{"id":"https://openalex.org/W3045421908","doi":"https://doi.org/10.7150/ijms.48829","title":"Bactericidal and Antiproliferative Effects of Peripheral Parenteral Nutrition Solutions with Sodium Bisulfite on Pathogenic Microorganisms in Catheter Lumens","display_name":"Bactericidal and Antiproliferative Effects of Peripheral Parenteral Nutrition Solutions with Sodium Bisulfite on Pathogenic Microorganisms in Catheter Lumens","publication_year":2020,"publication_date":"2020-01-01","ids":{"openalex":"https://openalex.org/W3045421908","doi":"https://doi.org/10.7150/ijms.48829","mag":"3045421908","pmid":"https://pubmed.ncbi.nlm.nih.gov/32714086","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/7378669"},"language":"en","primary_location":{"id":"doi:10.7150/ijms.48829","doi":"https://doi.org/10.7150/ijms.48829","is_oa":true,"landing_page_url":"https://doi.org/10.7150/ijms.48829","pdf_url":"https://www.medsci.org/v17p1833.pdf","source":{"id":"https://openalex.org/S46225466","display_name":"International Journal of Medical Sciences","issn_l":"1449-1907","issn":["1449-1907"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310317973","host_organization_name":"Ivyspring International Publisher","host_organization_lineage":["https://openalex.org/P4310317973"],"host_organization_lineage_names":["Ivyspring International Publisher"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Medical Sciences","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.medsci.org/v17p1833.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5067228277","display_name":"Hiroshi Ohara","orcid":"https://orcid.org/0000-0002-0451-7440","observed_orcids":["https://orcid.org/0000-0002-0451-7440"]},"institutions":[{"id":"https://openalex.org/I30181195","display_name":"Ohu University","ror":"https://ror.org/01fe6f215","country_code":"JP","type":"education","lineage":["https://openalex.org/I30181195"]},{"id":"https://openalex.org/I4405285365","display_name":"Ohu University Hospital","ror":"https://ror.org/059njsq80","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4405285365"]}],"countries":["JP"],"is_corresponding":true,"raw_author_name":"Hiroshi Ohara","raw_affiliation_strings":["Department of Clinical Pharmacy, School of Pharmaceutical Sciences, Ohu University, 31-1 Misumido, Tomitamachi-Aza, Koriyama, Fukushima 963-8611, Japan","Department of Pharmacy, Ohu University Hospital, 31-1 Misumido, Tomitamachi-aza, Koriyama, Fukushima 963-8611, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Clinical Pharmacy, School of Pharmaceutical Sciences, Ohu University, 31-1 Misumido, Tomitamachi-Aza, Koriyama, Fukushima 963-8611, Japan","institution_ids":["https://openalex.org/I30181195"]},{"raw_affiliation_string":"Department of Pharmacy, Ohu University Hospital, 31-1 Misumido, Tomitamachi-aza, Koriyama, Fukushima 963-8611, Japan","institution_ids":["https://openalex.org/I4405285365"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077452433","display_name":"Masanori Watanabe","orcid":"https://orcid.org/0000-0003-4642-6675","observed_orcids":["https://orcid.org/0000-0003-4642-6675"]},"institutions":[{"id":"https://openalex.org/I30181195","display_name":"Ohu University","ror":"https://ror.org/01fe6f215","country_code":"JP","type":"education","lineage":["https://openalex.org/I30181195"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Masanori Watanabe","raw_affiliation_strings":["Department of Clinical Pharmacy, School of Pharmaceutical Sciences, Ohu University, 31-1 Misumido, Tomitamachi-Aza, Koriyama, Fukushima 963-8611, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Clinical Pharmacy, School of Pharmaceutical Sciences, Ohu University, 31-1 Misumido, Tomitamachi-Aza, Koriyama, Fukushima 963-8611, Japan","institution_ids":["https://openalex.org/I30181195"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083200830","display_name":"Masamu Takebayashi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I30181195","display_name":"Ohu University","ror":"https://ror.org/01fe6f215","country_code":"JP","type":"education","lineage":["https://openalex.org/I30181195"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Masamu Takebayashi","raw_affiliation_strings":["Department of Clinical Pharmacy, School of Pharmaceutical Sciences, Ohu University, 31-1 Misumido, Tomitamachi-Aza, Koriyama, Fukushima 