{"id":"https://openalex.org/W3039748972","doi":"https://doi.org/10.2147/dmso.s247351","title":"Comparative Effects of Curcumin versus Nano-Curcumin on Insulin Resistance, Serum Levels of Apelin and Lipid Profile in Type 2 Diabetic Rats","display_name":"Comparative Effects of Curcumin versus Nano-Curcumin on Insulin Resistance, Serum Levels of Apelin and Lipid Profile in Type 2 Diabetic Rats","publication_year":2020,"publication_date":"2020-07-01","ids":{"openalex":"https://openalex.org/W3039748972","doi":"https://doi.org/10.2147/dmso.s247351","mag":"3039748972","pmid":"https://pubmed.ncbi.nlm.nih.gov/32753918","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/7342486"},"language":"en","primary_location":{"id":"doi:10.2147/dmso.s247351","doi":"https://doi.org/10.2147/dmso.s247351","is_oa":true,"landing_page_url":"https://doi.org/10.2147/dmso.s247351","pdf_url":"https://www.dovepress.com/getfile.php?fileID=59406","source":{"id":"https://openalex.org/S176615914","display_name":"Diabetes Metabolic Syndrome and Obesity","issn_l":"1178-7007","issn":["1178-7007"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","doyens","jufo-1","ki-jl-1","norway-1","oarl","poland-100","russia-white-list-3","vabb-shw"],"host_organization":"https://openalex.org/P4310320348","host_organization_name":"Dove Medical Press","host_organization_lineage":["https://openalex.org/P4310320348","https://openalex.org/P4310320547"],"host_organization_lineage_names":["Dove Medical Press","Taylor & Francis"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.dovepress.com/getfile.php?fileID=59406","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5028520399","display_name":"Ali Shamsi\u2010Goushki","orcid":"https://orcid.org/0000-0001-8838-6339","observed_orcids":["https://orcid.org/0000-0001-8838-6339"]},"institutions":[{"id":"https://openalex.org/I4210133472","display_name":"Zahedan University of Medical Sciences","ror":"https://ror.org/03r42d171","country_code":"IR","type":"education","lineage":["https://openalex.org/I4210133472"]}],"countries":["IR"],"is_corresponding":false,"raw_author_name":"Ali Shamsi-Goushki","raw_affiliation_strings":["Department of Nutrition, School of Medicine, Zahedan University of Medical Sciences, Zahedan, Iran"],"raw_orcid":"https://orcid.org/0000-0001-8838-6339","affiliations":[{"raw_affiliation_string":"Department of Nutrition, School of Medicine, Zahedan University of Medical Sciences, Zahedan, Iran","institution_ids":["https://openalex.org/I4210133472"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019525328","display_name":"Zinat Mortazavi","orcid":"https://orcid.org/0000-0003-2563-5259","observed_orcids":["https://orcid.org/0000-0003-2563-5259"]},"institutions":[{"id":"https://openalex.org/I4210133472","display_name":"Zahedan University of Medical Sciences","ror":"https://ror.org/03r42d171","country_code":"IR","type":"education","lineage":["https://openalex.org/I4210133472"]}],"countries":["IR"],"is_corresponding":true,"raw_author_name":"Zinat Mortazavi","raw_affiliation_strings":["Health Promotion Research Center, Zahedan University of Medical Science, Zahedan, Iran"],"raw_orcid":"https://orcid.org/0000-0003-2563-5259","affiliations":[{"raw_affiliation_string":"Health Promotion Research Center, Zahedan University of Medical Science, Zahedan, Iran","institution_ids":["https://openalex.org/I4210133472"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022122513","display_name":"Mohammad Ali Mirshekar","orcid":"https://orcid.org/0000-0002-0449-6440","observed_orcids":["https://orcid.org/0000-0002-0449-6440"]},"institutions":[{"id":"https://openalex.org/I4210133472","display_name":"Zahedan University of Medical Sciences","ror":"https://ror.org/03r42d171","country_code":"IR","type":"education","lineage":["https://openalex.org/I4210133472"]}],"countries":["IR"],"is_corresponding":false,"raw_author_name":"Mohammad Ali Mirshekar","raw_affiliation_strings":["Clinical Immunology Research Center, Zahedan University of Medical Sciences, Zahedan, Iran"],"raw_orcid":"https://orcid.org/0000-0002-0449-6440","affiliations":[{"raw_affiliation_string":"Clinical Immunology Research Center, Zahedan University