{"id":"https://openalex.org/W3045108485","doi":null,"title":"Evaluation of Microbiome on Chicken Necrotic Enteritis and Growth Performance","display_name":"Evaluation of Microbiome on Chicken Necrotic Enteritis and Growth Performance","publication_year":2020,"publication_date":"2020-01-01","ids":{"openalex":"https://openalex.org/W3045108485","mag":"3045108485"},"language":"en","primary_location":{"id":"pmh:oai:scholarworks.uark.edu:etd-5199","doi":null,"is_oa":true,"landing_page_url":"https://scholarworks.uark.edu/etd/3634","pdf_url":"https://scholarworks.uark.edu/etd/3634","source":{"id":"https://openalex.org/S2764830181","display_name":"Journal of the Arkansas Academy of Science","issn_l":"2326-0491","issn":["2326-0491","2326-0505"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj"],"host_organization":"https://openalex.org/P4310320103","host_organization_name":"Arkansas Academy of Science","host_organization_lineage":["https://openalex.org/P4310320103"],"host_organization_lineage_names":["Arkansas Academy of Science"],"type":"journal"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Graduate Theses and Dissertations","raw_type":"text"},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://scholarworks.uark.edu/etd/3634","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5057603336","display_name":"Mussie Abraha","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Mussie Abraha","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5057603336"],"corresponding_institution_ids":[],"apc_list":{"value":300,"currency":"USD","value_usd":300},"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10152","display_name":"Animal Nutrition and Physiology","score":0.8622999787330627,"subfield":{"id":"https://openalex.org/subfields/1103","display_name":"Animal Science and Zoology"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10152","display_name":"Animal Nutrition and Physiology","score":0.8622999787330627,"subfield":{"id":"https://openalex.org/subfields/1103","display_name":"Animal Science and Zoology"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11288","display_name":"Clostridium difficile and Clostridium perfringens research","score":0.10419999808073044,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12691","display_name":"Coccidia and coccidiosis research","score":0.017000000923871994,"subfield":{"id":"https://openalex.org/subfields/1103","display_name":"Animal Science and Zoology"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/necrotic-enteritis","display_name":"necrotic enteritis","score":0.9800000190734863},{"id":"https://openalex.org/keywords/broiler-chickens","display_name":"broiler chickens","score":0.7590000033378601},{"id":"https://openalex.org/keywords/deoxycholic-acid","display_name":"deoxycholic acid","score":0.9819999933242798},{"id":"https://openalex.org/keywords/secondary-bile-acids","display_name":"secondary bile acids","score":0.9290000200271606},{"id":"https://openalex.org/keywords/gut-microbiota","display_name":"gut microbiota","score":0.8119999766349792},{"id":"https://openalex.org/keywords/eimeria-maxima","display_name":"Eimeria maxima","score":0.8109999895095825},{"id":"https://openalex.org/keywords/clostridium-perfringens","display_name":"Clostridium perfringens","score":1.0},{"id":"https://openalex.org/keywords/growth-performance","display_name":"growth performance","score":0.8209999799728394},{"id":"https://openalex.org/keywords/intestinal-histopathology","display_name":"intestinal histopathology","score":0.875},{"id":"https://openalex.org/keywords/inflammatory-gene-expression","display_name":"inflammatory gene expression","score":0.6990000009536743},{"id":"https://openalex.org/keywords/bile-acid-metabolomics","display_name":"bile acid metabolomics","score":0.5960000157356262},{"id":"https://openalex.org/keywords/probiotic-supplementation","display_name":"probiotic supplementation","score":0.39100000262260437},{"id":"https://openalex.org/keywords/drinking-water-supplementation","display_name":"drinking water supplementation","score":0.4189999997615814},{"id":"https://openalex.org/keywords/antimicrobial-alternatives","display_name":"antimicrobial