{"id":"https://openalex.org/W3037102000","doi":"https://doi.org/10.3389/fimmu.2020.01623","title":"Potential Fast COVID-19 Containment With Trehalose","display_name":"Potential Fast COVID-19 Containment With Trehalose","publication_year":2020,"publication_date":"2020-07-07","ids":{"openalex":"https://openalex.org/W3037102000","doi":"https://doi.org/10.3389/fimmu.2020.01623","mag":"3037102000","pmid":"https://pubmed.ncbi.nlm.nih.gov/32733488","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/7358456"},"language":"en","primary_location":{"id":"doi:10.3389/fimmu.2020.01623","doi":"https://doi.org/10.3389/fimmu.2020.01623","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fimmu.2020.01623","pdf_url":"https://www.frontiersin.org/articles/10.3389/fimmu.2020.01623/pdf","source":{"id":"https://openalex.org/S2595292759","display_name":"Frontiers in Immunology","issn_l":"1664-3224","issn":["1664-3224"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Immunology","raw_type":"journal-article"},"volume":null,"type":"review","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.frontiersin.org/articles/10.3389/fimmu.2020.01623/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5077034069","display_name":"Daisy Martinon","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1282927834","display_name":"Cedars-Sinai Medical Center","ror":"https://ror.org/02pammg90","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1282927834"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Daisy Martinon","raw_affiliation_strings":["Division of Infectious Diseases and Immunology, Department of Pediatrics, Cedars-Sinai Medical Center, Los Angeles, CA, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Infectious Diseases and Immunology, Department of Pediatrics, Cedars-Sinai Medical Center, Los Angeles, CA, United States","institution_ids":["https://openalex.org/I1282927834"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103910162","display_name":"Vanessa Borges","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1282927834","display_name":"Cedars-Sinai Medical Center","ror":"https://ror.org/02pammg90","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1282927834"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Vanessa F. Borges","raw_affiliation_strings":["Division of Infectious Diseases and Immunology, Department of Pediatrics, Cedars-Sinai Medical Center, Los Angeles, CA, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Infectious Diseases and Immunology, Department of Pediatrics, Cedars-Sinai Medical Center, Los Angeles, CA, United States","institution_ids":["https://openalex.org/I1282927834"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089111801","display_name":"Angela C. Gomez","orcid":"https://orcid.org/0000-0001-7019-9607","observed_orcids":["https://orcid.org/0000-0001-7019-9607"]},"institutions":[{"id":"https://openalex.org/I1282927834","display_name":"Cedars-Sinai Medical Center","ror":"https://ror.org/02pammg90","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1282927834"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Angela C. Gomez","raw_affiliation_strings":["Division of Infectious Diseases and Immunology, Department of Pediatrics, Cedars-Sinai Medical Center, Los Angeles, CA, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Infectious Diseases and Immunology, Department of Pediatrics, Cedars-Sinai Medical Center, Los Angeles, CA, United States","institution_ids":["https://openalex.org/I1282927834"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5101724127","display_name":"Kenichi Shimada","orcid":"https://orcid.org/0000-0001-8213-5686","observed_orcids":["https://orcid.org/0000-0001-8213-5686"]},"institutions":[{"id":"https://openalex.org/I1282927834","display_name":"Cedars-Sinai Medical Center","ror":"https://ror.org/02pammg90","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1282927834"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Kenichi Shimada","raw_affiliation_strings":["Department of Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, CA, United States","Division of Infectious Diseases and Immunology, Department of Pediatrics, Cedars-Sinai Medical Center, Los Angeles, CA, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, CA, United States","institution_ids":["https://openalex.org/I1282927834"]},{"raw_affiliation_string":"Division of Infectious Diseases and Immunology, Department of Pediatrics, Cedars-Sinai Medical Center, Los Angeles, CA, United States","institution_ids":["https://openalex.org/I1282927834"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5101724127"],"corresponding_institution_ids":["https://openalex.org/I1282927834"],"apc_list":{"value":2950,"currency":"USD","value_usd":2950},"apc_paid":{"value":2950,"currency":"USD","value_usd":2950},"fwci":0.1892,"has_fulltext":true,"cited_by_count":23,"citation_normalized_percentile":{"value":0.38263716,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":93,"max":98},"biblio":{"volume":"11","issue":null,"first_page":"1623","last_page":"1623"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10118","display_name":"SARS-CoV-2 