{"id":"https://openalex.org/W3043844338","doi":"https://doi.org/10.1080/25785826.2020.1794165","title":"Immunoinformatics design of multiepitopes peptide-based universal cancer vaccine using matrix metalloproteinase-9 protein as a target","display_name":"Immunoinformatics design of multiepitopes peptide-based universal cancer vaccine using matrix metalloproteinase-9 protein as a target","publication_year":2020,"publication_date":"2020-07-21","ids":{"openalex":"https://openalex.org/W3043844338","doi":"https://doi.org/10.1080/25785826.2020.1794165","mag":"3043844338","pmid":"https://pubmed.ncbi.nlm.nih.gov/32692610"},"language":"en","primary_location":{"id":"doi:10.1080/25785826.2020.1794165","doi":"https://doi.org/10.1080/25785826.2020.1794165","is_oa":true,"landing_page_url":"https://doi.org/10.1080/25785826.2020.1794165","pdf_url":null,"source":{"id":"https://openalex.org/S4306551435","display_name":"Immunological Medicine","issn_l":"2578-5826","issn":["2578-5826"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["doaj","dongbi-d","medline","oarl","poland-20","russia-white-list-2"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Immunological Medicine","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://doi.org/10.1080/25785826.2020.1794165","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5036799348","display_name":"Abdelrahman Hamza Abdelmoneim","orcid":"https://orcid.org/0000-0002-5037-8488","observed_orcids":["https://orcid.org/0000-0002-5037-8488"]},"institutions":[{"id":"https://openalex.org/I224517680","display_name":"Al-Neelain University","ror":"https://ror.org/05dvsnx49","country_code":"SD","type":"education","lineage":["https://openalex.org/I224517680"]}],"countries":["SD"],"is_corresponding":true,"raw_author_name":"Abdelrahman H. Abdelmoneim","raw_affiliation_strings":["Faculty of Medicine, Al-Neelain University","Faculty of Medicine, Al-Neelain University, Khartoum, Sudan"],"raw_orcid":"https://orcid.org/0000-0002-5037-8488","affiliations":[{"raw_affiliation_string":"Faculty of Medicine, Al-Neelain University","institution_ids":["https://openalex.org/I224517680"]},{"raw_affiliation_string":"Faculty of Medicine, Al-Neelain University, Khartoum, Sudan","institution_ids":["https://openalex.org/I224517680"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069282067","display_name":"Mujahed I. Mustafa","orcid":"https://orcid.org/0000-0001-6893-0536","observed_orcids":["https://orcid.org/0000-0001-6893-0536"]},"institutions":[{"id":"https://openalex.org/I4210148209","display_name":"University of Bahri","ror":"https://ror.org/05jds5x60","country_code":"SD","type":"education","lineage":["https://openalex.org/I4210148209"]}],"countries":["SD"],"is_corresponding":false,"raw_author_name":"Mujahed I. Mustafa","raw_affiliation_strings":["Department of Biotechnology, University of Bahri","Department of Biotechnology, University of Bahri, Khartoum, Sudan"],"raw_orcid":"https://orcid.org/0000-0001-6893-0536","affiliations":[{"raw_affiliation_string":"Department of Biotechnology, University of Bahri","institution_ids":["https://openalex.org/I4210148209"]},{"raw_affiliation_string":"Department of Biotechnology, University of Bahri, Khartoum, Sudan","institution_ids":["https://openalex.org/I4210148209"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069268842","display_name":"Miyssa I. Abdelmageed","orcid":"https://orcid.org/0000-0002-7655-1592","observed_orcids":["https://orcid.org/0000-0002-7655-1592"]},"institutions":[{"id":"https://openalex.org/I150406212","display_name":"University of Khartoum","ror":"https://ror.org/02jbayz55","country_code":"SD","type":"education","lineage":["https://openalex.org/I150406212"]}],"countries":["SD"],"is_corresponding":false,"raw_author_name":"Miyssa I. Abdelmageed","raw_affiliation_strings":["Faculty of Pharmacy, University of Khartoum","Faculty of Pharmacy, University of Khartoum, Khartoum, Sudan"],"raw_orcid":"https://orcid.org/0000-0002-7655-1592","affiliations":[{"raw_affiliation_string":"Faculty of Pharmacy, University of