{"id":"https://openalex.org/W3045897850","doi":"https://doi.org/10.1021/acsmaterialslett.0c00247","title":"Nanocarriers for Transgene Expression in Pollen as a Plant Biotechnology Tool","display_name":"Nanocarriers for Transgene Expression in Pollen as a Plant Biotechnology Tool","publication_year":2020,"publication_date":"2020-07-29","ids":{"openalex":"https://openalex.org/W3045897850","doi":"https://doi.org/10.1021/acsmaterialslett.0c00247","mag":"3045897850"},"language":"en","primary_location":{"id":"doi:10.1021/acsmaterialslett.0c00247","doi":"https://doi.org/10.1021/acsmaterialslett.0c00247","is_oa":false,"landing_page_url":"https://doi.org/10.1021/acsmaterialslett.0c00247","pdf_url":null,"source":{"id":"https://openalex.org/S4210213087","display_name":"ACS Materials Letters","issn_l":"2639-4979","issn":["2639-4979"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","jufo-1","ki-jl-1","norway-1","poland-20","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"ACS Materials Letters","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5090321920","display_name":"Tedrick Thomas Salim Lew","orcid":"https://orcid.org/0000-0002-4815-9921","observed_orcids":["https://orcid.org/0000-0002-4815-9921"]},"institutions":[{"id":"https://openalex.org/I63966007","display_name":"Massachusetts Institute of Technology","ror":"https://ror.org/042nb2s44","country_code":"US","type":"education","lineage":["https://openalex.org/I63966007"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Tedrick Thomas Salim Lew","raw_affiliation_strings":["Department of Chemical Engineering, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, Massachusetts 02139, United States"],"raw_orcid":"https://orcid.org/0000-0002-4815-9921","affiliations":[{"raw_affiliation_string":"Department of Chemical Engineering, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, Massachusetts 02139, United States","institution_ids":["https://openalex.org/I63966007"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101919045","display_name":"Minkyung Park","orcid":"https://orcid.org/0000-0002-6356-006X","observed_orcids":["https://orcid.org/0000-0002-6356-006X"]},"institutions":[{"id":"https://openalex.org/I63966007","display_name":"Massachusetts Institute of Technology","ror":"https://ror.org/042nb2s44","country_code":"US","type":"education","lineage":["https://openalex.org/I63966007"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Minkyung Park","raw_affiliation_strings":["Department of Chemical Engineering, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, Massachusetts 02139, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemical Engineering, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, Massachusetts 02139, United States","institution_ids":["https://openalex.org/I63966007"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083351215","display_name":"Yizhi Wang","orcid":"https://orcid.org/0000-0001-5279-5034","observed_orcids":["https://orcid.org/0000-0001-5279-5034"]},"institutions":[{"id":"https://openalex.org/I63966007","display_name":"Massachusetts Institute of Technology","ror":"https://ror.org/042nb2s44","country_code":"US","type":"education","lineage":["https://openalex.org/I63966007"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Yizhi Wang","raw_affiliation_strings":["Department of Chemical Engineering, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, Massachusetts 02139, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemical Engineering, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, Massachusetts 02139, United States","institution_ids":["https://openalex.org/I63966007"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039823903","display_name":"Pavlo I. Gordiichuk","orcid":"https://orcid.org/0000-0002-8275-1910","observed_orcids":["https://orcid.org/0000-0002-8275-1910"]},"institutions":[{"id":"https://openalex.org/I63966007","display_name":"Massachusetts Institute of Technology","ror":"https://ror.org/042nb2s44","country_code":"US","type":"education","lineage":["https://openalex.org/I63966007"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Pavlo Gordiichuk","raw_affiliation_strings":["Department of Chemical Engineering, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, Massachusetts 02139, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemical Engineering, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, Massachusetts 02139, United