{"id":"https://openalex.org/W3042897403","doi":"https://doi.org/10.4250/jcvi.2020.0038","title":"An Analysis of Myocardial Efficiency in Patients with Severe Asymptomatic Mitral Regurgitation","display_name":"An Analysis of Myocardial Efficiency in Patients with Severe Asymptomatic Mitral Regurgitation","publication_year":2020,"publication_date":"2020-01-01","ids":{"openalex":"https://openalex.org/W3042897403","doi":"https://doi.org/10.4250/jcvi.2020.0038","mag":"3042897403","pmid":"https://pubmed.ncbi.nlm.nih.gov/33086443","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/7572264"},"language":"en","primary_location":{"id":"doi:10.4250/jcvi.2020.0038","doi":"https://doi.org/10.4250/jcvi.2020.0038","is_oa":true,"landing_page_url":"https://doi.org/10.4250/jcvi.2020.0038","pdf_url":null,"source":{"id":"https://openalex.org/S4394735500","display_name":"Journal of Cardiovascular Imaging","issn_l":"2586-7296","issn":["2586-7296","2586-7210"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","kci-registered","ki-jl-1","poland-20","russia-white-list-2"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Cardiovascular Imaging","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://doi.org/10.4250/jcvi.2020.0038","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5003591811","display_name":"Rengin \u00c7etin G\u00fcven\u00e7","orcid":"https://orcid.org/0000-0002-9579-5509","observed_orcids":["https://orcid.org/0000-0002-9579-5509"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Rengin \u00c7etin G\u00fcven\u00e7","raw_affiliation_strings":["Division of Cardiology, Dr. Siyami Ersek Cardiovascular and Thoracic Surgery Research and Training Hospital, Istanbul, Turkey"],"raw_orcid":"https://orcid.org/0000-0002-9579-5509","affiliations":[{"raw_affiliation_string":"Division of Cardiology, Dr. Siyami Ersek Cardiovascular and Thoracic Surgery Research and Training Hospital, Istanbul, Turkey","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076400887","display_name":"Emre Aru\u011faslan","orcid":"https://orcid.org/0000-0001-7441-3367","observed_orcids":["https://orcid.org/0000-0001-7441-3367"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Emre Aru\u011faslan","raw_affiliation_strings":["Division of Cardiology, Dr. Siyami Ersek Cardiovascular and Thoracic Surgery Research and Training Hospital, Istanbul, Turkey"],"raw_orcid":"https://orcid.org/0000-0001-7441-3367","affiliations":[{"raw_affiliation_string":"Division of Cardiology, Dr. Siyami Ersek Cardiovascular and Thoracic Surgery Research and Training Hospital, Istanbul, Turkey","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055688355","display_name":"Tolga Sinan G\u00fcven\u00e7","orcid":"https://orcid.org/0000-0002-6738-266X","observed_orcids":["https://orcid.org/0000-0002-6738-266X"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Tolga Sinan G\u00fcven\u00e7","raw_affiliation_strings":["Division of Cardiology, Dr. Siyami Ersek Cardiovascular and Thoracic Surgery Research and Training Hospital, Istanbul, Turkey"],"raw_orcid":"https://orcid.org/0000-0002-6738-266X","affiliations":[{"raw_affiliation_string":"Division of Cardiology, Dr. Siyami Ersek Cardiovascular and Thoracic Surgery Research and Training Hospital, Istanbul, Turkey","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090879669","display_name":"Fatma \u00d6zpamuk Karadeniz","orcid":"https://orcid.org/0000-0001-5839-9104","observed_orcids":["https://orcid.org/0000-0001-5839-9104"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Fatma \u00d6zpamuk Karadeniz","raw_affiliation_strings":["Division of Cardiology, Dr. Siyami Ersek Cardiovascular and Thoracic Surgery Research and Training Hospital, Istanbul, Turkey"],"raw_orcid":"https://orcid.org/0000-0001-5839-9104","affiliations":[{"raw_affiliation_string":"Division of Cardiology, Dr. Siyami Ersek Cardiovascular and Thoracic Surgery Research and Training Hospital, Istanbul, Turkey","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023418275","display_name":"H\u00fclya Ka\u015f\u0131k\u00e7\u0131o\u011flu","orcid":"https://orcid.org/0000-0001-5366-7560","observed_orcids":["https://orcid.org/0000-0001-5366-7560"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"H\u00fclya Ka\u015f\u0131k\u00e7\u0131o\u011flu","raw_affiliation_strings":["Division of Cardiology, Dr. Siyami Ersek Cardiovascular and Thoracic Surgery Research and Training Hospital, Istanbul, Turkey"],"raw_orcid":"https://orcid.org/0000-0001-5366-7560","affiliations":[{"raw_affiliation_string":"Division of Cardiology, Dr. Siyami Ersek Cardiovascular and Thoracic Surgery Research and Training Hospital, Istanbul, Turkey","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5026846393","display_name":"Ne\u015fe \u00c7am","orcid":"https://orcid.org/0000-0001-5812-1639","observed_orcids":["https://orcid.org/0000-0001-5812-1639"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ne\u015fe \u00c7am","raw_affiliation_strings":["Division of Cardiology, Dr. Siyami Ersek Cardiovascular and Thoracic Surgery Research and Training Hospital, Istanbul, Turkey"],"raw_orcid":"https://orcid.org/0000-0001-5812-1639","affiliations":[{"raw_affiliation_string":"Division of Cardiology, Dr. Siyami Ersek Cardiovascular and Thoracic Surgery Research and Training Hospital, Istanbul, Turkey","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5055688355"],"corresponding_institution_ids":[],"apc_list":{"value":2190,"currency":"USD","value_usd":2190},"apc_paid":{"value":2190,"currency":"USD","value_usd":2190},"fwci":0.3238,"has_fulltext":true,"cited_by_count":5,"citation_normalized_percentile":{"value":0.56892887,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"28","issue":"4","first_page":"267","last_page":"267"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10172","display_name":"Cardiac Valve Diseases and Treatments","score":0.9365000128746033,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10172","display_name":"Cardiac Valve Diseases and Treatments","score":0.9365000128746033,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10821","display_name":"Cardiovascular Function and Risk Factors","score":0.05939999967813492,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10372","display_name":"Cardiac Imaging and Diagnostics","score":0.001500000013038516,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/myocardial-efficiency","display_name":"myocardial efficiency","score":0.9769999980926514},{"id":"https://openalex.org/keywords/asymptomatic-mitral-regurgitation","display_name":"asymptomatic mitral regurgitation","score":0.9129999876022339},{"id":"https://openalex.org/keywords/severe-mitral-regurgitation","display_name":"severe mitral regurgitation","score":0.9089999794960022},{"id":"https://openalex.org/keywords/left-ventricular-systolic-function","display_name":"left ventricular systolic function","score":0.8550000190734863},{"id":"https://openalex.org/keywords/preserved-ejection-fraction","display_name":"preserved ejection fraction","score":0.7620000243186951},{"id":"https://openalex.org/keywords/myocardial-oxygen-consumption","display_name":"myocardial oxygen consumption","score":0.8220000267028809},{"id":"https://openalex.org/keywords/external-work","display_name":"external work","score":0.7739999890327454},{"id":"https://openalex.org/keywords/beta-blockers","display_name":"beta-blockers","score":0.6790000200271606},{"id":"https://openalex.org/keywords/ace-inhibitors","display_name":"ACE inhibitors","score":0.8289999961853027},{"id":"https://openalex.org/keywords/angiotensin-receptor-blockers","display_name":"angiotensin receptor blockers","score":0.9150000214576721},{"id":"https://openalex.org/keywords/left-ventricular-mass","display_name":"left ventricular mass","score":0.777999997138977}],"concepts":[{"id":"https://openalex.org/C2777910003","wikidata":"https://www.wikidata.org/wiki/Q1707292","display_name":"Asymptomatic","level":2,"score":0.8542530536651611},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8294475078582764},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.7709740400314331},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.7304956912994385},{"id":"https://openalex.org/C78085059","wikidata":"https://www.wikidata.org/wiki/Q641303","display_name":"Ejection fraction","level":3,"score":0.7082693576812744},{"id":"https://openalex.org/C2993373945","wikidata":"https://www.wikidata.org/wiki/Q268292","display_name":"Mitral regurgitation","level":2,"score":0.6669485569000244},{"id":"https://openalex.org/C2778921608","wikidata":"https://www.wikidata.org/wiki/Q2002035","display_name":"Ventricle","level":2,"score":0.6566939353942871},{"id":"https://openalex.org/C80461066","wikidata":"https://www.wikidata.org/wiki/Q1698533","display_name":"Stroke volume","level":4,"score":0.4770885407924652},{"id":"https://openalex.org/C2778198053","wikidata":"https://www.wikidata.org/wiki/Q181754","display_name":"Heart failure","level":2,"score":0.33535832166671753}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.4250/jcvi.2020.0038","doi":"https://doi.org/10.4250/jcvi.2020.0038","is_oa":true,"landing_page_url":"https://doi.org/10.4250/jcvi.2020.0038","pdf_url":null,"source":{"id":"https://openalex.org/S4394735500","display_name":"Journal of Cardiovascular Imaging","issn_l":"2586-7296","issn":["2586-7296","2586-7210"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","kci-registered","ki-jl-1","poland-20","russia-white-list-2"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Cardiovascular Imaging","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:7572264","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC7572264/","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC7572264/pdf/","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Cardiovasc