{"id":"https://openalex.org/W3045316490","doi":"https://doi.org/10.1186/s12879-020-05243-9","title":"Impact of GeneXpert MTB/RIF\u00ae on treatment initiation and outcomes of RIF-resistant and RIF-susceptible TB patients in Vladimir TB dispensary, Russia","display_name":"Impact of GeneXpert MTB/RIF\u00ae on treatment initiation and outcomes of RIF-resistant and RIF-susceptible TB patients in Vladimir TB dispensary, Russia","publication_year":2020,"publication_date":"2020-07-25","ids":{"openalex":"https://openalex.org/W3045316490","doi":"https://doi.org/10.1186/s12879-020-05243-9","mag":"3045316490","pmid":"https://pubmed.ncbi.nlm.nih.gov/32711457","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/7382080"},"language":"en","primary_location":{"id":"doi:10.1186/s12879-020-05243-9","doi":"https://doi.org/10.1186/s12879-020-05243-9","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12879-020-05243-9","pdf_url":"https://bmcinfectdis.biomedcentral.com/track/pdf/10.1186/s12879-020-05243-9","source":{"id":"https://openalex.org/S171015910","display_name":"BMC Infectious Diseases","issn_l":"1471-2334","issn":["1471-2334"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Infectious Diseases","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://bmcinfectdis.biomedcentral.com/track/pdf/10.1186/s12879-020-05243-9","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5066370166","display_name":"Julia V. Ershova","orcid":"https://orcid.org/0000-0003-3873-7166","observed_orcids":["https://orcid.org/0000-0003-3873-7166"]},"institutions":[{"id":"https://openalex.org/I1289490764","display_name":"Centers for Disease Control and Prevention","ror":"https://ror.org/042twtr12","country_code":"US","type":"government","lineage":["https://openalex.org/I1289490764","https://openalex.org/I1299022934"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Julia V. Ershova","raw_affiliation_strings":["U.S. Centers for Disease Control and Prevention, Atlanta, GA, USA. jhe3@cdc.gov","U.S. Centers for Disease Control and Prevention, Atlanta, GA, USA"],"raw_orcid":"https://orcid.org/0000-0003-3873-7166","affiliations":[{"raw_affiliation_string":"U.S. Centers for Disease Control and Prevention, Atlanta, GA, USA. jhe3@cdc.gov","institution_ids":["https://openalex.org/I1289490764"]},{"raw_affiliation_string":"U.S. Centers for Disease Control and Prevention, Atlanta, GA, USA","institution_ids":["https://openalex.org/I1289490764"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016400476","display_name":"Grigory V. Volchenkov","orcid":"https://orcid.org/0000-0002-3416-6477","observed_orcids":["https://orcid.org/0000-0002-3416-6477"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Grigory V. Volchenkov","raw_affiliation_strings":["Vladimir Oblast TB Dispensary, Vladimir, Russia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Vladimir Oblast TB Dispensary, Vladimir, Russia","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048504045","display_name":"Tatiana R. Somova","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Tatiana R. Somova","raw_affiliation_strings":["Vladimir Oblast TB Dispensary, Vladimir, Russia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Vladimir Oblast TB Dispensary, Vladimir, Russia","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103918255","display_name":"Tatiana A. Kuznetsova","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Tatiana A. Kuznetsova","raw_affiliation_strings":["Vladimir Oblast TB Dispensary, Vladimir, Russia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Vladimir Oblast TB Dispensary, Vladimir, Russia","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5004186847","display_name":"Natalia V. Kaunetis","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Natalia V. Kaunetis","raw_affiliation_strings":["Vladimir Oblast TB Dispensary, Vladimir, Russia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Vladimir Oblast TB Dispensary, Vladimir, Russia","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112552212","display_name":"Dorothy A. Kaminski","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1289490764","display_name":"Centers for Disease Control and Prevention","ror":"https://ror.org/042twtr12","country_code":"US","type":"government","lineage":["https://openalex.org/I1289490764","https://openalex.org/I1299022934"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Dorothy Kaminski","raw_affiliation_strings":["U.S. Centers for Disease Control and Prevention, Atlanta, GA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"U.S. Centers