963-8611, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Clinical Pharmacy, School of Pharmaceutical Sciences, Ohu University, 31-1 Misumido, Tomitamachi-Aza, Koriyama, Fukushima 963-8611, Japan","institution_ids":["https://openalex.org/I30181195"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Saori Abe","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I30181195","display_name":"Ohu University","ror":"https://ror.org/01fe6f215","country_code":"JP","type":"education","lineage":["https://openalex.org/I30181195"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Saori Abe","raw_affiliation_strings":["Department of Clinical Pharmacy, School of Pharmaceutical Sciences, Ohu University, 31-1 Misumido, Tomitamachi-Aza, Koriyama, Fukushima 963-8611, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Clinical Pharmacy, School of Pharmaceutical Sciences, Ohu University, 31-1 Misumido, Tomitamachi-Aza, Koriyama, Fukushima 963-8611, Japan","institution_ids":["https://openalex.org/I30181195"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Tetsuya Matsuzaki","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I30181195","display_name":"Ohu University","ror":"https://ror.org/01fe6f215","country_code":"JP","type":"education","lineage":["https://openalex.org/I30181195"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Tetsuya Matsuzaki","raw_affiliation_strings":["Department of Clinical Pharmacy, School of Pharmaceutical Sciences, Ohu University, 31-1 Misumido, Tomitamachi-Aza, Koriyama, Fukushima 963-8611, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Clinical Pharmacy, School of Pharmaceutical Sciences, Ohu University, 31-1 Misumido, Tomitamachi-Aza, Koriyama, Fukushima 963-8611, Japan","institution_ids":["https://openalex.org/I30181195"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5019421253","display_name":"Masataka Hayasaka","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I30181195","display_name":"Ohu University","ror":"https://ror.org/01fe6f215","country_code":"JP","type":"education","lineage":["https://openalex.org/I30181195"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Masataka Hayasaka","raw_affiliation_strings":["Department of Clinical Pharmacy, School of Pharmaceutical Sciences, Ohu University, 31-1 Misumido, Tomitamachi-Aza, Koriyama, Fukushima 963-8611, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Clinical Pharmacy, School of Pharmaceutical Sciences, Ohu University, 31-1 Misumido, Tomitamachi-Aza, Koriyama, Fukushima 963-8611, Japan","institution_ids":["https://openalex.org/I30181195"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5067228277"],"corresponding_institution_ids":["https://openalex.org/I30181195","https://openalex.org/I4405285365"],"apc_list":{"value":2000,"currency":"AUD","value_usd":1337},"apc_paid":{"value":2000,"currency":"AUD","value_usd":1337},"fwci":0.4908,"has_fulltext":true,"cited_by_count":7,"citation_normalized_percentile":{"value":0.63624066,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":95},"biblio":{"volume":"17","issue":"12","first_page":"1833","last_page":"1839"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10641","display_name":"Central Venous Catheters and Hemodialysis","score":0.9018999934196472,"subfield":{"id":"https://openalex.org/subfields/2706","display_name":"Critical Care and Intensive Care Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10641","display_name":"Central Venous Catheters and Hemodialysis","score":0.9018999934196472,"subfield":{"id":"https://openalex.org/subfields/2706","display_name":"Critical Care and Intensive Care Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10858","display_name":"Clinical Nutrition and Gastroenterology","score":0.07599999755620956,"subfield":{"id":"https://openalex.org/subfields/2916","display_name":"Nutrition and Dietetics"},"field":{"id":"https://openalex.org/fields/29","display_name":"Nursing"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11681","display_name":"Nosocomial Infections in ICU","score":0.0026000000070780516,"subfield":{"id":"https://openalex.org/subfields/2706","display_name":"Critical Care and Intensive Care Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/catheter-related-bloodstream-infection","display_name":"catheter-related bloodstream