{"id":"https://openalex.org/W3045628124","doi":"https://doi.org/10.2147/cmar.s249348","title":"LncRNA MALAT1 Promotes the Proliferation, Migration, and Invasion of Melanoma Cells by Downregulating miR-23a","display_name":"LncRNA MALAT1 Promotes the Proliferation, Migration, and Invasion of Melanoma Cells by Downregulating miR-23a","publication_year":2020,"publication_date":"2020-07-01","ids":{"openalex":"https://openalex.org/W3045628124","doi":"https://doi.org/10.2147/cmar.s249348","mag":"3045628124","pmid":"https://pubmed.ncbi.nlm.nih.gov/32801893","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/7397564"},"language":"en","primary_location":{"id":"doi:10.2147/cmar.s249348","doi":"https://doi.org/10.2147/cmar.s249348","is_oa":true,"landing_page_url":"https://doi.org/10.2147/cmar.s249348","pdf_url":"https://www.dovepress.com/getfile.php?fileID=60132","source":{"id":"https://openalex.org/S2764554612","display_name":"Cancer Management and Research","issn_l":"1179-1322","issn":["1179-1322"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-c","jufo-1","ki-jl-1","norway-1","poland-140","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320348","host_organization_name":"Dove Medical Press","host_organization_lineage":["https://openalex.org/P4310320348","https://openalex.org/P4310320547"],"host_organization_lineage_names":["Dove Medical Press","Taylor & Francis"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer Management and Research","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.dovepress.com/getfile.php?fileID=60132","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100429787","display_name":"Pan Wang","orcid":"https://orcid.org/0000-0002-7235-2115","observed_orcids":["https://orcid.org/0000-0002-7235-2115"]},"institutions":[{"id":"https://openalex.org/I4210142622","display_name":"Wuhan Children's Hospital","ror":"https://ror.org/047c53f83","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210142622"]},{"id":"https://openalex.org/I47720641","display_name":"Huazhong University of Science and Technology","ror":"https://ror.org/00p991c53","country_code":"CN","type":"education","lineage":["https://openalex.org/I47720641"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Pan Wang","raw_affiliation_strings":["Department of Dermatology, Wuhan Children's Hospital (Wuhan Maternal and Child Healthcare Hospital), Tongji Medical College, Huazhong University of Science & Technology, Wuhan 430015, Hubei Province, People's Republic of China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Dermatology, Wuhan Children's Hospital (Wuhan Maternal and Child Healthcare Hospital), Tongji Medical College, Huazhong University of Science & Technology, Wuhan 430015, Hubei Province, People's Republic of China","institution_ids":["https://openalex.org/I4210142622","https://openalex.org/I47720641"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100382887","display_name":"Hu Liu","orcid":"https://orcid.org/0000-0001-6774-6868","observed_orcids":["https://orcid.org/0000-0001-6774-6868"]},"institutions":[{"id":"https://openalex.org/I4210160841","display_name":"Hubei Cancer Hospital","ror":"https://ror.org/05p38yh32","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210160841"]},{"id":"https://openalex.org/I47720641","display_name":"Huazhong University of Science and Technology","ror":"https://ror.org/00p991c53","country_code":"CN","type":"education","lineage":["https://openalex.org/I47720641"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Liu Hu","raw_affiliation_strings":["Department of Radiotherapy, Hubei Cancer Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei Province, 430071, People's Republic of China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiotherapy, Hubei Cancer Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei Province, 430071, People's Republic of China","institution_ids":["https://openalex.org/I4210160841","https://openalex.org/I47720641"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047209924","display_name":"Guili Fu","orcid":"https://orcid.org/0000-0003-4659-7466","observed_orcids":["https://orcid.org/0000-0003-4659-7466"]},"institutions":[{"id":"https://openalex.org/I4210142622","display_name":"Wuhan Children's Hospital","ror":"https://ror.org/047c53f83","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210142622"]},{"id":"https://openalex.org/I47720641","display_name":"Huazhong University of Science and Technology","ror":"https://ror.org/00p991c53","country_code":"CN","type":"education","lineage":["https://openalex.org/I47720641"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Guili Fu","raw_affiliation_strings":["Department of Dermatology, Wuhan Children's Hospital (Wuhan Maternal and Child Healthcare Hospital), Tongji Medical College, Huazhong University of Science & Technology, Wuhan 430015, Hubei Province, People's Republic of China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Dermatology, Wuhan