for Disease Control and Prevention, Atlanta, GA, USA","institution_ids":["https://openalex.org/I1289490764"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061994881","display_name":"Olga V. Demikhova","orcid":"https://orcid.org/0000-0002-3843-9911","observed_orcids":["https://orcid.org/0000-0002-3843-9911"]},"institutions":[{"id":"https://openalex.org/I4210141872","display_name":"Central Scientific Research Institute of Tuberculosis Russian Academy of Medical Sciences","ror":"https://ror.org/03z90hq89","country_code":"RU","type":"facility","lineage":["https://openalex.org/I1313323035","https://openalex.org/I1318325419","https://openalex.org/I4210110862","https://openalex.org/I4210141872"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"Olga V. Demikhova","raw_affiliation_strings":["Central Tuberculosis Research Institute, Moscow, Russia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Central Tuberculosis Research Institute, Moscow, Russia","institution_ids":["https://openalex.org/I4210141872"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071518085","display_name":"\u041b\u0430\u0440\u0438\u0441\u0430 \u041d\u0438\u043a\u043e\u043b\u0430\u0435\u0432\u043d\u0430 \u0427\u0435\u0440\u043d\u043e\u0443\u0441\u043e\u0432\u0430","orcid":"https://orcid.org/0000-0001-6288-7549","observed_orcids":["https://orcid.org/0000-0001-6288-7549"]},"institutions":[{"id":"https://openalex.org/I4210141872","display_name":"Central Scientific Research Institute of Tuberculosis Russian Academy of Medical Sciences","ror":"https://ror.org/03z90hq89","country_code":"RU","type":"facility","lineage":["https://openalex.org/I1313323035","https://openalex.org/I1318325419","https://openalex.org/I4210110862","https://openalex.org/I4210141872"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"Larisa N. Chernousova","raw_affiliation_strings":["Central Tuberculosis Research Institute, Moscow, Russia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Central Tuberculosis Research Institute, Moscow, Russia","institution_ids":["https://openalex.org/I4210141872"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060693254","display_name":"Irina A Vasilyeva","orcid":"https://orcid.org/0000-0002-0637-7955","observed_orcids":["https://orcid.org/0000-0002-0637-7955"]},"institutions":[{"id":"https://openalex.org/I4210141872","display_name":"Central Scientific Research Institute of Tuberculosis Russian Academy of Medical Sciences","ror":"https://ror.org/03z90hq89","country_code":"RU","type":"facility","lineage":["https://openalex.org/I1313323035","https://openalex.org/I1318325419","https://openalex.org/I4210110862","https://openalex.org/I4210141872"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"Irina A. Vasilyeva","raw_affiliation_strings":["Central Tuberculosis Research Institute, Moscow, Russia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Central Tuberculosis Research Institute, Moscow, Russia","institution_ids":["https://openalex.org/I4210141872"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5088299133","display_name":"Eleanor M. Kerr","orcid":"https://orcid.org/0000-0001-9390-4655","observed_orcids":["https://orcid.org/0000-0001-9390-4655"]},"institutions":[{"id":"https://openalex.org/I150468666","display_name":"Emory University","ror":"https://ror.org/03czfpz43","country_code":"US","type":"education","lineage":["https://openalex.org/I150468666"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Eleanor M. Kerr","raw_affiliation_strings":["Emory University, Atlanta, GA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Emory University, Atlanta, GA, USA","institution_ids":["https://openalex.org/I150468666"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053266095","display_name":"J. Peter Cegielski","orcid":"https://orcid.org/0000-0003-2647-4354","observed_orcids":["https://orcid.org/0000-0003-2647-4354"]},"institutions":[{"id":"https://openalex.org/I1289490764","display_name":"Centers for Disease Control and Prevention","ror":"https://ror.org/042twtr12","country_code":"US","type":"government","lineage":["https://openalex.org/I1289490764","https://openalex.org/I1299022934"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"J. Peter Cegielski","raw_affiliation_strings":["U.S. Centers for Disease Control and Prevention, Atlanta, GA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"U.S. Centers for Disease Control and Prevention, Atlanta, GA, USA","institution_ids":["https://openalex.org/I1289490764"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5102955604","display_name":"Ekaterina