infection","score":0.8999999761581421},{"id":"https://openalex.org/keywords/parenteral-nutrition-solutions","display_name":"parenteral nutrition solutions","score":0.9160000085830688},{"id":"https://openalex.org/keywords/sodium-bisulfite","display_name":"sodium bisulfite","score":0.9959999918937683},{"id":"https://openalex.org/keywords/bactericidal-activity","display_name":"bactericidal activity","score":0.7870000004768372},{"id":"https://openalex.org/keywords/antiproliferative-activity","display_name":"antiproliferative activity","score":0.9359999895095825},{"id":"https://openalex.org/keywords/staphylococcus-aureus","display_name":"Staphylococcus aureus","score":0.9580000042915344},{"id":"https://openalex.org/keywords/staphylococcus-epidermidis","display_name":"Staphylococcus epidermidis","score":1.0},{"id":"https://openalex.org/keywords/pseudomonas-aeruginosa","display_name":"Pseudomonas aeruginosa","score":0.9150000214576721},{"id":"https://openalex.org/keywords/serratia-marcescens","display_name":"Serratia marcescens","score":0.9900000095367432},{"id":"https://openalex.org/keywords/bacillus-cereus","display_name":"Bacillus cereus","score":0.9950000047683716},{"id":"https://openalex.org/keywords/candida-albicans","display_name":"Candida albicans","score":0.9990000128746033},{"id":"https://openalex.org/keywords/preservatives","display_name":"preservatives","score":0.5429999828338623}],"concepts":[{"id":"https://openalex.org/C2777949923","wikidata":"https://www.wikidata.org/wiki/Q131915","display_name":"Staphylococcus epidermidis","level":4,"score":0.7855049967765808},{"id":"https://openalex.org/C2776309202","wikidata":"https://www.wikidata.org/wiki/Q140004","display_name":"Serratia marcescens","level":4,"score":0.7279442548751831},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.6801923513412476},{"id":"https://openalex.org/C2779489039","wikidata":"https://www.wikidata.org/wiki/Q188121","display_name":"Staphylococcus aureus","level":3,"score":0.6787278056144714},{"id":"https://openalex.org/C4937899","wikidata":"https://www.wikidata.org/wiki/Q68541106","display_name":"Antimicrobial","level":2,"score":0.6630649566650391},{"id":"https://openalex.org/C2777118263","wikidata":"https://www.wikidata.org/wiki/Q131307","display_name":"Bacillus cereus","level":3,"score":0.595848560333252},{"id":"https://openalex.org/C2780917455","wikidata":"https://www.wikidata.org/wiki/Q310443","display_name":"Candida albicans","level":2,"score":0.49829816818237305},{"id":"https://openalex.org/C2778883795","wikidata":"https://www.wikidata.org/wiki/Q804517","display_name":"Pathogenic bacteria","level":3,"score":0.483733206987381},{"id":"https://openalex.org/C2777637488","wikidata":"https://www.wikidata.org/wiki/Q31856","display_name":"Pseudomonas aeruginosa","level":3,"score":0.47270867228507996},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.46947181224823},{"id":"https://openalex.org/C67031304","wikidata":"https://www.wikidata.org/wiki/Q274579","display_name":"Preservative","level":2,"score":0.4610985517501831},{"id":"https://openalex.org/C2775959488","wikidata":"https://www.wikidata.org/wiki/Q407891","display_name":"Sodium bisulfite","level":2,"score":0.44461092352867126},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.42522621154785156},{"id":"https://openalex.org/C2781267111","wikidata":"https://www.wikidata.org/wiki/Q652297","display_name":"Catheter","level":2,"score":0.4142884910106659},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3375472128391266},{"id":"https://openalex.org/C31903555","wikidata":"https://www.wikidata.org/wiki/Q1637030","display_name":"Food science","level":1,"score":0.3119160532951355},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.20855379104614258},{"id":"https://openalex.org/C547475151","wikidata":"https://www.wikidata.org/wiki/Q25419","display_name":"Escherichia coli","level":3,"score":0.14786332845687866},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.13904061913490295},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.10573536157608032},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000900","descriptor_name":"Anti-Bacterial Agents","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011550","descriptor_name":"Pseudomonas aeruginosa","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D011550","descriptor_name":"Pseudomonas