{"id":"https://openalex.org/W3045500558","doi":"https://doi.org/10.3390/life10080127","title":"Prevalence and Clinical Characteristics of Children and Adolescents with Metabolically Healthy Obesity: Role of Insulin Sensitivity","display_name":"Prevalence and Clinical Characteristics of Children and Adolescents with Metabolically Healthy Obesity: Role of Insulin Sensitivity","publication_year":2020,"publication_date":"2020-07-28","ids":{"openalex":"https://openalex.org/W3045500558","doi":"https://doi.org/10.3390/life10080127","mag":"3045500558","pmid":"https://pubmed.ncbi.nlm.nih.gov/32731619","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/7459932"},"language":"en","primary_location":{"id":"doi:10.3390/life10080127","doi":"https://doi.org/10.3390/life10080127","is_oa":true,"landing_page_url":"https://doi.org/10.3390/life10080127","pdf_url":"https://www.mdpi.com/2075-1729/10/8/127/pdf?version=1596011257","source":{"id":"https://openalex.org/S4210200765","display_name":"Life","issn_l":"2075-1729","issn":["2075-1729"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Life","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.mdpi.com/2075-1729/10/8/127/pdf?version=1596011257","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5087616500","display_name":"Federica Vinciguerra","orcid":"https://orcid.org/0000-0001-9916-4272","observed_orcids":["https://orcid.org/0000-0001-9916-4272"]},"institutions":[{"id":"https://openalex.org/I39063666","display_name":"University of Catania","ror":"https://ror.org/03a64bh57","country_code":"IT","type":"education","lineage":["https://openalex.org/I39063666"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Federica Vinciguerra","raw_affiliation_strings":["Endocrinology, Department of Clinical and Experimental Medicine, University of Catania, 95122 Catania, Italy"],"raw_orcid":"https://orcid.org/0000-0001-9916-4272","affiliations":[{"raw_affiliation_string":"Endocrinology, Department of Clinical and Experimental Medicine, University of Catania, 95122 Catania, Italy","institution_ids":["https://openalex.org/I39063666"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023679095","display_name":"Andrea Tumminia","orcid":"https://orcid.org/0000-0001-5820-4178","observed_orcids":["https://orcid.org/0000-0001-5820-4178"]},"institutions":[{"id":"https://openalex.org/I39063666","display_name":"University of Catania","ror":"https://ror.org/03a64bh57","country_code":"IT","type":"education","lineage":["https://openalex.org/I39063666"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Andrea Tumminia","raw_affiliation_strings":["Endocrinology, Department of Clinical and Experimental Medicine, University of Catania, 95122 Catania, Italy"],"raw_orcid":"https://orcid.org/0000-0001-5820-4178","affiliations":[{"raw_affiliation_string":"Endocrinology, Department of Clinical and Experimental Medicine, University of Catania, 95122 Catania, Italy","institution_ids":["https://openalex.org/I39063666"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002294906","display_name":"Roberto Baratta","orcid":"https://orcid.org/0000-0003-0524-4525","observed_orcids":["https://orcid.org/0000-0003-0524-4525"]},"institutions":[{"id":"https://openalex.org/I4210105999","display_name":"Ospedale Garibaldi","ror":"https://ror.org/01q6hrg49","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210105999"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Roberto Baratta","raw_affiliation_strings":["Diabetes, Obesity and Dietetic Center, Garibaldi-Nesima Medical Center, 95122 Catania, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Diabetes, Obesity and Dietetic Center, Garibaldi-Nesima Medical Center, 95122 Catania, Italy","institution_ids":["https://openalex.org/I4210105999"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000272110","display_name":"Alfredo Ferro","orcid":"https://orcid.org/0000-0002-9431-5788","observed_orcids":["https://orcid.org/0000-0002-9431-5788"]},"institutions":[{"id":"https://openalex.org/I39063666","display_name":"University of Catania","ror":"https://ror.org/03a64bh57","country_code":"IT","type":"education","lineage":["https://openalex.org/I39063666"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Alfredo Ferro","raw_affiliation_strings":["Bionformatic