{"id":"https://openalex.org/W3045150550","doi":null,"title":"Emerging concepts in metabolically healthy obesity.","display_name":"Emerging concepts in metabolically healthy obesity.","publication_year":2020,"publication_date":"2020-01-01","ids":{"openalex":"https://openalex.org/W3045150550","mag":"3045150550","pmid":"https://pubmed.ncbi.nlm.nih.gov/32685263","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/7364278"},"language":"en","primary_location":{"id":"pmh:oai:pubmedcentral.nih.gov:7364278","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/7364278","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Am J Cardiovasc Dis","raw_type":"Text"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/7364278","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5025911237","display_name":"Alice Pereira Duque","orcid":"https://orcid.org/0000-0003-0325-9424","observed_orcids":["https://orcid.org/0000-0003-0325-9424"]},"institutions":[{"id":"https://openalex.org/I4210106620","display_name":"Instituto Nacional de Cardiologia","ror":"https://ror.org/01fjcgc06","country_code":"BR","type":"healthcare","lineage":["https://openalex.org/I4210106620"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Alice P Duque","raw_affiliation_strings":["Department of Research and Education, National Institute of Cardiology Rio de Janeiro, RJ, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Research and Education, National Institute of Cardiology Rio de Janeiro, RJ, Brazil","institution_ids":["https://openalex.org/I4210106620"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102860404","display_name":"Luiz Fernando Rodrigues","orcid":"https://orcid.org/0000-0001-7007-7431","observed_orcids":["https://orcid.org/0000-0001-7007-7431"]},"institutions":[{"id":"https://openalex.org/I4210106620","display_name":"Instituto Nacional de Cardiologia","ror":"https://ror.org/01fjcgc06","country_code":"BR","type":"healthcare","lineage":["https://openalex.org/I4210106620"]},{"id":"https://openalex.org/I83648350","display_name":"Universidade Federal do Estado do Rio de Janeiro","ror":"https://ror.org/04tec8z30","country_code":"BR","type":"education","lineage":["https://openalex.org/I83648350"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Luiz F Rodrigues Junior","raw_affiliation_strings":["Department of Research and Education, National Institute of Cardiology Rio de Janeiro, RJ, Brazil","Department of Physiological Sciences, Biomedical Institute, Federal University of The State of Rio de Janeiro Rio de Janeiro, RJ, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Research and Education, National Institute of Cardiology Rio de Janeiro, RJ, Brazil","institution_ids":["https://openalex.org/I4210106620"]},{"raw_affiliation_string":"Department of Physiological Sciences, Biomedical Institute, Federal University of The State of Rio de Janeiro Rio de Janeiro, RJ, Brazil","institution_ids":["https://openalex.org/I83648350"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009787805","display_name":"Mauro Felippe Felix Mediano","orcid":"https://orcid.org/0000-0001-6369-3631","observed_orcids":["https://orcid.org/0000-0001-6369-3631"]},"institutions":[{"id":"https://openalex.org/I4210106620","display_name":"Instituto Nacional de Cardiologia","ror":"https://ror.org/01fjcgc06","country_code":"BR","type":"healthcare","lineage":["https://openalex.org/I4210106620"]},{"id":"https://openalex.org/I4405286924","display_name":"Instituto Nacional de Infectologia Evandro Chagas","ror":"https://ror.org/03jw34240","country_code":"BR","type":"healthcare","lineage":["https://openalex.org/I4405286924","https://openalex.org/I52325"]},{"id":"https://openalex.org/I52325","display_name":"Funda\u00e7\u00e3o Oswaldo Cruz","ror":"https://ror.org/04jhswv08","country_code":"BR","type":"facility","lineage":["https://openalex.org/I52325"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Mauro F F Mediano","raw_affiliation_strings":["Department of Research and Education, National Institute of Cardiology Rio de Janeiro, RJ, Brazil","Evandro Chagas National Institute of Infectious Disease, Oswaldo Cruz Foundation Rio de Janeiro, RJ, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Research and Education, National Institute of Cardiology Rio de