alternatives","score":0.5350000262260437},{"id":"https://openalex.org/keywords/intestinal-inflammation","display_name":"intestinal inflammation","score":0.335999995470047},{"id":"https://openalex.org/keywords/cecal-microbiota","display_name":"cecal microbiota","score":0.38999998569488525}],"concepts":[{"id":"https://openalex.org/C143121216","wikidata":"https://www.wikidata.org/wiki/Q1330402","display_name":"Microbiome","level":2,"score":0.6877195239067078},{"id":"https://openalex.org/C2780031333","wikidata":"https://www.wikidata.org/wiki/Q854353","display_name":"Enteritis","level":2,"score":0.567973792552948},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4084846079349518},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3537771701812744},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.32232677936553955},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.2246459424495697}],"mesh":[],"locations_count":2,"locations":[{"id":"pmh:oai:scholarworks.uark.edu:etd-5199","doi":null,"is_oa":true,"landing_page_url":"https://scholarworks.uark.edu/etd/3634","pdf_url":"https://scholarworks.uark.edu/etd/3634","source":{"id":"https://openalex.org/S2764830181","display_name":"Journal of the Arkansas Academy of Science","issn_l":"2326-0491","issn":["2326-0491","2326-0505"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj"],"host_organization":"https://openalex.org/P4310320103","host_organization_name":"Arkansas Academy of Science","host_organization_lineage":["https://openalex.org/P4310320103"],"host_organization_lineage_names":["Arkansas Academy of Science"],"type":"journal"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Graduate Theses and Dissertations","raw_type":"text"},{"id":"mag:3045108485","doi":null,"is_oa":false,"landing_page_url":"https://scholarworks.uark.edu/etd/3634/","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"pmh:oai:scholarworks.uark.edu:etd-5199","doi":null,"is_oa":true,"landing_page_url":"https://scholarworks.uark.edu/etd/3634","pdf_url":"https://scholarworks.uark.edu/etd/3634","source":{"id":"https://openalex.org/S2764830181","display_name":"Journal of the Arkansas Academy of Science","issn_l":"2326-0491","issn":["2326-0491","2326-0505"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj"],"host_organization":"https://openalex.org/P4310320103","host_organization_name":"Arkansas Academy of Science","host_organization_lineage":["https://openalex.org/P4310320103"],"host_organization_lineage_names":["Arkansas Academy of Science"],"type":"journal"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Graduate Theses and Dissertations","raw_type":"text"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9391000270843506,"display_name":"Good health and well-being"},{"id":"https://metadata.un.org/sdg/2","score":0.8409000039100647,"display_name":"Zero hunger"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3045108485.pdf","grobid_xml":"https://content.openalex.org/works/W3045108485.grobid-xml"},"referenced_works_count":122,"referenced_works":["https://openalex.org/W958079127","https://openalex.org/W1595756852","https://openalex.org/W1596959401","https://openalex.org/W1599065434","https://openalex.org/W1965796890","https://openalex.org/W1967039153","https://openalex.org/W1968684496","https://openalex.org/W1974556168","https://openalex.org/W1974993651","https://openalex.org/W1976374362","https://openalex.org/W1977328678","https://openalex.org/W1977712542","https://openalex.org/W1978002793","https://openalex.org/W1979012796","https://openalex.org/W1981341928","https://openalex.org/W1984345984","https://openalex.org/W1985419386","https://openalex.org/W1990363562","https://openalex.org/W1990619325","https://openalex.org/W1991414612","https://openalex.org/W1993830991","https://openalex.org/W1997103274","https://openalex.org/W1999323594","https://openalex.org/W2004444336","https://openalex.org/W2005320735","https://openalex.org/W2006608615","https://openalex.org/W2009437244","https://openalex.org/W2012606594","https://openalex.org/W2014965759","https://openalex.org/W2018274907","https://openalex.org/W2019503994","https://openalex.org/W2021206718","https://openalex.org/W2022279737","https://openalex.org/W2022972067","https://openalex