai:europepmc.org:7322675","doi":null,"is_oa":true,"landing_page_url":"http://europepmc.org/pmc/articles/PMC8428814","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"","raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:8428814","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/8428814","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"J Med Chem","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:europepmc.org:7322675","doi":null,"is_oa":true,"landing_page_url":"http://europepmc.org/pmc/articles/PMC8428814","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"","raw_type":"Text"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G8946656671","display_name":"Image-Guided Drug Delivery for Pancreatic Neuroendocrine Tumor.","funder_award_id":"R01EB022230","funder_id":"https://openalex.org/F4320337363","funder_display_name":"National Institute of Biomedical Imaging and Bioengineering"}],"funders":[{"id":"https://openalex.org/F4320310607","display_name":"Georgia State University","ror":"https://ror.org/03qt6ba18"},{"id":"https://openalex.org/F4320337363","display_name":"National Institute of Biomedical Imaging and Bioengineering","ror":"https://ror.org/00372qc85"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":22,"referenced_works":["https://openalex.org/W1972274306","https://openalex.org/W1973921444","https://openalex.org/W1974141993","https://openalex.org/W1985718130","https://openalex.org/W1991939740","https://openalex.org/W2025729551","https://openalex.org/W2052682656","https://openalex.org/W2056283385","https://openalex.org/W2082449297","https://openalex.org/W2088483106","https://openalex.org/W2092467432","https://openalex.org/W2100796654","https://openalex.org/W2108763092","https://openalex.org/W2117315288","https://openalex.org/W2121803450","https://openalex.org/W2123061071","https://openalex.org/W2128780255","https://openalex.org/W2170959394","https://openalex.org/W2320328964","https://openalex.org/W2323643267","https://openalex.org/W2437233911","https://openalex.org/W2966228955"],"related_works":["https://openalex.org/W2066402087","https://openalex.org/W4280548852","https://openalex.org/W1966879506","https://openalex.org/W2060518352","https://openalex.org/W4249985642","https://openalex.org/W127692157","https://openalex.org/W6917754071","https://openalex.org/W2078423254","https://openalex.org/W2001105299","https://openalex.org/W2066232007"],"abstract_inverted_index":{"Highly":[0],"stable":[1],"symmetric":[2,33],"and":[3,20,34,45,70],"asymmetric":[4,35],"squaraine":[5,64],"fluorophores":[6],"have":[7],"been":[8],"synthesized":[9,32],"featuring":[10],"an":[11],"internal":[12],"salt":[13],"bridge":[14],"between":[15],"a":[16,77],"quaternary":[17],"ammonium":[18],"cation":[19],"the":[21,26,61,83,93,98],"central":[22],"oxycyclobutenolate":[23],"ring":[24],"of":[25,29,97],"chromophore.":[27],"Some":[28],"our":[30],"newly":[31,99],"compounds":[36],"display":[37],"increased":[38],"molar":[39],"absorptivity,":[40],"quantum":[41],"yield":[42],"in":[43,59],"serum,":[44],"thermal/photochemical":[46],"stability":[47],"over":[48],"previously":[49],"reported":[50],"squaraine-based":[51],"dyes.":[52],"Consequently,":[53],"both":[54],"classes":[55],"show":[56],"great":[57],"promise":[58],"resurfacing":[60],"normal":[62],"environment-labile":[63],"dyes":[65],"as":[66],"novel":[67],"imaging":[68],"agents":[69],"scaffolds":[71],"for":[72,87],"fluorescence":[73],"sensing.":[74],"Furthermore,":[75],"incorporating":[76],"covalent":[78],"attachment":[79],"point":[80],"away":[81],"from":[82],"conjugated":[84],"system":[85],"allows":[86],"biological":[88],"tagging":[89],"applications":[90],"without":[91],"disturbing":[92],"optimum":[94],"optical":[95],"characteristics":[96],"designed":[100],"fluorophore.":[101]},"counts_by_year":[{"year":2026,"cited_by_count":6},{"year":2025,"cited_by_count":4},{"year":2024,"cited_by_count":8},{"year":2023,"cited_by_count":6},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2020-08-10T00:00:00"}