Janeiro, RJ, Brazil","institution_ids":["https://openalex.org/I4210106620"]},{"raw_affiliation_string":"Evandro Chagas National Institute of Infectious Disease, Oswaldo Cruz Foundation Rio de Janeiro, RJ, Brazil","institution_ids":["https://openalex.org/I4405286924","https://openalex.org/I52325"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062155006","display_name":"Eduardo Vera Tibiri\u00e7\u00e1","orcid":"https://orcid.org/0000-0002-3406-9300","observed_orcids":["https://orcid.org/0000-0002-3406-9300"]},"institutions":[{"id":"https://openalex.org/I4210106620","display_name":"Instituto Nacional de Cardiologia","ror":"https://ror.org/01fjcgc06","country_code":"BR","type":"healthcare","lineage":["https://openalex.org/I4210106620"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Eduardo Tibiri\u00e7a","raw_affiliation_strings":["Department of Research and Education, National Institute of Cardiology Rio de Janeiro, RJ, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Research and Education, National Institute of Cardiology Rio de Janeiro, RJ, Brazil","institution_ids":["https://openalex.org/I4210106620"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5101613477","display_name":"Andrea De Lorenzo","orcid":"https://orcid.org/0000-0001-8522-6612","observed_orcids":["https://orcid.org/0000-0001-8522-6612"]},"institutions":[{"id":"https://openalex.org/I4210106620","display_name":"Instituto Nacional de Cardiologia","ror":"https://ror.org/01fjcgc06","country_code":"BR","type":"healthcare","lineage":["https://openalex.org/I4210106620"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Andrea De Lorenzo","raw_affiliation_strings":["Department of Research and Education, National Institute of Cardiology Rio de Janeiro, RJ, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Research and Education, National Institute of Cardiology Rio de Janeiro, RJ, Brazil","institution_ids":["https://openalex.org/I4210106620"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.9807,"has_fulltext":false,"cited_by_count":23,"citation_normalized_percentile":{"value":0.8678987,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":91,"max":98},"biblio":{"volume":"10","issue":"2","first_page":"48","last_page":"61"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10027","display_name":"Diabetes, Cardiovascular Risks, and Lipoproteins","score":0.8428000211715698,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10027","display_name":"Diabetes, Cardiovascular Risks, and Lipoproteins","score":0.8428000211715698,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10528","display_name":"Adipokines, Inflammation, and Metabolic Diseases","score":0.07940000295639038,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12979","display_name":"Cardiovascular Disease and Adiposity","score":0.053199999034404755,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/metabolically-healthy-obesity","display_name":"metabolically healthy obesity","score":1.0},{"id":"https://openalex.org/keywords/obesity-phenotypes","display_name":"obesity phenotypes","score":0.6669999957084656},{"id":"https://openalex.org/keywords/cardiovascular-risk","display_name":"cardiovascular risk","score":0.9309999942779541},{"id":"https://openalex.org/keywords/subclinical-cardiovascular-disease","display_name":"subclinical cardiovascular disease","score":0.8709999918937683},{"id":"https://openalex.org/keywords/cytokines","display_name":"cytokines","score":0.6930000185966492},{"id":"https://openalex.org/keywords/hormones","display_name":"hormones","score":0.8500000238418579},{"id":"https://openalex.org/keywords/insulin-resistance","display_name":"insulin resistance","score":0.7080000042915344},{"id":"https://openalex.org/keywords/metabolic-syndrome","display_name":"metabolic syndrome","score":0.8420000076293945},{"id":"https://openalex.org/keywords/non-communicable-diseases","display_name":"non-communicable diseases","score":0.7870000004768372}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8479866981506348},{"id":"https://openalex.org/C2778096610","wikidata":"https://www.wikidata.org/wiki/Q1476525","display_name":"Dyslipidemia","level":3,"score":0.7725058197975159},{"id":"https://openalex.org/C511355011","wikidata":"https://www.wikidata.org/wiki/Q12174","display_name":"Obesity","level":2,"score":0.7462562322616577},{"id":"https://openalex.org/C2780578515","wikidata":"https://www.wikidata.org/wiki/Q657193","display_name":"Metabolic