States","institution_ids":["https://openalex.org/I63966007"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056003080","display_name":"Wan\u2010Chin Yeap","orcid":"https://orcid.org/0000-0002-7982-9123","observed_orcids":["https://orcid.org/0000-0002-7982-9123"]},"institutions":[{"id":"https://openalex.org/I4405268543","display_name":"SD Guthrie Berhad (Malaysia)","ror":"https://ror.org/018wxwh49","country_code":"MY","type":"company","lineage":["https://openalex.org/I4405268543"]}],"countries":["MY"],"is_corresponding":false,"raw_author_name":"Wan-Chin Yeap","raw_affiliation_strings":["Sime Darby Plantation Technology Centre Sdn. Bhd., Serdang, Selangor Darul Ehsan 43400, Malaysia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Sime Darby Plantation Technology Centre Sdn. Bhd., Serdang, Selangor Darul Ehsan 43400, Malaysia","institution_ids":["https://openalex.org/I4405268543"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073604540","display_name":"Siti Khadijah Mohd Rais","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Siti Khadijah Mohd Rais","raw_affiliation_strings":["Sime Darby Plantation Research Sdn. Bhd., Banting, Selangor Darul Ehsan 42700 Malaysia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Sime Darby Plantation Research Sdn. Bhd., Banting, Selangor Darul Ehsan 42700 Malaysia","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038551548","display_name":"Harikrishna Kulaveerasingam","orcid":"https://orcid.org/0000-0001-8292-0457","observed_orcids":["https://orcid.org/0000-0001-8292-0457"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Harikrishna Kulaveerasingam","raw_affiliation_strings":["Sime Darby Plantation Research Sdn. Bhd., Banting, Selangor Darul Ehsan 42700 Malaysia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Sime Darby Plantation Research Sdn. Bhd., Banting, Selangor Darul Ehsan 42700 Malaysia","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5041330438","display_name":"Michael S. Strano","orcid":"https://orcid.org/0000-0003-2944-808X","observed_orcids":["https://orcid.org/0000-0003-2944-808X"]},"institutions":[{"id":"https://openalex.org/I63966007","display_name":"Massachusetts Institute of Technology","ror":"https://ror.org/042nb2s44","country_code":"US","type":"education","lineage":["https://openalex.org/I63966007"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Michael S. Strano","raw_affiliation_strings":["Department of Chemical Engineering, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, Massachusetts 02139, United States"],"raw_orcid":"https://orcid.org/0000-0003-2944-808X","affiliations":[{"raw_affiliation_string":"Department of Chemical Engineering, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, Massachusetts 02139, United States","institution_ids":["https://openalex.org/I63966007"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5041330438"],"corresponding_institution_ids":["https://openalex.org/I63966007"],"apc_list":{"value":5000,"currency":"USD","value_usd":5000},"apc_paid":null,"fwci":2.2869,"has_fulltext":false,"cited_by_count":58,"citation_normalized_percentile":{"value":0.89897732,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":93,"max":99},"biblio":{"volume":"2","issue":"9","first_page":"1057","last_page":"1066"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10725","display_name":"RNA Interference and Gene Delivery","score":0.8003000020980835,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10725","display_name":"RNA Interference and Gene Delivery","score":0.8003000020980835,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12642","display_name":"Polymer-Based Agricultural Enhancements","score":0.07620000094175339,"subfield":{"id":"https://openalex.org/subfields/1102","display_name":"Agronomy and Crop Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10704","display_name":"Advancements in Transdermal Drug Delivery","score":0.01269999984651804,"subfield":{"id":"https://openalex.org/subfields/3003","display_name":"Pharmaceutical Science"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/pollen","display_name":"pollen","score":0.5210000276565552},{"id":"https://openalex.org/keywords/nanocarriers","display_name":"nanocarriers","score":0.8690000176429749},{"id":"https://openalex.org/keywords/single-walled-carbon-nanotubes","display_name":"single-walled carbon nanotubes","score":0.953000009059906},{"id":"https://openalex.org/keywords/imidazolium-functionalization","display_name":"imidazolium