{"id":"https://openalex.org/W3036932371","doi":"https://doi.org/10.1017/s0424820100098745","title":"SSB Protein\u2014Its Interaction with DNA and Use as a Tool in Studying Genome Structure","display_name":"SSB Protein\u2014Its Interaction with DNA and Use as a Tool in Studying Genome Structure","publication_year":1981,"publication_date":"1981-08-01","ids":{"openalex":"https://openalex.org/W3036932371","doi":"https://doi.org/10.1017/s0424820100098745","mag":"3036932371"},"language":"en","primary_location":{"id":"doi:10.1017/s0424820100098745","doi":"https://doi.org/10.1017/s0424820100098745","is_oa":false,"landing_page_url":"http://doi.org/10.1017/s0424820100098745","pdf_url":null,"source":{"id":"https://openalex.org/S4210239783","display_name":"Proceedings annual meeting Electron Microscopy Society of America","issn_l":"0424-8201","issn":["0424-8201","2690-1315"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310311721","host_organization_name":"Cambridge University Press","host_organization_lineage":["https://openalex.org/P4310311721","https://openalex.org/P4310311702"],"host_organization_lineage_names":["Cambridge University Press","University of Cambridge"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings, annual meeting, Electron Microscopy Society of America","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5065859514","display_name":"Susan Chrysegelos","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Susan Chrysegelos","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041220751","display_name":"Kathi Dunn","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Kathi Dunn","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061660001","display_name":"Jack D. Griffith","orcid":"https://orcid.org/0000-0002-8357-8689","observed_orcids":["https://orcid.org/0000-0002-8357-8689"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jack Griffith","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010835417","display_name":"Marcia Manning","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Marcia Manning","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5029319648","display_name":"Claire L. Moore","orcid":"https://orcid.org/0000-0002-1883-9459","observed_orcids":["https://orcid.org/0000-0002-1883-9459"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Claire Moore","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.35285466,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"39","issue":null,"first_page":"448","last_page":"451"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10120","display_name":"Bacterial Genetics and Biotechnology","score":0.45089998841285706,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10120","display_name":"Bacterial Genetics and Biotechnology","score":0.45089998841285706,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10432","display_name":"DNA and Nucleic Acid Chemistry","score":0.3352000117301941,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10123","display_name":"DNA Repair Mechanisms","score":0.09570000320672989,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/single-stranded-dna-binding-protein","display_name":"single-stranded DNA binding protein","score":0.9269999861717224},{"id":"https://openalex.org/keywords/sugar-sweetened-beverages","display_name":"sugar-sweetened beverages","score":0.7850000262260437},{"id":"https://openalex.org/keywords/protein-dna-interactions","display_name":"protein-DNA interactions","score":0.7409999966621399},{"id":"https://openalex.org/keywords/genome-structure","display_name":"genome structure","score":0.7020000219345093},{"id":"https://openalex.org/keywords/escherichia-coli","display_name":"Escherichia coli","score":0.7940000295639038},{"id":"https://openalex.org/keywords/cooperative-dna-binding","display_name":"cooperative DNA binding","score":0.6299999952316284},{"id":"https://openalex.org/keywords/nucleoprotein-complexes","display_name":"nucleoprotein complexes","score":0.6449999809265137},{"id":"https://openalex.org/keywords/quaternary-structure","display_name":"quaternary structure","score":0.718999981880188},{"id":"https://openalex.org/keywords/tetramer","display_name":"tetramer","score":0.4959999918937683}],"concepts":[{"id":"https://openalex.org/C77400797","wikidata":"https://www.wikidata.org/wiki/Q24724047","display_name":"Single-stranded binding protein","level":5,"score":0.7113369107246399},{"id":"https://openalex.org/C552990157","wikidata":"https://www.wikidata.org/wiki/Q7430","display_name":"DNA","level":2,"score":0.67823326587677},{"id":"https://openalex.org/C60325843","wikidata":"https://www.wikidata.org/wiki/Q419245","display_name":"Nucleoprotein","level":3,"score":0.6226043105125427},{"id":"https://openalex.org/C2778886173","wikidata":"https://www.wikidata.org/wiki/Q53832","display_name":"Tetramer","level":3,"score":0.5830415487289429},{"id":"https://openalex.org/C111921641","wikidata":"https://www.wikidata.org/wiki/Q80756","display_name":"Polynucleotide","level":2,"score":0.5438852310180664},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5065737962722778},{"id":"https://openalex.org/C547475151","wikidata":"https://www.wikidata.org/wiki/Q25419","display_name":"Escherichia