Unit, Department of Clinical and Experimental Medicine, University of Catania, 95125 Catania, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bionformatic Unit, Department of Clinical and Experimental Medicine, University of Catania, 95125 Catania, Italy","institution_ids":["https://openalex.org/I39063666"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023263135","display_name":"Salvatore Alaimo","orcid":"https://orcid.org/0000-0003-4825-7617","observed_orcids":["https://orcid.org/0000-0003-4825-7617"]},"institutions":[{"id":"https://openalex.org/I39063666","display_name":"University of Catania","ror":"https://ror.org/03a64bh57","country_code":"IT","type":"education","lineage":["https://openalex.org/I39063666"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Salvatore Alaimo","raw_affiliation_strings":["Bionformatic Unit, Department of Clinical and Experimental Medicine, University of Catania, 95125 Catania, Italy"],"raw_orcid":"https://orcid.org/0000-0003-4825-7617","affiliations":[{"raw_affiliation_string":"Bionformatic Unit, Department of Clinical and Experimental Medicine, University of Catania, 95125 Catania, Italy","institution_ids":["https://openalex.org/I39063666"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089549494","display_name":"Maria P. Hagn\u00e4s","orcid":"https://orcid.org/0000-0002-8825-0551","observed_orcids":["https://orcid.org/0000-0002-8825-0551"]},"institutions":[{"id":"https://openalex.org/I39063666","display_name":"University of Catania","ror":"https://ror.org/03a64bh57","country_code":"IT","type":"education","lineage":["https://openalex.org/I39063666"]},{"id":"https://openalex.org/I98381234","display_name":"University of Oulu","ror":"https://ror.org/03yj89h83","country_code":"FI","type":"education","lineage":["https://openalex.org/I98381234"]}],"countries":["FI","IT"],"is_corresponding":false,"raw_author_name":"Maria Hagn\u00e4s","raw_affiliation_strings":["Center for Life Course Health Research, University of Oulu, 90570 Oulu, Finland","Endocrinology, Department of Clinical and Experimental Medicine, University of Catania, 95122 Catania, Italy","Rovaniemi Health Center, 96200 Rovaniemi, Finland"],"raw_orcid":"https://orcid.org/0000-0002-8825-0551","affiliations":[{"raw_affiliation_string":"Center for Life Course Health Research, University of Oulu, 90570 Oulu, Finland","institution_ids":["https://openalex.org/I98381234"]},{"raw_affiliation_string":"Endocrinology, Department of Clinical and Experimental Medicine, University of Catania, 95122 Catania, Italy","institution_ids":["https://openalex.org/I39063666"]},{"raw_affiliation_string":"Rovaniemi Health Center, 96200 Rovaniemi, Finland","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052381311","display_name":"Marco Graziano","orcid":"https://orcid.org/0000-0002-2289-6704","observed_orcids":["https://orcid.org/0000-0002-2289-6704"]},"institutions":[{"id":"https://openalex.org/I39063666","display_name":"University of Catania","ror":"https://ror.org/03a64bh57","country_code":"IT","type":"education","lineage":["https://openalex.org/I39063666"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Marco Graziano","raw_affiliation_strings":["Endocrinology, Department of Clinical and Experimental Medicine, University of Catania, 95122 Catania, Italy"],"raw_orcid":"https://orcid.org/0000-0002-2289-6704","affiliations":[{"raw_affiliation_string":"Endocrinology, Department of Clinical and Experimental Medicine, University of Catania, 95122 Catania, Italy","institution_ids":["https://openalex.org/I39063666"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019197295","display_name":"Riccardo Vigneri","orcid":"https://orcid.org/0000-0002-4401-3140","observed_orcids":["https://orcid.org/0000-0002-4401-3140"]},"institutions":[{"id":"https://openalex.org/I39063666","display_name":"University of Catania","ror":"https://ror.org/03a64bh57","country_code":"IT","type":"education","lineage":["https://openalex.org/I39063666"]},{"id":"https://openalex.org/I4210155236","display_name":"National Research Council","ror":"https://ror.org/04zaypm56","country_code":"IT","type":"nonprofit","lineage":["https://openalex.org/I4210155236"]},{"id":"https://openalex.org/I4210166808","display_name":"Institute of