functionalization","score":0.9670000076293945},{"id":"https://openalex.org/keywords/transgene-delivery","display_name":"transgene delivery","score":0.7329999804496765},{"id":"https://openalex.org/keywords/zeta-potential","display_name":"zeta potential","score":0.8899999856948853},{"id":"https://openalex.org/keywords/pollen-specific-promoter","display_name":"pollen-specific promoter","score":0.9190000295639038},{"id":"https://openalex.org/keywords/oil-palm","display_name":"oil palm","score":0.777999997138977},{"id":"https://openalex.org/keywords/biocompatibility","display_name":"biocompatibility","score":0.6690000295639038},{"id":"https://openalex.org/keywords/dielectric-constant","display_name":"dielectric constant","score":0.5559999942779541},{"id":"https://openalex.org/keywords/nanoparticle-transport","display_name":"nanoparticle transport","score":0.5540000200271606}],"concepts":[{"id":"https://openalex.org/C2780618852","wikidata":"https://www.wikidata.org/wiki/Q79932","display_name":"Pollen","level":2,"score":0.7872027158737183},{"id":"https://openalex.org/C18150654","wikidata":"https://www.wikidata.org/wiki/Q17153796","display_name":"Nanocarriers","level":3,"score":0.7637211680412292},{"id":"https://openalex.org/C148885314","wikidata":"https://www.wikidata.org/wiki/Q189951","display_name":"Gametophyte","level":3,"score":0.5999042987823486},{"id":"https://openalex.org/C102230213","wikidata":"https://www.wikidata.org/wiki/Q430117","display_name":"Transgene","level":3,"score":0.5275219082832336},{"id":"https://openalex.org/C2777230088","wikidata":"https://www.wikidata.org/wiki/Q864426","display_name":"Biocompatibility","level":2,"score":0.4965365529060364},{"id":"https://openalex.org/C122172344","wikidata":"https://www.wikidata.org/wiki/Q1503477","display_name":"Genetically modified crops","level":4,"score":0.46815040707588196},{"id":"https://openalex.org/C100701293","wikidata":"https://www.wikidata.org/wiki/Q193838","display_name":"Germination","level":2,"score":0.41059035062789917},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.40178775787353516},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.3986997604370117},{"id":"https://openalex.org/C150903083","wikidata":"https://www.wikidata.org/wiki/Q7108","display_name":"Biotechnology","level":1,"score":0.37291815876960754},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3505735993385315},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.3431087136268616},{"id":"https://openalex.org/C59822182","wikidata":"https://www.wikidata.org/wiki/Q441","display_name":"Botany","level":1,"score":0.33951979875564575},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.23941898345947266},{"id":"https://openalex.org/C155672457","wikidata":"https://www.wikidata.org/wiki/Q61231","display_name":"Nanoparticle","level":2,"score":0.22997653484344482},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.157274067401886},{"id":"https://openalex.org/C191897082","wikidata":"https://www.wikidata.org/wiki/Q11467","display_name":"Metallurgy","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1021/acsmaterialslett.0c00247","doi":"https://doi.org/10.1021/acsmaterialslett.0c00247","is_oa":false,"landing_page_url":"https://doi.org/10.1021/acsmaterialslett.0c00247","pdf_url":null,"source":{"id":"https://openalex.org/S4210213087","display_name":"ACS Materials Letters","issn_l":"2639-4979","issn":["2639-4979"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","jufo-1","ki-jl-1","norway-1","poland-20","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"ACS Materials Letters","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320320696","display_name":"Agency for Science, Technology and Research","ror":"https://ror.org/036wvzt09"},{"id":"https://openalex.org/F4320332195","display_name":"Samsung","ror":"https://ror.org/04w3jy968"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":57,"referenced_works":["https://openalex.org/W167008967","https://openalex.org/W1577071491","https://openalex.org/W1971213954","https://openalex.org/W1978978262","https://openalex.org/W1981619234","https://openalex.org/W1991925142","https://openalex.org/W2008565044","https://openalex.org/W2010343076","https://openalex.org/W2013841789","https://openalex.org/W2014880518","https://openalex.org/W2016960914","https://openalex.org/W2019761614","https://openalex.org/W2024630600","https://