Khartoum","institution_ids":["https://openalex.org/I150406212"]},{"raw_affiliation_string":"Faculty of Pharmacy, University of Khartoum, Khartoum, Sudan","institution_ids":["https://openalex.org/I150406212"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086625927","display_name":"Naseem S. Murshed","orcid":"https://orcid.org/0000-0003-2884-2528","observed_orcids":["https://orcid.org/0000-0003-2884-2528"]},"institutions":[{"id":"https://openalex.org/I263913023","display_name":"International University of Africa","ror":"https://ror.org/029jt9a82","country_code":"SD","type":"education","lineage":["https://openalex.org/I263913023"]}],"countries":["SD"],"is_corresponding":false,"raw_author_name":"Naseem S. Murshed","raw_affiliation_strings":["Department of Microbiology, International University of Africa","Department of Microbiology, International University of Africa, Khartoum, Sudan"],"raw_orcid":"https://orcid.org/0000-0003-2884-2528","affiliations":[{"raw_affiliation_string":"Department of Microbiology, International University of Africa","institution_ids":["https://openalex.org/I263913023"]},{"raw_affiliation_string":"Department of Microbiology, International University of Africa, Khartoum, Sudan","institution_ids":["https://openalex.org/I263913023"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019284871","display_name":"Enas dk. Dawoud","orcid":"https://orcid.org/0000-0001-5439-930X","observed_orcids":["https://orcid.org/0000-0001-5439-930X"]},"institutions":[{"id":"https://openalex.org/I1187138","display_name":"Razi University","ror":"https://ror.org/02ynb0474","country_code":"IR","type":"education","lineage":["https://openalex.org/I1187138"]}],"countries":["IR"],"is_corresponding":false,"raw_author_name":"Enas dk. Dawoud","raw_affiliation_strings":["Faculty of Medical laboratory sciences, Razi University","Faculty of Medical laboratory sciences, Razi University, Khartoum, Sudan"],"raw_orcid":"https://orcid.org/0000-0001-5439-930X","affiliations":[{"raw_affiliation_string":"Faculty of Medical laboratory sciences, Razi University","institution_ids":["https://openalex.org/I1187138"]},{"raw_affiliation_string":"Faculty of Medical laboratory sciences, Razi University, Khartoum, Sudan","institution_ids":[]}]},{"author_position":"middle","author":{"id":null,"display_name":"Enas M. Ahmed","orcid":"https://orcid.org/0000-0002-8252-6529","observed_orcids":["https://orcid.org/0000-0002-8252-6529"]},"institutions":[{"id":"https://openalex.org/I64838667","display_name":"Karary University","ror":"https://ror.org/03ws81249","country_code":"SD","type":"education","lineage":["https://openalex.org/I64838667"]}],"countries":["SD"],"is_corresponding":false,"raw_author_name":"Enas M. Ahmed","raw_affiliation_strings":["Faculty of Medicine, Karary University","Faculty of Medicine, Karary University, Khartoum, Sudan"],"raw_orcid":"https://orcid.org/0000-0002-8252-6529","affiliations":[{"raw_affiliation_string":"Faculty of Medicine, Karary University","institution_ids":["https://openalex.org/I64838667"]},{"raw_affiliation_string":"Faculty of Medicine, Karary University, Khartoum, Sudan","institution_ids":["https://openalex.org/I64838667"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003172901","display_name":"Rahma M. Kamal Eldein","orcid":"https://orcid.org/0000-0003-4726-1710","observed_orcids":["https://orcid.org/0000-0003-4726-1710"]},"institutions":[{"id":"https://openalex.org/I64838667","display_name":"Karary University","ror":"https://ror.org/03ws81249","country_code":"SD","type":"education","lineage":["https://openalex.org/I64838667"]}],"countries":["SD"],"is_corresponding":false,"raw_author_name":"Rahma M. Kamal Eldein","raw_affiliation_strings":["Faculty of Oral and Dental medicine, Karary University","Faculty of Oral and Dental medicine, Karary University, Khartoum, Sudan"],"raw_orcid":"https://orcid.org/0000-0003-4726-1710","affiliations":[{"raw_affiliation_string":"Faculty of Oral and Dental medicine, Karary University","institution_ids":["https://openalex.org/I64838667"]},{"raw_affiliation_string":"Faculty