{"id":"https://openalex.org/W3045425141","doi":"https://doi.org/10.18632/aging.103435","title":"Lowered levels of nicotinic acetylcholine receptors and elevated apoptosis in the hippocampus of brains from patients with type 2 diabetes mellitus and db/db mice","display_name":"Lowered levels of nicotinic acetylcholine receptors and elevated apoptosis in the hippocampus of brains from patients with type 2 diabetes mellitus and db/db mice","publication_year":2020,"publication_date":"2020-07-23","ids":{"openalex":"https://openalex.org/W3045425141","doi":"https://doi.org/10.18632/aging.103435","mag":"3045425141","pmid":"https://pubmed.ncbi.nlm.nih.gov/32701482","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/7425467"},"language":"en","primary_location":{"id":"doi:10.18632/aging.103435","doi":"https://doi.org/10.18632/aging.103435","is_oa":false,"landing_page_url":"https://doi.org/10.18632/aging.103435","pdf_url":null,"source":{"id":"https://openalex.org/S4210231119","display_name":"Aging","issn_l":"1945-4589","issn":["1945-4589"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","doyens","jufo-1","ki-jl-1","medline","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310316297","host_organization_name":"Impact Journals LLC","host_organization_lineage":["https://openalex.org/P4310316297"],"host_organization_lineage_names":["Impact Journals LLC"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Aging","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/7425467","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5101755441","display_name":"Yi Xu","orcid":"https://orcid.org/0000-0001-6374-0039","observed_orcids":["https://orcid.org/0000-0001-6374-0039"]},"institutions":[{"id":"https://openalex.org/I149137203","display_name":"Guiyang Medical University","ror":"https://ror.org/035y7a716","country_code":"CN","type":"education","lineage":["https://openalex.org/I149137203"]},{"id":"https://openalex.org/I4210109381","display_name":"Affiliated Hospital of Guizhou Medical University","ror":"https://ror.org/02kstas42","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210109381"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yi Xu","raw_affiliation_strings":["Departments of Pathology at Guizhou Medical University and the Affiliated Hospital of Guizhou Medical University, Guiyang 550004, P. R. of China","Key Laboratory of Endemic and Ethnic Diseases, Guizhou Medical University of the Ministry of Education, Guiyang 550004, P. R. of China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Pathology at Guizhou Medical University and the Affiliated Hospital of Guizhou Medical University, Guiyang 550004, P. R. of China","institution_ids":["https://openalex.org/I149137203","https://openalex.org/I4210109381"]},{"raw_affiliation_string":"Key Laboratory of Endemic and Ethnic Diseases, Guizhou Medical University of the Ministry of Education, Guiyang 550004, P. R. of China","institution_ids":["https://openalex.org/I149137203"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5107253641","display_name":"Kun Cao","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I149137203","display_name":"Guiyang Medical University","ror":"https://ror.org/035y7a716","country_code":"CN","type":"education","lineage":["https://openalex.org/I149137203"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Kun Cao","raw_affiliation_strings":["Key Laboratory of Endemic and Ethnic Diseases, Guizhou Medical University of the Ministry of Education, Guiyang 550004, P. R. of China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Key Laboratory of Endemic and Ethnic Diseases, Guizhou Medical University of the Ministry of Education, Guiyang 550004, P. R. of China","institution_ids":["https://openalex.org/I149137203"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065420469","display_name":"Bing Guo","orcid":"https://orcid.org/0000-0001-8998-2597","observed_orcids":["https://orcid.org/0000-0001-8998-2597"]},"institutions":[{"id":"https://openalex.org/I149137203","display_name":"Guiyang Medical University","ror":"https://ror.org/035y7a716","country_code":"CN","type":"education","lineage":["https://openalex.org/I149137203"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Bing Guo","raw_affiliation_strings":["Department of Pathophysiology, Guizhou Medical University, Guiyang 550004, P. R. of China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathophysiology, Guizhou Medical University, Guiyang 550004, P. R. of China","institution_ids":["https://openalex.org/I149137203"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Jie Xiang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I149137203","display_name":"Guiyang Medical University","ror":"https://ror.org/035y7a716","country_code":"CN","type":"education","lineage":["https://openalex.org/I149137203"]},{"id":"https://openalex.org/I4210109381","display_name":"Affiliated Hospital of Guizhou Medical University","ror":"https://ror.org/02kstas42","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210109381"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jie