openalex.org/W2026122097","https://openalex.org/W2035131511","https://openalex.org/W2046736545","https://openalex.org/W2055808911","https://openalex.org/W2064720737","https://openalex.org/W2068522056","https://openalex.org/W2074064325","https://openalex.org/W2099320579","https://openalex.org/W2103021159","https://openalex.org/W2107794490","https://openalex.org/W2112387650","https://openalex.org/W2130509236","https://openalex.org/W2143495257","https://openalex.org/W2170135246","https://openalex.org/W2222676944","https://openalex.org/W2237004137","https://openalex.org/W2274584731","https://openalex.org/W2291777140","https://openalex.org/W2304549552","https://openalex.org/W2540081824","https://openalex.org/W2559992683","https://openalex.org/W2566198511","https://openalex.org/W2603312201","https://openalex.org/W2605474943","https://openalex.org/W2743092102","https://openalex.org/W2768919282","https://openalex.org/W2769424033","https://openalex.org/W2769583118","https://openalex.org/W2789318374","https://openalex.org/W2802556587","https://openalex.org/W2890419760","https://openalex.org/W2901026871","https://openalex.org/W2912064295","https://openalex.org/W2912904409","https://openalex.org/W2916239133","https://openalex.org/W2918418208","https://openalex.org/W2947519870","https://openalex.org/W2948794216","https://openalex.org/W2950849557","https://openalex.org/W2953161691","https://openalex.org/W2981510979","https://openalex.org/W2987769197","https://openalex.org/W2999341953","https://openalex.org/W3016412852"],"related_works":["https://openalex.org/W7134184562","https://openalex.org/W6990192964","https://openalex.org/W3088402251","https://openalex.org/W4411450166","https://openalex.org/W2973712516","https://openalex.org/W7149567147","https://openalex.org/W7157945252","https://openalex.org/W4319458194","https://openalex.org/W7164045452","https://openalex.org/W2916239133"],"abstract_inverted_index":{"As":[0],"the":[1,13,25,105,123,141,150,164],"male":[2],"gametophyte":[3],"of":[4,15,27,35,54,57,107,169],"flowering":[5],"plants,":[6],"pollen":[7,32,69,83,114,124,151],"grains":[8],"are":[9],"ideal":[10],"targets":[11],"for":[12,17,92,163,171],"introduction":[14],"transgenes":[16],"plant":[18,46,97,172],"genetic":[19],"engineering":[20],"and":[21,71,134,167],"crop":[22],"improvement.":[23],"However,":[24],"difficulty":[26],"delivering":[28],"exogenous":[29],"DNA":[30],"into":[31,95],"grains,":[33,84],"because":[34],"chemically":[36],"inert":[37],"cell":[38],"walls,":[39],"has":[40],"hindered":[41],"their":[42],"widespread":[43],"application":[44],"in":[45],"biotechnology.":[47],"Herein,":[48],"we":[49,103,135],"report":[50],"a":[51],"new":[52],"class":[53],"nanocarriers,":[55],"composed":[56],"imidazolium":[58],"(IM)-functionalized":[59],"single-walled":[60],"carbon":[61],"nanotubes":[62],"(SWNTs),":[63],"which":[64],"can":[65],"efficiently":[66],"traverse":[67],"past":[68,122],"barriers":[70],"deliver":[72],"genes":[73],"without":[74],"external":[75],"physical":[76],"aid.":[77],"IM-SWNTs":[78,100],"display":[79],"high":[80],"biocompatibility":[81],"with":[82,111,140,156],"compared":[85],"to":[86],"existing":[87],"SWNT":[88],"nanocarriers":[89,170],"previously":[90],"used":[91],"cargo":[93],"delivery":[94],"living":[96],"cells.":[98],"Using":[99],"as":[101],"nanotransporters,":[102],"investigate":[104],"compatibility":[106],"various":[108],"pollen-specific":[109],"promoters":[110],"oil":[112],"palm":[113],"transcription":[115],"machinery.":[116],"We":[117,147],"show":[118],"that":[119],"nanoparticle":[120],"transport":[121],"plasma":[125],"membrane":[126,152],"is":[127],"mainly":[128],"controlled":[129],"by":[130],"its":[131],"zeta":[132],"potential,":[133],"describe":[136],"this":[137,157],"entry":[138],"mechanism":[139],"lipid":[142],"exchange":[143],"envelope":[144],"penetration":[145],"model.":[146,158],"further":[148],"estimate":[149],"effective":[153],"dielectric":[154],"constant":[155],"These":[159],"findings":[160],"provide":[161],"insights":[162],"rational":[165],"design":[166],"refinement":[168],"biotechnology":[173],"applications.":[174]},"counts_by_year":[{"year":2026,"cited_by_count":8},{"year":2025,"cited_by_count":12},{"year":2024,"cited_by_count":6},{"year":2023,"cited_by_count":8},{"year":2022,"cited_by_count":13},{"year":2021,"cited_by_count":9},{"year":2020,"cited_by_count":2}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2020-08-03T00:00:00"}