of Oral and Dental medicine, Karary University, Khartoum, Sudan","institution_ids":["https://openalex.org/I64838667"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034137860","display_name":"Nafisa M. Elfadol","orcid":"https://orcid.org/0000-0003-2886-2043","observed_orcids":["https://orcid.org/0000-0003-2886-2043"]},"institutions":[{"id":"https://openalex.org/I4405266400","display_name":"National University Biomedical Research Institute","ror":"https://ror.org/02p1t2117","country_code":"SD","type":"facility","lineage":["https://openalex.org/I4405266400"]}],"countries":["SD"],"is_corresponding":false,"raw_author_name":"Nafisa M. Elfadol","raw_affiliation_strings":["National University Biomedical Research Institute, National University","National University Biomedical Research Institute, National University, Khartoum, Sudan"],"raw_orcid":"https://orcid.org/0000-0003-2886-2043","affiliations":[{"raw_affiliation_string":"National University Biomedical Research Institute, National University","institution_ids":["https://openalex.org/I4405266400"]},{"raw_affiliation_string":"National University Biomedical Research Institute, National University, Khartoum, Sudan","institution_ids":["https://openalex.org/I4405266400"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037449656","display_name":"Anfal Osama Mohamed Sati","orcid":"https://orcid.org/0000-0002-0589-2306","observed_orcids":["https://orcid.org/0000-0002-0589-2306"]},"institutions":[{"id":"https://openalex.org/I1187138","display_name":"Razi University","ror":"https://ror.org/02ynb0474","country_code":"IR","type":"education","lineage":["https://openalex.org/I1187138"]}],"countries":["IR"],"is_corresponding":false,"raw_author_name":"Anfal Osama M. Sati","raw_affiliation_strings":["Faculty of Medical laboratory sciences, Razi University","Faculty of Medical laboratory sciences, Razi University, Khartoum, Sudan"],"raw_orcid":"https://orcid.org/0000-0002-0589-2306","affiliations":[{"raw_affiliation_string":"Faculty of Medical laboratory sciences, Razi University","institution_ids":["https://openalex.org/I1187138"]},{"raw_affiliation_string":"Faculty of Medical laboratory sciences, Razi University, Khartoum, Sudan","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5041712116","display_name":"Abdelrafie Mohamed Makhawi","orcid":"https://orcid.org/0000-0002-7498-6242","observed_orcids":["https://orcid.org/0000-0002-7498-6242"]},"institutions":[{"id":"https://openalex.org/I4210148209","display_name":"University of Bahri","ror":"https://ror.org/05jds5x60","country_code":"SD","type":"education","lineage":["https://openalex.org/I4210148209"]}],"countries":["SD"],"is_corresponding":false,"raw_author_name":"Abdelrafie M. Makhawi","raw_affiliation_strings":["Department of Biotechnology, University of Bahri","Department of Biotechnology, University of Bahri, Khartoum, Sudan"],"raw_orcid":"https://orcid.org/0000-0002-7498-6242","affiliations":[{"raw_affiliation_string":"Department of Biotechnology, University of Bahri","institution_ids":["https://openalex.org/I4210148209"]},{"raw_affiliation_string":"Department of Biotechnology, University of Bahri, Khartoum, Sudan","institution_ids":["https://openalex.org/I4210148209"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":7,"corresponding_author_ids":["https://openalex.org/A5036799348"],"corresponding_institution_ids":["https://openalex.org/I224517680"],"apc_list":null,"apc_paid":null,"fwci":1.072,"has_fulltext":false,"cited_by_count":17,"citation_normalized_percentile":{"value":0.74052015,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":98},"biblio":{"volume":"44","issue":"1","first_page":"35","last_page":"52"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12576","display_name":"vaccines and immunoinformatics approaches","score":0.9955999851226807,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12576","display_name":"vaccines and immunoinformatics approaches","score":0.9955999851226807,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10580","display_name":"Immunotherapy