{"id":"https://openalex.org/W3045859987","doi":"https://doi.org/10.3389/fendo.2020.00453","title":"Bisphenol A-Induced Epigenetic Changes and Its Effects on the Male Reproductive System","display_name":"Bisphenol A-Induced Epigenetic Changes and Its Effects on the Male Reproductive System","publication_year":2020,"publication_date":"2020-07-30","ids":{"openalex":"https://openalex.org/W3045859987","doi":"https://doi.org/10.3389/fendo.2020.00453","mag":"3045859987","pmid":"https://pubmed.ncbi.nlm.nih.gov/32849263","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/7406566"},"language":"en","primary_location":{"id":"doi:10.3389/fendo.2020.00453","doi":"https://doi.org/10.3389/fendo.2020.00453","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fendo.2020.00453","pdf_url":"https://www.frontiersin.org/articles/10.3389/fendo.2020.00453/pdf","source":{"id":"https://openalex.org/S2597401208","display_name":"Frontiers in Endocrinology","issn_l":"1664-2392","issn":["1664-2392"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","ki-jl-1","medline","norway-1","oarl","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Endocrinology","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.frontiersin.org/articles/10.3389/fendo.2020.00453/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5014558946","display_name":"Federica Cariati","orcid":"https://orcid.org/0009-0007-2495-860X","observed_orcids":["https://orcid.org/0009-0007-2495-860X","https://orcid.org/0000-0001-7116-4449"]},"institutions":[{"id":"https://openalex.org/I4210117450","display_name":"Federico II University Hospital","ror":"https://ror.org/02jr6tp70","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210117450","https://openalex.org/I71267560"]},{"id":"https://openalex.org/I4210128854","display_name":"CEINGE Biotecnologie Avanzate Franco Salvatore (Italy)","ror":"https://ror.org/033pa2k60","country_code":"IT","type":"company","lineage":["https://openalex.org/I4210128854"]}],"countries":["IT"],"is_corresponding":true,"raw_author_name":"Federica Cariati","raw_affiliation_strings":["CEINGE-Biotecnologie Avanzate s.c.a.r.l., Naples, Italy","Fertility Unit, Maternal-Child Department, AOU Policlinico Federico II, Naples, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"CEINGE-Biotecnologie Avanzate s.c.a.r.l., Naples, Italy","institution_ids":["https://openalex.org/I4210128854"]},{"raw_affiliation_string":"Fertility Unit, Maternal-Child Department, AOU Policlinico Federico II, Naples, Italy","institution_ids":["https://openalex.org/I4210117450"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032680865","display_name":"Luigi Carbone","orcid":"https://orcid.org/0000-0002-2127-1876","observed_orcids":["https://orcid.org/0000-0002-2127-1876"]},"institutions":[{"id":"https://openalex.org/I4210117450","display_name":"Federico II University Hospital","ror":"https://ror.org/02jr6tp70","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210117450","https://openalex.org/I71267560"]},{"id":"https://openalex.org/I71267560","display_name":"University of Naples Federico II","ror":"https://ror.org/05290cv24","country_code":"IT","type":"education","lineage":["https://openalex.org/I71267560"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Luigi Carbone","raw_affiliation_strings":["Department of Neuroscience, Reproductive Sciences and Odontostomatology, Federico II University, Naples, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neuroscience, Reproductive Sciences and Odontostomatology, Federico II University, Naples, Italy","institution_ids":["https://openalex.org/I4210117450","https://openalex.org/I71267560"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083714880","display_name":"Alessandro Conforti","orcid":"https://orcid.org/0000-0002-5676-0055","observed_orcids":["https://orcid.org/0000-0002-5676-0055"]},"institutions":[{"id":"https://openalex.org/I4210117450","display_name":"Federico II University Hospital","ror":"https://ror.org/02jr6tp70","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210117450","https://openalex.org/I71267560"]},{"id":"https://openalex.org/I71267560","display_name":"University of Naples Federico II","ror":"https://ror.org/05290cv24","country_code":"IT","type":"education","lineage":["https://openalex.org/I71267560"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Alessandro Conforti","raw_affiliation_strings":["Department of Neuroscience, Reproductive Sciences and Odontostomatology, Federico II University, Naples, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neuroscience, Reproductive Sciences and Odontostomatology, Federico II University, Naples, Italy","institution_ids":["https://openalex.org/I4210117450","https://openalex.org/I71267560"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023557335","display_name":"Francesca Bagnulo","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210117450","display_name":"Federico