of Medical Sciences, Zahedan, Iran","institution_ids":["https://openalex.org/I4210133472"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018580564","display_name":"Mahdi Mohammadi","orcid":"https://orcid.org/0000-0001-9616-6125","observed_orcids":["https://orcid.org/0000-0001-9616-6125","https://orcid.org/0009-0004-5294-0886"]},"institutions":[{"id":"https://openalex.org/I4210133472","display_name":"Zahedan University of Medical Sciences","ror":"https://ror.org/03r42d171","country_code":"IR","type":"education","lineage":["https://openalex.org/I4210133472"]}],"countries":["IR"],"is_corresponding":false,"raw_author_name":"Mahdi Mohammadi","raw_affiliation_strings":["Health Promotion Research Center, Zahedan University of Medical Science, Zahedan, Iran"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Health Promotion Research Center, Zahedan University of Medical Science, Zahedan, Iran","institution_ids":["https://openalex.org/I4210133472"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038193505","display_name":"Nasrollah Moradikor","orcid":"https://orcid.org/0000-0001-9905-6845","observed_orcids":["https://orcid.org/0000-0001-9905-6845"]},"institutions":[{"id":"https://openalex.org/I4210154083","display_name":"Semnan University of Medical Sciences","ror":"https://ror.org/05y44as61","country_code":"IR","type":"education","lineage":["https://openalex.org/I4210154083"]}],"countries":["IR"],"is_corresponding":false,"raw_author_name":"Nasroallah Moradi-Kor","raw_affiliation_strings":["Research Centre of Physiology, Semnan University of Medical Sciences, Semnan, Iran"],"raw_orcid":"https://orcid.org/0000-0001-9905-6845","affiliations":[{"raw_affiliation_string":"Research Centre of Physiology, Semnan University of Medical Sciences, Semnan, Iran","institution_ids":["https://openalex.org/I4210154083"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061933867","display_name":"Saber Jafari-Maskouni","orcid":"https://orcid.org/0000-0001-9150-851X","observed_orcids":["https://orcid.org/0000-0001-9150-851X"]},"institutions":[{"id":"https://openalex.org/I4210133472","display_name":"Zahedan University of Medical Sciences","ror":"https://ror.org/03r42d171","country_code":"IR","type":"education","lineage":["https://openalex.org/I4210133472"]}],"countries":["IR"],"is_corresponding":false,"raw_author_name":"Saber Jafari-Maskouni","raw_affiliation_strings":["Department of Nutrition, School of Medicine, Zahedan University of Medical Sciences, Zahedan, Iran"],"raw_orcid":"https://orcid.org/0000-0001-9150-851X","affiliations":[{"raw_affiliation_string":"Department of Nutrition, School of Medicine, Zahedan University of Medical Sciences, Zahedan, Iran","institution_ids":["https://openalex.org/I4210133472"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5043668681","display_name":"Mansour Shahraki","orcid":"https://orcid.org/0000-0002-4345-9124","observed_orcids":["https://orcid.org/0000-0002-4345-9124"]},"institutions":[{"id":"https://openalex.org/I4210133472","display_name":"Zahedan University of Medical Sciences","ror":"https://ror.org/03r42d171","country_code":"IR","type":"education","lineage":["https://openalex.org/I4210133472"]}],"countries":["IR"],"is_corresponding":false,"raw_author_name":"Mansour Shahraki","raw_affiliation_strings":["Department of Nutrition, Zahedan University of Medical Sciences, Zahedan, Iran"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Nutrition, Zahedan University of Medical Sciences, Zahedan, Iran","institution_ids":["https://openalex.org/I4210133472"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5019525328"],"corresponding_institution_ids":["https://openalex.org/I4210133472"],"apc_list":{"value":2836,"currency":"USD","value_usd":2836},"apc_paid":{"value":2836,"currency":"USD","value_usd":2836},"fwci":2.7028,"has_fulltext":true,"cited_by_count":64,"citation_normalized_percentile":{"value":0.89898054,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"Volume 13","issue":null,"first_page":"2337","last_page":"2346"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11319","display_name":"Curcumin's Biomedical