and Immune Responses","score":0.003700000001117587,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10911","display_name":"Chemical Synthesis and Analysis","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/mmp-9","display_name":"MMP-9","score":0.9100000262260437},{"id":"https://openalex.org/keywords/immunoinformatics","display_name":"immunoinformatics","score":0.7319999933242798},{"id":"https://openalex.org/keywords/mhc-class-i-epitopes","display_name":"MHC class I epitopes","score":0.7799999713897705},{"id":"https://openalex.org/keywords/mhc-class-ii-epitopes","display_name":"MHC class II epitopes","score":1.0},{"id":"https://openalex.org/keywords/b-cell-epitopes","display_name":"B-cell epitopes","score":0.9100000262260437},{"id":"https://openalex.org/keywords/t-cell-epitopes","display_name":"T cell epitopes","score":0.9440000057220459},{"id":"https://openalex.org/keywords/population-coverage","display_name":"population coverage","score":0.5559999942779541},{"id":"https://openalex.org/keywords/metastasis","display_name":"metastasis","score":0.5809999704360962},{"id":"https://openalex.org/keywords/peptide-peptide-interactions","display_name":"peptide-peptide interactions","score":0.4519999921321869}],"concepts":[{"id":"https://openalex.org/C2775997469","wikidata":"https://www.wikidata.org/wiki/Q18029196","display_name":"MMP9","level":4,"score":0.5260229706764221},{"id":"https://openalex.org/C2779281246","wikidata":"https://www.wikidata.org/wiki/Q172847","display_name":"Peptide","level":2,"score":0.48065245151519775},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.47427353262901306},{"id":"https://openalex.org/C2776789287","wikidata":"https://www.wikidata.org/wiki/Q7166532","display_name":"Peptide vaccine","level":4,"score":0.45181941986083984},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.4474136233329773},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.4288775324821472},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.4201996922492981},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.3291773200035095},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.31958675384521484},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.30195873975753784},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.2943195700645447},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.2611846327781677},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.1782068908214569},{"id":"https://openalex.org/C127561419","wikidata":"https://www.wikidata.org/wiki/Q224527","display_name":"Downregulation and upregulation","level":3,"score":0.12923866510391235},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.11792552471160889},{"id":"https://openalex.org/C195616568","wikidata":"https://www.wikidata.org/wiki/Q128711","display_name":"Epitope","level":3,"score":0.08120492100715637},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000949","descriptor_name":"Histocompatibility Antigens Class II","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001402","descriptor_name":"B-Lymphocytes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011485","descriptor_name":"Protein Binding","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015195","descriptor_name":"Drug Design","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015395","descriptor_name":"Histocompatibility Antigens Class I","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018984","descriptor_name":"Epitopes, T-Lymphocyte","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018985","descriptor_name":"Epitopes, B-Lymphocyte","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019496","descriptor_name":"Cancer Vaccines","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D020780","descriptor_name":"Matrix Metalloproteinase 9","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D022223","descriptor_name":"Vaccines, Subunit","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D062105","descriptor_name":"Molecular