{"id":"https://openalex.org/W3037726163","doi":"https://doi.org/10.1111/ejh.13477","title":"A population\u2010based study on serious inpatient bacterial infections in patients with chronic lymphocytic leukemia and their impact on survival","display_name":"A population\u2010based study on serious inpatient bacterial infections in patients with chronic lymphocytic leukemia and their impact on survival","publication_year":2020,"publication_date":"2020-06-23","ids":{"openalex":"https://openalex.org/W3037726163","doi":"https://doi.org/10.1111/ejh.13477","mag":"3037726163","pmid":"https://pubmed.ncbi.nlm.nih.gov/32575150"},"language":"en","primary_location":{"id":"doi:10.1111/ejh.13477","doi":"https://doi.org/10.1111/ejh.13477","is_oa":false,"landing_page_url":"https://doi.org/10.1111/ejh.13477","pdf_url":null,"source":{"id":"https://openalex.org/S159715054","display_name":"European Journal Of Haematology","issn_l":"0902-4441","issn":["0902-4441","1600-0609"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European Journal of Haematology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5040341889","display_name":"Vilhj\u00e1lmur Steingr\u00edmsson","orcid":"https://orcid.org/0000-0002-9385-2960","observed_orcids":["https://orcid.org/0000-0002-9385-2960"]},"institutions":[{"id":"https://openalex.org/I165368041","display_name":"University of Iceland","ror":"https://ror.org/01db6h964","country_code":"IS","type":"education","lineage":["https://openalex.org/I165368041"]}],"countries":["IS"],"is_corresponding":true,"raw_author_name":"Vilhj\u00e1lmur Steingr\u00edmsson","raw_affiliation_strings":["Faculty of Medicine University of Iceland Reykjavik Iceland"],"raw_orcid":"https://orcid.org/0000-0002-9385-2960","affiliations":[{"raw_affiliation_string":"Faculty of Medicine University of Iceland Reykjavik Iceland","institution_ids":["https://openalex.org/I165368041"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Gauti K. G\u00edslason","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I165368041","display_name":"University of Iceland","ror":"https://ror.org/01db6h964","country_code":"IS","type":"education","lineage":["https://openalex.org/I165368041"]}],"countries":["IS"],"is_corresponding":false,"raw_author_name":"Gauti K. G\u00edslason","raw_affiliation_strings":["Faculty of Medicine University of Iceland Reykjavik Iceland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Medicine University of Iceland Reykjavik Iceland","institution_ids":["https://openalex.org/I165368041"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072295805","display_name":"Thor Aspelund","orcid":"https://orcid.org/0000-0002-7998-5433","observed_orcids":["https://orcid.org/0000-0002-7998-5433"]},"institutions":[{"id":"https://openalex.org/I165368041","display_name":"University of Iceland","ror":"https://ror.org/01db6h964","country_code":"IS","type":"education","lineage":["https://openalex.org/I165368041"]}],"countries":["IS"],"is_corresponding":false,"raw_author_name":"Thor Aspelund","raw_affiliation_strings":["Centre for Public Health Sciences University of Iceland Reykjavik Iceland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre for Public Health Sciences University of Iceland Reykjavik Iceland","institution_ids":["https://openalex.org/I165368041"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029832651","display_name":"Ingemar Turesson","orcid":"https://orcid.org/0000-0002-4115-8010","observed_orcids":["https://orcid.org/0000-0002-4115-8010"]},"institutions":[{"id":"https://openalex.org/I4210137844","display_name":"Sk\u00e5ne University Hospital","ror":"https://ror.org/02z31g829","country_code":"SE","type":"healthcare","lineage":["https://openalex.org/I4210137844"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Ingemar Turesson","raw_affiliation_strings":["Department of Hematology and Coagulation Disorders Skane University Hospital Malm\u00f6 Sweden"],"raw_orcid":"https://orcid.org/0000-0002-4115-8010","affiliations":[{"raw_affiliation_string":"Department of Hematology and Coagulation Disorders Skane University Hospital Malm\u00f6 Sweden","institution_ids":["https://openalex.org/I4210137844"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046644939","display_name":"Magnus Bj\u00f6rkholm","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1335113835","display_name":"Karolinska University Hospital","ror":"https://ror.org/00m8d6786","country_code":"SE","type":"healthcare","lineage":["https://openalex.org/I1335113835"]},{"id":"https://openalex.org/I28166907","display_name":"Karolinska