Xiang","raw_affiliation_strings":["Departments of Pathology at Guizhou Medical University and the Affiliated Hospital of Guizhou Medical University, Guiyang 550004, P. R. of China","Key Laboratory of Endemic and Ethnic Diseases, Guizhou Medical University of the Ministry of Education, Guiyang 550004, P. R. of China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Pathology at Guizhou Medical University and the Affiliated Hospital of Guizhou Medical University, Guiyang 550004, P. R. of China","institution_ids":["https://openalex.org/I149137203","https://openalex.org/I4210109381"]},{"raw_affiliation_string":"Key Laboratory of Endemic and Ethnic Diseases, Guizhou Medical University of the Ministry of Education, Guiyang 550004, P. R. of China","institution_ids":["https://openalex.org/I149137203"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008242035","display_name":"Yang\u2010Ting Dong","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I149137203","display_name":"Guiyang Medical University","ror":"https://ror.org/035y7a716","country_code":"CN","type":"education","lineage":["https://openalex.org/I149137203"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yang-Ting Dong","raw_affiliation_strings":["Key Laboratory of Endemic and Ethnic Diseases, Guizhou Medical University of the Ministry of Education, Guiyang 550004, P. R. of China","Provincial Key Laboratory of Medical Molecular Biology, Guiyang 550004, P. R. of China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Key Laboratory of Endemic and Ethnic Diseases, Guizhou Medical University of the Ministry of Education, Guiyang 550004, P. R. of China","institution_ids":["https://openalex.org/I149137203"]},{"raw_affiliation_string":"Provincial Key Laboratory of Medical Molecular Biology, Guiyang 550004, P. R. of China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052598913","display_name":"Xiaolan Qi","orcid":"https://orcid.org/0000-0002-9108-6772","observed_orcids":["https://orcid.org/0000-0002-9108-6772"]},"institutions":[{"id":"https://openalex.org/I149137203","display_name":"Guiyang Medical University","ror":"https://ror.org/035y7a716","country_code":"CN","type":"education","lineage":["https://openalex.org/I149137203"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xiao-Lan Qi","raw_affiliation_strings":["Key Laboratory of Endemic and Ethnic Diseases, Guizhou Medical University of the Ministry of Education, Guiyang 550004, P. R. of China","Provincial Key Laboratory of Medical Molecular Biology, Guiyang 550004, P. R. of China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Key Laboratory of Endemic and Ethnic Diseases, Guizhou Medical University of the Ministry of Education, Guiyang 550004, P. R. of China","institution_ids":["https://openalex.org/I149137203"]},{"raw_affiliation_string":"Provincial Key Laboratory of Medical Molecular Biology, Guiyang 550004, P. R. of China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101051722","display_name":"Wenfeng Yu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I149137203","display_name":"Guiyang Medical University","ror":"https://ror.org/035y7a716","country_code":"CN","type":"education","lineage":["https://openalex.org/I149137203"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Wen-Feng Yu","raw_affiliation_strings":["Key Laboratory of Endemic and Ethnic Diseases, Guizhou Medical University of the Ministry of Education, Guiyang 550004, P. R. of China","Provincial Key Laboratory of Medical Molecular Biology, Guiyang 550004, P. R. of China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Key Laboratory of Endemic and Ethnic Diseases, Guizhou Medical University of the Ministry of Education, Guiyang 550004, P. R. of China","institution_ids":["https://openalex.org/I149137203"]},{"raw_affiliation_string":"Provincial Key Laboratory of Medical Molecular Biology, Guiyang 550004, P. R. of China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027389083","display_name":"Yan Chun Xiao","orcid":"https://orcid.org/0000-0003-4242-6387","observed_orcids":["https://orcid.org/0000-0003-4242-6387"]},"institutions":[{"id":"https://openalex.org/I149137203","display_name":"Guiyang Medical University","ror":"https://ror.org/035y7a716","country_code":"CN","type":"education","lineage":["https://openalex.org/I149137203"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yan Xiao","raw_affiliation_strings":["Key Laboratory of Endemic and Ethnic Diseases, Guizhou Medical University of the Ministry of Education, Guiyang 550004, P. R. of China","Provincial Key Laboratory of Medical Molecular Biology, Guiyang 550004, P. R. of China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Key Laboratory of Endemic and Ethnic Diseases, Guizhou Medical University of the Ministry of Education, Guiyang 550004, P. R. of China","institution_ids":["https://openalex.org/I149137203"]},{"raw_affiliation_string":"Provincial Key Laboratory of Medical Molecular Biology, Guiyang 550004, P. R. of China","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5101405656","display_name":"Zhi\u2010Zhong