and COVID-19 Research","score":0.9740999937057495,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10118","display_name":"SARS-CoV-2 and COVID-19 Research","score":0.9740999937057495,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10041","display_name":"COVID-19 Clinical Research Studies","score":0.020099999383091927,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10410","display_name":"COVID-19 epidemiological studies","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/2611","display_name":"Modeling and Simulation"},"field":{"id":"https://openalex.org/fields/26","display_name":"Mathematics"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/trehalose","display_name":"trehalose","score":0.9959999918937683},{"id":"https://openalex.org/keywords/covid-19","display_name":"COVID-19 pandemic","score":0.9589999914169312},{"id":"https://openalex.org/keywords/sars-cov-2","display_name":"SARS-CoV-2","score":0.9980000257492065},{"id":"https://openalex.org/keywords/autophagy","display_name":"autophagy","score":0.7699999809265137},{"id":"https://openalex.org/keywords/antiviral-therapy","display_name":"antiviral therapy","score":0.753000020980835},{"id":"https://openalex.org/keywords/prevention","display_name":"prevention","score":0.3790000081062317},{"id":"https://openalex.org/keywords/virus-transmission","display_name":"virus transmission","score":0.367000013589859},{"id":"https://openalex.org/keywords/low-resource-countries","display_name":"resource-poor countries","score":0.6690000295639038},{"id":"https://openalex.org/keywords/healthcare-workers","display_name":"healthcare workers","score":0.640999972820282}],"concepts":[{"id":"https://openalex.org/C2778452849","wikidata":"https://www.wikidata.org/wiki/Q421773","display_name":"Trehalose","level":2,"score":0.789548397064209},{"id":"https://openalex.org/C3008058167","wikidata":"https://www.wikidata.org/wiki/Q84263196","display_name":"Coronavirus disease 2019 (COVID-19)","level":4,"score":0.6600756645202637},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.5288613438606262},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5203511118888855},{"id":"https://openalex.org/C2988170871","wikidata":"https://www.wikidata.org/wiki/Q11000047","display_name":"Healthcare system","level":3,"score":0.5009949207305908},{"id":"https://openalex.org/C3007834351","wikidata":"https://www.wikidata.org/wiki/Q82069695","display_name":"Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)","level":5,"score":0.4788767695426941},{"id":"https://openalex.org/C761482","wikidata":"https://www.wikidata.org/wiki/Q118093","display_name":"Transmission (telecommunications)","level":2,"score":0.4608857333660126},{"id":"https://openalex.org/C160735492","wikidata":"https://www.wikidata.org/wiki/Q31207","display_name":"Health care","level":2,"score":0.4571632146835327},{"id":"https://openalex.org/C46578552","wikidata":"https://www.wikidata.org/wiki/Q2725393","display_name":"Global health","level":3,"score":0.45549190044403076},{"id":"https://openalex.org/C138816342","wikidata":"https://www.wikidata.org/wiki/Q189603","display_name":"Public health","level":2,"score":0.3707551956176758},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.24470707774162292},{"id":"https://openalex.org/C524204448","wikidata":"https://www.wikidata.org/wiki/Q788926","display_name":"Infectious disease (medical specialty)","level":3,"score":0.2245185375213623},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.20035073161125183},{"id":"https://openalex.org/C50522688","wikidata":"https://www.wikidata.org/wiki/Q189833","display_name":"Economic growth","level":1,"score":0.17619270086288452},{"id":"https://openalex.org/C159110408","wikidata":"https://www.wikidata.org/wiki/Q121176","display_name":"Nursing","level":1,"score":0.10703667998313904},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.10596159100532532},{"id":"https://openalex.org/C162324750","wikidata":"https://www.wikidata.org/wiki/Q8134","display_name":"Economics","level":0,"score":0.08810833096504211},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.08344554901123047},{"id":"https://openalex.org/C76155785","wikidata":"https://www.wikidata.org/wiki/Q418","display_name":"Telecommunications","level":1,"score":0.0},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000073640","descriptor_name":"Betacoronavirus","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D000086382","descriptor_name":"COVID-19","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000086402","descriptor_name":"SARS-CoV-2","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000093485","descriptor_name":"COVID-19 Drug