{"id":"https://openalex.org/W3046913541","doi":"https://doi.org/10.1186/s43168-020-00014-1","title":"Arterial stiffness can occur early in mild-to-moderate chronic obstructive pulmonary disease","display_name":"Arterial stiffness can occur early in mild-to-moderate chronic obstructive pulmonary disease","publication_year":2020,"publication_date":"2020-07-30","ids":{"openalex":"https://openalex.org/W3046913541","doi":"https://doi.org/10.1186/s43168-020-00014-1","mag":"3046913541"},"language":"en","primary_location":{"id":"doi:10.1186/s43168-020-00014-1","doi":"https://doi.org/10.1186/s43168-020-00014-1","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s43168-020-00014-1","pdf_url":"https://ejb.springeropen.com/counter/pdf/10.1186/s43168-020-00014-1","source":{"id":"https://openalex.org/S2764714012","display_name":"Egyptian Journal of Bronchology","issn_l":"1687-8426","issn":["1687-8426","2314-8551"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["doaj","poland-20","russia-white-list-4"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Egyptian Journal of Bronchology","raw_type":"journal-article"},"parent_works":[],"lineage":["https://openalex.org/W3046913541"],"child_works_count":0,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://ejb.springeropen.com/counter/pdf/10.1186/s43168-020-00014-1","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5083573653","display_name":"Waleed Mansour","orcid":"https://orcid.org/0000-0001-9115-2197","observed_orcids":["https://orcid.org/0000-0001-9115-2197"]},"institutions":[{"id":"https://openalex.org/I192398990","display_name":"Zagazig University","ror":"https://ror.org/053g6we49","country_code":"EG","type":"education","lineage":["https://openalex.org/I192398990"]}],"countries":["EG"],"is_corresponding":false,"raw_author_name":"Waleed Mansour","raw_affiliation_strings":["Pulmonary Medicine Department, Zagazig Faculty of Medicine, Zagazig, Egypt"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Pulmonary Medicine Department, Zagazig Faculty of Medicine, Zagazig, Egypt","institution_ids":["https://openalex.org/I192398990"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074142448","display_name":"Mohamed El-Shabrawy","orcid":"https://orcid.org/0000-0002-3720-7959","observed_orcids":["https://orcid.org/0000-0002-3720-7959"]},"institutions":[{"id":"https://openalex.org/I192398990","display_name":"Zagazig University","ror":"https://ror.org/053g6we49","country_code":"EG","type":"education","lineage":["https://openalex.org/I192398990"]}],"countries":["EG"],"is_corresponding":false,"raw_author_name":"Mohamed El-Shabrawy","raw_affiliation_strings":["Pulmonary Medicine Department, Zagazig Faculty of Medicine, Zagazig, Egypt"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Pulmonary Medicine Department, Zagazig Faculty of Medicine, Zagazig, Egypt","institution_ids":["https://openalex.org/I192398990"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101722895","display_name":"Wael Ali Khalil","orcid":"https://orcid.org/0000-0002-7296-092X","observed_orcids":["https://orcid.org/0000-0002-7296-092X"]},"institutions":[{"id":"https://openalex.org/I192398990","display_name":"Zagazig University","ror":"https://ror.org/053g6we49","country_code":"EG","type":"education","lineage":["https://openalex.org/I192398990"]}],"countries":["EG"],"is_corresponding":false,"raw_author_name":"Wael A. Khalil","raw_affiliation_strings":["Cardiology Department, Zagazig Faculty of Medicine, Zagazig, Egypt"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cardiology Department, Zagazig Faculty of Medicine, Zagazig, Egypt","institution_ids":["https://openalex.org/I192398990"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082494971","display_name":"Ahmed Eldamanhory","orcid":"https://orcid.org/0000-0001-5001-6295","observed_orcids":["https://orcid.org/0000-0001-5001-6295"]},"institutions":[{"id":"https://openalex.org/I192398990","display_name":"Zagazig University","ror":"https://ror.org/053g6we49","country_code":"EG","type":"education","lineage":["https://openalex.org/I192398990"]}],"countries":["EG"],"is_corresponding":false,"raw_author_name":"Ahmad S. Eldamanhory","raw_affiliation_strings":["Cardiology Department, Zagazig Faculty of Medicine, Zagazig, Egypt"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cardiology Department, Zagazig Faculty of Medicine, Zagazig, Egypt","institution_ids":["https://openalex.org/I192398990"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5009450887","display_name":"Sameh Embarak","orcid":"https://orcid.org/0000-0001-9046-675X","observed_orcids":["https://orcid.org/0000-0001-9046-675X"]},"institutions":[{"id":"https://openalex.org/I192398990","display_name":"Zagazig