V. Kurbatova","orcid":"https://orcid.org/0000-0003-4636-3731","observed_orcids":["https://orcid.org/0000-0003-4636-3731"]},"institutions":[{"id":"https://openalex.org/I1289490764","display_name":"Centers for Disease Control and Prevention","ror":"https://ror.org/042twtr12","country_code":"US","type":"government","lineage":["https://openalex.org/I1289490764","https://openalex.org/I1299022934"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ekaterina V. Kurbatova","raw_affiliation_strings":["U.S. Centers for Disease Control and Prevention, Atlanta, GA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"U.S. Centers for Disease Control and Prevention, Atlanta, GA, USA","institution_ids":["https://openalex.org/I1289490764"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5066370166"],"corresponding_institution_ids":["https://openalex.org/I1289490764"],"apc_list":{"value":2290,"currency":"USD","value_usd":2290},"apc_paid":{"value":2290,"currency":"USD","value_usd":2290},"fwci":0.2199,"has_fulltext":true,"cited_by_count":15,"citation_normalized_percentile":{"value":0.67949547,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":91,"max":97},"biblio":{"volume":"20","issue":"1","first_page":"543","last_page":"543"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10038","display_name":"Tuberculosis Research and Epidemiology","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10038","display_name":"Tuberculosis Research and Epidemiology","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11381","display_name":"Infectious Diseases and Tuberculosis","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11316","display_name":"Mycobacterium research and diagnosis","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/xpert-mtb-rif","display_name":"Xpert MTB/RIF","score":0.9959999918937683},{"id":"https://openalex.org/keywords/rifampicin-resistant-tuberculosis","display_name":"rifampicin-resistant tuberculosis","score":0.871999979019165},{"id":"https://openalex.org/keywords/tuberculosis-diagnosis","display_name":"tuberculosis diagnosis","score":0.5619999766349792},{"id":"https://openalex.org/keywords/treatment-outcomes","display_name":"treatment outcomes","score":0.847000002861023},{"id":"https://openalex.org/keywords/time-to-treatment","display_name":"time to treatment","score":0.8080000281333923},{"id":"https://openalex.org/keywords/molecular-diagnosis","display_name":"molecular diagnosis","score":0.6119999885559082},{"id":"https://openalex.org/keywords/tuberculosis-dispensaries","display_name":"tuberculosis dispensaries","score":0.6079999804496765},{"id":"https://openalex.org/keywords/drug-resistant-tuberculosis","display_name":"drug-resistant tuberculosis","score":0.5070000290870667},{"id":"https://openalex.org/keywords/tuberculosis-transmission-prevention","display_name":"tuberculosis transmission prevention","score":0.5759999752044678},{"id":"https://openalex.org/keywords/smear-negative-pulmonary-tuberculosis","display_name":"smear-negative tuberculosis","score":0.5249999761581421},{"id":"https://openalex.org/keywords/smear-positive-pulmonary-tuberculosis","display_name":"smear-positive tuberculosis","score":0.5979999899864197},{"id":"https://openalex.org/keywords/drug-susceptibility-testing","display_name":"drug susceptibility testing","score":0.5419999957084656}],"concepts":[{"id":"https://openalex.org/C2775959389","wikidata":"https://www.wikidata.org/wiki/Q688829","display_name":"Dispensary","level":2,"score":0.9053663015365601},{"id":"https://openalex.org/C126265401","wikidata":"https://www.wikidata.org/wiki/Q295544","display_name":"GeneXpert MTB/RIF","level":4,"score":0.8740571737289429},{"id":"https://openalex.org/C190139176","wikidata":"https://www.wikidata.org/wiki/Q598976","display_name":"Medical microbiology","level":2,"score":0.8368849754333496},{"id":"https://openalex.org/C190612196","wikidata":"https://www.wikidata.org/wiki/Q180502","display_name":"Parasitology","level":2,"score":0.6792987585067749},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5788773894309998},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.5480917692184448},{"id":"https://openalex.org/C185032368","wikidata":"https://www.wikidata.org/wiki/Q1365243","display_name":"Tropical