Institutet","ror":"https://ror.org/056d84691","country_code":"SE","type":"education","lineage":["https://openalex.org/I28166907"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Magnus Bj\u00f6rkholm","raw_affiliation_strings":["Department of Medicine Karolinska University Hospital and Karolinska Institutet Stockholm Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine Karolinska University Hospital and Karolinska Institutet Stockholm Sweden","institution_ids":["https://openalex.org/I1335113835","https://openalex.org/I28166907"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082004555","display_name":"Ola Landgren","orcid":"https://orcid.org/0000-0001-6485-4839","observed_orcids":["https://orcid.org/0000-0001-6485-4839"]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ola Landgren","raw_affiliation_strings":["Myeloma Service Memorial Sloan\u2010Kettering Cancer Center New York NY USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Myeloma Service Memorial Sloan\u2010Kettering Cancer Center New York NY USA","institution_ids":["https://openalex.org/I1334819555"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5001522697","display_name":"Sigurdur Yngvi Kristinsson","orcid":"https://orcid.org/0000-0002-4964-7476","observed_orcids":["https://orcid.org/0000-0002-4964-7476"]},"institutions":[{"id":"https://openalex.org/I1335113835","display_name":"Karolinska University Hospital","ror":"https://ror.org/00m8d6786","country_code":"SE","type":"healthcare","lineage":["https://openalex.org/I1335113835"]},{"id":"https://openalex.org/I165368041","display_name":"University of Iceland","ror":"https://ror.org/01db6h964","country_code":"IS","type":"education","lineage":["https://openalex.org/I165368041"]},{"id":"https://openalex.org/I28166907","display_name":"Karolinska Institutet","ror":"https://ror.org/056d84691","country_code":"SE","type":"education","lineage":["https://openalex.org/I28166907"]}],"countries":["IS","SE"],"is_corresponding":false,"raw_author_name":"Sigurdur Y. Kristinsson","raw_affiliation_strings":["Department of Medicine Karolinska University Hospital and Karolinska Institutet Stockholm Sweden","Faculty of Medicine University of Iceland Reykjavik Iceland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine Karolinska University Hospital and Karolinska Institutet Stockholm Sweden","institution_ids":["https://openalex.org/I1335113835","https://openalex.org/I28166907"]},{"raw_affiliation_string":"Faculty of Medicine University of Iceland Reykjavik Iceland","institution_ids":["https://openalex.org/I165368041"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5040341889"],"corresponding_institution_ids":["https://openalex.org/I165368041"],"apc_list":{"value":3400,"currency":"USD","value_usd":3400},"apc_paid":null,"fwci":0.1294,"has_fulltext":false,"cited_by_count":5,"citation_normalized_percentile":{"value":0.43614705,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"105","issue":"5","first_page":"547","last_page":"554"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11157","display_name":"Chronic Lymphocytic Leukemia Research","score":0.9965999722480774,"subfield":{"id":"https://openalex.org/subfields/2716","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11157","display_name":"Chronic Lymphocytic Leukemia Research","score":0.9965999722480774,"subfield":{"id":"https://openalex.org/subfields/2716","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12172","display_name":"Neutropenia and Cancer Infections","score":0.002199999988079071,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11725","display_name":"Immunodeficiency and Autoimmune Disorders","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/chronic-lymphocytic-leukemia","display_name":"chronic lymphocytic leukemia","score":1.0},{"id":"https://openalex.org/keywords/bacterial-infection","display_name":"bacterial infection","score":0.7850000262260437},{"id":"https://openalex.org/keywords/septicemia","display_name":"septicemia","score":0.8090000152587891},{"id":"https://openalex.org/keywords/pulmonary-infection","display_name":"pulmonary infection","score":0.8740000128746033},{"id":"https://openalex.org/keywords/inpatient-infections","display_name":"inpatient infections","score":0.8889999985694885},{"id":"https://openalex.org/keywords/real-world-data","display_name":"real-world data","score":0.5350000262260437}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8648207187652588},{"id":"https://openalex.org/C2777938653","wikidata":"https://www.wikidata.org/wiki/Q1088156","display_name":"Chronic