Applications","score":0.9731000065803528,"subfield":{"id":"https://openalex.org/subfields/1313","display_name":"Molecular Medicine"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11319","display_name":"Curcumin's Biomedical Applications","score":0.9731000065803528,"subfield":{"id":"https://openalex.org/subfields/1313","display_name":"Molecular Medicine"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11140","display_name":"Natural Antidiabetic Agents Studies","score":0.022700000554323196,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12059","display_name":"Berberine and alkaloids research","score":0.0006000000284984708,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/curcumin","display_name":"curcumin","score":0.9829999804496765},{"id":"https://openalex.org/keywords/nanocurcumin","display_name":"nanocurcumin","score":0.996999979019165},{"id":"https://openalex.org/keywords/type-2-diabetes","display_name":"type 2 diabetes","score":0.9599999785423279},{"id":"https://openalex.org/keywords/insulin-resistance","display_name":"insulin resistance","score":1.0},{"id":"https://openalex.org/keywords/apelin","display_name":"apelin","score":0.9990000128746033},{"id":"https://openalex.org/keywords/lipid-profile","display_name":"lipid profile","score":0.9350000023841858},{"id":"https://openalex.org/keywords/fasting-blood-glucose","display_name":"fasting blood glucose","score":0.8140000104904175},{"id":"https://openalex.org/keywords/hdl-cholesterol","display_name":"HDL cholesterol","score":0.7889999747276306},{"id":"https://openalex.org/keywords/ldl-cholesterol","display_name":"LDL cholesterol","score":0.6990000009536743},{"id":"https://openalex.org/keywords/triglycerides","display_name":"triglycerides","score":0.9430000185966492},{"id":"https://openalex.org/keywords/very-low-density-lipoprotein","display_name":"VLDL","score":0.6919999718666077},{"id":"https://openalex.org/keywords/nicotinamide-streptozotocin-induced-diabetes","display_name":"streptozotocin-nicotinamide-induced diabetes","score":0.8410000205039978},{"id":"https://openalex.org/keywords/nanoformulations","display_name":"nanoformulations","score":0.7289999723434448}],"concepts":[{"id":"https://openalex.org/C2778250585","wikidata":"https://www.wikidata.org/wiki/Q312266","display_name":"Curcumin","level":2,"score":0.9534472823143005},{"id":"https://openalex.org/C2777391703","wikidata":"https://www.wikidata.org/wiki/Q1053470","display_name":"Insulin resistance","level":3,"score":0.7723376750946045},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.7192856073379517},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.6700147986412048},{"id":"https://openalex.org/C2779280383","wikidata":"https://www.wikidata.org/wiki/Q257331","display_name":"Streptozotocin","level":3,"score":0.574583113193512},{"id":"https://openalex.org/C2779546753","wikidata":"https://www.wikidata.org/wiki/Q2386988","display_name":"Apelin","level":3,"score":0.5739559531211853},{"id":"https://openalex.org/C2779306644","wikidata":"https://www.wikidata.org/wiki/Q2002370","display_name":"Insulin","level":2,"score":0.5297043323516846},{"id":"https://openalex.org/C2778913445","wikidata":"https://www.wikidata.org/wiki/Q186319","display_name":"Triglyceride","level":3,"score":0.507890522480011},{"id":"https://openalex.org/C2910068830","wikidata":"https://www.wikidata.org/wiki/Q3025883","display_name":"Type 2 Diabetes Mellitus","level":3,"score":0.49627023935317993},{"id":"https://openalex.org/C2778270857","wikidata":"https://www.wikidata.org/wiki/Q2723972","display_name":"Lipid profile","level":3,"score":0.48805153369903564},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.4541685879230499},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4522153437137604},{"id":"https://openalex.org/C8243546","wikidata":"https://www.wikidata.org/wiki/Q419074","display_name":"Very low-density