Imaging","raw_type":"Text"},{"id":"pmid:33086443","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/33086443","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of cardiovascular imaging","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.4250/jcvi.2020.0038","doi":"https://doi.org/10.4250/jcvi.2020.0038","is_oa":true,"landing_page_url":"https://doi.org/10.4250/jcvi.2020.0038","pdf_url":null,"source":{"id":"https://openalex.org/S4394735500","display_name":"Journal of Cardiovascular Imaging","issn_l":"2586-7296","issn":["2586-7296","2586-7210"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","kci-registered","ki-jl-1","poland-20","russia-white-list-2"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Cardiovascular Imaging","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.9907000064849854,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3042897403.pdf","grobid_xml":"https://content.openalex.org/works/W3042897403.grobid-xml"},"referenced_works_count":31,"referenced_works":["https://openalex.org/W1580653590","https://openalex.org/W1980322984","https://openalex.org/W1985540047","https://openalex.org/W2001829748","https://openalex.org/W2011419396","https://openalex.org/W2037217443","https://openalex.org/W2042293234","https://openalex.org/W2048147051","https://openalex.org/W2048425037","https://openalex.org/W2052623113","https://openalex.org/W2058441408","https://openalex.org/W2062601257","https://openalex.org/W2069811865","https://openalex.org/W2080457369","https://openalex.org/W2105472710","https://openalex.org/W2108825966","https://openalex.org/W2120536963","https://openalex.org/W2131340250","https://openalex.org/W2131969784","https://openalex.org/W2137514565","https://openalex.org/W2145950740","https://openalex.org/W2153219359","https://openalex.org/W2155329465","https://openalex.org/W2342499888","https://openalex.org/W2410758355","https://openalex.org/W2415529981","https://openalex.org/W2548597441","https://openalex.org/W2748823530","https://openalex.org/W2751630023","https://openalex.org/W2983419379","https://openalex.org/W4234305472"],"related_works":["https://openalex.org/W2999082016","https://openalex.org/W4386661475","https://openalex.org/W2070125410","https://openalex.org/W1967327308","https://openalex.org/W2027152514","https://openalex.org/W3109394847","https://openalex.org/W2999773076","https://openalex.org/W2561493984","https://openalex.org/W3023498591","https://openalex.org/W2036965384"],"abstract_inverted_index":{"BACKGROUND:":[0],"It":[1],"is":[2],"difficult":[3],"to":[4,60,133],"determine":[5],"left":[6,18,46,111],"ventricular":[7,19,112],"systolic":[8],"performance":[9],"in":[10,63,90,136,139,191],"patients":[11,64,79,121,192],"with":[12,65,80,122,193],"severe":[13,67,81,123,141,195],"mitral":[14],"regurgitation":[15],"(MR)":[16],"since":[17],"ejection":[20],"fraction":[21],"(EF)":[22],"could":[23],"be":[24],"preserved":[25,198],"until":[26],"the":[27,31,37,45,55,140],"end":[28],"stages":[29],"of":[30,39,50,77,145],"disease.":[32],"Myocardial":[33],"efficiency":[34],"(MEf)":[35],"describes":[36],"amount":[38],"external":[40],"work":[41],"(EW)":[42],"done":[43],"by":[44],"ventricle":[47],"per":[48],"unit":[49],"oxygen":[51],"consumed":[52],"(mVO\u2082).":[53],"In":[54],"present":[56],"study,":[57],"we":[58],"aimed":[59],"investigate":[61],"MEf":[62,144,187],"asymptomatic":[66,82,194],"MR":[68,83,142,196],"using":[69,97,107],"a":[70],"novel":[71],"echocardiographic":[72],"method.":[73],"METHODS:":[74],"A":[75],"total":[76,137],"27":[78],"and":[84,100,110,152,197],"26":[85],"healthy":[86],"volunteers":[87],"were":[88,148,159,164],"included":[89],"this":[91,129,170],"cross-sectional":[92],"study.":[93],"EW":[94],"was":[95,105,131,172,188],"measured":[96],"stroke":[98],"volume":[99],"blood":[101],"pressure,":[102],"while":[103],"mVO\u2082":[104,138],"estimated":[106],"double":[108],"product":[109],"mass.":[113],"RESULTS:":[114],"\u0305:":[115],"0.24,":[116],"95%":[117],"CI:":[118],"0.19-0.29":[119],"for":[120],"MR).":[124],"Further":[125],"analysis":[126],"showed":[127],"that":[128],"reduction":[130],"due":[132],"an":[134],"increase":[135],"group.":[143],"thepatients":[146],"who":[147,163],"both":[149],"on":[150,166],"\u03b2-blockers":[151],"angiotensin":[153],"converting":[154],"enzyme":[155],"inhibitors/angiotensin":[156],"receptor":[157],"blockers":[158],"higher":[160],"than":[161],"those":[162],"not":[165,173],"any":[167],"drugs,":[168],"but":[169],"difference":[171],"statistically":[174],"significant":[175],"(32%":[176],"\u00b1":[177,181],"15%":[178],"vs.":[179],"23%":[180],"9%,":[182],"p":[183],"=":[184],"0.41).":[185],"CONCLUSIONS:":[186],"significantly":[189],"lower":[190],"EF.":[199]},"counts_by_year":[{"year":2024,"cited_by_count":3},{"year":2022,"cited_by_count":1},{"year":2020,"cited_by_count":1}],"updated_date":"2026-11-13T13:42:25.865203","created_date":"2020-07-23T00:00:00"}