{"id":"https://openalex.org/W3041925007","doi":"https://doi.org/10.1002/anie.201915826","title":"Smart Design of Nanomaterials for Mitochondria\u2010Targeted Nanotherapeutics","display_name":"Smart Design of Nanomaterials for Mitochondria\u2010Targeted Nanotherapeutics","publication_year":2020,"publication_date":"2020-03-04","ids":{"openalex":"https://openalex.org/W3041925007","doi":"https://doi.org/10.1002/anie.201915826","mag":"3041925007","pmid":"https://pubmed.ncbi.nlm.nih.gov/32128948"},"language":"en","primary_location":{"id":"doi:10.1002/anie.201915826","doi":"https://doi.org/10.1002/anie.201915826","is_oa":false,"landing_page_url":"https://doi.org/10.1002/anie.201915826","pdf_url":null,"source":{"id":"https://openalex.org/S67393510","display_name":"Angewandte Chemie International Edition","issn_l":"1433-7851","issn":["1433-7851","1521-3773"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","jufo-3","ki-jl-2","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Angewandte Chemie International Edition","raw_type":"journal-article"},"parent_works":[],"lineage":["https://openalex.org/W3041925007"],"child_works_count":0,"type":"review","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5018656921","display_name":"Si Si Liew","orcid":"https://orcid.org/0000-0002-1709-9778","observed_orcids":["https://orcid.org/0000-0002-1709-9778"]},"institutions":[{"id":"https://openalex.org/I165932596","display_name":"National University of Singapore","ror":"https://ror.org/01tgyzw49","country_code":"SG","type":"education","lineage":["https://openalex.org/I165932596"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"Si Si Liew","raw_affiliation_strings":["Department of Chemistry, National University of Singapore, Singapore, 117543 Singapore","These authors contributed equally to this work"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, National University of Singapore, Singapore, 117543 Singapore","institution_ids":["https://openalex.org/I165932596"]},{"raw_affiliation_string":"These authors contributed equally to this work","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030686271","display_name":"Xiaofei Qin","orcid":"https://orcid.org/0000-0002-8327-8221","observed_orcids":["https://orcid.org/0000-0002-8327-8221","https://orcid.org/0009-0007-5132-360X"]},"institutions":[{"id":"https://openalex.org/I134687103","display_name":"Nanjing Tech University","ror":"https://ror.org/03sd35x91","country_code":"CN","type":"education","lineage":["https://openalex.org/I134687103"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Xiaofei Qin","raw_affiliation_strings":["Key Laboratory of Flexible Electronics (KLOFE) & Institute of Advanced Materials (IAM) Nanjing Tech University Nanjing 211816 P. R. China","These authors contributed equally to this work"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Key Laboratory of Flexible Electronics (KLOFE) & Institute of Advanced Materials (IAM) Nanjing Tech University Nanjing 211816 P. R. China","institution_ids":["https://openalex.org/I134687103"]},{"raw_affiliation_string":"These authors contributed equally to this work","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018158708","display_name":"Jia Zhou","orcid":"https://orcid.org/0000-0001-7168-5690","observed_orcids":["https://orcid.org/0000-0001-7168-5690"]},"institutions":[{"id":"https://openalex.org/I134687103","display_name":"Nanjing Tech University","ror":"https://ror.org/03sd35x91","country_code":"CN","type":"education","lineage":["https://openalex.org/I134687103"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jia Zhou","raw_affiliation_strings":["Key Laboratory of Flexible Electronics (KLOFE) & Institute of Advanced Materials (IAM) Nanjing Tech University Nanjing 211816 P. R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Key Laboratory of Flexible Electronics (KLOFE) & Institute of Advanced Materials (IAM) Nanjing Tech University Nanjing 211816 P. R. China","institution_ids":["https://openalex.org/I134687103"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100412926","display_name":"Lin Li","orcid":"https://orcid.org/0000-0003-0426-6546","observed_orcids":["https://orcid.org/0000-0003-0426-6546","https://orcid.org/0009-0006-4540-8271","https://orcid.org/0000-0001-7240-8150"]},"institutions":[{"id":"https://openalex.org/I134687103","display_name":"Nanjing Tech