lipoprotein","level":4,"score":0.41556161642074585},{"id":"https://openalex.org/C2778163477","wikidata":"https://www.wikidata.org/wiki/Q43656","display_name":"Cholesterol","level":2,"score":0.36323344707489014},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3208703398704529},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.2724990248680115},{"id":"https://openalex.org/C2780072125","wikidata":"https://www.wikidata.org/wiki/Q28350","display_name":"Lipoprotein","level":3,"score":0.18942385911941528},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.03990417718887329}],"mesh":[],"locations_count":5,"locations":[{"id":"doi:10.2147/dmso.s247351","doi":"https://doi.org/10.2147/dmso.s247351","is_oa":true,"landing_page_url":"https://doi.org/10.2147/dmso.s247351","pdf_url":"https://www.dovepress.com/getfile.php?fileID=59406","source":{"id":"https://openalex.org/S176615914","display_name":"Diabetes Metabolic Syndrome and Obesity","issn_l":"1178-7007","issn":["1178-7007"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","doyens","jufo-1","ki-jl-1","norway-1","oarl","poland-100","russia-white-list-3","vabb-shw"],"host_organization":"https://openalex.org/P4310320348","host_organization_name":"Dove Medical Press","host_organization_lineage":["https://openalex.org/P4310320348","https://openalex.org/P4310320547"],"host_organization_lineage_names":["Dove Medical Press","Taylor & Francis"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy","raw_type":"journal-article"},{"id":"pmid:32753918","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/32753918","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Diabetes, metabolic syndrome and obesity : targets and therapy","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:7342486","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC7342486/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Diabetes Metab Syndr Obes","raw_type":"Text"},{"id":"pmh:oai:doaj.org/article:9a1c0b194ffd4828b6dca77ea6119646","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/9a1c0b194ffd4828b6dca77ea6119646","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Diabetes, Metabolic Syndrome and Obesity, Vol Volume 13, Pp 2337-2346 (2020)","raw_type":"article"},{"id":"pmh:oai:dovepress.com/55052","doi":null,"is_oa":true,"landing_page_url":"https://www.dovepress.com/comparative-effects-of-curcumin-versus-nano-curcumin-on-insulin-resist-peer-reviewed-article-DMSO","pdf_url":null,"source":{"id":"https://openalex.org/S4306401012","display_name":"Dove Medical Press (Taylor and Francis Group)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.2147/dmso.s247351","doi":"https://doi.org/10.2147/dmso.s247351","is_oa":true,"landing_page_url":"https://doi.org/10.2147/dmso.s247351","pdf_url":"https://www.dovepress.com/getfile.php?fileID=59406","source":{"id":"https://openalex.org/S176615914","display_name":"Diabetes Metabolic Syndrome and Obesity","issn_l":"1178-7007","issn":["1178-7007"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","doyens","jufo-1","ki-jl-1","norway-1","oarl","poland-100","russia-white-list-3","vabb-shw"],"host_organization":"https://openalex.org/P4310320348","host_organization_name":"Dove Medical Press","host_organization_lineage":["https://openalex.org/P4310320348","https://openalex.org/P4310320547"],"host_organization_lineage_names":["Dove Medical Press","Taylor & Francis"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":1.0}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320322936","display_name":"Zahedan University of Medical Sciences","ror":"https://ror.org/02n43xw86"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3039748972.pdf","grobid_xml":"https://content.openalex.org/works/W3039748972.grobid-xml"},"referenced_works_count":49,"referenced_works":["https://openalex.org/W62030978","https://openalex.org/W1026598425","https://openalex.org/W1500268075","https://openalex.org/W1566675140","https://openalex.org/W1965659213","https://openalex.org/W1966508121","https://openalex.org/W1970860759","https://openalex.org/W1972230767","https://openalex.org/W1975591344","https://openalex.org/W1976699663","https://openalex.org/W1981894034","https://openalex.org/W1982563578","https://openalex.org/W1986117957","https://openalex.org/W1991327193","https://openalex.org/W2008589619","https://openalex.org/W2012037560","https://openalex.org/W2013302181","https://openalex.org/W2017451930","https://openalex.org/W2036373988","https://openalex.org/W2055785991","https://openalex.org/W2061031670","https://openalex.org