Children's Hospital (Wuhan Maternal and Child Healthcare Hospital), Tongji Medical College, Huazhong University of Science & Technology, Wuhan 430015, Hubei Province, People's Republic of China","institution_ids":["https://openalex.org/I4210142622","https://openalex.org/I47720641"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013693577","display_name":"Jingjing Lu","orcid":"https://orcid.org/0000-0003-2841-3117","observed_orcids":["https://orcid.org/0000-0003-2841-3117"]},"institutions":[{"id":"https://openalex.org/I4210142622","display_name":"Wuhan Children's Hospital","ror":"https://ror.org/047c53f83","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210142622"]},{"id":"https://openalex.org/I47720641","display_name":"Huazhong University of Science and Technology","ror":"https://ror.org/00p991c53","country_code":"CN","type":"education","lineage":["https://openalex.org/I47720641"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jingjing Lu","raw_affiliation_strings":["Department of Dermatology, Wuhan Children's Hospital (Wuhan Maternal and Child Healthcare Hospital), Tongji Medical College, Huazhong University of Science & Technology, Wuhan 430015, Hubei Province, People's Republic of China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Dermatology, Wuhan Children's Hospital (Wuhan Maternal and Child Healthcare Hospital), Tongji Medical College, Huazhong University of Science & Technology, Wuhan 430015, Hubei Province, People's Republic of China","institution_ids":["https://openalex.org/I4210142622","https://openalex.org/I47720641"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5015293023","display_name":"Yuanquan Zheng","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210142622","display_name":"Wuhan Children's Hospital","ror":"https://ror.org/047c53f83","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210142622"]},{"id":"https://openalex.org/I47720641","display_name":"Huazhong University of Science and Technology","ror":"https://ror.org/00p991c53","country_code":"CN","type":"education","lineage":["https://openalex.org/I47720641"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yuanquan Zheng","raw_affiliation_strings":["Department of Dermatology, Wuhan Children's Hospital (Wuhan Maternal and Child Healthcare Hospital), Tongji Medical College, Huazhong University of Science & Technology, Wuhan 430015, Hubei Province, People's Republic of China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Dermatology, Wuhan Children's Hospital (Wuhan Maternal and Child Healthcare Hospital), Tongji Medical College, Huazhong University of Science & Technology, Wuhan 430015, Hubei Province, People's Republic of China","institution_ids":["https://openalex.org/I4210142622","https://openalex.org/I47720641"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100414228","display_name":"Ying Li","orcid":"https://orcid.org/0000-0002-4286-876X","observed_orcids":["https://orcid.org/0000-0002-4286-876X"]},"institutions":[{"id":"https://openalex.org/I4210160841","display_name":"Hubei Cancer Hospital","ror":"https://ror.org/05p38yh32","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210160841"]},{"id":"https://openalex.org/I47720641","display_name":"Huazhong University of Science and Technology","ror":"https://ror.org/00p991c53","country_code":"CN","type":"education","lineage":["https://openalex.org/I47720641"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Ying Li","raw_affiliation_strings":["Department of Radiotherapy, Hubei Cancer Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei Province, 430071, People's Republic of China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiotherapy, Hubei Cancer Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei Province, 430071, People's Republic of China","institution_ids":["https://openalex.org/I4210160841","https://openalex.org/I47720641"]}]},{"author_position":"last","author":{"id":null,"display_name":"Lin Jia","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210143568","display_name":"Central Hospital of Wuhan","ror":"https://ror.org/04qs2sz84","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210143568"]},{"id":"https://openalex.org/I47720641","display_name":"Huazhong University of Science and Technology","ror":"https://ror.org/00p991c53","country_code":"CN","type":"education","lineage":["https://openalex.org/I47720641"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Lin Jia","raw_affiliation_strings":["Department of Nephrology, The Central Hosptial of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430015, Hubei Province, People's Republic of China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Nephrology, The Central Hosptial of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430015, Hubei Province, People's Republic of