II University Hospital","ror":"https://ror.org/02jr6tp70","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210117450","https://openalex.org/I71267560"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Francesca Bagnulo","raw_affiliation_strings":["Fertility Unit, Maternal-Child Department, AOU Policlinico Federico II, Naples, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Fertility Unit, Maternal-Child Department, AOU Policlinico Federico II, Naples, Italy","institution_ids":["https://openalex.org/I4210117450"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020678947","display_name":"Stefania Ramona Peluso","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210117450","display_name":"Federico II University Hospital","ror":"https://ror.org/02jr6tp70","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210117450","https://openalex.org/I71267560"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Stefania Ramona Peluso","raw_affiliation_strings":["Fertility Unit, Maternal-Child Department, AOU Policlinico Federico II, Naples, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Fertility Unit, Maternal-Child Department, AOU Policlinico Federico II, Naples, Italy","institution_ids":["https://openalex.org/I4210117450"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056358975","display_name":"Consolata Carotenuto","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I71267560","display_name":"University of Naples Federico II","ror":"https://ror.org/05290cv24","country_code":"IT","type":"education","lineage":["https://openalex.org/I71267560"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Consolata Carotenuto","raw_affiliation_strings":["Molecular Medicine and Medical Biotechnology Department, Federico II University, Naples, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Molecular Medicine and Medical Biotechnology Department, Federico II University, Naples, Italy","institution_ids":["https://openalex.org/I71267560"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056494432","display_name":"Cira Buonfantino","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210117450","display_name":"Federico II University Hospital","ror":"https://ror.org/02jr6tp70","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210117450","https://openalex.org/I71267560"]},{"id":"https://openalex.org/I71267560","display_name":"University of Naples Federico II","ror":"https://ror.org/05290cv24","country_code":"IT","type":"education","lineage":["https://openalex.org/I71267560"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Cira Buonfantino","raw_affiliation_strings":["Department of Public Health, Federico II University, Naples, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Public Health, Federico II University, Naples, Italy","institution_ids":["https://openalex.org/I4210117450","https://openalex.org/I71267560"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058251871","display_name":"Erminia Alviggi","orcid":"https://orcid.org/0000-0003-3390-1211","observed_orcids":["https://orcid.org/0000-0003-3390-1211"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Erminia Alviggi","raw_affiliation_strings":["GENERA Centers for Reproductive Medicine, Clinica Ruesch, Naples, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"GENERA Centers for Reproductive Medicine, Clinica Ruesch, Naples, Italy","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077242442","display_name":"Carlo Alviggi","orcid":"https://orcid.org/0000-0001-9116-020X","observed_orcids":["https://orcid.org/0000-0001-9116-020X"]},"institutions":[{"id":"https://openalex.org/I4210117450","display_name":"Federico II University Hospital","ror":"https://ror.org/02jr6tp70","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210117450","https://openalex.org/I71267560"]},{"id":"https://openalex.org/I4210139435","display_name":"Institute for Experimental Endocrinology and Oncology","ror":"https://ror.org/04sn06036","country_code":"IT","type":"facility","lineage":["https://openalex.org/I4210139435","https://openalex.org/I4210155236"]},{"id":"https://openalex.org/I4210155236","display_name":"National Research Council","ror":"https://ror.org/04zaypm56","country_code":"IT","type":"nonprofit","lineage":["https://openalex.org/I4210155236"]},{"id":"https://openalex.org/I71267560","display_name":"University of Naples Federico II","ror":"https://ror.org/05290cv24","country_code":"IT","type":"education","lineage":["https://openalex.org/I71267560"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Carlo Alviggi","raw_affiliation_strings":["Department of Neuroscience, Reproductive Sciences and Odontostomatology, Federico II University, Naples, Italy","Endocrinology and Experimental Oncology Institute (IEOS), National Research Council, Naples, Italy","Fertility Unit, Maternal-Child Department, AOU Policlinico Federico II, Naples, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neuroscience, Reproductive