Docking Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1080/25785826.2020.1794165","doi":"https://doi.org/10.1080/25785826.2020.1794165","is_oa":true,"landing_page_url":"https://doi.org/10.1080/25785826.2020.1794165","pdf_url":null,"source":{"id":"https://openalex.org/S4306551435","display_name":"Immunological Medicine","issn_l":"2578-5826","issn":["2578-5826"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["doaj","dongbi-d","medline","oarl","poland-20","russia-white-list-2"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Immunological Medicine","raw_type":"journal-article"},{"id":"doi:10.1101/2020.02.16.951319","doi":"https://doi.org/10.1101/2020.02.16.951319","is_oa":true,"landing_page_url":"https://doi.org/10.1101/2020.02.16.951319","pdf_url":"https://www.biorxiv.org/content/biorxiv/early/2020/02/25/2020.02.16.951319.full.pdf","source":{"id":"https://openalex.org/S4306402567","display_name":"bioRxiv (Cold Spring Harbor Laboratory)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2750212522","host_organization_name":"Cold Spring Harbor Laboratory","host_organization_lineage":["https://openalex.org/I2750212522"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"bioRxiv","raw_type":"posted-content"},{"id":"pmid:32692610","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/32692610","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Immunological medicine","raw_type":"Journal Article"},{"id":"pmh:oai:doaj.org/article:bbd12e4432ed4d94a99a62b4c46d4ee3","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/bbd12e4432ed4d94a99a62b4c46d4ee3","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Immunological Medicine, Vol 44, Iss 1, Pp 35-52 (2021)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1080/25785826.2020.1794165","doi":"https://doi.org/10.1080/25785826.2020.1794165","is_oa":true,"landing_page_url":"https://doi.org/10.1080/25785826.2020.1794165","pdf_url":null,"source":{"id":"https://openalex.org/S4306551435","display_name":"Immunological Medicine","issn_l":"2578-5826","issn":["2578-5826"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["doaj","dongbi-d","medline","oarl","poland-20","russia-white-list-2"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Immunological Medicine","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.98580002784729,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3043844338.pdf","grobid_xml":"https://content.openalex.org/works/W3043844338.grobid-xml"},"referenced_works_count":83,"referenced_works":["https://openalex.org/W1230369233","https://openalex.org/W1503364994","https://openalex.org/W1526839960","https://openalex.org/W1686700912","https://openalex.org/W1781429089","https://openalex.org/W1826514729","https://openalex.org/W1832355851","https://openalex.org/W1981106544","https://openalex.org/W1988789252","https://openalex.org/W2015176909","https://openalex.org/W2035240910","https://openalex.org/W2048233935","https://openalex.org/W2062173928","https://openalex.org/W2066609648","https://openalex.org/W2096477330","https://openalex.org/W2098918131","https://openalex.org/W2100350770","https://openalex.org/W2101746842","https://openalex.org/W2102367710","https://openalex.org/W2105668062","https://openalex.org/W2110574412","https://openalex.org/W2122779464","https://openalex.org/W2125732073","https://openalex.org/W2127635589","https://openalex.org/W2127814614","https://openalex.org/W2131758778","https://openalex.org/W2132286877","https://openalex.org/W2132629607","https://openalex.org/W2134967712","https://openalex.org/W2139173457","https://openalex.org/W2142447995","https://openalex.org/W2143397050","https://openalex.org/W2155020307","https://openalex.org/W2160397907","https://openalex.org/W2169961966","https://openalex.org/W2171295581","https://openalex.org/W2173732482","https://openalex.org/W2336794604","https://openalex.org/W2342838938","https://openalex.org/W2438592214","https://openalex.org/W2468420207","https://openalex.org/W2490219786","https://openalex.org/W2594071156","https://openalex.org/W2599717252","https://openalex.org/W2606784110","https://openalex.org/W2611314002","https://openalex