/W2066020267","https://openalex.org/W2075714512","https://openalex.org/W2076475060","https://openalex.org/W2078554361","https://openalex.org/W2082225136","https://openalex.org/W2096979174","https://openalex.org/W2108250096","https://openalex.org/W2112492104","https://openalex.org/W2132257581","https://openalex.org/W2142914294","https://openalex.org/W2145826667","https://openalex.org/W2149026746","https://openalex.org/W2168323414","https://openalex.org/W2339666534","https://openalex.org/W2371616861","https://openalex.org/W2397396704","https://openalex.org/W2478293489","https://openalex.org/W2509220708","https://openalex.org/W2511287076","https://openalex.org/W2521775360","https://openalex.org/W2606328821","https://openalex.org/W2621169164","https://openalex.org/W2767370465","https://openalex.org/W2792098929","https://openalex.org/W2809350139","https://openalex.org/W2930171697","https://openalex.org/W2941752216","https://openalex.org/W2975799677"],"related_works":["https://openalex.org/W4412853496","https://openalex.org/W4405105232","https://openalex.org/W4390522570","https://openalex.org/W6963959820","https://openalex.org/W3138027508","https://openalex.org/W4399220209","https://openalex.org/W2965890884","https://openalex.org/W7164163054","https://openalex.org/W3019459614","https://openalex.org/W2763320334"],"abstract_inverted_index":{"BACKGROUND":[0],"AND":[1,71],"PURPOSE:":[2],"Type":[3],"2":[4],"diabetes":[5],"mellitus":[6],"(T2DM)":[7],"is":[8,19,194],"characterized":[9],"by":[10,112,135],"insulin":[11,16,22,47,148,219,239],"resistance":[12,48,149,163],"and":[13,43,49,58,65,92,95,104,119,133,150,156,164,173,184,212,233,246],"abnormalities":[14],"in":[15,67,123,178,190,204,237,258],"production.":[17],"Apelin":[18],"associated":[20],"with":[21,86,98,182,217],"resistance.":[23],"According":[24],"to":[25,37],"the":[26,31,39,124,142,145],"anti-diabetic":[27],"properties":[28],"of":[29,33,41,52,89,101,108,115,131,144,153,167,202,223,231,243,251],"curcumin,":[30],"purpose":[32],"this":[34],"study":[35],"was":[36,110,207,255],"compare":[38],"effects":[40,230],"curcumin":[42,90,134,183,198,213,232],"nano-curcumin":[44,102,132,185,189,205,234,254],"intake":[45],"on":[46],"serum":[50,151,165,221,241],"levels":[51,152,166,242],"fasting":[53,125],"blood":[54],"sugar":[55],"(FBS),":[56],"Apelin,":[57,169],"lipid":[59,157,192,247,260],"profile":[60,193],"(cholesterol,":[61],"triglyceride,":[62],"LDL,":[63,172],"HDL":[64,203],"VLDL)":[66],"T2DM":[68,109],"rats.":[69],"MATERIALS":[70],"METHODS:":[72],"Forty-eight":[73],"male":[74],"Wistar":[75],"rats":[76,180],"were":[77,159,175,235],"divided":[78],"into":[79],"six":[80],"groups:":[81],"Control,":[82],"diabetic,":[83],"diabetic":[84,96,179,211],"treated":[85,97,181],"two":[87,99],"doses":[88,100,130],"(100":[91,103],"200":[93,105],"mg/kg)":[94,118,122],"mg/kg).":[106],"Induction":[107],"performed":[111],"intraperitoneal":[113],"injection":[114],"Nicotinamide":[116],"(110":[117],"Streptozotocin":[120],"(45":[121],"state.":[126],"Rats":[127],"received":[128],"different":[129],"gavage":[136],"(daily)":[137],"for":[138],"28":[139],"days.":[140],"At":[141],"end":[143],"intervention":[146],"period,":[147],"FBS,":[154,168,244],"apelin":[155,224,245],"profiles":[158],"measured.":[160],"RESULTS:":[161],"Insulin":[162],"cholesterol,":[170],"triglycerides,":[171],"VLDL":[174],"significantly":[176,208],"decreased":[177],"(p<0.05)":[186],"so":[187],"that":[188],"reducing":[191,259],"more":[195,256],"effective":[196,236,257],"than":[197,210],"(P<0.05).":[199,226],"Serum":[200],"level":[201,222],"groups":[206,214],"higher":[209],"(p<0.05).":[215],"Also,":[216],"increasing":[218],"resistance,":[220,240],"increased":[225],"CONCLUSION:":[227],"The":[228,249],"therapeutic":[229],"decreasing":[238],"profile.":[248,261],"dose":[250],"100":[252],"mg/kg":[253]},"counts_by_year":[{"year":2026,"cited_by_count":12},{"year":2025,"cited_by_count":10},{"year":2024,"cited_by_count":11},{"year":2023,"cited_by_count":10},{"year":2022,"cited_by_count":9},{"year":2021,"cited_by_count":11},{"year":2020,"cited_by_count":1}],"updated_date":"2026-11-12T12:28:57.059296","created_date":"2020-07-10T00:00:00"}