Treatment","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000998","descriptor_name":"Antiviral Agents","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D000998","descriptor_name":"Antiviral Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D001343","descriptor_name":"Autophagy","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D002648","descriptor_name":"Child","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011024","descriptor_name":"Pneumonia, Viral","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D011024","descriptor_name":"Pneumonia, Viral","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":false},{"descriptor_ui":"D011024","descriptor_name":"Pneumonia, Viral","qualifier_ui":"Q000635","qualifier_name":"transmission","is_major_topic":false},{"descriptor_ui":"D011024","descriptor_name":"Pneumonia, Viral","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":false},{"descriptor_ui":"D014199","descriptor_name":"Trehalose","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D014199","descriptor_name":"Trehalose","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D014779","descriptor_name":"Virus Replication","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D018352","descriptor_name":"Coronavirus Infections","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D018352","descriptor_name":"Coronavirus Infections","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":false},{"descriptor_ui":"D018352","descriptor_name":"Coronavirus Infections","qualifier_ui":"Q000635","qualifier_name":"transmission","is_major_topic":false},{"descriptor_ui":"D018352","descriptor_name":"Coronavirus Infections","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":false},{"descriptor_ui":"D056990","descriptor_name":"Post-Exposure Prophylaxis","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D058070","descriptor_name":"Asymptomatic Diseases","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D058873","descriptor_name":"Pandemics","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":false},{"descriptor_ui":"D065129","descriptor_name":"Pre-Exposure Prophylaxis","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.3389/fimmu.2020.01623","doi":"https://doi.org/10.3389/fimmu.2020.01623","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fimmu.2020.01623","pdf_url":"https://www.frontiersin.org/articles/10.3389/fimmu.2020.01623/pdf","source":{"id":"https://openalex.org/S2595292759","display_name":"Frontiers in Immunology","issn_l":"1664-3224","issn":["1664-3224"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Immunology","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:7358456","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/7358456","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Front Immunol","raw_type":"Text"},{"id":"pmid:32733488","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/32733488","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in immunology","raw_type":"Journal Article"},{"id":"pmh:oai:doaj.org/article:c4d94cd154bb46aa96256f90ee1f7daa","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/c4d94cd154bb46aa96256f90ee1f7daa","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Frontiers in Immunology, Vol 11 (2020)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.3389/fimmu.2020.01623","doi":"https://doi.org/10.3389/fimmu.2020.01623","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fimmu.2020.01623","pdf_url":"https://www.frontiersin.org/articles/10.3389/fimmu.2020.01623/pdf","source":{"id":"https://openalex.org/S2595292759","display_name":"Frontiers in Immunology","issn_l":"1664-3224","issn":["1664-3224"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Immunology","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9763000011444092,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320313996","display_name":"Cedars-Sinai Medical Center","ror":"https://ror.org/02pammg90"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3037102000.pdf","grobid_xml":"https://content.openalex.org/works/W3037102000.grobid-xml"},"referenced_works_count":97,"referenced_works":["https://openalex.org/W1578015828","https://openalex.org/W1580723613","https://openalex.org/W1965411122","https://openalex.org/W1966238900","https://openalex.org/W1969214131","https://openalex.org/W1977390016","https://openalex.org/W1979306731","https://openalex.org/W1983240538","https://openalex.org/W1985360059","https://openalex.org/W2002636911","https://openalex.org/W2012151421","https://openalex.org/W2014520750","https://openalex.org/W2021351468","https://openalex.org/W2030667534","https://openalex.org/W2033229501","https://openalex.org/W2043464646","https://openalex.org/W2046183696","https://openalex.org/W2059359876","https://openalex.org/W2075675534","https://openalex.org/W2077499130","https://openalex.org/W2105293460","https://openalex.org/W2106677353","https://openalex.org