lymphocytic leukemia","level":3,"score":0.7217922210693359},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6774165034294128},{"id":"https://openalex.org/C207103383","wikidata":"https://www.wikidata.org/wiki/Q3930246","display_name":"Hazard ratio","level":3,"score":0.6296095848083496},{"id":"https://openalex.org/C44249647","wikidata":"https://www.wikidata.org/wiki/Q208498","display_name":"Confidence interval","level":2,"score":0.5934808850288391},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.46076464653015137},{"id":"https://openalex.org/C2778461978","wikidata":"https://www.wikidata.org/wiki/Q29496","display_name":"Leukemia","level":2,"score":0.36081254482269287},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.07820284366607666}],"mesh":[{"descriptor_ui":"D001424","descriptor_name":"Bacterial Infections","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true},{"descriptor_ui":"D001424","descriptor_name":"Bacterial Infections","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":false},{"descriptor_ui":"D001424","descriptor_name":"Bacterial Infections","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":true},{"descriptor_ui":"D003428","descriptor_name":"Cross Infection","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":false},{"descriptor_ui":"D003428","descriptor_name":"Cross Infection","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":true},{"descriptor_ui":"D004198","descriptor_name":"Disease Susceptibility","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007297","descriptor_name":"Inpatients","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011379","descriptor_name":"Prognosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012307","descriptor_name":"Risk Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013548","descriptor_name":"Sweden","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D015451","descriptor_name":"Leukemia, Lymphocytic, Chronic, B-Cell","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D015451","descriptor_name":"Leukemia, Lymphocytic, Chronic, B-Cell","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":true},{"descriptor_ui":"D018570","descriptor_name":"Risk Assessment","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D062486","descriptor_name":"Public Health Surveillance","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1111/ejh.13477","doi":"https://doi.org/10.1111/ejh.13477","is_oa":false,"landing_page_url":"https://doi.org/10.1111/ejh.13477","pdf_url":null,"source":{"id":"https://openalex.org/S159715054","display_name":"European Journal Of Haematology","issn_l":"0902-4441","issn":["0902-4441","1600-0609"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European Journal of Haematology","raw_type":"journal-article"},{"id":"pmid:32575150","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/32575150","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European journal of haematology","raw_type":"Journal Article"},{"id":"pmh:oai:lup.lub.lu.se:69d2eed4-c836-43bf-86a2-0822a4692a8b","doi":null,"is_oa":false,"landing_page_url":"https://lup.lub.lu.se/record/69d2eed4-c836-43bf-86a2-0822a4692a8b","pdf_url":null,"source":{"id":"https://openalex.org/S4306400536","display_name":"Lund University Publications (Lund University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I187531555","host_organization_name":"Lund University","host_organization_lineage":["https://openalex.org/I187531555"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"European Journal of Haematology; (2020)","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":1.0,"display_name":"Good health and well-being"}],"sustainable_development_goals_aurora":[{"id":"https://metadata.un.org/sdg/3","score":0.5799999833106995,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[{"id":"https://openalex.org/G9000856728","display_name":"Cancer Center Support Grant","funder_award_id":"P30CA008748","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"}],"funders":[{"id":"https://openalex.org/F4320306439","display_name":"Multiple Myeloma Research Foundation","ror":"https://ror.org/03ww1bx13"},{"id":"https://openalex.org/F4320307105","display_name":"Amgen","ror":"https://ror.org/03g03ge92"},{"id":"https://openalex.org/F4320307607","display_name":"International Myeloma Foundation","ror":"https://ror.org/05qmfyw56"},{"id":"https://openalex.org/F4320308295","display_name":"Leukemia and Lymphoma