Crystallography","ror":"https://ror.org/05wba8r86","country_code":"IT","type":"facility","lineage":["https://openalex.org/I4210155236","https://openalex.org/I4210166808"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Riccardo Vigneri","raw_affiliation_strings":["Endocrinology, Department of Clinical and Experimental Medicine, University of Catania, 95122 Catania, Italy","Institute of Crystallography, Structural Chemistry and Biosystems, CNR-ICCSB, Catania Section, 95126 Catania, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Endocrinology, Department of Clinical and Experimental Medicine, University of Catania, 95122 Catania, Italy","institution_ids":["https://openalex.org/I39063666"]},{"raw_affiliation_string":"Institute of Crystallography, Structural Chemistry and Biosystems, CNR-ICCSB, Catania Section, 95126 Catania, Italy","institution_ids":["https://openalex.org/I4210155236","https://openalex.org/I4210166808"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5078176024","display_name":"Lucia Frittitta","orcid":"https://orcid.org/0000-0002-7941-5828","observed_orcids":["https://orcid.org/0000-0002-7941-5828"]},"institutions":[{"id":"https://openalex.org/I39063666","display_name":"University of Catania","ror":"https://ror.org/03a64bh57","country_code":"IT","type":"education","lineage":["https://openalex.org/I39063666"]},{"id":"https://openalex.org/I4210105999","display_name":"Ospedale Garibaldi","ror":"https://ror.org/01q6hrg49","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210105999"]}],"countries":["IT"],"is_corresponding":true,"raw_author_name":"Lucia Frittitta","raw_affiliation_strings":["Diabetes, Obesity and Dietetic Center, Garibaldi-Nesima Medical Center, 95122 Catania, Italy","Endocrinology, Department of Clinical and Experimental Medicine, University of Catania, 95122 Catania, Italy"],"raw_orcid":"https://orcid.org/0000-0002-7941-5828","affiliations":[{"raw_affiliation_string":"Diabetes, Obesity and Dietetic Center, Garibaldi-Nesima Medical Center, 95122 Catania, Italy","institution_ids":["https://openalex.org/I4210105999"]},{"raw_affiliation_string":"Endocrinology, Department of Clinical and Experimental Medicine, University of Catania, 95122 Catania, Italy","institution_ids":["https://openalex.org/I39063666"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5078176024"],"corresponding_institution_ids":["https://openalex.org/I39063666","https://openalex.org/I4210105999"],"apc_list":{"value":1400,"currency":"CHF","value_usd":1479},"apc_paid":{"value":1400,"currency":"CHF","value_usd":1479},"fwci":1.4819,"has_fulltext":true,"cited_by_count":20,"citation_normalized_percentile":{"value":0.81304748,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"10","issue":"8","first_page":"127","last_page":"127"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10027","display_name":"Diabetes, Cardiovascular Risks, and Lipoproteins","score":0.9086999893188477,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10027","display_name":"Diabetes, Cardiovascular Risks, and Lipoproteins","score":0.9086999893188477,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10010","display_name":"Obesity, Physical Activity, Diet","score":0.06469999998807907,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10528","display_name":"Adipokines, Inflammation, and Metabolic Diseases","score":0.01600000075995922,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/metabolically-healthy-obesity","display_name":"metabolically healthy obesity","score":0.9990000128746033},{"id":"https://openalex.org/keywords/childhood-obesity","display_name":"childhood obesity","score":0.6690000295639038},{"id":"https://openalex.org/keywords/adolescent-obesity","display_name":"adolescent obesity","score":0.7210000157356262},{"id":"https://openalex.org/keywords/insulin-sensitivity","display_name":"insulin sensitivity","score":0.9639999866485596},{"id":"https://openalex.org/keywords/insulin-resistance","display_name":"insulin resistance","score":0.9789999723434448},{"id":"https://openalex.org/keywords/insulin-sensitivity-index","display_name":"insulin sensitivity index","score":0.8669999837875366},{"id":"https://openalex.org/keywords/insulinogenic-index","display_name":"insulinogenic