medicine","level":2,"score":0.5261844396591187},{"id":"https://openalex.org/C2781069245","wikidata":"https://www.wikidata.org/wiki/Q12204","display_name":"Tuberculosis","level":2,"score":0.43708330392837524},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.3232388496398926},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3161168694496155},{"id":"https://openalex.org/C512399662","wikidata":"https://www.wikidata.org/wiki/Q3505712","display_name":"Family medicine","level":1,"score":0.22708511352539062},{"id":"https://openalex.org/C2777975735","wikidata":"https://www.wikidata.org/wiki/Q130971","display_name":"Mycobacterium tuberculosis","level":3,"score":0.1938529908657074},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.09418249130249023}],"mesh":[{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000904","descriptor_name":"Antibiotics, Antitubercular","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D004269","descriptor_name":"DNA, Bacterial","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008826","descriptor_name":"Microbial Sensitivity Tests","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009154","descriptor_name":"Mutation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009169","descriptor_name":"Mycobacterium tuberculosis","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D011446","descriptor_name":"Prospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012293","descriptor_name":"Rifampin","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D012426","descriptor_name":"Russia","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018088","descriptor_name":"Tuberculosis, Multidrug-Resistant","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D018088","descriptor_name":"Tuberculosis, Multidrug-Resistant","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D018088","descriptor_name":"Tuberculosis, Multidrug-Resistant","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D021141","descriptor_name":"Nucleic Acid Amplification Techniques","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D024881","descriptor_name":"Drug Resistance, Bacterial","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D055815","descriptor_name":"Young Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D061665","descriptor_name":"Time-to-Treatment","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.1186/s12879-020-05243-9","doi":"https://doi.org/10.1186/s12879-020-05243-9","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12879-020-05243-9","pdf_url":"https://bmcinfectdis.biomedcentral.com/track/pdf/10.1186/s12879-020-05243-9","source":{"id":"https://openalex.org/S171015910","display_name":"BMC Infectious Diseases","issn_l":"1471-2334","issn":["1471-2334"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Infectious Diseases","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:7382080","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/7382080","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Infect Dis","raw_type":"Text"},{"id":"pmid:32711457","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/32711457","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC infectious diseases","raw_type":"Journal Article"},{"id":"pmh:oai:doaj.org/article:86f88f08025e43cd9740d3c00a5f6273","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/86f88f08025e43cd9740d3c00a5f6273","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Infectious Diseases, Vol 20, Iss 1, Pp 1-9 (2020)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1186/s12879-020-05243-9","doi":"https://doi.org/10.1186/s12879-020-05243-9","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12879-020-05243-9","pdf_url":"https://bmcinfectdis.biomedcentral.com/track/pdf/10.1186/s12879-020-05243-9","source":{"id":"https://openalex.org/S171015910","display_name":"BMC Infectious Diseases","issn_l":"1471-2334","issn":["1471-2334"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Infectious Diseases","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":1.0}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320306115","display_name":"United States Agency for International Development","ror":"https://ror.org/01n6e6j62"},{"id":"https://openalex.org/F4320310979","display_name":"U.S. President\u2019s Emergency Plan for AIDS Relief","ror":"https://ror.org/025g6sc95"},{"id":"https://openalex.org/F4320332162","display_name":"Centers for Disease Control and