aeruginosa","qualifier_ui":"Q000472","qualifier_name":"pathogenicity","is_major_topic":false},{"descriptor_ui":"D012706","descriptor_name":"Serratia marcescens","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D012706","descriptor_name":"Serratia marcescens","qualifier_ui":"Q000472","qualifier_name":"pathogenicity","is_major_topic":false},{"descriptor_ui":"D013203","descriptor_name":"Staphylococcal Infections","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D013203","descriptor_name":"Staphylococcal Infections","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D013211","descriptor_name":"Staphylococcus aureus","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D013211","descriptor_name":"Staphylococcus aureus","qualifier_ui":"Q000472","qualifier_name":"pathogenicity","is_major_topic":false},{"descriptor_ui":"D013212","descriptor_name":"Staphylococcus epidermidis","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D013212","descriptor_name":"Staphylococcus epidermidis","qualifier_ui":"Q000472","qualifier_name":"pathogenicity","is_major_topic":false},{"descriptor_ui":"D013447","descriptor_name":"Sulfites","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D049109","descriptor_name":"Cell Proliferation","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D055499","descriptor_name":"Catheter-Related Infections","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D055499","descriptor_name":"Catheter-Related Infections","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D055499","descriptor_name":"Catheter-Related Infections","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D057785","descriptor_name":"Catheters","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D057947","descriptor_name":"Parenteral Nutrition Solutions","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.7150/ijms.48829","doi":"https://doi.org/10.7150/ijms.48829","is_oa":true,"landing_page_url":"https://doi.org/10.7150/ijms.48829","pdf_url":"https://www.medsci.org/v17p1833.pdf","source":{"id":"https://openalex.org/S46225466","display_name":"International Journal of Medical Sciences","issn_l":"1449-1907","issn":["1449-1907"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310317973","host_organization_name":"Ivyspring International Publisher","host_organization_lineage":["https://openalex.org/P4310317973"],"host_organization_lineage_names":["Ivyspring International Publisher"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Medical Sciences","raw_type":"journal-article"},{"id":"pmid:32714086","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/32714086","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International journal of medical sciences","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:7378669","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC7378669/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Int J Med Sci","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.7150/ijms.48829","doi":"https://doi.org/10.7150/ijms.48829","is_oa":true,"landing_page_url":"https://doi.org/10.7150/ijms.48829","pdf_url":"https://www.medsci.org/v17p1833.pdf","source":{"id":"https://openalex.org/S46225466","display_name":"International Journal of Medical Sciences","issn_l":"1449-1907","issn":["1449-1907"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310317973","host_organization_name":"Ivyspring International Publisher","host_organization_lineage":["https://openalex.org/P4310317973"],"host_organization_lineage_names":["Ivyspring International Publisher"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Medical Sciences","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9537000060081482,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3045421908.pdf","grobid_xml":"https://content.openalex.org/works/W3045421908.grobid-xml"},"referenced_works_count":43,"referenced_works":["https://openalex.org/W1443061133","https://openalex.org/W1499150574","https://openalex.org/W1518260850","https://openalex.org/W1884897797","https://openalex.org/W1931569538","https://openalex.org/W1967978808","https://openalex.org/W1969064619","https://openalex.org/W1976891952","https://openalex.org/W1979760635","https://openalex.org/W1988920387","https://openalex.org/W1999799319","https://openalex.org/W2007264623","https://openalex