University","ror":"https://ror.org/03sd35x91","country_code":"CN","type":"education","lineage":["https://openalex.org/I134687103"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Lin Li","raw_affiliation_strings":["Key Laboratory of Flexible Electronics (KLOFE) & Institute of Advanced Materials (IAM) Nanjing Tech University Nanjing 211816 P. R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Key Laboratory of Flexible Electronics (KLOFE) & Institute of Advanced Materials (IAM) Nanjing Tech University Nanjing 211816 P. R. China","institution_ids":["https://openalex.org/I134687103"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100352881","display_name":"Wei Huang","orcid":"https://orcid.org/0000-0001-7004-6408","observed_orcids":["https://orcid.org/0000-0001-7004-6408","https://orcid.org/0000-0002-5852-3264","https://orcid.org/0009-0002-3081-4518","https://orcid.org/0009-0006-3744-3480","https://orcid.org/0009-0009-9834-4031","https://orcid.org/0000-0002-0095-1354"]},"institutions":[{"id":"https://openalex.org/I134687103","display_name":"Nanjing Tech University","ror":"https://ror.org/03sd35x91","country_code":"CN","type":"education","lineage":["https://openalex.org/I134687103"]},{"id":"https://openalex.org/I17145004","display_name":"Northwestern Polytechnical University","ror":"https://ror.org/01y0j0j86","country_code":"CN","type":"education","lineage":["https://openalex.org/I17145004"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Wei Huang","raw_affiliation_strings":["Key Laboratory of Flexible Electronics (KLOFE) & Institute of Advanced Materials (IAM) Nanjing Tech University Nanjing 211816 P. R. China","Shaanxi Institute of Flexible Electronics (SIFE), Northwestern Polytechnical University, Xi'an, 710072 P. R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Key Laboratory of Flexible Electronics (KLOFE) & Institute of Advanced Materials (IAM) Nanjing Tech University Nanjing 211816 P. R. China","institution_ids":["https://openalex.org/I134687103"]},{"raw_affiliation_string":"Shaanxi Institute of Flexible Electronics (SIFE), Northwestern Polytechnical University, Xi'an, 710072 P. R. China","institution_ids":["https://openalex.org/I17145004"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5021926450","display_name":"Shao Qin Yao","orcid":"https://orcid.org/0000-0003-4715-769X","observed_orcids":["https://orcid.org/0000-0003-4715-769X"]},"institutions":[{"id":"https://openalex.org/I165932596","display_name":"National University of Singapore","ror":"https://ror.org/01tgyzw49","country_code":"SG","type":"education","lineage":["https://openalex.org/I165932596"]}],"countries":["SG"],"is_corresponding":true,"raw_author_name":"Shao Q. Yao","raw_affiliation_strings":["Department of Chemistry, National University of Singapore, Singapore, 117543 Singapore"],"raw_orcid":"https://orcid.org/0000-0003-4715-769X","affiliations":[{"raw_affiliation_string":"Department of Chemistry, National University of Singapore, Singapore, 117543 Singapore","institution_ids":["https://openalex.org/I165932596"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5021926450","https://openalex.org/A5030686271","https://openalex.org/A5100412926"],"corresponding_institution_ids":["https://openalex.org/I134687103","https://openalex.org/I165932596"],"apc_list":{"value":5000,"currency":"USD","value_usd":5000},"apc_paid":null,"fwci":2.0384,"has_fulltext":false,"cited_by_count":298,"citation_normalized_percentile":{"value":0.88608338,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":97,"max":100},"biblio":{"volume":"60","issue":"5","first_page":"2232","last_page":"2256"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10063","display_name":"Nanoparticle-Based Drug Delivery","score":0.9804999828338623,"subfield":{"id":"https://openalex.org/subfields/2502","display_name":"Biomaterials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10063","display_name":"Nanoparticle-Based Drug Delivery","score":0.9804999828338623,"subfield":{"id":"https://openalex.org/subfields/2502","display_name":"Biomaterials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10782","display_name":"Nanoplatforms for cancer theranostics","score":0.01720000058412552,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10725","display_name":"RNA Interference and Gene