index","score":0.7440000176429749},{"id":"https://openalex.org/keywords/disposition-index","display_name":"disposition index","score":0.9779999852180481},{"id":"https://openalex.org/keywords/metabolic-syndrome","display_name":"metabolic syndrome","score":0.8019999861717224},{"id":"https://openalex.org/keywords/homa-ir","display_name":"HOMA-IR","score":0.8740000128746033},{"id":"https://openalex.org/keywords/prevalence","display_name":"prevalence","score":0.6299999952316284},{"id":"https://openalex.org/keywords/metabolic-phenotypes","display_name":"metabolic phenotypes","score":0.5759999752044678}],"concepts":[{"id":"https://openalex.org/C2777391703","wikidata":"https://www.wikidata.org/wiki/Q1053470","display_name":"Insulin resistance","level":3,"score":0.8452379107475281},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7932047843933105},{"id":"https://openalex.org/C2780586474","wikidata":"https://www.wikidata.org/wiki/Q332428","display_name":"Overweight","level":3,"score":0.7368063926696777},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6974658370018005},{"id":"https://openalex.org/C511355011","wikidata":"https://www.wikidata.org/wiki/Q12174","display_name":"Obesity","level":2,"score":0.6175333261489868},{"id":"https://openalex.org/C2780578515","wikidata":"https://www.wikidata.org/wiki/Q657193","display_name":"Metabolic syndrome","level":3,"score":0.5837755799293518},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.5494949817657471},{"id":"https://openalex.org/C2779306644","wikidata":"https://www.wikidata.org/wiki/Q2002370","display_name":"Insulin","level":2,"score":0.5416280627250671},{"id":"https://openalex.org/C72563966","wikidata":"https://www.wikidata.org/wiki/Q1303415","display_name":"Cohort","level":2,"score":0.4757884740829468}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.3390/life10080127","doi":"https://doi.org/10.3390/life10080127","is_oa":true,"landing_page_url":"https://doi.org/10.3390/life10080127","pdf_url":"https://www.mdpi.com/2075-1729/10/8/127/pdf?version=1596011257","source":{"id":"https://openalex.org/S4210200765","display_name":"Life","issn_l":"2075-1729","issn":["2075-1729"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Life","raw_type":"journal-article"},{"id":"pmid:32731619","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/32731619","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Life (Basel, Switzerland)","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:7459932","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC7459932/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Life (Basel)","raw_type":"Text"},{"id":"pmh:oai:doaj.org/article:7cf81ffb828048bea24a9ed313fa4a3a","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/7cf81ffb828048bea24a9ed313fa4a3a","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Life, Vol 10, Iss 8, p 127 (2020)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.3390/life10080127","doi":"https://doi.org/10.3390/life10080127","is_oa":true,"landing_page_url":"https://doi.org/10.3390/life10080127","pdf_url":"https://www.mdpi.com/2075-1729/10/8/127/pdf?version=1596011257","source":{"id":"https://openalex.org/S4210200765","display_name":"Life","issn_l":"2075-1729","issn":["2075-1729"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Life","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":1.0,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3045500558.pdf","grobid_xml":"https://content.openalex.org/works/W3045500558.grobid-xml"},"referenced_works_count":58,"referenced_works":["https://openalex.org/W1979249143","https://openalex.org/W1980567881","https://openalex.org/W1981229978","https://openalex.org/W1982071872","https://openalex.org/W1983287346","https://openalex.org/W1987243476","https://openalex.org/W1990781032","https://openalex.org/W1994771098","https://openalex.org/W2014004380","https://openalex.org/W2040945658","https://openalex.org/W2042657279","https://openalex.org/W2042970254","https://openalex.org/W2043843178","https://openalex.org/W2060317408","https://openalex.org/W2076609137","https://openalex.org/W2080406265","https://openalex.org/W2080720609","https://openalex.org/W2086964476","https://openalex.org/W2092014129","https://openalex.org/W2098216987","https://openalex.org/W2098914554","https://openalex.org/W2102794639","https