{"id":"https://openalex.org/W3042854618","doi":"https://doi.org/10.1089/neu.2019.6969","title":"Sliding Scoring of the Glasgow Outcome Scale-Extended as Primary Outcome in Traumatic Brain Injury Trials","display_name":"Sliding Scoring of the Glasgow Outcome Scale-Extended as Primary Outcome in Traumatic Brain Injury Trials","publication_year":2020,"publication_date":"2020-07-15","ids":{"openalex":"https://openalex.org/W3042854618","doi":"https://doi.org/10.1089/neu.2019.6969","mag":"3042854618","pmid":"https://pubmed.ncbi.nlm.nih.gov/32664792","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/7757546"},"language":"en","primary_location":{"id":"doi:10.1089/neu.2019.6969","doi":"https://doi.org/10.1089/neu.2019.6969","is_oa":false,"landing_page_url":"https://doi.org/10.1089/neu.2019.6969","pdf_url":null,"source":{"id":"https://openalex.org/S85864898","display_name":"Journal of Neurotrauma","issn_l":"0897-7151","issn":["0897-7151","1557-9042"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320443","host_organization_name":"Mary Ann Liebert, Inc.","host_organization_lineage":["https://openalex.org/P4310320443","https://openalex.org/P4310320017"],"host_organization_lineage_names":["Mary Ann Liebert, Inc.","SAGE Publishing"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Neurotrauma","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/7757546","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5033233067","display_name":"Sharon D. Yeatts","orcid":"https://orcid.org/0000-0001-9235-0670","observed_orcids":["https://orcid.org/0000-0001-9235-0670"]},"institutions":[{"id":"https://openalex.org/I153297377","display_name":"Medical University of South Carolina","ror":"https://ror.org/012jban78","country_code":"US","type":"education","lineage":["https://openalex.org/I153297377"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Sharon D. Yeatts","raw_affiliation_strings":["Department of Public Health Sciences, Medical University of South Carolina, Charleston, South Carolina, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Public Health Sciences, Medical University of South Carolina, Charleston, South Carolina, USA","institution_ids":["https://openalex.org/I153297377"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113690476","display_name":"Renee\u2019 Hebert Martin","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I153297377","display_name":"Medical University of South Carolina","ror":"https://ror.org/012jban78","country_code":"US","type":"education","lineage":["https://openalex.org/I153297377"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Rene\u00e9 H. Martin","raw_affiliation_strings":["Department of Public Health Sciences, Medical University of South Carolina, Charleston, South Carolina, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Public Health Sciences, Medical University of South Carolina, Charleston, South Carolina, USA","institution_ids":["https://openalex.org/I153297377"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051630792","display_name":"William J. Meurer","orcid":"https://orcid.org/0000-0002-1158-5302","observed_orcids":["https://orcid.org/0000-0002-1158-5302"]},"institutions":[{"id":"https://openalex.org/I27837315","display_name":"University of Michigan","ror":"https://ror.org/00jmfr291","country_code":"US","type":"education","lineage":["https://openalex.org/I27837315"]},{"id":"https://openalex.org/I4405267949","display_name":"Berry Consultants, LLC (United States)","ror":"https://ror.org/054btrt70","country_code":"US","type":"company","lineage":["https://openalex.org/I4405267949"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"William Meurer","raw_affiliation_strings":["Department of Emergency Medicine, University of Michigan. Ann Arbor, Michigan, USA","Visiting medical and statistical scientist, Berry Consultants, Austin, Texas, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Emergency Medicine, University of Michigan. Ann Arbor, Michigan, USA","institution_ids":["https://openalex.org/I27837315"]},{"raw_affiliation_string":"Visiting medical and statistical scientist, Berry Consultants, Austin, Texas, USA","institution_ids":["https://openalex.org/I4405267949"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043946098","display_name":"Robert Silbergleit","orcid":"https://orcid.org/0000-0003-4101-2430","observed_orcids":["https://orcid.org/0000-0003-4101-2430"]},"institutions":[{"id":"https://openalex.org/I27837315","display_name":"University of Michigan","ror":"https://ror.org/00jmfr291","country_code":"US","type":"education","lineage":["https://openalex.org/I27837315"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Robert Silbergleit","raw_affiliation_strings":["Department of Emergency Medicine, University of Michigan. Ann Arbor, Michigan, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Emergency Medicine, University of Michigan. Ann