Delivery","score":0.0006000000284984708,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/mitochondria","display_name":"mitochondria","score":0.5460000038146973},{"id":"https://openalex.org/keywords/nanocarriers","display_name":"nanocarriers","score":0.8109999895095825},{"id":"https://openalex.org/keywords/subcellular-targeting","display_name":"subcellular targeting","score":0.8759999871253967},{"id":"https://openalex.org/keywords/stimuli-responsive-drug-delivery","display_name":"stimuli-responsive drug delivery","score":0.8809999823570251},{"id":"https://openalex.org/keywords/controlled-release","display_name":"controlled release","score":0.925000011920929},{"id":"https://openalex.org/keywords/synergistic-therapy","display_name":"synergistic therapy","score":0.7850000262260437},{"id":"https://openalex.org/keywords/mitochondrial-dysfunction","display_name":"mitochondrial dysfunction","score":0.7110000252723694},{"id":"https://openalex.org/keywords/mitochondrial-disease","display_name":"mitochondrial disease","score":0.6060000061988831},{"id":"https://openalex.org/keywords/chemotherapy","display_name":"chemotherapy","score":0.4099999964237213},{"id":"https://openalex.org/keywords/gene-therapy","display_name":"gene therapy","score":0.7749999761581421},{"id":"https://openalex.org/keywords/phototherapy","display_name":"phototherapy","score":0.9950000047683716}],"concepts":[{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.6149408221244812},{"id":"https://openalex.org/C138631740","wikidata":"https://www.wikidata.org/wiki/Q967847","display_name":"Nanomaterials","level":2,"score":0.5899111032485962},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.41224658489227295},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.2721692621707916}],"mesh":[{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008928","descriptor_name":"Mitochondria","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D049329","descriptor_name":"Nanostructures","qualifier_ui":"Q000592","qualifier_name":"standards","is_major_topic":true},{"descriptor_ui":"D053758","descriptor_name":"Nanoparticles","qualifier_ui":"Q000592","qualifier_name":"standards","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1002/anie.201915826","doi":"https://doi.org/10.1002/anie.201915826","is_oa":false,"landing_page_url":"https://doi.org/10.1002/anie.201915826","pdf_url":null,"source":{"id":"https://openalex.org/S67393510","display_name":"Angewandte Chemie International Edition","issn_l":"1433-7851","issn":["1433-7851","1521-3773"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","jufo-3","ki-jl-2","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Angewandte Chemie International Edition","raw_type":"journal-article"},{"id":"pmid:32128948","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/32128948","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Angewandte Chemie (International ed. in English)","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.8048999905586243,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G2153542510","display_name":null,"funder_award_id":"81672508","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G361457543","display_name":null,"funder_award_id":"SBP-4","funder_id":"https://openalex.org/F4320320709","funder_display_name":"National Research Foundation Singapore"},{"id":"https://openalex.org/G8592850575","display_name":null,"funder_award_id":"SBP-8","funder_id":"https://openalex.org/F4320320709","funder_display_name":"National Research Foundation Singapore"}],"funders":[{"id":"https://openalex.org/F4320320709","display_name":"National Research Foundation Singapore","ror":"https://ror.org/03cpyc314"},{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":196,"referenced_works":["https://openalex.org/W270877285","https://openalex.org/W1483161728","https://openalex.org/W1499809894","https://openalex.org/W1549152014","https://openalex.org/W1752114428","https://openalex.org/W1798798079","https://openalex.org/W1812701728","https://openalex.org/W1835614080","https://openalex.org/W1838335582","https://openalex.org/W1840083634","https://openalex.org/W1964894520","https://openalex.org/W1966237056","https://openalex.org/W1967507489","https://openalex.org/W1968296717","https://openalex.org/W1969690844","https://openalex.org/W1969795416","https://openalex.org/W1972261070","https://openalex.org/W1973205178","https://openalex.org/W1974839200","https://openalex.org/W1976041621","https://openalex.org/W1977116179","https://openalex.org/W1987885263","