://openalex.org/W2104129218","https://openalex.org/W2105176837","https://openalex.org/W2107653603","https://openalex.org/W2109550515","https://openalex.org/W2111053427","https://openalex.org/W2121328463","https://openalex.org/W2124395997","https://openalex.org/W2126545477","https://openalex.org/W2131723554","https://openalex.org/W2132594773","https://openalex.org/W2133795831","https://openalex.org/W2138885070","https://openalex.org/W2154750813","https://openalex.org/W2157817461","https://openalex.org/W2158418727","https://openalex.org/W2161209070","https://openalex.org/W2163710303","https://openalex.org/W2170700107","https://openalex.org/W2170728804","https://openalex.org/W2277200686","https://openalex.org/W2280075095","https://openalex.org/W2427597217","https://openalex.org/W2467844892","https://openalex.org/W2568397953","https://openalex.org/W2600258505","https://openalex.org/W2620406790","https://openalex.org/W2767053206","https://openalex.org/W2791711930","https://openalex.org/W2889417668","https://openalex.org/W2900811096","https://openalex.org/W2901168594","https://openalex.org/W2904867041","https://openalex.org/W2953845205","https://openalex.org/W2955992663","https://openalex.org/W2989749609","https://openalex.org/W3010126548"],"related_works":["https://openalex.org/W852091851","https://openalex.org/W4405965993","https://openalex.org/W2277200686","https://openalex.org/W4387433403","https://openalex.org/W3130857895","https://openalex.org/W2080406265","https://openalex.org/W7019117408","https://openalex.org/W4323661038","https://openalex.org/W3092543385","https://openalex.org/W7033380982"],"abstract_inverted_index":{"Obesity":[0],"represents":[1],"a":[2,45,168,200],"major":[3],"risk":[4],"factor":[5],"for":[6,107],"metabolic":[7,108,170,203],"disorders,":[8],"but":[9],"some":[10],"individuals,":[11],"\"metabolically":[12,25],"healthy\"":[13],"(MHO),":[14],"show":[15],"less":[16],"clinical":[17],"evidence":[18],"of":[19,31,40,47,62,104,130,156,186],"these":[20],"complications,":[21],"in":[22,44],"contrast":[23],"to":[24,36,55,115,173,189],"unhealthy\"":[26],"(MUO)":[27],"individuals.":[28,180],"The":[29,111,141],"aim":[30],"this":[32],"cross-sectional":[33],"study":[34],"is":[35],"assess":[37],"the":[38,41,60,85,105,127,131,154,184,196],"prevalence":[39],"MHO":[42,91,112,132],"phenotype":[43],"cohort":[46],"246":[48],"overweight/obese":[49],"Italian":[50],"children":[51],"and":[52,54,59,77,122,139,178],"adolescents,":[53],"evaluate":[56],"their":[57],"characteristics":[58],"role":[61],"insulin":[63,70,148,151,175,187],"resistance.":[64],"Homeostasis":[65],"model":[66],"assessment-insulin":[67],"resistance":[68],"(HOMA-IR),":[69],"sensitivity":[71,188],"index":[72,75,79],"(ISI),":[73],"insulinogenic":[74],"(IGI)":[76],"disposition":[78],"(DI)":[80],"were":[81],"all":[82],"calculated":[83],"from":[84],"Oral":[86],"Glucose":[87],"Tolerance":[88],"Test":[89],"(OGTT).":[90],"was":[92,120,126,144],"defined":[93],"by":[94],"either:":[95],"(1)":[96],"HOMA-IR":[97,157],"<":[98,159],"2.5":[99],"(MHO-IRes),":[100],"or":[101,117,150,160],"(2)":[102],"absence":[103],"criteria":[106],"syndrome":[109],"(MHO-MetS).":[110],"prevalence,":[113],"according":[114],"MHO-MetS":[116,142,165,177],"MHO-IRes":[118,138],"criteria,":[119],"37.4%":[121],"15.8%,":[123],"respectively.":[124],"ISI":[125],"strongest":[128],"predictor":[129],"phenotype,":[133],"independently":[134],"associated":[135],"with":[136,194],"both":[137,174],"MHO-MetS.":[140],"group":[143],"further":[145],"subdivided":[146],"into":[147],"sensitive":[149,164],"resistant":[152,176],"on":[153],"basis":[155],"(either":[158],"\u2265":[161],"2.5).":[162],"Insulin":[163],"patients":[166],"had":[167],"better":[169],"profile":[171],"compared":[172],"MUO-MetS":[179],"These":[181],"data":[182],"underscore":[183],"relevance":[185],"identifying,":[190],"among":[191],"young":[192],"individuals":[193],"overweight/obesity,":[195],"ones":[197],"who":[198],"have":[199],"more":[201],"favorable":[202],"phenotype.":[204]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":5},{"year":2024,"cited_by_count":5},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":4},{"year":2020,"cited_by_count":1}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2020-08-03T00:00:00"}