Sciences and Odontostomatology, Federico II University, Naples, Italy","institution_ids":["https://openalex.org/I4210117450","https://openalex.org/I71267560"]},{"raw_affiliation_string":"Endocrinology and Experimental Oncology Institute (IEOS), National Research Council, Naples, Italy","institution_ids":["https://openalex.org/I4210139435","https://openalex.org/I4210155236"]},{"raw_affiliation_string":"Fertility Unit, Maternal-Child Department, AOU Policlinico Federico II, Naples, Italy","institution_ids":["https://openalex.org/I4210117450"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5009620943","display_name":"Ida Strina","orcid":"https://orcid.org/0000-0001-9484-6725","observed_orcids":["https://orcid.org/0000-0001-9484-6725"]},"institutions":[{"id":"https://openalex.org/I4210117450","display_name":"Federico II University Hospital","ror":"https://ror.org/02jr6tp70","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210117450","https://openalex.org/I71267560"]},{"id":"https://openalex.org/I71267560","display_name":"University of Naples Federico II","ror":"https://ror.org/05290cv24","country_code":"IT","type":"education","lineage":["https://openalex.org/I71267560"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Ida Strina","raw_affiliation_strings":["Department of Neuroscience, Reproductive Sciences and Odontostomatology, Federico II University, Naples, Italy","Fertility Unit, Maternal-Child Department, AOU Policlinico Federico II, Naples, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neuroscience, Reproductive Sciences and Odontostomatology, Federico II University, Naples, Italy","institution_ids":["https://openalex.org/I4210117450","https://openalex.org/I71267560"]},{"raw_affiliation_string":"Fertility Unit, Maternal-Child Department, AOU Policlinico Federico II, Naples, Italy","institution_ids":["https://openalex.org/I4210117450"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5014558946"],"corresponding_institution_ids":["https://openalex.org/I4210117450","https://openalex.org/I4210128854"],"apc_list":{"value":2950,"currency":"USD","value_usd":2950},"apc_paid":{"value":2950,"currency":"USD","value_usd":2950},"fwci":0.8508,"has_fulltext":true,"cited_by_count":84,"citation_normalized_percentile":{"value":0.66334842,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":98,"max":100},"biblio":{"volume":"11","issue":null,"first_page":"453","last_page":"453"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10686","display_name":"Effects and risks of endocrine disrupting chemicals","score":0.9452999830245972,"subfield":{"id":"https://openalex.org/subfields/2307","display_name":"Health, Toxicology and Mutagenesis"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10686","display_name":"Effects and risks of endocrine disrupting chemicals","score":0.9452999830245972,"subfield":{"id":"https://openalex.org/subfields/2307","display_name":"Health, Toxicology and Mutagenesis"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10269","display_name":"Epigenetics and DNA Methylation","score":0.05000000074505806,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10116","display_name":"Sperm and Testicular Function","score":0.0010000000474974513,"subfield":{"id":"https://openalex.org/subfields/2743","display_name":"Reproductive Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/bisphenol-a","display_name":"bisphenol A","score":0.9509999752044678},{"id":"https://openalex.org/keywords/epigenetic-modifications","display_name":"epigenetic modifications","score":0.7379999756813049},{"id":"https://openalex.org/keywords/male-reproductive-toxicity","display_name":"male reproductive toxicity","score":0.7490000128746033},{"id":"https://openalex.org/keywords/dna-methylation","display_name":"DNA methylation","score":0.9980000257492065},{"id":"https://openalex.org/keywords/endocrine-disruption","display_name":"endocrine disruption","score":0.8259999752044678},{"id":"https://openalex.org/keywords/male-reproductive-organs","display_name":"male reproductive organs","score":0.6150000095367432},{"id":"https://openalex.org/keywords/epigenetic-inheritance","display_name":"epigenetic inheritance","score":0.7139999866485596},{"id":"https://openalex.org/keywords/prostate-cancer","display_name":"prostate cancer","score":0.8090000152587891},{"id":"https://openalex.org/keywords/reproductive-hormones","display_name":"reproductive hormones","score":0.4189999997615814}],"concepts":[{"id":"https://openalex.org/C41091548","wikidata":"https://www.wikidata.org/wiki/Q26939","display_name":"Epigenetics","level":3,"score":0.9200439453125},{"id":"https://openalex.org/C190727270","wikidata":"https://www.wikidata.org/wiki/Q874745","display_name":"DNA methylation","level":4,"score":0.7769111394882202},{"id":"https://openalex.org/C2779684741","wikidata":"https://www.wikidata.org/wiki/Q271980","display_name":"Bisphenol