.org/W2015886153","https://openalex.org/W2018968442","https://openalex.org/W2025685216","https://openalex.org/W2031961961","https://openalex.org/W2059704730","https://openalex.org/W2067438848","https://openalex.org/W2073433249","https://openalex.org/W2083975748","https://openalex.org/W2084956654","https://openalex.org/W2085976672","https://openalex.org/W2093772981","https://openalex.org/W2099229982","https://openalex.org/W2109057870","https://openalex.org/W2138552859","https://openalex.org/W2140867711","https://openalex.org/W2141644886","https://openalex.org/W2150448242","https://openalex.org/W2159078156","https://openalex.org/W2165461576","https://openalex.org/W2166356134","https://openalex.org/W2170165114","https://openalex.org/W2170477641","https://openalex.org/W2171155970","https://openalex.org/W2516360153","https://openalex.org/W2744563561","https://openalex.org/W2759566861","https://openalex.org/W2806145963","https://openalex.org/W2846676492","https://openalex.org/W2947499078","https://openalex.org/W4211040424","https://openalex.org/W4300199978"],"related_works":["https://openalex.org/W2759566861","https://openalex.org/W4221050035","https://openalex.org/W1987778223","https://openalex.org/W2802755311","https://openalex.org/W2800201987","https://openalex.org/W3217330186","https://openalex.org/W2085976672","https://openalex.org/W2022835493","https://openalex.org/W2969795499","https://openalex.org/W2274729859"],"abstract_inverted_index":{"Catheter-related":[0],"bloodstream":[1],"infections":[2],"(CRBSIs)":[3],"due":[4],"to":[5,12,250],"pathogenic":[6,29,73,108],"microorganisms":[7,74,227],"pose":[8],"a":[9,52,87,94,131,160,199,215],"major":[10],"threat":[11],"patients":[13,233,237],"requiring":[14],"parenteral":[15],"nutrition":[16,63],"(PN).Additives":[17],"contained":[18],"in":[19,149,155,159,190,228,245],"medicines":[20],"and":[21,25,68,96,126,137,165,187,194,222,236],"foods":[22],"have":[23,37,44,220],"antiproliferative":[24,201],"bacteriostatic":[26],"effects":[27,71,177,225],"on":[28,48,72,178,203,226],"microorganisms.Therefore,":[30],"PN":[31,53,211],"solutions":[32,64,212],"containing":[33],"additives":[34],"may":[35],"also":[36],"an":[38,99],"antibacterial":[39,140],"effect.However,":[40],"so":[41],"far,":[42],"there":[43],"been":[45],"no":[46],"reports":[47],"or":[49],"observations":[50],"of":[51,90,114,142,232],"solution":[54],"with":[55,65,234,238],"bactericidal":[56,176,221],"activity.In":[57],"this":[58,102],"study,":[59,103],"we":[60,104,144,171,206],"assessed":[61],"several":[62],"antimicrobial":[66,100],"activities":[67],"investigated":[69],"their":[70],"colonizing":[75],"catheter":[76,132,157,192,230],"lumens.We":[77],"selected":[78],"the":[79,106,111,139,150,156,168,191,229,252],"highly":[80,209],"acidic":[81,210],"Plas-Amino":[82],"\u00ae":[83],"(PA),":[84],"which":[85],"contains":[86],"large":[88],"amount":[89],"sodium":[91,218],"bisulfite":[92,219],"as":[93,110],"preservative":[95,216],"potentially":[97],"has":[98,175,198],"effect.In":[101],"used":[105],"following":[107],"bacteria":[109,148],"main":[112],"causatives":[113],"CRBSIs:":[115],"Staphylococcus":[116,118],"aureus,":[117,180],"epidermidis,":[119,182],"Bacillus":[120],"cereus,":[121,184],"Serratia":[122],"marcescens,":[123,186],"Pseudomonas":[124],"aeruginosa,":[125],"Candida":[127],"albicans.We":[128],"then":[129],"created":[130],"lumen":[133,158,193],"microorganism":[134],"contamination":[135],"model":[136],"evaluated":[138],"effect":[141,202],"PA;":[143],"found":[145],"that":[146,173,196,208,213],"all":[147],"control":[151],"group":[152],"grew":[153],"significantly":[154],"time-dependent":[161],"manner":[162],"at":[163],"48":[164],"72":[166],"h.On":[167],"other":[169],"hand,":[170],"demonstrated":[172],"PA":[174],"S.":[179,181,185],"B.":[183],"P.":[188],"aeruginosa":[189],"confirmed":[195],"it":[197,247],"remarkable":[200],"C.":[204],"albicans.Hence,":[205],"concluded":[207],"contain":[214],"like":[217],"growth":[223],"inhibition":[224],"lumens":[231],"CRBSIs":[235],"totally":[239],"implantable":[240],"central":[241],"venous":[242],"access":[243],"devices,":[244],"whom":[246],"is":[248],"difficult":[249],"remove":[251],"catheter.":[253]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":2}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2020-07-29T00:00:00"}