Arbor, Michigan, USA","institution_ids":["https://openalex.org/I27837315"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112881029","display_name":"Gaylan L. Rockswold","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I130238516","display_name":"University of Minnesota","ror":"https://ror.org/017zqws13","country_code":"US","type":"education","lineage":["https://openalex.org/I130238516"]},{"id":"https://openalex.org/I2802288015","display_name":"Hennepin County Medical Center","ror":"https://ror.org/01k7a6660","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2802288015"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Gaylan L. Rockswold","raw_affiliation_strings":["Department of Neurosurgery, University of Minnesota, Hennepin County Medical Center, Minneapolis, Minnesota, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurosurgery, University of Minnesota, Hennepin County Medical Center, Minneapolis, Minnesota, USA","institution_ids":["https://openalex.org/I130238516","https://openalex.org/I2802288015"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5107913862","display_name":"William G. Barsan","orcid":"https://orcid.org/0000-0002-6019-2062","observed_orcids":["https://orcid.org/0000-0002-6019-2062"]},"institutions":[{"id":"https://openalex.org/I27837315","display_name":"University of Michigan","ror":"https://ror.org/00jmfr291","country_code":"US","type":"education","lineage":["https://openalex.org/I27837315"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"William G. Barsan","raw_affiliation_strings":["Department of Emergency Medicine, University of Michigan. Ann Arbor, Michigan, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Emergency Medicine, University of Michigan. Ann Arbor, Michigan, USA","institution_ids":["https://openalex.org/I27837315"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008873543","display_name":"Frederick Kofi Korley","orcid":"https://orcid.org/0000-0003-4920-8278","observed_orcids":["https://orcid.org/0000-0003-4920-8278"]},"institutions":[{"id":"https://openalex.org/I27837315","display_name":"University of Michigan","ror":"https://ror.org/00jmfr291","country_code":"US","type":"education","lineage":["https://openalex.org/I27837315"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Frederick K. Korley","raw_affiliation_strings":["Department of Emergency Medicine, University of Michigan. Ann Arbor, Michigan, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Emergency Medicine, University of Michigan. Ann Arbor, Michigan, USA","institution_ids":["https://openalex.org/I27837315"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048093507","display_name":"David W. Wright","orcid":"https://orcid.org/0000-0002-7145-9105","observed_orcids":["https://orcid.org/0000-0002-7145-9105"]},"institutions":[{"id":"https://openalex.org/I150468666","display_name":"Emory University","ror":"https://ror.org/03czfpz43","country_code":"US","type":"education","lineage":["https://openalex.org/I150468666"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"David W. Wright","raw_affiliation_strings":["Department of Emergency Medicine, Emory University, Atlanta, Georgia, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Emergency Medicine, Emory University, Atlanta, Georgia, USA","institution_ids":["https://openalex.org/I150468666"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5004067964","display_name":"Byron J. Gajewski","orcid":"https://orcid.org/0000-0001-7589-8247","observed_orcids":["https://orcid.org/0000-0001-7589-8247"]},"institutions":[{"id":"https://openalex.org/I4210128618","display_name":"University of Kansas Medical Center","ror":"https://ror.org/036c9yv20","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210128618"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Byron J. Gajewski","raw_affiliation_strings":["Department of Biostatistics & Data Science, University of Kansas Medical Center. Kansas City, Kansas, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biostatistics & Data Science, University of Kansas Medical Center. Kansas City, Kansas, USA","institution_ids":["https://openalex.org/I4210128618"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":7,"corresponding_author_ids":["https://openalex.org/A5033233067"],"corresponding_institution_ids":["https://openalex.org/I153297377"],"apc_list":null,"apc_paid":null,"fwci":3.0458,"has_fulltext":false,"cited_by_count":31,"citation_normalized_percentile":{"value":0.92148624,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":95,"max":99},"biblio":{"volume":"37","issue":"24","first_page":"2674","last_page":"2679"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10416","display_name":"Traumatic Brain Injury Research","score":0.5586000084877014,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10416","display_name":"Traumatic Brain Injury Research","score":0.5586000084877014,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10706","display_name":"Traumatic Brain Injury and Neurovascular