A","level":3,"score":0.7302809953689575},{"id":"https://openalex.org/C539274931","wikidata":"https://www.wikidata.org/wiki/Q7895","display_name":"Reproductive system","level":2,"score":0.6442012786865234},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6115231513977051},{"id":"https://openalex.org/C2994310350","wikidata":"https://www.wikidata.org/wiki/Q842083","display_name":"Male reproductive system","level":3,"score":0.49340930581092834},{"id":"https://openalex.org/C2777693530","wikidata":"https://www.wikidata.org/wiki/Q6594689","display_name":"Benzhydryl compounds","level":4,"score":0.4762401878833771},{"id":"https://openalex.org/C33288867","wikidata":"https://www.wikidata.org/wiki/Q518328","display_name":"Methylation","level":3,"score":0.44021520018577576},{"id":"https://openalex.org/C59659247","wikidata":"https://www.wikidata.org/wiki/Q11990","display_name":"Reproduction","level":2,"score":0.43528348207473755},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.4266425669193268},{"id":"https://openalex.org/C71315377","wikidata":"https://www.wikidata.org/wiki/Q11364","display_name":"Hormone","level":2,"score":0.4238448143005371},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.35474520921707153},{"id":"https://openalex.org/C42407357","wikidata":"https://www.wikidata.org/wiki/Q521","display_name":"Physiology","level":1,"score":0.3382555842399597},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.31914520263671875},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.205175518989563},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.1915452480316162},{"id":"https://openalex.org/C2781087480","wikidata":"https://www.wikidata.org/wiki/Q17145","display_name":"Sperm","level":2,"score":0.16500496864318848},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0},{"id":"https://openalex.org/C166595027","wikidata":"https://www.wikidata.org/wiki/Q143983","display_name":"Epoxy","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000098826","descriptor_name":"Bisphenol A Compounds","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000395","descriptor_name":"Air Pollutants, Occupational","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D001559","descriptor_name":"Benzhydryl Compounds","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D005837","descriptor_name":"Genitalia, Male","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D005837","descriptor_name":"Genitalia, Male","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D005837","descriptor_name":"Genitalia, Male","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010636","descriptor_name":"Phenols","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D012098","descriptor_name":"Reproduction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D019175","descriptor_name":"DNA Methylation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D044127","descriptor_name":"Epigenesis, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D052244","descriptor_name":"Endocrine Disruptors","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.3389/fendo.2020.00453","doi":"https://doi.org/10.3389/fendo.2020.00453","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fendo.2020.00453","pdf_url":"https://www.frontiersin.org/articles/10.3389/fendo.2020.00453/pdf","source":{"id":"https://openalex.org/S2597401208","display_name":"Frontiers in Endocrinology","issn_l":"1664-2392","issn":["1664-2392"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","ki-jl-1","medline","norway-1","oarl","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Endocrinology","raw_type":"journal-article"},{"id":"pmid:32849263","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/32849263","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in endocrinology","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:7406566","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC7406566/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Front Endocrinol (Lausanne)","raw_type":"Text"},{"id":"pmh:oai:doaj.org/article:6e844432ec8d4bb49db43458c8e4d1a4","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/6e844432ec8d4bb49db43458c8e4d1a4","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Frontiers in Endocrinology, Vol 11 (2020)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.3389/fendo.2020.00453","doi":"https://doi.org/10.3389/fendo.2020.00453","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fendo.2020.00453","pdf_url":"https://www.frontiersin.org/articles/10.3389/fendo.2020.00453/pdf","source":{"id":"https://openalex.org/S2597401208","display_name":"Frontiers in