China","institution_ids":["https://openalex.org/I4210143568","https://openalex.org/I47720641"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5100414228"],"corresponding_institution_ids":["https://openalex.org/I4210160841","https://openalex.org/I47720641"],"apc_list":{"value":2836,"currency":"USD","value_usd":2836},"apc_paid":{"value":2836,"currency":"USD","value_usd":2836},"fwci":1.5035,"has_fulltext":true,"cited_by_count":31,"citation_normalized_percentile":{"value":0.81943583,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"Volume 12","issue":null,"first_page":"6553","last_page":"6562"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10515","display_name":"Cancer-related molecular mechanisms research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10515","display_name":"Cancer-related molecular mechanisms research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10062","display_name":"MicroRNA in disease regulation","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11482","display_name":"RNA modifications and cancer","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/malat1","display_name":"MALAT1","score":0.9810000061988831},{"id":"https://openalex.org/keywords/mir-23a","display_name":"miR-23a","score":0.9950000047683716},{"id":"https://openalex.org/keywords/melanoma","display_name":"melanoma","score":0.9919999837875366},{"id":"https://openalex.org/keywords/metastatic-melanoma","display_name":"metastatic melanoma","score":0.9649999737739563},{"id":"https://openalex.org/keywords/cell-proliferation","display_name":"cell proliferation","score":0.6990000009536743},{"id":"https://openalex.org/keywords/cell-migration","display_name":"cell migration","score":0.9729999899864197},{"id":"https://openalex.org/keywords/cell-invasion","display_name":"cell invasion","score":0.9070000052452087},{"id":"https://openalex.org/keywords/apoptosis","display_name":"apoptosis","score":0.9819999933242798},{"id":"https://openalex.org/keywords/lncrna-mirna-interaction","display_name":"lncRNA-miRNA interaction","score":0.8259999752044678},{"id":"https://openalex.org/keywords/microrna-downregulation","display_name":"microRNA downregulation","score":0.5709999799728394}],"concepts":[{"id":"https://openalex.org/C2779134362","wikidata":"https://www.wikidata.org/wiki/Q18056223","display_name":"MALAT1","level":5,"score":0.7667416334152222},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.6526049375534058},{"id":"https://openalex.org/C2777658100","wikidata":"https://www.wikidata.org/wiki/Q180614","display_name":"Melanoma","level":2,"score":0.4551749527454376},{"id":"https://openalex.org/C62112901","wikidata":"https://www.wikidata.org/wiki/Q189159","display_name":"Cell growth","level":2,"score":0.4104597270488739},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.394776850938797},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3636930286884308},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3285433053970337},{"id":"https://openalex.org/C127561419","wikidata":"https://www.wikidata.org/wiki/Q224527","display_name":"Downregulation and upregulation","level":3,"score":0.1866554617881775},{"id":"https://openalex.org/C62203573","wikidata":"https://www.wikidata.org/wiki/Q15087973","display_name":"Long non-coding RNA","level":4,"score":0.17240563035011292},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.10263863205909729},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.03939443826675415}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.2147/cmar.s249348","doi":"https://doi.org/10.2147/cmar.s249348","is_oa":true,"landing_page_url":"https://doi.org/10.2147/cmar.s249348","pdf_url":"https://www.dovepress.com/getfile.php?fileID=60132","source":{"id":"https://openalex.org/S2764554612","display_name":"Cancer Management and Research","issn_l":"1179-1322","issn":["1179-1322"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-c","jufo-1","ki-jl-1","norway-1","poland-140","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320348","host_organization_name":"Dove Medical Press","host_organization_lineage":["https://openalex.org/P4310320348","https://openalex.org/P4310320547"],"host_organization_lineage_names":["Dove Medical Press","Taylor & Francis"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer Management and Research","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:7397564","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/7397564","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer Manag Res","raw_type":"Text"},{"id":"pmid:32801893","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/32801893","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer management and research","raw_type":"Journal Article"},{"id":"pmh:oai:dovepress.com/55761","doi":null,"is_oa":true,"landing_page_url":"https://www.dovepress.com/lncrna-malat1-promotes-the-proliferation-migration-and-invasion-of-mel-peer-reviewed-article-CMAR","pdf_url":null,"source":{"id":"https://openalex.org/S4306401012","display_name":"Dove Medical Press (Taylor and Francis