University","ror":"https://ror.org/053g6we49","country_code":"EG","type":"education","lineage":["https://openalex.org/I192398990"]}],"countries":["EG"],"is_corresponding":true,"raw_author_name":"Sameh Embarak","raw_affiliation_strings":["Pulmonary Medicine Department, Zagazig Faculty of Medicine, Zagazig, Egypt"],"raw_orcid":"https://orcid.org/0000-0001-9046-675X","affiliations":[{"raw_affiliation_string":"Pulmonary Medicine Department, Zagazig Faculty of Medicine, Zagazig, Egypt","institution_ids":["https://openalex.org/I192398990"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5009450887"],"corresponding_institution_ids":["https://openalex.org/I192398990"],"apc_list":{"value":0,"currency":"USD","value_usd":0},"apc_paid":null,"fwci":0.1619,"has_fulltext":true,"cited_by_count":2,"citation_normalized_percentile":{"value":0.45988006,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":95},"biblio":{"volume":"14","issue":"1","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10924","display_name":"Cardiovascular Health and Disease Prevention","score":0.8809000253677368,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10924","display_name":"Cardiovascular Health and Disease Prevention","score":0.8809000253677368,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10143","display_name":"Chronic Obstructive Pulmonary Disease (COPD) Research","score":0.1143999993801117,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10728","display_name":"Pulmonary Hypertension Research and Treatments","score":0.0010999999940395355,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/arterial-stiffness","display_name":"arterial stiffness","score":0.8240000009536743},{"id":"https://openalex.org/keywords/chronic-obstructive-pulmonary-disease","display_name":"chronic obstructive pulmonary disease","score":0.9990000128746033},{"id":"https://openalex.org/keywords/carotid-femoral-pulse-wave-velocity","display_name":"carotid-femoral pulse wave velocity","score":0.8989999890327454},{"id":"https://openalex.org/keywords/augmentation-index","display_name":"augmentation index","score":0.9760000109672546},{"id":"https://openalex.org/keywords/cardiovascular-risk","display_name":"cardiovascular risk","score":0.7009999752044678},{"id":"https://openalex.org/keywords/bode-index","display_name":"BODE index","score":0.8529999852180481},{"id":"https://openalex.org/keywords/fev1","display_name":"FEV1","score":0.9359999895095825},{"id":"https://openalex.org/keywords/mild-to-moderate-copd","display_name":"mild to moderate COPD","score":0.8840000033378601}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9132330417633057},{"id":"https://openalex.org/C2776780178","wikidata":"https://www.wikidata.org/wiki/Q199804","display_name":"COPD","level":2,"score":0.8831682205200195},{"id":"https://openalex.org/C2775850156","wikidata":"https://www.wikidata.org/wiki/Q4797538","display_name":"Arterial stiffness","level":3,"score":0.7950564622879028},{"id":"https://openalex.org/C2778319312","wikidata":"https://www.wikidata.org/wiki/Q2118022","display_name":"Pulse wave velocity","level":3,"score":0.7745953798294067},{"id":"https://openalex.org/C2777168814","wikidata":"https://www.wikidata.org/wiki/Q16246543","display_name":"BODE index","level":4,"score":0.7679409980773926},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.7617613077163696},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.7147328853607178},{"id":"https://openalex.org/C113280763","wikidata":"https://www.wikidata.org/wiki/Q2326546","display_name":"Subclinical infection","level":2,"score":0.5898723602294922},{"id":"https://openalex.org/C2780221984","wikidata":"https://www.wikidata.org/wiki/Q131191","display_name":"Body mass index","level":2,"score":0.5276573896408081},{"id":"https://openalex.org/C2992779976","wikidata":"https://www.wikidata.org/wiki/Q3286546","display_name":"Pulmonary disease","level":2,"score":0.47086015343666077},{"id":"https://openalex.org/C84393581","wikidata":"https://www.wikidata.org/wiki/Q82642","display_name":"Blood pressure","level":2,"score":0.2731190323829651},{"id":"https://openalex.org/C2780779891","wikidata":"https://www.wikidata.org/wiki/Q3455927","display_name":"Pulmonary rehabilitation","level":3,"score":0.20257624983787537}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1186/s43168-020-00014-1","doi":"https://doi.org/10.1186/s43168-020-00014-1","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s43168-020-00014-1","pdf_url":"https://ejb.springeropen.com/counter/pdf/10.1186/s43168-020-00014-1","source":{"id":"https://openalex.org/S2764714012","display_name":"Egyptian Journal of Bronchology","issn_l":"1687-8426","issn":["1687-8426","2314-8551"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["doaj","poland-20","russia-white-list-4"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Egyptian Journal of