{"id":"https://openalex.org/W3045668143","doi":"https://doi.org/10.4103/injr.injr_120_20","title":"Pathogenesis of Muscle Weakness in Inflammatory Myositis","display_name":"Pathogenesis of Muscle Weakness in Inflammatory Myositis","publication_year":2020,"publication_date":"2020-07-28","ids":{"openalex":"https://openalex.org/W3045668143","doi":"https://doi.org/10.4103/injr.injr_120_20","mag":"3045668143"},"language":"en","primary_location":{"id":"doi:10.4103/injr.injr_120_20","doi":"https://doi.org/10.4103/injr.injr_120_20","is_oa":true,"landing_page_url":"https://doi.org/10.4103/injr.injr_120_20","pdf_url":null,"source":{"id":"https://openalex.org/S5246876","display_name":"Indian Journal of Rheumatology","issn_l":"0973-3698","issn":["0973-3698","0973-3701"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1","poland-20","russia-white-list-4"],"host_organization":"https://openalex.org/P4310320448","host_organization_name":"Medknow","host_organization_lineage":["https://openalex.org/P4310320448","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Medknow","Wolters Kluwer"],"type":"journal"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Indian Journal of Rheumatology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://doi.org/10.4103/injr.injr_120_20","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5057967886","display_name":"Saikumar Dunga","orcid":"https://orcid.org/0000-0002-4440-6227","observed_orcids":["https://orcid.org/0000-0002-4440-6227"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Sai Kumar Dunga","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"T. G. Sundaram","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I161370692","display_name":"Sanjay Gandhi Post Graduate Institute of Medical Sciences","ror":"https://ror.org/01rsgrz10","country_code":"IN","type":"facility","lineage":["https://openalex.org/I161370692"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"T. G. Sundaram","raw_affiliation_strings":["Department of Clinical Immunology and Rheumatology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Clinical Immunology and Rheumatology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India","institution_ids":["https://openalex.org/I161370692"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5055037965","display_name":"Chengappa G. Kavadichanda","orcid":"https://orcid.org/0000-0002-3643-3989","observed_orcids":["https://orcid.org/0000-0002-3643-3989"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Chengappa G. Kavadichanda","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":0,"currency":"USD","value_usd":0},"apc_paid":null,"fwci":0.794,"has_fulltext":false,"cited_by_count":5,"citation_normalized_percentile":{"value":0.69390004,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"15","issue":"2S","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11724","display_name":"Inflammatory Myopathies and Dermatomyositis","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11724","display_name":"Inflammatory Myopathies and Dermatomyositis","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11576","display_name":"IgG4-Related and Inflammatory Diseases","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11271","display_name":"Myasthenia Gravis and Thymoma","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/idiopathic-inflammatory-myopathies","display_name":"idiopathic inflammatory myopathies","score":0.9620000123977661},{"id":"https://openalex.org/keywords/muscle-weakness","display_name":"muscle weakness","score":0.9470000267028809},{"id":"https://openalex.org/keywords/pathogenesis","display_name":"pathogenesis","score":0.8700000047683716},{"id":"https://openalex.org/keywords/autoimmune-disease","display_name":"autoimmune disease","score":0.6940000057220459},{"id":"https://openalex.org/keywords/fatigue","display_name":"fatigue","score":0.8029999732971191},{"id":"https://openalex.org/keywords/alveolitis","display_name":"alveolitis","score":0.8339999914169312},{"id":"https://openalex.org/keywords/immune-pathways","display_name":"immune pathways","score":0.7580000162124634},{"id":"https://openalex.org/keywords/histopathology","display_name":"histopathology","score":0.7749999761581421},{"id":"https://openalex.org/keywords/muscle-imaging","display_name":"muscle imaging","score":0.6520000100135803},{"id":"https://openalex.org/keywords/exercise-therapy","display_name":"exercise