.org/W2023867397","https://openalex.org/W2026462493","https://openalex.org/W2031686588","https://openalex.org/W2032812017","https://openalex.org/W2034020543","https://openalex.org/W2034965138","https://openalex.org/W2035779227","https://openalex.org/W2036495967","https://openalex.org/W2043126697","https://openalex.org/W2047602826","https://openalex.org/W2050949396","https://openalex.org/W2051656062","https://openalex.org/W2052543334","https://openalex.org/W2052638070","https://openalex.org/W2053581007","https://openalex.org/W2056525511","https://openalex.org/W2056941041","https://openalex.org/W2060287557","https://openalex.org/W2065051999","https://openalex.org/W2070180494","https://openalex.org/W2071273298","https://openalex.org/W2078810890","https://openalex.org/W2081157135","https://openalex.org/W2081991584","https://openalex.org/W2084299481","https://openalex.org/W2084990558","https://openalex.org/W2086262827","https://openalex.org/W2088781465","https://openalex.org/W2093472955","https://openalex.org/W2096029332","https://openalex.org/W2097297514","https://openalex.org/W2098167705","https://openalex.org/W2099266276","https://openalex.org/W2099963897","https://openalex.org/W2100706861","https://openalex.org/W2101558615","https://openalex.org/W2103101831","https://openalex.org/W2108038274","https://openalex.org/W2110936821","https://openalex.org/W2111107884","https://openalex.org/W2112463223","https://openalex.org/W2114793991","https://openalex.org/W2116205144","https://openalex.org/W2122674349","https://openalex.org/W2123561714","https://openalex.org/W2124971916","https://openalex.org/W2126979693","https://openalex.org/W2127850606","https://openalex.org/W2128705098","https://openalex.org/W2129362189","https://openalex.org/W2134897177","https://openalex.org/W2137448333","https://openalex.org/W2140184866","https://openalex.org/W2141145871","https://openalex.org/W2141179660","https://openalex.org/W2142023354","https://openalex.org/W2142440912","https://openalex.org/W2142796099","https://openalex.org/W2143358720","https://openalex.org/W2145130662","https://openalex.org/W2146755217","https://openalex.org/W2147259528","https://openalex.org/W2147748030","https://openalex.org/W2148908418","https://openalex.org/W2152653674","https://openalex.org/W2152830637","https://openalex.org/W2154556265","https://openalex.org/W2155378208","https://openalex.org/W2156618827","https://openalex.org/W2162904770","https://openalex.org/W2163183582","https://openalex.org/W2163628831","https://openalex.org/W2171605634","https://openalex.org/W2246162222","https://openalex.org/W2316224242","https://openalex.org/W2321981887","https://openalex.org/W2322361714","https://openalex.org/W2322567605","https://openalex.org/W2324603445","https://openalex.org/W2331088109","https://openalex.org/W2407259822","https://openalex.org/W2479689167","https://openalex.org/W2558943513","https://openalex.org/W2789685640","https://openalex.org/W2796250849","https://openalex.org/W2901559061","https://openalex.org/W2938282721","https://openalex.org/W3001290322"],"related_works":["https://openalex.org/W3143587034","https://openalex.org/W3012645156","https://openalex.org/W2794057268","https://openalex.org/W3194137441","https://openalex.org/W4412456332","https://openalex.org/W2887999972","https://openalex.org/W2942127833","https://openalex.org/W4405651669","https://openalex.org/W4288447965","https://openalex.org/W323828255"],"abstract_inverted_index":{"Necrotic":[0],"enteritis":[1],"(NE)":[2],"has":[3],"re-emerged":[4],"following":[5],"restriction":[6],"of":[7,20,29,152,192,214,225,238,249,259,266,494],"antimicrobial":[8,476],"usage":[9],"and":[10,27,49,57,70,76,78,97,103,105,126,132,174,185,199,293,299,308,337,340,413,418,457,496,501],"costs":[11],"$6":[12],"billion":[13],"every":[14],"year":[15],"worldwide.":[16],"The":[17,256,314],"primary":[18],"objective":[19,258],"the":[21,59,79,168,260],"studies":[22,261],"was":[23,111,208,245,262,280,331,346],"to":[24,203,263,311,371,385,401,428,479,492],"evaluate":[25],"prevention":[26,500],"treatment":[28],"NE":[30,144,155,200,244,499],"using":[31,138,348],"a":[32],"microbiota":[33,470,497],"metabolic":[34,447],"product,":[35],"secondary":[36],