Disturbances","score":0.2003999948501587,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11235","display_name":"Statistical Methods in Clinical Trials","score":0.17710000276565552,"subfield":{"id":"https://openalex.org/subfields/2613","display_name":"Statistics and Probability"},"field":{"id":"https://openalex.org/fields/26","display_name":"Mathematics"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/extended-glasgow-outcome-scale","display_name":"Glasgow Outcome Scale-Extended","score":0.9940000176429749},{"id":"https://openalex.org/keywords/traumatic-brain-injury","display_name":"traumatic brain injury","score":0.9660000205039978},{"id":"https://openalex.org/keywords/dichotomization","display_name":"dichotomization","score":0.8389999866485596},{"id":"https://openalex.org/keywords/statistical-power","display_name":"statistical power","score":0.7200000286102295},{"id":"https://openalex.org/keywords/clinical-trial-outcome-measures","display_name":"clinical trial outcome measures","score":0.5059999823570251}],"concepts":[{"id":"https://openalex.org/C2777796830","wikidata":"https://www.wikidata.org/wiki/Q1529519","display_name":"Glasgow Outcome Scale","level":3,"score":0.7771256566047668},{"id":"https://openalex.org/C148220186","wikidata":"https://www.wikidata.org/wiki/Q7111912","display_name":"Outcome (game theory)","level":2,"score":0.7602338790893555},{"id":"https://openalex.org/C17624336","wikidata":"https://www.wikidata.org/wiki/Q461644","display_name":"Glasgow Coma Scale","level":2,"score":0.5536108613014221},{"id":"https://openalex.org/C2781017439","wikidata":"https://www.wikidata.org/wiki/Q1995526","display_name":"Traumatic brain injury","level":2,"score":0.549633264541626},{"id":"https://openalex.org/C2909711754","wikidata":"https://www.wikidata.org/wiki/Q7100785","display_name":"Ordinal Scale","level":2,"score":0.4771541953086853},{"id":"https://openalex.org/C2778755073","wikidata":"https://www.wikidata.org/wiki/Q10858537","display_name":"Scale (ratio)","level":2,"score":0.4701386094093323},{"id":"https://openalex.org/C96608239","wikidata":"https://www.wikidata.org/wiki/Q1199823","display_name":"Statistical power","level":2,"score":0.4657045006752014},{"id":"https://openalex.org/C535046627","wikidata":"https://www.wikidata.org/wiki/Q30612","display_name":"Clinical trial","level":2,"score":0.44634342193603516},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.44480735063552856},{"id":"https://openalex.org/C105795698","wikidata":"https://www.wikidata.org/wiki/Q12483","display_name":"Statistics","level":1,"score":0.3675283193588257},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.35080093145370483},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.21525663137435913},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.20695775747299194},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.18222078680992126},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.0},{"id":"https://openalex.org/C144237770","wikidata":"https://www.wikidata.org/wiki/Q747534","display_name":"Mathematical economics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000070642","descriptor_name":"Brain Injuries, Traumatic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D002986","descriptor_name":"Clinical Trials as Topic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017063","descriptor_name":"Outcome Assessment, Health Care","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D023261","descriptor_name":"Glasgow Outcome Scale","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1089/neu.2019.6969","doi":"https://doi.org/10.1089/neu.2019.6969","is_oa":false,"landing_page_url":"https://doi.org/10.1089/neu.2019.6969","pdf_url":null,"source":{"id":"https://openalex.org/S85864898","display_name":"Journal of Neurotrauma","issn_l":"0897-7151","issn":["0897-7151","1557-9042"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320443","host_organization_name":"Mary Ann Liebert, Inc.","host_organization_lineage":["https://openalex.org/P4310320443","https://openalex.org/P4310320017"],"host_organization_lineage_names":["Mary Ann Liebert, Inc.","SAGE Publishing"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Neurotrauma","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:7757546","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/7757546","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Neurotrauma","raw_type":"Text"},{"id":"pmid:32664792","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/32664792","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of neurotrauma","raw_type":"Journal Article"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:7757546","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/7757546","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Neurotrauma","raw_type":"Text"},"sustainable_development_goals":[{"score":0.9537000060081482,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G4015404321","display_name":"Hyperbaric Oxygen BrainInjury Treatment (HOBIT) Trial-SDMC","funder_award_id":"U01NS095814","funder_id":"https://openalex.org/F4320337359","funder_display_name":"National Institute of Neurological Disorders and Stroke"},{"id":"https://openalex.org/G553180121","display_name":"ProTECT III","funder_award_id":"U01NS062778","funder_id":"https://openalex.org/F4320337359","funder_display_name":"National Institute of Neurological Disorders and Stroke"},{"id":"https://openalex.org/G9000860230","display_name":"Brain Oxygen Optimization in Severe Traumatic Brain Injury - Phase 3 (BOOST-3)","funder_award_id":"U01NS099046","funder_id":"https://openalex.org/F4320337359","funder_display_name":"National Institute of Neurological Disorders and Stroke"},{"id":"https://openalex.org/G9000890610","display_name":"Strategies to Innovate EmeRgENcy Care Clinical Trials Network (SIREN) - Data Coordinating Center","funder_award_id":"U24NS100655","funder_id":"https://openalex.org/F4320337359","funder_display_name":"National Institute of Neurological Disorders and Stroke"},{"id":"https://openalex.org/G9000902219","display_name":"Hyperbaric Oxygen Brain Injury Treatment (HOBIT) Trial","funder_award_id":"U01NS095926","funder_id":"https://openalex.org/F4320337359","funder_display_name":"National Institute of Neurological Disorders and Stroke"}],"funders":[{"id":"https://openalex.org/F4320337359","display_name":"National Institute of Neurological Disorders and Stroke","ror":"https://ror.org/01s5ya894"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":11,"referenced_works":["https://openalex.org/W1969298821","https://openalex.org/W1989883289","https://openalex.org/W2000271449","https://openalex.org/W2039885590","https://openalex.org/W2070921889","https://openalex.org/W2103367163","https://openalex.org/W2161864397","https://openalex.org/W2166531273","https://openalex.org/W2515100021","https://openalex.org/W2794265807","https://openalex.org/W2944255357"],"related_works":["https://openalex.org/W4386019661","https://openalex.org/W2103367163","https://openalex.org/W2938339820","https://openalex.org/W4385680740","https://openalex.org/W24175099","https://openalex.org/W1963886662","https://openalex.org/W2000271449","https://openalex.org/W7117324252","https://openalex.org/W2095772867","https://openalex.org/W2166537310"],"abstract_inverted_index":{"The":[0,119,137],"Glasgow":[1],"Outcome":[2],"Scale-Extended":[3],"(GOS-E),":[4],"an":[5,101,208],"ordinal":[6],"scale":[7],"measuring":[8],"global":[9],"outcome,":[10],"is":[11,27,80,121,148,159],"used":[12],"commonly":[13],"as":[14],"the":[15,45,65,77,85,89,108,113,116,125,130,134,142,157,167,179,193],"primary":[16],"outcome":[17,55,69],"measure":[18],"in":[19],"clinical":[20],"trials":[21],"of":[22,41,47,67,115,127,144,192,195],"traumatic":[23],"brain":[24],"injury.":[25],"Analysis":[26],"often":[28],"based":[29,123],"on":[30,124,166],"a":[31,61,103],"dichotomization":[32,52],"and":[33,95,133,173,207],"thus":[34],"has":[35],"inherent":[36],"statistical":[37,162],"limitations,":[38],"including":[39],"loss":[40],"information":[42],"related":[43],"to":[44,71,111,151],"collapse":[46],"adjacent":[48],"categories.":[49],"A":[50,185],"fixed":[51,86],"defines":[53],"favorable":[54,68,135],"consistently":[56],"for":[57,107,171,182,190,200],"all":[58],"subjects,":[59],"whereas":[60],"sliding":[62,78,90,104,117,186],"dichotomy":[63,79,91],"tailors":[64],"definition":[66],"according":[70,150],"baseline":[72,154],"prognosis/severity.":[73],"Literature":[74],"indicates":[75],"that":[76],"more":[81],"statistically":[82],"efficient":[83],"than":[84],"dichotomy;":[87],"however,":[88],"still":[92,198],"collapses":[93],"categories":[94],"therefore":[96],"discards":[97],"information.":[98],"We":[99],"propose":[100],"alternative,":[102],"scoring":[105,139],"system":[106,140],"GOS-E,":[109],"intended":[110],"address":[112],"limitations":[114],"dichotomy.":[118],"score":[120,132,158,187],"assigned":[122],"number":[126],"levels":[128],"between":[129],"achieved":[131],"cut-point.":[136],"proposed":[138],"reflects":[141],"magnitude":[143,194],"change,":[145],"where":[146],"change":[147,196],"defined":[149],"each":[152],"subject's":[153],"prognosis.":[155,201],"Because":[156],"approximately":[160],"continuous,":[161],"methods":[163],"can":[164],"rely":[165],"normal":[168],"distribution,":[169],"both":[170],"analysis":[172],"study":[174],"design.":[175],"Two":[176],"examples":[177],"show":[178],"corresponding":[180],"potential":[181],"improved":[183],"power.":[184],"approach":[188],"allows":[189],"quantification":[191],"while":[197],"accounting":[199],"Scientific":[202],"advantages":[203],"include":[204],"increased":[205],"power":[206],"intuitive":[209],"interpretation.":[210]},"counts_by_year":[{"year":2026,"cited_by_count":5},{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":6},{"year":2023,"cited_by_count":8},{"year":2022,"cited_by_count":6},{"year":2021,"cited_by_count":3}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2020-07-23T00:00:00"}