coli","level":3,"score":0.45763495564460754},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.44431209564208984},{"id":"https://openalex.org/C67705224","wikidata":"https://www.wikidata.org/wiki/Q11053","display_name":"RNA","level":3,"score":0.42530521750450134},{"id":"https://openalex.org/C32010083","wikidata":"https://www.wikidata.org/wiki/Q2252764","display_name":"Protein\u2013DNA interaction","level":5,"score":0.41794878244400024},{"id":"https://openalex.org/C5179208","wikidata":"https://www.wikidata.org/wiki/Q3782057","display_name":"HMG-box","level":5,"score":0.4117043912410736},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.4047810733318329},{"id":"https://openalex.org/C94966510","wikidata":"https://www.wikidata.org/wiki/Q2252764","display_name":"DNA-binding protein","level":4,"score":0.3978666663169861},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.34022805094718933},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.33285510540008545},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.27394792437553406},{"id":"https://openalex.org/C86339819","wikidata":"https://www.wikidata.org/wiki/Q407384","display_name":"Transcription factor","level":3,"score":0.10381034016609192},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1017/s0424820100098745","doi":"https://doi.org/10.1017/s0424820100098745","is_oa":false,"landing_page_url":"http://doi.org/10.1017/s0424820100098745","pdf_url":null,"source":{"id":"https://openalex.org/S4210239783","display_name":"Proceedings annual meeting Electron Microscopy Society of America","issn_l":"0424-8201","issn":["0424-8201","2690-1315"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310311721","host_organization_name":"Cambridge University Press","host_organization_lineage":["https://openalex.org/P4310311721","https://openalex.org/P4310311702"],"host_organization_lineage_names":["Cambridge University Press","University of Cambridge"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings, annual meeting, Electron Microscopy Society of America","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":3,"referenced_works":["https://openalex.org/W2031342495","https://openalex.org/W2087518848","https://openalex.org/W2121813899"],"related_works":["https://openalex.org/W4248763847","https://openalex.org/W2794497310","https://openalex.org/W1924027056","https://openalex.org/W2153436893","https://openalex.org/W2185981906","https://openalex.org/W2051282470","https://openalex.org/W3132335929","https://openalex.org/W1806123628","https://openalex.org/W4319031842","https://openalex.org/W4398172278"],"abstract_inverted_index":{"A":[0],"protein":[1,41,52,135],"which":[2,162],"binds":[3],"tightly":[4,81],"to":[5,84,93,104,136,153,165],"single":[6,30,85,94,111],"stranded":[7,31,86,95,112],"DNA":[8,12,32,106],"but":[9],"not":[10],"duplex":[11,105],"was":[13],"first":[14],"isolated":[15],"from":[16,133],"Escherichia":[17],"coli":[18,46],"(E.":[19],"coli)":[20],"by":[21,76],"Sigal":[22],"et.":[23],"al":[24],"and":[25,48,82,97,138],"is":[26,163],"called":[27],"SSB":[28,37,149],"for":[29],"binding":[33,79,89,99,110,128],"protein.":[34],"Together":[35],"with":[36],"the":[38,49,59,64,73,167],"gene":[39,50],"32":[40],"of":[42,53,63,68,78,88,98,127,148],"T4":[43],"infected":[44,56],"E.":[45],"cells,":[47,57],"5":[51],"phage":[54],"M13":[55],"are":[58,130],"best":[60],"characterized":[61],"members":[62],"helix":[65],"destabilizing":[66],"family":[67],"proteins.":[69],"They":[70],"all":[71,103,117],"share":[72],"properties":[74],"(reviewed":[75],"Kbrnberg)":[77],"very":[80,131],"cooperatively":[83],"DNA,":[87],"somewhat":[90],"less":[91],"well":[92],"RNA,":[96],"poorly":[100],"if":[101],"at":[102],"or":[107],"RNA.":[108],"In":[109],"polynucleotides":[113],"these":[114],"proteins":[115],"disrupt":[116],"secondary":[118],"structure":[119],"yielding":[120],"a":[121,156],"linear":[122],"nucleoprotein":[123],"complex.":[124],"The":[125],"details":[126],"however":[129],"different":[132],"one":[134],"another":[137],"must":[139],"reflect":[140],"their":[141],"functional":[142],"roles":[143],"in":[144,160],"vivo.":[145],"Physical":[146],"studies":[147],"have":[150],"showi":[151],"it":[152],"exist":[154],"as":[155],"75,000":[157],"dalton":[158],"tetramer":[159],"solution":[161],"assumed":[164],"be":[166],"active":[168],"unit.":[169]},"counts_by_year":[],"updated_date":"2026-09-22T06:50:58.402377","created_date":"2020-06-25T00:00:00"}