Society","ror":"https://ror.org/04m0xav37"},{"id":"https://openalex.org/F4320309086","display_name":"Celgene","ror":"https://ror.org/0527yg379"},{"id":"https://openalex.org/F4320311929","display_name":"Seattle Genetics","ror":"https://ror.org/01vwesc15"},{"id":"https://openalex.org/F4320319417","display_name":"Glenmark Pharmaceuticals","ror":"https://ror.org/037fhg487"},{"id":"https://openalex.org/F4320321491","display_name":"Cancerfonden","ror":"https://ror.org/0527jb766"},{"id":"https://openalex.org/F4320326825","display_name":"Rann\u00eds","ror":null},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"},{"id":"https://openalex.org/F4320337449","display_name":"Janssen Biotech","ror":"https://ror.org/03qd7mz70"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":31,"referenced_works":["https://openalex.org/W1576885319","https://openalex.org/W1891620832","https://openalex.org/W1984412456","https://openalex.org/W1986535649","https://openalex.org/W2012234169","https://openalex.org/W2015120596","https://openalex.org/W2027802134","https://openalex.org/W2057686471","https://openalex.org/W2070193300","https://openalex.org/W2084433218","https://openalex.org/W2089344948","https://openalex.org/W2102630933","https://openalex.org/W2108726442","https://openalex.org/W2136784933","https://openalex.org/W2150044749","https://openalex.org/W2153230055","https://openalex.org/W2160782995","https://openalex.org/W2161926682","https://openalex.org/W2166018731","https://openalex.org/W2310252982","https://openalex.org/W2326175431","https://openalex.org/W2556967777","https://openalex.org/W2563529755","https://openalex.org/W2735193038","https://openalex.org/W2753152241","https://openalex.org/W2770618238","https://openalex.org/W2793465190","https://openalex.org/W2811404995","https://openalex.org/W2904951656","https://openalex.org/W2998886612","https://openalex.org/W3146478735"],"related_works":["https://openalex.org/W2964961497","https://openalex.org/W2413909440","https://openalex.org/W2310252982","https://openalex.org/W3104557984","https://openalex.org/W7204696628","https://openalex.org/W2592454760","https://openalex.org/W2904951656","https://openalex.org/W1985243817","https://openalex.org/W2410226932","https://openalex.org/W2593810118"],"abstract_inverted_index":{"OBJECTIVE:":[0],"Infections":[1],"in":[2,11,43,56,127,159,175,186],"chronic":[3],"lymphocytic":[4],"leukemia":[5],"(CLL)":[6],"have":[7],"been":[8],"thoroughly":[9],"investigated":[10],"the":[12,93,155,160,165,180,193],"setting":[13],"of":[14,74,112,141,182],"clinical":[15],"trials":[16],"and":[17,27,58,85,92,105,123,129,154],"single-center":[18],"studies.":[19],"However,":[20],"large":[21],"cohort":[22],"studies":[23,28],"on":[24,29,39],"real-world":[25],"data":[26],"temporal":[30],"trends":[31],"are":[32],"lacking.":[33],"We":[34,173],"performed":[35],"a":[36,80,144],"nationwide":[37,177],"study":[38],"serious":[40,75,113,145,183],"bacterial":[41,77,115,147,184],"infections":[42,78,107,116,185],"CLL.":[44],"METHODS:":[45],"Using":[46],"high-quality":[47],"Swedish":[48],"government-based":[49],"registries,":[50],"13":[51],"009":[52],"CLL":[53,68,135,152,187],"patients":[54,69,136,188],"diagnosed":[55],"1982-2013":[57],"their":[59],"49":[60],"380":[61],"matched":[62,151],"controls":[63],"were":[64],"included.":[65],"RESULTS:":[66],"Overall,":[67],"had":[70,137],"an":[71,138],"increased":[72,139],"risk":[73,95,111,140,156,181,194],"inpatient":[76,114,146],"with":[79,119],"hazard":[81],"ratio":[82],"(HR)":[83],"5.32":[84],"95%":[86,102,169],"confidence":[87],"interval":[88],"(95%":[89],"CI)":[90],"5.11-5.53,":[91],"highest":[94,158],"was":[96,157],"observed":[97],"for":[98],"septicemia":[99],"(HR":[100,167],"6.91,":[101],"CI":[103,170],"6.46-7.39)":[104],"lung":[106],"(5.91,":[108],"5.64-6.18).":[109],"The":[110],"decreased":[117,196],"overtime":[118],"HR":[120,124],"0.87":[121],"(0.81-0.94)":[122],"0.76":[125],"(0.70-0.82)":[126],"1993-2002":[128],"2003-2013,":[130],"respectively,":[131],"compared":[132,149],"to":[133,150],"1982-1992.":[134],"death":[142],"following":[143],"infection":[148,166],"patients,":[153],"first":[161],"12":[162],"months":[163],"after":[164],"5.48,":[168],"5.11-5.90).":[171],"CONCLUSION:":[172],"have,":[174],"this":[176],"study,":[178],"characterized":[179],"and,":[189],"importantly,":[190],"depicted":[191],"that":[192],"has":[195],"overtime.":[197]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":2},{"year":2021,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2020-07-02T00:00:00"}