therapy","score":0.75}],"concepts":[{"id":"https://openalex.org/C2780247198","wikidata":"https://www.wikidata.org/wiki/Q633403","display_name":"Weakness","level":2,"score":0.8701021671295166},{"id":"https://openalex.org/C2776418732","wikidata":"https://www.wikidata.org/wiki/Q270421","display_name":"Muscle weakness","level":2,"score":0.8032894134521484},{"id":"https://openalex.org/C2781232998","wikidata":"https://www.wikidata.org/wiki/Q1433212","display_name":"Myositis","level":2,"score":0.8032569885253906},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7336091995239258},{"id":"https://openalex.org/C2909745897","wikidata":"https://www.wikidata.org/wiki/Q270421","display_name":"Proximal muscle weakness","level":4,"score":0.6453028321266174},{"id":"https://openalex.org/C2780942790","wikidata":"https://www.wikidata.org/wiki/Q372016","display_name":"Pathogenesis","level":2,"score":0.5261430740356445},{"id":"https://openalex.org/C10162356","wikidata":"https://www.wikidata.org/wiki/Q1135939","display_name":"Pathophysiology","level":2,"score":0.4774125814437866},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.3835723102092743},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.24317020177841187},{"id":"https://openalex.org/C2779999465","wikidata":"https://www.wikidata.org/wiki/Q2094702","display_name":"Muscle biopsy","level":3,"score":0.1529771387577057},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.13627934455871582},{"id":"https://openalex.org/C2775934546","wikidata":"https://www.wikidata.org/wiki/Q179991","display_name":"Biopsy","level":2,"score":0.09875097870826721}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.4103/injr.injr_120_20","doi":"https://doi.org/10.4103/injr.injr_120_20","is_oa":true,"landing_page_url":"https://doi.org/10.4103/injr.injr_120_20","pdf_url":null,"source":{"id":"https://openalex.org/S5246876","display_name":"Indian Journal of Rheumatology","issn_l":"0973-3698","issn":["0973-3698","0973-3701"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1","poland-20","russia-white-list-4"],"host_organization":"https://openalex.org/P4310320448","host_organization_name":"Medknow","host_organization_lineage":["https://openalex.org/P4310320448","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Medknow","Wolters Kluwer"],"type":"journal"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Indian Journal of Rheumatology","raw_type":"journal-article"},{"id":"pmh:oai:doaj.org/article:13ff849fd7f241a4a09d711b4fa1e595","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/13ff849fd7f241a4a09d711b4fa1e595","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Indian Journal of Rheumatology, Vol 15, Iss 6, Pp 99-111 (2020)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.4103/injr.injr_120_20","doi":"https://doi.org/10.4103/injr.injr_120_20","is_oa":true,"landing_page_url":"https://doi.org/10.4103/injr.injr_120_20","pdf_url":null,"source":{"id":"https://openalex.org/S5246876","display_name":"Indian Journal of Rheumatology","issn_l":"0973-3698","issn":["0973-3698","0973-3701"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1","poland-20","russia-white-list-4"],"host_organization":"https://openalex.org/P4310320448","host_organization_name":"Medknow","host_organization_lineage":["https://openalex.org/P4310320448","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Medknow","Wolters Kluwer"],"type":"journal"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Indian Journal of Rheumatology","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9537000060081482,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":99,"referenced_works":["https://openalex.org/W109924101","https://openalex.org/W1483945065","https://openalex.org/W1494573743","https://openalex.org/W1546401409","https://openalex.org/W1576137866","https://openalex.org/W1584807245","https://openalex.org/W1588081792","https://openalex.org/W1708748675","https://openalex.org/W1965650841","https://openalex.org/W1967687886","https://openalex.org/W1967884545","https://openalex.org/W1969737533","https://openalex.org/W1971418941","https://openalex.org/W1972725992","https://openalex.org/W1976373964","https://openalex.org/W1978718201","https://openalex.org/W1980047527","https://openalex.org/W1984551422","https://openalex.org/W1986288022","https://openalex.org/W1988375990","https://openalex.org/W1991445768","https://openalex.org/W1998867833","https://openalex.org/W2001290491