Guan","orcid":"https://orcid.org/0000-0001-7001-6145","observed_orcids":["https://orcid.org/0000-0001-7001-6145"]},"institutions":[{"id":"https://openalex.org/I149137203","display_name":"Guiyang Medical University","ror":"https://ror.org/035y7a716","country_code":"CN","type":"education","lineage":["https://openalex.org/I149137203"]},{"id":"https://openalex.org/I4210109381","display_name":"Affiliated Hospital of Guizhou Medical University","ror":"https://ror.org/02kstas42","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210109381"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Zhi-Zhong Guan","raw_affiliation_strings":["Departments of Pathology at Guizhou Medical University and the Affiliated Hospital of Guizhou Medical University, Guiyang 550004, P. R. of China","Key Laboratory of Endemic and Ethnic Diseases, Guizhou Medical University of the Ministry of Education, Guiyang 550004, P. R. of China","Provincial Key Laboratory of Medical Molecular Biology, Guiyang 550004, P. R. of China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Pathology at Guizhou Medical University and the Affiliated Hospital of Guizhou Medical University, Guiyang 550004, P. R. of China","institution_ids":["https://openalex.org/I149137203","https://openalex.org/I4210109381"]},{"raw_affiliation_string":"Key Laboratory of Endemic and Ethnic Diseases, Guizhou Medical University of the Ministry of Education, Guiyang 550004, P. R. of China","institution_ids":["https://openalex.org/I149137203"]},{"raw_affiliation_string":"Provincial Key Laboratory of Medical Molecular Biology, Guiyang 550004, P. R. of China","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5101405656"],"corresponding_institution_ids":["https://openalex.org/I149137203","https://openalex.org/I4210109381"],"apc_list":null,"apc_paid":null,"fwci":0.8106,"has_fulltext":false,"cited_by_count":22,"citation_normalized_percentile":{"value":0.67555549,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":93,"max":99},"biblio":{"volume":"12","issue":"14","first_page":"14205","last_page":"14218"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11818","display_name":"Nicotinic Acetylcholine Receptors Study","score":0.9746000170707703,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11818","display_name":"Nicotinic Acetylcholine Receptors Study","score":0.9746000170707703,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10086","display_name":"Alzheimer's disease research and treatments","score":0.004600000102072954,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10077","display_name":"Neuroscience and Neuropharmacology Research","score":0.0038999998942017555,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/nicotinic-acetylcholine-receptors","display_name":"nicotinic acetylcholine receptors","score":0.9900000095367432},{"id":"https://openalex.org/keywords/apoptosis","display_name":"apoptosis","score":0.9649999737739563},{"id":"https://openalex.org/keywords/hippocampus","display_name":"hippocampus","score":0.9990000128746033},{"id":"https://openalex.org/keywords/type-2-diabetes","display_name":"type 2 diabetes","score":1.0},{"id":"https://openalex.org/keywords/db-db-mice","display_name":"db/db mice","score":0.996999979019165},{"id":"https://openalex.org/keywords/cognitive-impairment","display_name":"cognitive impairment","score":0.8690000176429749},{"id":"https://openalex.org/keywords/cholinergic-dysfunction","display_name":"cholinergic dysfunction","score":0.5040000081062317}],"concepts":[{"id":"https://openalex.org/C2781161787","wikidata":"https://www.wikidata.org/wiki/Q48360","display_name":"Hippocampus","level":2,"score":0.7708830833435059},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.67582768201828},{"id":"https://openalex.org/C2775910092","wikidata":"https://www.wikidata.org/wiki/Q180623","display_name":"Acetylcholine","level":2,"score":0.666495680809021},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.647271454334259},{"id":"https://openalex.org/C80161118","wikidata":"https://www.wikidata.org/wiki/Q408520","display_name":"Acetylcholine receptor","level":3,"score":0.6259169578552246},{"id":"https://openalex.org/C2910068830","wikidata":"https://www.wikidata.org/wiki/Q3025883","display_name":"Type 2 Diabetes Mellitus","level":3,"score":0.6007985472679138},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.5830554366111755},{"id":"https://openalex.org/C188987157","wikidata":"https://www.wikidata.org/wiki/Q7030581","display_name":"Nicotinic agonist","level":3,"score":0.5488600730895996},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.49787092208862305},{"id":"https://openalex.org/C190283241","wikidata":"https://www.wikidata.org/wiki/Q14599311","display_name":"Apoptosis","level":2,"score":0.4916604161262512},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4606139659881592},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.3634703457355499},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.2856583297252655},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.24968335032463074},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.070616215467453}],"mesh":[{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001344","descriptor_name":"Autopsy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003924","descriptor_name":"Diabetes