/W2119950877","https://openalex.org/W2122256368","https://openalex.org/W2130314757","https://openalex.org/W2148742147","https://openalex.org/W2154599034","https://openalex.org/W2155313245","https://openalex.org/W2163657665","https://openalex.org/W2199487085","https://openalex.org/W2284222432","https://openalex.org/W2286285703","https://openalex.org/W2461386074","https://openalex.org/W2513994159","https://openalex.org/W2539809602","https://openalex.org/W2575410421","https://openalex.org/W2580356750","https://openalex.org/W2587142564","https://openalex.org/W2587225611","https://openalex.org/W2593816418","https://openalex.org/W2610767031","https://openalex.org/W2622769153","https://openalex.org/W2725497285","https://openalex.org/W2735191646","https://openalex.org/W2774239504","https://openalex.org/W2777734899","https://openalex.org/W2781633877","https://openalex.org/W2802954507","https://openalex.org/W2808836146","https://openalex.org/W2810037075","https://openalex.org/W2900905513","https://openalex.org/W2902922365","https://openalex.org/W2903293690","https://openalex.org/W2904354111","https://openalex.org/W2912236790","https://openalex.org/W2922606230","https://openalex.org/W2935072569","https://openalex.org/W2953224333","https://openalex.org/W2953948138","https://openalex.org/W3001118548","https://openalex.org/W3005212621","https://openalex.org/W3005741104","https://openalex.org/W3006642361","https://openalex.org/W3006673111","https://openalex.org/W3008625900","https://openalex.org/W3009170734","https://openalex.org/W3009567932","https://openalex.org/W3010096538","https://openalex.org/W3010930696","https://openalex.org/W3011109778","https://openalex.org/W3011920985","https://openalex.org/W3012379316","https://openalex.org/W3012655019","https://openalex.org/W3012809680","https://openalex.org/W3013369257","https://openalex.org/W3013409232","https://openalex.org/W3013660050","https://openalex.org/W3014203610","https://openalex.org/W3014948915","https://openalex.org/W3015027564","https://openalex.org/W3015323620","https://openalex.org/W3015883707","https://openalex.org/W3015988827","https://openalex.org/W3016355278","https://openalex.org/W3016368675","https://openalex.org/W3017146689","https://openalex.org/W3018321317","https://openalex.org/W3018829510","https://openalex.org/W3020062806","https://openalex.org/W3020239101","https://openalex.org/W3021161367","https://openalex.org/W3022358203","https://openalex.org/W3022649823","https://openalex.org/W3023606094","https://openalex.org/W3025256562","https://openalex.org/W3032915827","https://openalex.org/W3121148838"],"related_works":["https://openalex.org/W3203279166","https://openalex.org/W4220942050","https://openalex.org/W7167579054","https://openalex.org/W4313470109","https://openalex.org/W3100731933","https://openalex.org/W3191305516","https://openalex.org/W3111486326","https://openalex.org/W2324530667","https://openalex.org/W3108417915","https://openalex.org/W3041792912"],"abstract_inverted_index":{"Countries":[0,86],"worldwide":[1,87],"have":[2],"confirmed":[3],"a":[4,41,89,117,136],"staggering":[5],"number":[6],"of":[7,34,82],"COVID-19":[8],"cases,":[9],"and":[10,37,96,143],"it":[11,105],"is":[12,18,65,75,106,121],"now":[13,39],"clear":[14],"that":[15],"no":[16],"country":[17],"immune":[19],"to":[20,55,61,68,92,123],"the":[21,56,80,94,98,101,113,128],"SARS-CoV-2":[22,141],"infection.":[23,49],"Resource-poor":[24],"countries":[25],"with":[26,32,45],"weaker":[27],"health":[28,102],"systems":[29],"are":[30,38,53],"struggling":[31],"epidemics":[33],"their":[35,59],"own":[36],"in":[40,58],"more":[42],"uncertain":[43,107],"situation":[44],"this":[46,109],"rapidly":[47],"spreading":[48],"Frontline":[50],"healthcare":[51],"workers":[52],"succumbing":[54],"infection":[57,142],"efforts":[60],"save":[62],"lives.":[63],"There":[64],"an":[66],"urgency":[67],"develop":[69],"treatments":[70],"for":[71,140],"COVID-19,":[72],"yet":[73],"there":[74],"limited":[76],"clinical":[77],"data":[78],"on":[79,100],"efficacy":[81],"potential":[83,137],"drug":[84],"treatments.":[85],"implemented":[88],"stay-at-home":[90],"order":[91],"\"flatten":[93],"curve\"":[95],"relieve":[97],"pressure":[99],"system,":[103],"but":[104],"how":[108],"will":[110],"unfold":[111],"after":[112],"economy":[114],"reopens.":[115],"Trehalose,":[116],"natural":[118],"glucose":[119],"disaccharide,":[120],"known":[122],"impair":[124],"viral":[125],"function":[126],"through":[127],"autophagy":[129],"system.":[130],"Here,":[131],"we":[132],"propose":[133],"trehalose":[134],"as":[135],"preventative":[138],"treatment":[139],"transmission.":[144]},"counts_by_year":[{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":5},{"year":2023,"cited_by_count":5},{"year":2022,"cited_by_count":5},{"year":2021,"cited_by_count":4},{"year":2020,"cited_by_count":2}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2020-07-02T00:00:00"}