https://openalex.org/W1988660932","https://openalex.org/W1992423211","https://openalex.org/W1993707696","https://openalex.org/W2004934153","https://openalex.org/W2008188065","https://openalex.org/W2010247113","https://openalex.org/W2010625981","https://openalex.org/W2012989300","https://openalex.org/W2015534555","https://openalex.org/W2017695333","https://openalex.org/W2018478612","https://openalex.org/W2020439084","https://openalex.org/W2020491649","https://openalex.org/W2021651355","https://openalex.org/W2021680808","https://openalex.org/W2025034309","https://openalex.org/W2030855909","https://openalex.org/W2034414337","https://openalex.org/W2034773856","https://openalex.org/W2036521660","https://openalex.org/W2041851797","https://openalex.org/W2044079387","https://openalex.org/W2050833801","https://openalex.org/W2054114673","https://openalex.org/W2055456981","https://openalex.org/W2057472478","https://openalex.org/W2064758958","https://openalex.org/W2068973847","https://openalex.org/W2070554086","https://openalex.org/W2070671832","https://openalex.org/W2073419642","https://openalex.org/W2075225565","https://openalex.org/W2080503518","https://openalex.org/W2089982008","https://openalex.org/W2110063847","https://openalex.org/W2117692326","https://openalex.org/W2118852769","https://openalex.org/W2131415852","https://openalex.org/W2135198179","https://openalex.org/W2135664206","https://openalex.org/W2136609330","https://openalex.org/W2140525205","https://openalex.org/W2142771852","https://openalex.org/W2144277227","https://openalex.org/W2149797564","https://openalex.org/W2149959721","https://openalex.org/W2150048195","https://openalex.org/W2151643050","https://openalex.org/W2157406719","https://openalex.org/W2160693099","https://openalex.org/W2162496259","https://openalex.org/W2167044450","https://openalex.org/W2167370588","https://openalex.org/W2169817108","https://openalex.org/W2169846877","https://openalex.org/W2170663303","https://openalex.org/W2198220706","https://openalex.org/W2310415701","https://openalex.org/W2319084466","https://openalex.org/W2328082795","https://openalex.org/W2331561938","https://openalex.org/W2360183543","https://openalex.org/W2418785783","https://openalex.org/W2461343806","https://openalex.org/W2466097311","https://openalex.org/W2475582934","https://openalex.org/W2495541981","https://openalex.org/W2512659970","https://openalex.org/W2514833799","https://openalex.org/W2518509288","https://openalex.org/W2522229560","https://openalex.org/W2546600895","https://openalex.org/W2549641338","https://openalex.org/W2558943593","https://openalex.org/W2578281794","https://openalex.org/W2584318012","https://openalex.org/W2588612858","https://openalex.org/W2592130829","https://openalex.org/W2603905918","https://openalex.org/W2612876306","https://openalex.org/W2613630131","https://openalex.org/W2613959205","https://openalex.org/W2619181032","https://openalex.org/W2619447650","https://openalex.org/W2620095014","https://openalex.org/W2685411876","https://openalex.org/W2732239116","https://openalex.org/W2734768350","https://openalex.org/W2735325266","https://openalex.org/W2740024487","https://openalex.org/W2740915638","https://openalex.org/W2742204633","https://openalex.org/W2742984768","https://openalex.org/W2747306484","https://openalex.org/W2755338234","https://openalex.org/W2761967589","https://openalex.org/W2766032796","https://openalex.org/W2767722274","https://openalex.org/W2767956479","https://openalex.org/W2770166811","https://openalex.org/W2770541814","https://openalex.org/W2770597671","https://openalex.org/W2775396772","https://openalex.org/W2784751183","https://openalex.org/W2785041057","https://openalex.org/W2788842288","https://openalex.org/W2788964184","https://openalex.org/W2790495478","https://openalex.org/W2790503428","https://openalex.org/W2793311199","https://openalex.org/W2793703146","https://openalex.org/W2795868770","https://openalex.org/W2796064422","https://openalex.org/W2803235708","https://openalex.org/W2803792074","https://openalex.org/W2805624613","https://openalex.org/W2807135845","https://openalex.org/W2809136880","https://openalex.org/W2809234829","https://openalex.org/W2871666084","https://openalex.org/W2876116501","https://openalex.org/W2887344124","https://openalex.org/W2888444871","https://openalex.org/W2890187629","https://openalex.org/W2890879687","https://openalex.org/W2