","https://openalex.org/W2008711121","https://openalex.org/W2010870654","https://openalex.org/W2016490694","https://openalex.org/W2016945301","https://openalex.org/W2019842622","https://openalex.org/W2022020969","https://openalex.org/W2026506549","https://openalex.org/W2028797559","https://openalex.org/W2039035739","https://openalex.org/W2048174920","https://openalex.org/W2048468332","https://openalex.org/W2054163701","https://openalex.org/W2060149967","https://openalex.org/W2060227777","https://openalex.org/W2062378724","https://openalex.org/W2063601772","https://openalex.org/W2065181805","https://openalex.org/W2072215486","https://openalex.org/W2072335655","https://openalex.org/W2079293436","https://openalex.org/W2084802884","https://openalex.org/W2086342564","https://openalex.org/W2086758926","https://openalex.org/W2098043285","https://openalex.org/W2099375619","https://openalex.org/W2111008128","https://openalex.org/W2116886325","https://openalex.org/W2117249078","https://openalex.org/W2121267997","https://openalex.org/W2124756255","https://openalex.org/W2130106568","https://openalex.org/W2130384790","https://openalex.org/W2152578203","https://openalex.org/W2154007596","https://openalex.org/W2156507483","https://openalex.org/W2158020609","https://openalex.org/W2163758255","https://openalex.org/W2166485013","https://openalex.org/W2167019128","https://openalex.org/W2167950336","https://openalex.org/W2169477171","https://openalex.org/W2171418530","https://openalex.org/W2261272083","https://openalex.org/W2269941254","https://openalex.org/W2287985949","https://openalex.org/W2313206347","https://openalex.org/W2314050888","https://openalex.org/W2400303083","https://openalex.org/W2408113286","https://openalex.org/W2409562576","https://openalex.org/W2417138911","https://openalex.org/W2417496169","https://openalex.org/W2486570626","https://openalex.org/W2507871962","https://openalex.org/W2511344984","https://openalex.org/W2577072813","https://openalex.org/W2580901097","https://openalex.org/W2593921835","https://openalex.org/W2594432891","https://openalex.org/W2601406675","https://openalex.org/W2624234588","https://openalex.org/W2743069733","https://openalex.org/W2746703127","https://openalex.org/W2750136246","https://openalex.org/W2791310056","https://openalex.org/W2792190570","https://openalex.org/W2799525020","https://openalex.org/W2887863031","https://openalex.org/W2897063820","https://openalex.org/W2897356618","https://openalex.org/W2943815170","https://openalex.org/W2948017193","https://openalex.org/W2962911524","https://openalex.org/W2979676378","https://openalex.org/W2998836976","https://openalex.org/W4297900568"],"related_works":["https://openalex.org/W2154007596","https://openalex.org/W298160789","https://openalex.org/W7098273201","https://openalex.org/W1972456503","https://openalex.org/W2411168478","https://openalex.org/W2588175779","https://openalex.org/W2123205622","https://openalex.org/W2479865883","https://openalex.org/W2906429585","https://openalex.org/W2060149967"],"abstract_inverted_index":{"Idiopathic":[0],"inflammatory":[1],"myositis":[2],"(IIM)":[3],"is":[4,33,63],"a":[5,36],"heterogeneous":[6],"group":[7],"of":[8,38,57,60],"autoimmune":[9],"diseases.":[10],"These":[11],"are":[12],"characterized":[13],"by":[14],"muscle":[15,45,61,93],"weakness":[16,32,46,62,94],"and":[17,70,88,95,102],"fatigue":[18],"along":[19],"with":[20,40,76,98],"other":[21],"systemic":[22],"manifestations,":[23],"ranging":[24],"from":[25],"pulmonary":[26],"alveolitis":[27],"to":[28,65,84],"vasculopathic":[29],"ulcers.":[30],"Muscle":[31],"encountered":[34],"in":[35,74,92,105],"majority":[37],"individuals":[39],"IIM.":[41,77,106],"Several":[42],"hypotheses":[43],"for":[44],"have":[47,52,82],"been":[48,53],"proposed,":[49],"but":[50],"none":[51],"convincingly":[54],"proven.":[55],"Understanding":[56],"the":[58,86,99],"pathophysiology":[59],"necessary":[64],"better":[66],"delineate":[67,85],"therapeutic":[68],"options":[69],"tailor":[71],"exercise":[72],"regimens":[73],"patients":[75],"In":[78],"this":[79],"review,":[80],"we":[81],"attempted":[83],"immune":[87],"nonimmune":[89],"pathways":[90],"implicated":[91],"integrated":[96],"them":[97],"clinical,":[100],"histopathological,":[101],"imaging":[103],"findings":[104]},"counts_by_year":[{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":3}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2020-08-03T00:00:00"}