Group)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.2147/cmar.s249348","doi":"https://doi.org/10.2147/cmar.s249348","is_oa":true,"landing_page_url":"https://doi.org/10.2147/cmar.s249348","pdf_url":"https://www.dovepress.com/getfile.php?fileID=60132","source":{"id":"https://openalex.org/S2764554612","display_name":"Cancer Management and Research","issn_l":"1179-1322","issn":["1179-1322"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-c","jufo-1","ki-jl-1","norway-1","poland-140","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320348","host_organization_name":"Dove Medical Press","host_organization_lineage":["https://openalex.org/P4310320348","https://openalex.org/P4310320547"],"host_organization_lineage_names":["Dove Medical Press","Taylor & Francis"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer Management and Research","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.98580002784729}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3045628124.pdf","grobid_xml":"https://content.openalex.org/works/W3045628124.grobid-xml"},"referenced_works_count":30,"referenced_works":["https://openalex.org/W2227182487","https://openalex.org/W2330589406","https://openalex.org/W2410788706","https://openalex.org/W2414387768","https://openalex.org/W2484922909","https://openalex.org/W2486287298","https://openalex.org/W2520814675","https://openalex.org/W2560101115","https://openalex.org/W2750530161","https://openalex.org/W2755103617","https://openalex.org/W2889982462","https://openalex.org/W2892712216","https://openalex.org/W2897827148","https://openalex.org/W2898356531","https://openalex.org/W2906362794","https://openalex.org/W2914992819","https://openalex.org/W2920907165","https://openalex.org/W2921713582","https://openalex.org/W2923560210","https://openalex.org/W2924598449","https://openalex.org/W2941724686","https://openalex.org/W2945922564","https://openalex.org/W2962996429","https://openalex.org/W2969680608","https://openalex.org/W2982373493","https://openalex.org/W2982404887","https://openalex.org/W2983138989","https://openalex.org/W2989947580","https://openalex.org/W2990790855","https://openalex.org/W2991478352"],"related_works":["https://openalex.org/W2047330407","https://openalex.org/W2906995803","https://openalex.org/W2510516621","https://openalex.org/W2606878667","https://openalex.org/W2760283151","https://openalex.org/W4205413657","https://openalex.org/W4381050735","https://openalex.org/W2995546924","https://openalex.org/W2892745211","https://openalex.org/W2969680608"],"abstract_inverted_index":{"PURPOSE:":[0],"This":[1],"study":[2],"was":[3,129,133],"designed":[4],"to":[5,76,101,148],"investigate":[6],"the":[7,59,72,77],"relationship":[8],"between":[9],"long-chain":[10],"non-coding":[11],"RNA":[12],"metastasis-associated":[13],"lung":[14],"adenocarcinoma":[15],"transcript":[16],"1":[17],"(lncRNA":[18],"MALAT1)/miR-23a-23a":[19],"and":[20,32,41,55,57,65,83,88,94,131,143,160,162],"melanoma.":[21],"PATIENTS":[22],"AND":[23],"METHODS:":[24],"Fifty-two":[25],"cases":[26,34,37,43],"of":[27,38,44,62,80,136,141,170,179,188],"corresponding":[28,110],"non-tumor":[29,111],"normal":[30,112],"tissues":[31],"109":[33],"(including":[35],"62":[36],"primary":[39,125],"melanoma":[40,97,117,128,189],"47":[42],"metastatic":[45,127],"melanoma)":[46],"were":[47,92],"collected.":[48],"Real-time":[49],"fluorescent":[50],"PCR":[51],"quantified":[52],"lncRNA":[53,67,81,85,114,137,144,151,180,183],"MALAT1":[54,68,82,86,115,138,145,152,184],"miR-23a,":[56,142],"counted":[58],"3-year":[60],"survival":[61],"high/low":[63,66],"miR-23":[64],"populations.":[69],"We":[70],"predicted":[71],"binding":[73],"site":[74],"according":[75],"sequence":[78],"information":[79],"miR-23a.":[84,149,192],"siRNA":[87],"miR-23a":[89,121,132,155,171],"mimics":[90],"vectors":[91],"constructed":[93],"transfected":[95],"into":[96],"cell":[98,157,174],"lines":[99],"respectively":[100],"observe":[102],"their":[103],"effects":[104],"on":[105],"cells.":[106],"RESULTS:":[107],"Compared":[108,123],"with":[109,124],"tissues,":[113],"in":[116],"tissue":[118],"increased":[119],"while":[120],"decreased.":[122],"melanoma,":[126],"higher":[130],"lower.":[134],"Downregulation":[135],"caused":[139,176],"upregulation":[140],"could":[146,172],"bind":[147],"Downregulating":[150],"or":[153],"upregulating":[154],"inhibited":[156],"proliferation,":[158],"migration":[159],"invasion":[161],"promoted":[163],"apoptosis.":[164],"Rescue":[165],"experiments":[166],"revealed":[167],"that":[168],"downregulation":[169,178],"offset":[173],"changes":[175],"by":[177],"MALAT1.":[181],"CONCLUSION:":[182],"promotes":[185],"malignant":[186],"proliferation":[187],"cells":[190],"through":[191]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":4},{"year":2024,"cited_by_count":7},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":7},{"year":2021,"cited_by_count":9},{"year":2020,"cited_by_count":1}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2020-08-03T00:00:00"}