syndrome","level":3,"score":0.6453475952148438},{"id":"https://openalex.org/C113280763","wikidata":"https://www.wikidata.org/wiki/Q2326546","display_name":"Subclinical infection","level":2,"score":0.5666216611862183},{"id":"https://openalex.org/C2777391703","wikidata":"https://www.wikidata.org/wiki/Q1053470","display_name":"Insulin resistance","level":3,"score":0.5596731901168823},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.5556693077087402},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.49274876713752747},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.4846935570240021},{"id":"https://openalex.org/C50440223","wikidata":"https://www.wikidata.org/wiki/Q1475848","display_name":"Risk factor","level":2,"score":0.45275330543518066},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.43814489245414734},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.34511950612068176},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.2385583221912384},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.07416623830795288}],"mesh":[],"locations_count":4,"locations":[{"id":"pmh:oai:pubmedcentral.nih.gov:7364278","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/7364278","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Am J Cardiovasc Dis","raw_type":"Text"},{"id":"pmid:32685263","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/32685263","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American journal of cardiovascular disease","raw_type":"Journal Article"},{"id":"pmh:oai:arca.fiocruz.br:icict/51882","doi":null,"is_oa":true,"landing_page_url":"https://arca.fiocruz.br/handle/icict/51882","pdf_url":null,"source":{"id":"https://openalex.org/S7407055450","display_name":"Arca - Reposit\u00f3rio Institucional da Fiocruz","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"journal article"},{"id":"mag:3045150550","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/32685263","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:7364278","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/7364278","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Am J Cardiovasc Dis","raw_type":"Text"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":1.0}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":102,"referenced_works":["https://openalex.org/W1509738237","https://openalex.org/W1537559277","https://openalex.org/W1579954813","https://openalex.org/W1592700349","https://openalex.org/W1860497814","https://openalex.org/W1896800875","https://openalex.org/W1914931275","https://openalex.org/W1935184657","https://openalex.org/W1952359548","https://openalex.org/W1979249143","https://openalex.org/W1981383216","https://openalex.org/W1988527243","https://openalex.org/W1988568259","https://openalex.org/W1991211237","https://openalex.org/W1996864473","https://openalex.org/W1999347354","https://openalex.org/W2005970630","https://openalex.org/W2006862294","https://openalex.org/W2011921934","https://openalex.org/W2012264731","https://openalex.org/W2014608570","https://openalex.org/W2015823886","https://openalex.org/W2018853932","https://openalex.org/W2019082788","https://openalex.org/W2023731005","https://openalex.org/W2035821790","https://openalex.org/W2038288742","https://openalex.org/W2038569017","https://openalex.org/W2041475214","https://openalex.org/W2042077424","https://openalex.org/W2064109637","https://openalex.org/W2065021840","https://openalex.org/W2066805219","https://openalex.org/W2069907232","https://openalex.org/W2070966641","https://openalex.org/W2074234588","https://openalex.org/W2075703747","https://openalex.org/W2076363657","https://openalex.org/W2091396367","https://openalex.org/W2097143249","https://openalex.org/W2098059712","https://openalex.org/W2098238136","https://openalex.org/W2101099513","https://openalex.org/W2103183186","https://openalex.org/W2108121489","https://openalex.org/W2116844483","https://openalex.org/W2118559411","https://openalex.org/W2119609179","https://openalex.org/W2129261817","https://openalex.org/W2134604231","https://openalex.org/W2134987998","https://openalex.org/W2145185485","https://openalex.org/W2146347349","https://openalex.org/W2150313872","https://openalex.org/W2150345354","https://openalex.org/W2153336135","https://openalex.org/W2159632497","https://openalex.org/W2164471793","https://openalex.org/W2167903736","https://openalex.org/W2167923070","https://openalex.org/W2170088180","https://openalex.org/W2170401329","https://openalex.org/W2170715922","https://openalex.org/W2191706495","https://openalex.org/W2201485362","https://openalex.org/W2226586972","https://openalex.org/W2290487107","https://openalex.org/W2298351243","https://openalex.org/W2337535033","https://openalex.org/W2341244791","https://openalex.org/W2400164898","https://openalex.org/W2407467502","https://openalex.org/W2491282351","https://openalex.org/W2536477900","https://openalex.org/W2536936235","https://openalex.org/W2559954620","https://openalex.org/W2561832834","https://openalex.org/W2583929950","https://openalex.org/W2591879558","https://openalex.org/W2606711325","https://openalex.org/W2612993068","https://openalex.org/W2620406790","https://openalex.org/W2621944419","https://openalex.org/W2624616377","https://openalex.org/W2754669955","https://openalex.org/W2769668115","https://openalex.org/W2778495086","https://openalex.org/W2780977711","https://openalex.org/W2803031462","https://openalex.org/W2810324743","https://openalex.org/W2812742579","https://openalex.org/W2886865853","https://openalex.org/W2889235433","https://openalex.org/W2896299079","https://openalex.org/W2899203157","https://openalex.org/W2903177203","https://openalex.org/W2917520831","https://openalex.org/W2943483386","https://openalex.org/W2971036239","https://openalex.org/W2971515944","https://openalex.org/W2972783888","https://openalex.org/W2973077698"],"related_works":["https://openalex.org/W2166056344","https://openalex.org/W3182947552","https://openalex.org/W2588067799","https://openalex.org/W2505089096","https://openalex.org/W4400077346","https://openalex.org/W7095260458","https://openalex.org/W3180530455","https://openalex.org/W2767430590","https://openalex.org/W2762475907","https://openalex.org/W3009496837"],"abstract_inverted_index":{"Obesity":[0],"is":[1,10,59,67],"a":[2,31,72,133],"major":[3],"risk":[4,87,107],"factor":[5],"for":[6,12],"noncommunicable":[7],"diseases":[8],"that":[9,88,103],"responsible":[11],"more":[13,165],"than":[14],"70%":[15],"of":[16,85,100,124,154],"early":[17],"deaths":[18],"in":[19,108],"the":[20,23,98,122,129,152],"world.":[21],"In":[22,120],"1980's":[24],"decade,":[25],"some":[26,118],"studies":[27,146],"started":[28],"to":[29,75,139,149,159],"describe":[30],"\"benign\"":[32,64],"obesity":[33,42,65,77],"phenotype,":[34],"named":[35],"\"metabolically":[36],"healthy":[37],"obesity\"":[38],"(MHO),":[39],"which":[40],"represents":[41],"without":[43],"comorbidities":[44],"such":[45,111],"as":[46,112,132,156,158],"hypertension,":[47],"cardiovascular":[48,86,106,126,142],"diseases,":[49],"insulin":[50],"resistance,":[51],"diabetes,":[52],"dyslipidemia":[53],"or":[54,70],"metabolic":[55],"syndrome.":[56],"However,":[57],"it":[58],"still":[60],"unclear":[61],"if":[62,79],"this":[63],"phenotype":[66],"really":[68],"favorable":[69],"just":[71],"transition":[73],"status":[74],"unhealthy":[76],"and":[78,114],"these":[80,96],"subjects":[81],"presented":[82],"subclinical":[83,125],"levels":[84],"are":[89,147],"not":[90],"commonly":[91],"detected.":[92],"To":[93],"further":[94,145],"elucidate":[95],"issues,":[97],"investigation":[99],"pathophysiological":[101],"mechanisms":[102],"can":[104],"increase":[105],"MHO":[109,155],"individuals,":[110],"hormones":[113],"cytokines,":[115],"may":[116,135],"offer":[117],"responses.":[119],"parallel,":[121],"evaluation":[123],"derangement,":[127],"using":[128],"systemic":[130],"microcirculation":[131],"proxy,":[134],"be":[136],"an":[137],"alternative":[138],"anticipate":[140],"overt":[141],"disease.":[143],"Overall,":[144],"needed":[148],"better":[150],"understand":[151],"pathophysiology":[153],"well":[157],"identify":[160],"high-risk":[161],"individuals":[162],"who":[163],"deserve":[164],"intensive":[166],"management.":[167]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":7},{"year":2023,"cited_by_count":4},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":5}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2020-07-29T00:00:00"}