Bronchology","raw_type":"journal-article"},{"id":"pmh:oai:doaj.org/article:42d525926264495495f504d59af4198f","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/42d525926264495495f504d59af4198f","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"The Egyptian Journal of Bronchology, Vol 14, Iss 1, Pp 1-6 (2020)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1186/s43168-020-00014-1","doi":"https://doi.org/10.1186/s43168-020-00014-1","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s43168-020-00014-1","pdf_url":"https://ejb.springeropen.com/counter/pdf/10.1186/s43168-020-00014-1","source":{"id":"https://openalex.org/S2764714012","display_name":"Egyptian Journal of Bronchology","issn_l":"1687-8426","issn":["1687-8426","2314-8551"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["doaj","poland-20","russia-white-list-4"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Egyptian Journal of Bronchology","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":1.0}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3046913541.pdf","grobid_xml":"https://content.openalex.org/works/W3046913541.grobid-xml"},"referenced_works_count":24,"referenced_works":["https://openalex.org/W1987138414","https://openalex.org/W2025994623","https://openalex.org/W2029473249","https://openalex.org/W2043386134","https://openalex.org/W2049759474","https://openalex.org/W2063998910","https://openalex.org/W2067222353","https://openalex.org/W2077499565","https://openalex.org/W2102293088","https://openalex.org/W2104842795","https://openalex.org/W2110635468","https://openalex.org/W2114423036","https://openalex.org/W2122573318","https://openalex.org/W2132683688","https://openalex.org/W2133968040","https://openalex.org/W2139347600","https://openalex.org/W2139503178","https://openalex.org/W2144120465","https://openalex.org/W2153743722","https://openalex.org/W2159928915","https://openalex.org/W2583265473","https://openalex.org/W2963847237","https://openalex.org/W3002792698","https://openalex.org/W4245666729"],"related_works":["https://openalex.org/W2093680549","https://openalex.org/W2133968040","https://openalex.org/W2062310019","https://openalex.org/W3176568283","https://openalex.org/W2049759474","https://openalex.org/W4309455555","https://openalex.org/W2077981375","https://openalex.org/W4255606947","https://openalex.org/W2412164016","https://openalex.org/W3032775058"],"abstract_inverted_index":{"Abstract":[0],"Background":[1],"Chronic":[2],"obstructive":[3],"pulmonary":[4],"disease":[5],"(COPD)":[6],"is":[7],"a":[8],"well-known":[9],"respiratory":[10],"system":[11],"disorder":[12],"impacting":[13],"patient\u2019s":[14],"morbidity":[15],"and":[16,71,82,97,115,145,162,177,194,202],"mortality.":[17],"Many":[18],"COPD":[19,38,60,69,105],"patients":[20,70,106,186,206],"die":[21],"from":[22],"cardiovascular":[23,35],"diseases.":[24],"Criteria":[25],"of":[26,47,131,200],"arterial":[27,48],"stiffness":[28,49],"might":[29],"be":[30],"the":[31,45,83],"early":[32,52],"clue":[33],"for":[34],"affection":[36],"in":[37,55,127,185,205],"patients.":[39,61],"This":[40,63],"study":[41,65],"aimed":[42],"to":[43,58,109],"evaluate":[44],"occurrence":[46],"as":[50],"an":[51],"subclinical":[53],"change":[54],"stable":[56],"mild":[57],"moderate":[59],"Results":[62],"cross-sectional":[64],"included":[66],"80":[67,73],"mild-to-moderate":[68,104,188,208],"another":[72],"healthy":[74,110],"controls.":[75],"The":[76],"carotid-femoral":[77],"pulse":[78],"wave":[79,192],"velocity":[80,193],"(cf-PWV)":[81],"heart":[84],"rate":[85],"adjusted":[86],"augmentation":[87,195],"index":[88,165,196,204],"(AIx75)":[89],"were":[90],"statistically":[91],"significantly":[92],"higher":[93],"(13.8":[94],"\u00b1":[95,99,113,117],"2.6":[96],"23.9":[98],"10.8,":[100],"respectively)":[101,119],"among":[102],"studied":[103],"when":[107],"compared":[108],"controls":[111],"(10.7":[112],"1.1":[114],"18.1":[116],"8.9,":[118],"(p":[120],"<":[121,143,152,175,183],"0.001).":[122],"FEV1":[123],"(forced":[124],"expiratory":[125],"volume":[126],"1":[128],"s)":[129],"%":[130],"predicted":[132,201],"correlated":[133,166,197],"negatively":[134],"with":[135,168,187,198,207],"both":[136,169],"AIx75":[137,170],"(r":[138,147,171,179],"=":[139,148,172,180],"\u2212":[140,149],"0.84,":[141],"p":[142,151,174,182],"0.001)":[144,176,184],"cf-PWV":[146,178],"0.85,":[150],"0.001),":[153],"while":[154],"BODE":[155,203],"(body":[156],"mass":[157],"index,":[158],"airflow":[159],"obstruction,":[160],"dyspnea,":[161],"exercise":[163],"capacity)":[164],"positively":[167],"0.58,":[173],"0.52,":[181],"COPD.":[189,209],"Conclusions":[190],"Pulse":[191],"FEV1%":[199]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2021,"cited_by_count":1}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2020-08-07T00:00:00"}