Mellitus, Type 2","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D003924","descriptor_name":"Diabetes Mellitus, Type 2","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006624","descriptor_name":"Hippocampus","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008568","descriptor_name":"Memory","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011978","descriptor_name":"Receptors, Nicotinic","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D017209","descriptor_name":"Apoptosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D018782","descriptor_name":"Maze Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D060825","descriptor_name":"Cognitive Dysfunction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D064569","descriptor_name":"alpha7 Nicotinic Acetylcholine Receptor","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D065853","descriptor_name":"Spatial Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.18632/aging.103435","doi":"https://doi.org/10.18632/aging.103435","is_oa":false,"landing_page_url":"https://doi.org/10.18632/aging.103435","pdf_url":null,"source":{"id":"https://openalex.org/S4210231119","display_name":"Aging","issn_l":"1945-4589","issn":["1945-4589"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","doyens","jufo-1","ki-jl-1","medline","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310316297","host_organization_name":"Impact Journals LLC","host_organization_lineage":["https://openalex.org/P4310316297"],"host_organization_lineage_names":["Impact Journals LLC"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Aging","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:7425467","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/7425467","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Aging (Albany NY)","raw_type":"Text"},{"id":"pmid:32701482","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/32701482","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Aging","raw_type":"Journal Article"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:7425467","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/7425467","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Aging (Albany NY)","raw_type":"Text"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9922999739646912,"id":"https://metadata.un.org/sdg/3"}],"sustainable_development_goals_aurora":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":49,"referenced_works":["https://openalex.org/W953504954","https://openalex.org/W1966945678","https://openalex.org/W1975487612","https://openalex.org/W1986529601","https://openalex.org/W1993326575","https://openalex.org/W1999647730","https://openalex.org/W2003982930","https://openalex.org/W2006090252","https://openalex.org/W2010022125","https://openalex.org/W2022587387","https://openalex.org/W2023455453","https://openalex.org/W2031635410","https://openalex.org/W2041968921","https://openalex.org/W2052765057","https://openalex.org/W2052873092","https://openalex.org/W2058838792","https://openalex.org/W2063359456","https://openalex.org/W2073387094","https://openalex.org/W2076338351","https://openalex.org/W2084453905","https://openalex.org/W2093061786","https://openalex.org/W2113200820","https://openalex.org/W2128728122","https://openalex.org/W2146310895","https://openalex.org/W2152248242","https://openalex.org/W2156326104","https://openalex.org/W2158087247","https://openalex.org/W2168261002","https://openalex.org/W2170194206","https://openalex.org/W2256552130","https://openalex.org/W2301272550","https://openalex.org/W2346810207","https://openalex.org/W2382076021","https://openalex.org/W2400423516","https://openalex.org/W2427261560","https://openalex.org/W2550283848","https://openalex.org/W2557456479","https://openalex.org/W2585714412","https://openalex.org/W2738905100","https://openalex.org/W2766455723","https://openalex.org/W2772177302","https://openalex.org/W2772650603","https://openalex.org/W2783611475","https://openalex.org/W2791011305","https://openalex.org/W2805257646","https://openalex.org/W2884987394","https://openalex.org/W2900038149","https://openalex.org/W2928918259","https://openalex.org/W2945680310"],"related_works":["https://openalex.org/W3017132474","https://openalex.org/W2765583910","https://openalex.org/W4200087947","https://openalex.org/W2074880661","https://openalex.org/W2987880364","https://openalex.org/W2031635410","https://openalex.org/W2891790496","https://openalex.org/W4304845501","https://openalex.org/W2891397432","https://openalex.org/W4308786706"],"abstract_inverted_index":{"mice,":[0],"which":[1],"might":[2],"help":[3],"explain":[4],"the":[5],"impaired":[6],"cognition":[7],"in":[8],"T2DM.":[9]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":8},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":5},{"year":2021,"cited_by_count":2}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2020-07-29T00:00:00"}