.org/W2620457065","https://openalex.org/W2742617701","https://openalex.org/W2754516505","https://openalex.org/W2778441553","https://openalex.org/W2787553551","https://openalex.org/W2794259554","https://openalex.org/W2795352016","https://openalex.org/W2799710201","https://openalex.org/W2800760767","https://openalex.org/W2801082810","https://openalex.org/W2802731336","https://openalex.org/W2889646458","https://openalex.org/W2890854864","https://openalex.org/W2891317528","https://openalex.org/W2894279258","https://openalex.org/W2896976884","https://openalex.org/W2900960361","https://openalex.org/W2902376262","https://openalex.org/W2906628163","https://openalex.org/W2910310094","https://openalex.org/W2911188335","https://openalex.org/W2938054231","https://openalex.org/W2948660510","https://openalex.org/W2951071083","https://openalex.org/W2955578920","https://openalex.org/W2964457955","https://openalex.org/W2964771624","https://openalex.org/W2965472743","https://openalex.org/W2966096763","https://openalex.org/W2971050087","https://openalex.org/W2972594981","https://openalex.org/W2979558832","https://openalex.org/W2987497707","https://openalex.org/W2992783510","https://openalex.org/W2999417355","https://openalex.org/W3022974266","https://openalex.org/W4252183523"],"related_works":["https://openalex.org/W4389647550","https://openalex.org/W4297934705","https://openalex.org/W2486358486","https://openalex.org/W3089055161","https://openalex.org/W2511078803","https://openalex.org/W7164509858","https://openalex.org/W2062538030","https://openalex.org/W4283645597","https://openalex.org/W4303986656","https://openalex.org/W2013308940"],"abstract_inverted_index":{"A":[0],"new":[1],"approach":[2],"toward":[3],"cancer":[4,10,56,186],"therapy":[5],"is":[6,37],"the":[7,13,20,42,71,80,146,156,164,167,171],"use":[8,31,182],"of":[9,17,22,46,49,62,140,166,173],"vaccine,":[11],"yet":[12],"different":[14],"molecular":[15,151],"bases":[16],"cancers,":[18],"reduce":[19],"effectiveness":[21,165],"this":[23,26,174],"approach.":[24],"In":[25],"article,":[27],"we":[28],"aim":[29],"to":[30,102,162],"matrix":[32],"metalloproteinase-9":[33],"protein":[34,64],"(MMP9)":[35],"which":[36,188],"an":[38],"essential":[39],"molecule":[40],"in":[41],"survival":[43],"and":[44,73,83,113,127,142,150,159,198],"metastasis":[45],"all":[47],"types":[48],"cancers":[50],"as":[51,120,183],"a":[52,184,190],"target":[53],"for":[54,106,123,133,181,195],"universal":[55,185],"vaccine":[57,178,187],"design.":[58],"The":[59,88],"reference":[60],"sequence":[61],"MMP9":[63],"was":[65,179],"obtained":[66],"from":[67],"NCBI":[68],"databases.":[69],"Furthermore,":[70],"B-cell":[72],"T":[74],"cell-related":[75],"peptides":[76,91,99,117,130],"were":[77,92,100,118,153],"analyzed":[78],"using":[79,95,155],"IEDB":[81],"website":[82],"other":[84],"related":[85,201],"soft":[86],"wares.":[87],"best":[89],"candidate":[90],"then":[93],"visualized":[94],"chimera":[96],"software.":[97],"Three":[98],"found":[101,119],"be":[103],"good":[104,121],"candidates":[105],"interactions":[107,124,134],"with":[108,125,135,137],"B":[109],"cells":[110],"(SLPE,":[111],"RLYT,":[112],"PALPR),":[114],"while":[115],"10":[116,129],"targets":[122],"MHC1":[126,196],"another":[128],"founded":[131],"suitable":[132],"MHC2":[136,199],"population":[138,193],"coverages":[139],"94.77":[141],"90.67%,":[143],"respectively.":[144],"Finally,":[145],"immune":[147],"response":[148],"simulation":[149],"docking":[152],"done":[154],"C-IMMSIM":[157],"simulator":[158],"AutoDock":[160],"Vina":[161],"confirm":[163],"proposed":[168],"vaccine.":[169],"By":[170],"end":[172],"project:":[175],"twenty-three":[176],"peptide-based":[177],"designed":[180],"has":[189],"high":[191],"world":[192],"coverage":[194],"(94.77%)":[197],"(90.67%)":[200],"alleles.":[202]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":1},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":6},{"year":2021,"cited_by_count":4},{"year":2020,"cited_by_count":2}],"updated_date":"2026-11-09T13:22:03.289127","created_date":"2020-07-29T00:00:00"}