891993984","https://openalex.org/W2892137211","https://openalex.org/W2894800710","https://openalex.org/W2897382512","https://openalex.org/W2897416241","https://openalex.org/W2898162515","https://openalex.org/W2898479332","https://openalex.org/W2899241243","https://openalex.org/W2901019629","https://openalex.org/W2901745493","https://openalex.org/W2904797888","https://openalex.org/W2904832380","https://openalex.org/W2912665154","https://openalex.org/W2913185045","https://openalex.org/W2916762679","https://openalex.org/W2917829292","https://openalex.org/W2918684851","https://openalex.org/W2918768980","https://openalex.org/W2918869495","https://openalex.org/W2922612647","https://openalex.org/W2923076973","https://openalex.org/W2935826504","https://openalex.org/W2938196301","https://openalex.org/W2938224419","https://openalex.org/W2938678031","https://openalex.org/W2947323858","https://openalex.org/W2953997005","https://openalex.org/W2963673788","https://openalex.org/W2972795010","https://openalex.org/W2980622391","https://openalex.org/W4210476933","https://openalex.org/W4236324949","https://openalex.org/W4238495951","https://openalex.org/W4238864742","https://openalex.org/W4239403073","https://openalex.org/W4240776096","https://openalex.org/W4243697734","https://openalex.org/W4246187371","https://openalex.org/W4252871639","https://openalex.org/W6600050674","https://openalex.org/W6600424091","https://openalex.org/W6600553734","https://openalex.org/W6600577311","https://openalex.org/W6601566456","https://openalex.org/W6602617507","https://openalex.org/W6602629387","https://openalex.org/W6632967960","https://openalex.org/W6699206226","https://openalex.org/W6917542048"],"related_works":["https://openalex.org/W3088695104","https://openalex.org/W4214771862","https://openalex.org/W4403501819","https://openalex.org/W7118347373","https://openalex.org/W2116950929","https://openalex.org/W4416576480","https://openalex.org/W2991612952","https://openalex.org/W2010625981","https://openalex.org/W4391543254","https://openalex.org/W2936170175"],"abstract_inverted_index":{"Mitochondria":[0],"are":[1,7,142],"the":[2,31,56,79,94,119,128,149],"powerhouse":[3],"of":[4,17,27,59,89,106,131,152],"cells.":[5],"They":[6],"vital":[8],"organelles":[9],"that":[10],"maintain":[11],"cellular":[12,43],"function":[13],"and":[14,45,68,112,124,138,145],"metabolism.":[15],"Dysfunction":[16],"mitochondria":[18],"results":[19],"in":[20,74,127],"various":[21,70],"diseases":[22],"with":[23,81],"a":[24,104],"great":[25],"diversity":[26],"clinical":[28],"appearances.":[29],"In":[30,114],"past,":[32],"strategies":[33,52,125],"have":[34,53],"been":[35],"developed":[36],"for":[37,55,121,133],"fabricating":[38],"subcellular-targeting":[39],"drug-delivery":[40],"nanocarriers,":[41],"enabling":[42],"internalization":[44],"subsequent":[46],"organelle":[47,80],"localization.":[48],"Of":[49],"late,":[50],"innovative":[51],"emerged":[54],"smart":[57,129],"design":[58,130],"multifunctional":[60],"nanocarriers.":[61],"Hierarchical":[62],"targeting":[63],"enables":[64],"nanocarriers":[65,85,132],"to":[66,77,91,147],"evade":[67],"overcome":[69],"barriers":[71],"encountered":[72],"upon":[73],"vivo":[75],"administration":[76],"reach":[78],"good":[82],"bioavailability.":[83],"Stimuli-responsive":[84],"allow":[86],"controlled":[87],"release":[88],"therapeutics":[90],"occur":[92],"at":[93],"desired":[95],"target":[96],"site.":[97],"Synergistic":[98],"therapy":[99],"can":[100],"be":[101],"achieved":[102],"using":[103],"combination":[105],"approaches":[107],"such":[108],"as":[109],"chemotherapy,":[110],"gene":[111],"phototherapy.":[113],"this":[115],"Review,":[116],"we":[117],"survey":[118],"field":[120],"recent":[122],"developments":[123],"used":[126],"mitochondria-targeted":[134],"therapeutics.":[135],"Existing":[136],"challenges":[137],"unexplored":[139],"therapeutic":[140],"opportunities":[141],"also":[143],"highlighted":[144],"discussed":[146],"inspire":[148],"next":[150],"generation":[151],"mitochondrial-targeting":[153],"nanotherapeutics.":[154]},"counts_by_year":[{"year":2026,"cited_by_count":44},{"year":2025,"cited_by_count":61},{"year":2024,"cited_by_count":64},{"year":2023,"cited_by_count":50},{"year":2022,"cited_by_count":35},{"year":2021,"cited_by_count":39},{"year":2020,"cited_by_count":5}],"updated_date":"2026-11-15T12:55:33.944570","created_date":"2020-07-16T00:00:00"}
