{"id":"https://openalex.org/W3046165221","doi":"https://doi.org/10.1201/9781003068174-3","title":"Alterations in the Steroidogenic Capacity of Leydig Cells in Cryptorchid Testis","display_name":"Alterations in the Steroidogenic Capacity of Leydig Cells in Cryptorchid Testis","publication_year":2020,"publication_date":"2020-07-28","ids":{"openalex":"https://openalex.org/W3046165221","doi":"https://doi.org/10.1201/9781003068174-3","mag":"3046165221"},"language":"en","primary_location":{"id":"doi:10.1201/9781003068174-3","doi":"https://doi.org/10.1201/9781003068174-3","is_oa":false,"landing_page_url":"https://doi.org/10.1201/9781003068174-3","pdf_url":null,"source":{"id":"https://openalex.org/S4306463075","display_name":"CRC Press eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310320584","host_organization_name":"CRC Press","host_organization_lineage":["https://openalex.org/P4310320584","https://openalex.org/P4310320547"],"host_organization_lineage_names":["CRC Press","Taylor & Francis"],"type":"ebook platform"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Cryptorchid Testis","raw_type":"book-chapter"},"volume":{"id":"https://openalex.org/W399203353","display_name":"The Cryptorchid Testis"},"type":"book-chapter","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5072629287","display_name":"Friedrich Jockenho\u0308vel","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Friedrich Jockenhovel","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5090807122","display_name":"Ronald S. Swerdloff","orcid":"https://orcid.org/0000-0001-6084-6604","observed_orcids":["https://orcid.org/0000-0001-6084-6604"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ronald S. Swerdloff","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":4,"citation_normalized_percentile":{"value":0.22920696,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":null,"issue":null,"first_page":"35","last_page":"54"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10116","display_name":"Sperm and Testicular Function","score":0.8109999895095825,"subfield":{"id":"https://openalex.org/subfields/2743","display_name":"Reproductive Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10116","display_name":"Sperm and Testicular Function","score":0.8109999895095825,"subfield":{"id":"https://openalex.org/subfields/2743","display_name":"Reproductive Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11956","display_name":"Sexual Differentiation and Disorders","score":0.09260000288486481,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11146","display_name":"Hormonal and reproductive studies","score":0.03139999881386757,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cryptorchidism","display_name":"cryptorchidism","score":0.9959999918937683},{"id":"https://openalex.org/keywords/leydig-cells","display_name":"Leydig cells","score":0.9879999756813049},{"id":"https://openalex.org/keywords/testicular-steroidogenesis","display_name":"testicular steroidogenesis","score":0.9449999928474426},{"id":"https://openalex.org/keywords/testosterone-secretion","display_name":"testosterone secretion","score":0.8370000123977661},{"id":"https://openalex.org/keywords/human-chorionic-gonadotropin-stimulation-test","display_name":"human chorionic gonadotropin stimulation test","score":0.8939999938011169},{"id":"https://openalex.org/keywords/male-infertility","display_name":"male infertility","score":0.7170000076293945},{"id":"https://openalex.org/keywords/puberty","display_name":"puberty","score":0.4569999873638153},{"id":"https://openalex.org/keywords/hypothalamic-pituitary-gonadal-axis","display_name":"hypothalamic-pituitary-gonadal axis","score":0.8629999756813049},{"id":"https://openalex.org/keywords/androgen-secretion","display_name":"androgen secretion","score":0.4309999942779541}],"concepts":[{"id":"https://openalex.org/C2777736315","wikidata":"https://www.wikidata.org/wiki/Q636846","display_name":"Leydig