Prevention","ror":"https://ror.org/042twtr12"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3045316490.pdf","grobid_xml":"https://content.openalex.org/works/W3045316490.grobid-xml"},"referenced_works_count":10,"referenced_works":["https://openalex.org/W1994666903","https://openalex.org/W2044132732","https://openalex.org/W2107158674","https://openalex.org/W2179548014","https://openalex.org/W2321264330","https://openalex.org/W2412236122","https://openalex.org/W2424201562","https://openalex.org/W2530454359","https://openalex.org/W2895784427","https://openalex.org/W2948492785"],"related_works":["https://openalex.org/W579183227","https://openalex.org/W2932065890","https://openalex.org/W2412236122","https://openalex.org/W2269195022","https://openalex.org/W2117350133","https://openalex.org/W7010445935","https://openalex.org/W2424201562","https://openalex.org/W2321264330","https://openalex.org/W7135076306","https://openalex.org/W2044132732"],"abstract_inverted_index":{"BACKGROUND:":[0],"The":[1,185,235],"main":[2],"advantage":[3],"of":[4,15,28,36,48,68,78,301,323,333,339,345,347,350],"GeneXpert":[5,69],"MTB/RIF\u00ae":[6,70],"(Xpert)":[7],"molecular":[8],"diagnostic":[9,71,102],"technology":[10,103],"is":[11,335],"the":[12,37,107,131,137,161,207,258,308,317],"rapid":[13,324],"detection":[14],"M.tuberculosis":[16],"DNA":[17],"and":[18,45,50,55,65,92,119,124,343],"mutations":[19],"associated":[20],"with":[21,152,166,212,273],"rifampicin":[22],"(RIF)":[23],"resistance":[24],"for":[25,144,188,303,313,337],"timely":[26],"initiation":[27,44,135,193,252],"appropriate":[29,340],"treatment":[30,43,46,115,134,165,192,214,251,274,312,329,341],"and,":[31],"consequently,":[32],"preventing":[33],"further":[34],"transmission":[35,346],"disease.":[38],"We":[39,109,297],"assessed":[40],"time":[41,132,189,249,309],"to":[42,113,129,133,190,203,250,310],"outcomes":[47,116,220],"RIF-resistant":[49,158,209,314],"RIF-susceptible":[51,246,270],"TB":[52,59,80,145,153,210,247,271,319],"patients":[53,76,142,159,211,315],"diagnosed":[54,151],"treated":[56],"in":[57,62,106,117,160,173,197,226,232,285,291,316],"Vladimir":[58,318],"Dispensary,":[60],"Russia":[61],"2012,":[63,148],"before":[64],"after":[66],"implementation":[67,322],"technology.":[72],"METHODS:":[73],"All":[74],"adult":[75],"suspected":[77],"having":[79],"during":[81,146],"February-December":[82,147],"2012":[83,100],"underwent":[84],"a":[85],"clinical":[86],"examination,":[87],"chest":[88],"x-ray,":[89],"microscopy,":[90],"culture,":[91],"phenotypic":[93],"drug":[94],"susceptibility":[95],"testing":[96],"(DST).":[97],"Starting":[98],"August":[99],"Xpert":[101,302],"became":[104],"available":[105,213],"facility.":[108],"used":[110,128],"logistic":[111],"regression":[112],"compare":[114,130],"pre-Xpert":[118,174,204,233,292],"post-Xpert":[120,162,198,227,286],"periods.":[121],"Kaplan-Meier":[122],"curves":[123],"log-rank":[125],"test":[126],"were":[127,150],"between":[136,257],"groups.":[138],"RESULTS:":[139],"Of":[140,268],"402":[141],"screened":[143],"338":[149],"(280":[154],"RIF-susceptible,":[155],"58":[156],"RIF-resistant).":[157],"group":[163,175,199,228,287,293],"started":[164],"second-line":[167],"drugs":[168],"(SLD)":[169],"earlier":[170],"than":[171],"those":[172],"(median":[176],"11":[177],"vs.":[178,261],"37":[179],"days,":[180,263],"Log-rank":[181,264],"p":[182,265],"=":[183,266],"0.02).":[184],"hazard":[186],"ratio":[187],"SLD":[191,311],"was":[194,239,253],"significantly":[195,255,306],"higher":[196],"(HR:2.06;":[200],"95%CI:1.09,3.89)":[201],"compared":[202],"group.":[205,234],"Among":[206,245],"53/58":[208],"outcome,":[215,275],"28":[216],"(53%)":[217],"had":[218,279],"successful":[219,280],"(cured/completed":[221],"treatment)":[222],"including":[223,282],"15/26":[224],"(58%)":[225],"versus":[229,288],"13/27":[230],"(48%)":[231],"observed":[236,298],"difference,":[237],"however,":[238],"not":[240,254,327],"statistically":[241],"significant":[242],"(OR:0.69;":[243],"95%CI:0.23,2.06).":[244],"cases":[248,272,278],"different":[256],"groups":[259],"(2":[260],"3":[262],"0.73).":[267],"252/280":[269],"199":[276],"(79%)":[277],"outcome":[281],"94/114":[283],"(82%)":[284],"105/138":[289],"(76%)":[290],"(OR:0.68;":[294],"95%CI:0.36,1.26).":[295],"CONCLUSION:":[296],"that":[299],"availability":[300],"initial":[304],"diagnosis":[305,332],"reduced":[307],"Dispensary.":[320],"Although":[321],"diagnostics":[325],"did":[326],"improve":[328],"outcomes,":[330],"early":[331],"MDR-TB":[334],"important":[336],"selection":[338],"regimen":[342],"prevention":[344],"drug-resistant":[348],"strains":[349],"TB.":[351]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":4},{"year":2024,"cited_by_count":4},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":3}],"updated_date":"2026-11-08T12:12:28.789561","created_date":"2020-07-29T00:00:00"}