Endocrinology","issn_l":"1664-2392","issn":["1664-2392"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","ki-jl-1","medline","norway-1","oarl","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Endocrinology","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.9391000270843506,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3045859987.pdf","grobid_xml":"https://content.openalex.org/works/W3045859987.grobid-xml"},"referenced_works_count":77,"referenced_works":["https://openalex.org/W1187536559","https://openalex.org/W1557205027","https://openalex.org/W1895000577","https://openalex.org/W1934738781","https://openalex.org/W1970760886","https://openalex.org/W1984977749","https://openalex.org/W1987437975","https://openalex.org/W1988448112","https://openalex.org/W1994048261","https://openalex.org/W1998650753","https://openalex.org/W1999414155","https://openalex.org/W2005984315","https://openalex.org/W2006866503","https://openalex.org/W2032653829","https://openalex.org/W2035662046","https://openalex.org/W2044104475","https://openalex.org/W2046318060","https://openalex.org/W2048052538","https://openalex.org/W2048637593","https://openalex.org/W2070584219","https://openalex.org/W2078327036","https://openalex.org/W2084092102","https://openalex.org/W2085178184","https://openalex.org/W2089794556","https://openalex.org/W2098813936","https://openalex.org/W2102242260","https://openalex.org/W2123606330","https://openalex.org/W2148619299","https://openalex.org/W2165329755","https://openalex.org/W2195999432","https://openalex.org/W2294566933","https://openalex.org/W2338170434","https://openalex.org/W2344332687","https://openalex.org/W2352734243","https://openalex.org/W2463376059","https://openalex.org/W2468164249","https://openalex.org/W2484467622","https://openalex.org/W2524587664","https://openalex.org/W2550185754","https://openalex.org/W2565658459","https://openalex.org/W2570167758","https://openalex.org/W2572235549","https://openalex.org/W2586502513","https://openalex.org/W2622724319","https://openalex.org/W2738481576","https://openalex.org/W2755762213","https://openalex.org/W2763314163","https://openalex.org/W2763927309","https://openalex.org/W2793524240","https://openalex.org/W2800782255","https://openalex.org/W2822543883","https://openalex.org/W2886816623","https://openalex.org/W2892372149","https://openalex.org/W2898256958","https://openalex.org/W2901058926","https://openalex.org/W2909316917","https://openalex.org/W2913331171","https://openalex.org/W2914450436","https://openalex.org/W2924162063","https://openalex.org/W2946934886","https://openalex.org/W2948332573","https://openalex.org/W2950671546","https://openalex.org/W2953517790","https://openalex.org/W2963179134","https://openalex.org/W2968042943","https://openalex.org/W2969029982","https://openalex.org/W2971016356","https://openalex.org/W2978438523","https://openalex.org/W2979057541","https://openalex.org/W2990271751","https://openalex.org/W2990597010","https://openalex.org/W2991480955","https://openalex.org/W2992389467","https://openalex.org/W2996686258","https://openalex.org/W2998612587","https://openalex.org/W3024895794","https://openalex.org/W3147476373"],"related_works":["https://openalex.org/W4400612573","https://openalex.org/W2763314163","https://openalex.org/W7138303855","https://openalex.org/W4391111935","https://openalex.org/W2513077713","https://openalex.org/W7215120172","https://openalex.org/W3033846465","https://openalex.org/W4206888910","https://openalex.org/W4308309648","https://openalex.org/W7132370378"],"abstract_inverted_index":{"Bisphenol":[0],"A":[1],"(BPA)":[2],"is":[3],"a":[4],"widespread":[5],"chemical":[6],"agent":[7],"which":[8],"can":[9],"exert":[10],"detrimental":[11],"effects":[12,64,105],"on":[13,106],"the":[14,41,57,96,107,115],"male":[15,73,108],"reproductive":[16,51,74,109],"system.":[17,110],"Exposure":[18],"to":[19,24,50,88,94,113],"BPA":[20,36,63,83,119],"has":[21],"been":[22],"shown":[23],"induce":[25],"several":[26],"epigenetic":[27,78,101],"modifications":[28],"in":[29],"both":[30],"animal":[31],"and":[32,69,76,103],"human":[33,81],"cells.":[34],"Specifically,":[35],"could":[37],"not":[38],"only":[39],"modify":[40],"methylation":[42],"pattern":[43],"of":[44,72,99,118],"multiple":[45],"genes":[46,58],"encoding":[47],"proteins":[48],"related":[49],"physiology":[52],"but":[53],"also":[54,86,121],"directly":[55],"influence":[56],"responsible":[59],"for":[60],"DNA":[61],"methylation.":[62],"include":[65],"hormonal":[66],"alterations,":[67],"microscopic":[68],"macroscopic":[70],"alteration":[71],"organs,":[75],"inheritable":[77],"changes":[79,102],"involving":[80],"reproduction.":[82],"exposure":[84],"was":[85],"linked":[87],"prostate":[89],"cancer.":[90],"This":[91],"review":[92],"aims":[93],"show":[95],"current":[97],"scenario":[98],"BPA-induced":[100],"its":[104],"Possible":[111],"strategies":[112],"counter":[114],"toxic":[116],"effect":[117],"were":[120],"addressed.":[122]},"counts_by_year":[{"year":2026,"cited_by_count":15},{"year":2025,"cited_by_count":13},{"year":2024,"cited_by_count":15},{"year":2023,"cited_by_count":7},{"year":2022,"cited_by_count":21},{"year":2021,"cited_by_count":13}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2020-08-03T00:00:00"}