cell","level":4,"score":0.6838208436965942},{"id":"https://openalex.org/C16685009","wikidata":"https://www.wikidata.org/wiki/Q335057","display_name":"Andrology","level":1,"score":0.36217817664146423},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.35271111130714417},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.3330535292625427},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.26927775144577026},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.22755062580108643},{"id":"https://openalex.org/C71315377","wikidata":"https://www.wikidata.org/wiki/Q11364","display_name":"Hormone","level":2,"score":0.04779013991355896},{"id":"https://openalex.org/C2778575703","wikidata":"https://www.wikidata.org/wiki/Q50265477","display_name":"Luteinizing hormone","level":3,"score":0.04242068529129028}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1201/9781003068174-3","doi":"https://doi.org/10.1201/9781003068174-3","is_oa":false,"landing_page_url":"https://doi.org/10.1201/9781003068174-3","pdf_url":null,"source":{"id":"https://openalex.org/S4306463075","display_name":"CRC Press eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310320584","host_organization_name":"CRC Press","host_organization_lineage":["https://openalex.org/P4310320584","https://openalex.org/P4310320547"],"host_organization_lineage_names":["CRC Press","Taylor & Francis"],"type":"ebook platform"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Cryptorchid Testis","raw_type":"book-chapter"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.8371999859809875,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":1,"referenced_works":["https://openalex.org/W2015133341"],"related_works":["https://openalex.org/W2030088350","https://openalex.org/W2088365078","https://openalex.org/W2153806140","https://openalex.org/W2079270385","https://openalex.org/W1998693297","https://openalex.org/W2003463456","https://openalex.org/W2020445687","https://openalex.org/W2416848631","https://openalex.org/W2149283968","https://openalex.org/W48259134"],"abstract_inverted_index":{"Bilateral":[0],"cryptorchidism,":[1],"when":[2],"uncorrected":[3],"until":[4],"adulthood,":[5],"is":[6,94,104,125,138],"a":[7,64],"predictive":[8],"cause":[9],"of":[10,20,44,61,73,99,114],"male":[11],"factor":[12],"infertility.":[13],"In":[14],"contrast":[15],"to":[16,87,142],"the":[17,23,36,42,45,58,145],"obvious":[18],"effects":[19,27],"cryptorchidism":[21],"on":[22,28,38],"germinal":[24],"tubules,":[25],"its":[26],"testicular":[29,92],"steroidogenesis":[30,93],"remain":[31],"controversial.":[32],"This":[33,136],"chapter":[34],"presents":[35],"evidence":[37],"this":[39],"topic":[40],"in":[41,54,67,117],"framework":[43],"normal":[46,118],"steroidogenic":[47],"developmental":[48],"process.":[49],"Leydig":[50],"cell":[51],"stimulation":[52],"tests":[53],"cryptorchid":[55],"infants":[56],"within":[57],"1st":[59],"year":[60],"life":[62],"showed":[63],"tenfold":[65],"increase":[66,137],"testosterone":[68,100,116],"secretion,":[69],"after":[70],"intramuscular":[71],"injection":[72],"500":[74],"I.U.":[75],"human":[76],"chorionic":[77],"gonadotropin":[78,134],"every":[79],"other":[80,102],"day":[81],"for":[82],"6":[83,123],"d,":[84],"as":[85],"compared":[86],"basal":[88],"levels.":[89,135],"During":[90],"childhood,":[91],"at":[95,144],"rest":[96],"and":[97,101,107],"secretion":[98],"androgens":[103],"very":[105],"low":[106],"shows":[108],"no":[109],"sex":[110],"differences.":[111],"The":[112],"levels":[113],"plasma":[115],"prepubertal":[119],"boys":[120],"younger":[121],"than":[122],"years":[124],"around":[126],"0.05":[127],"ng/ml.":[128],"Puberty":[129],"begins":[130],"with":[131],"gradually":[132],"increasing":[133],"most":[139],"likely":[140],"due":[141],"changes":[143],"hypothalamic-pituitary":[146],"axis.":[147]},"counts_by_year":[{"year":2017,"cited_by_count":1},{"year":2015,"cited_by_count":1}],"updated_date":"2026-10-10T09:11:00.788812","created_date":"2020-08-03T00:00:00"}