"bile":[37,239,251,466],"acid":[38,40,467],"deoxycholic":[39],"(DCA),":[41],"in":[42,51,113,146,157,171,182,188,197,218,231,253,450],"drinking":[43,114,451],"water.":[44],"Day-old":[45,303],"birds":[46,60,80,89,145,156,201,304,315,375,387,397,403,415,430],"were":[47,61,81,90,128,136,305,316],"tagged":[48],"placed":[50],"floor":[52],"pens.":[53,313],"In":[54,86,444],"experiments":[55,172,183],"1":[56,148,173,184],"2,":[58],"infected":[62,91],"with":[63,92,247,320,356,377],"Eimeria":[64,93],"maxima":[65],"(Em)":[66],"at":[67,73,83,94,100,107,116,164,333,342],"d":[68,74,84,95,101,108,334,338,343,362],"18":[69],"C.":[71,98,227,462],"perfringens":[72,99,228,463],"23":[75],"24":[77,366,390],"euthanized":[82,106,341],"26.":[85],"experiment":[87,147,158,189,219,232],"3,":[88],"20":[96],"25":[102],"26":[104],"27.":[109],"DCA":[110,163,210,222,449,495],"administered":[112],"water":[115,452],"1.91,":[117],"0.95,":[118],"or":[119,290,325],"0.48":[120],"mM,":[121],"respectively.":[122],"Small":[123],"intestinal":[124,180],"content":[125],"tissue":[127,207],"collected":[129,294],"for":[130,498],"histopathology":[131,181],"molecular":[133],"study.":[134],"Data":[135,345],"analyzed":[137,347],"one-way":[139,349],"ANOVA":[140,350],"followed":[141,351],"by":[142,352],"t-test.":[143,353],"developed":[149],"subclinical":[150],"signs":[151],"NE,":[153],"while":[154,374],"3":[159],"suffered":[160],"acute":[161],"NE.":[162],"1.91":[165],"mM":[166],"attenuated":[167],"BWG":[169,455],"loss":[170],"3.":[175,186],"Consistently,":[176,395],"it":[177],"reduced":[178,211,223],"NE-induced":[179,212,454],"However,":[187],"2":[190],"because":[191],"minimal":[193],"body":[194,382,424,482],"weight":[195,330,383,425,483],"alteration":[196],"Em":[198],"compared":[202,370,384,400,427],"non-infected":[204],"birds,":[205,373],"no":[206],"collected.":[209],"expression":[213],"inflammatory":[215],"gene":[216],"Inf\u03b3":[217],"1.":[220,233],"Similarly,":[221],"elevation":[224],"NE-associated":[226],"luminal":[229],"colonization":[230,464],"Using":[234],"targeted":[235],"metabolomics":[236],"(LC-MS/MS)":[237],"acids,":[240],"we":[241],"found":[242],"that":[243],"associated":[246],"reduction":[248,456],"total":[250],"acids":[252],"ileal":[254],"content.":[255],"second":[257],"examine":[264],"improvement":[265],"broiler":[267],"chickens":[268],"growth":[269,502],"through":[270,460],"modulating":[271],"gut":[272],"microbiota.":[273,302],"Mouse":[274],"specific":[275],"pathogen":[276],"free":[277,477],"(SPF)":[278],"stool":[279],"cultured":[281],"on":[282,422],"Brain":[283],"Heart":[284],"Infusion":[285],"(BHI)":[286],"agar":[287],"under":[288],"anaerobic":[289,297],"aerobic":[291,300],"condition":[292],"as":[295,474],"SPF":[296],"(SPF-Anaero)":[298],"(SPF-Aero)":[301],"tagged,":[306],"weighed":[307],"randomly":[309],"assigned":[310],"9":[312],"then":[317],"orally":[318],"gavaged":[319],"PBS,":[321],"108":[322,326],"CFU/bird":[323,327],"SPF-Anaero,":[324],"SPF-Aero.":[328],"Body":[329],"measured":[332],"0,":[335],"14,":[336],"28,":[339],"28.":[344],"Birds":[354],"colonized":[355,376],"SPF-Anaero":[357,396,412],"grew":[358,398,416],"15%":[359],"heavier":[360,421],"during":[361,404],"0-14":[363],"(28":[364],"vs.":[365,389,407,432,438],"g/day/bird,":[367,409,434,440],"P=":[368,393,410,435,441],"0.0009)":[369],"control":[372,386,402,429],"SPF-Aero":[378,414],"gained":[379],"8%":[380],"more":[381],"(26":[388],"g/day":[391],"/bird,":[392],"0.02).":[394],"faster":[399],"d14-28":[405],"(67":[406],"60":[408],"0.007).":[411],"15":[417],"4%,":[419],"respectively,":[420],"accumulative":[423],"gain":[426],"(47":[431],"42":[433,439],"0.0009;":[436],"44":[437],"0.03,":[442],"respectively).":[443],"conclusion,":[445],"microbial":[446],"product":[448],"prevents":[453],"histopathology,":[458],"perhaps":[459],"reducing":[461],"and/or":[465],"restoration.":[468],"Modulating":[469],"could":[471],"be":[472],"used":[473],"an":[475,489],"alternative":[478,490],"improve":[480],"bird":[481],"gain.":[484],"These":[485],"findings":[486],"may":[487],"offer":[488],"strategy":[491],"use":[493],"promotion.":[503]},"counts_by_year":[],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2020-07-29T00:00:00"}