{"id":"https://openalex.org/W3036924518","doi":"https://doi.org/10.1097/ypg.0000000000000258","title":"The effect of rs1076560 (DRD2) and rs4680 (COMT) on tardive dyskinesia and cognition in schizophrenia subjects","display_name":"The effect of rs1076560 (DRD2) and rs4680 (COMT) on tardive dyskinesia and cognition in schizophrenia subjects","publication_year":2020,"publication_date":"2020-06-18","ids":{"openalex":"https://openalex.org/W3036924518","doi":"https://doi.org/10.1097/ypg.0000000000000258","mag":"3036924518","pmid":"https://pubmed.ncbi.nlm.nih.gov/32931693","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/10111058"},"language":"en","primary_location":{"id":"doi:10.1097/ypg.0000000000000258","doi":"https://doi.org/10.1097/ypg.0000000000000258","is_oa":false,"landing_page_url":"https://doi.org/10.1097/ypg.0000000000000258","pdf_url":null,"source":{"id":"https://openalex.org/S41645954","display_name":"Psychiatric Genetics","issn_l":"0955-8829","issn":["0955-8829","1473-5873"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-3","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Psychiatric Genetics","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC10111058/pdf/nihms-1888627.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5041167097","display_name":"Toyanji Joseph Punchaichira","orcid":"https://orcid.org/0000-0001-5685-9808","observed_orcids":["https://orcid.org/0000-0001-5685-9808"]},"institutions":[{"id":"https://openalex.org/I110166357","display_name":"University of Delhi","ror":"https://ror.org/04gzb2213","country_code":"IN","type":"education","lineage":["https://openalex.org/I110166357"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Toyanji Joseph Punchaichira","raw_affiliation_strings":["Department of Genetics, University of Delhi South Campus, Benito Juarez Road"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Genetics, University of Delhi South Campus, Benito Juarez Road","institution_ids":["https://openalex.org/I110166357"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033810545","display_name":"Prachi Kukshal","orcid":"https://orcid.org/0000-0002-4695-9490","observed_orcids":["https://orcid.org/0000-0002-4695-9490"]},"institutions":[{"id":"https://openalex.org/I110166357","display_name":"University of Delhi","ror":"https://ror.org/04gzb2213","country_code":"IN","type":"education","lineage":["https://openalex.org/I110166357"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Prachi Kukshal","raw_affiliation_strings":["Department of Genetics, University of Delhi South Campus, Benito Juarez Road"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Genetics, University of Delhi South Campus, Benito Juarez Road","institution_ids":["https://openalex.org/I110166357"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044194974","display_name":"Triptish Bhatia A","orcid":"https://orcid.org/0000-0003-0544-9707","observed_orcids":["https://orcid.org/0000-0003-0544-9707"]},"institutions":[{"id":"https://openalex.org/I2800585909","display_name":"Atal Bihari Vajpayee Institute of Medical Sciences and Dr. Ram Manohar Lohia Hospital","ror":"https://ror.org/00qa63322","country_code":"IN","type":"funder","lineage":["https://openalex.org/I2800585909"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Triptish Bhatia","raw_affiliation_strings":["Department of Psychiatry, Postgraduate Institute of Medical Education and Research-Dr. Ram Manohar Lohia Hospital, Baba Kharak Singh Marg, Connaught Place, New Delhi, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychiatry, Postgraduate Institute of Medical Education and Research-Dr. Ram Manohar Lohia Hospital, Baba Kharak Singh Marg, Connaught Place, New Delhi, India","institution_ids":["https://openalex.org/I2800585909"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113820534","display_name":"Smita Neelkanth Deshpande","orcid":"https://orcid.org/0000-0001-7770-9657","observed_orcids":["https://orcid.org/0000-0001-7770-9657"]},"institutions":[{"id":"https://openalex.org/I2800585909","display_name":"Atal Bihari Vajpayee Institute of Medical Sciences and Dr. Ram Manohar Lohia Hospital","ror":"https://ror.org/00qa63322","country_code":"IN","type":"funder","lineage":["https://openalex.org/I2800585909"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Smita Neelkanth Deshpande","raw_affiliation_strings":["Department of Psychiatry, Postgraduate Institute of Medical Education and Research-Dr. Ram Manohar Lohia Hospital, Baba Kharak Singh Marg, Connaught Place, New Delhi, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychiatry, Postgraduate Institute of Medical Education and Research-Dr. Ram Manohar Lohia Hospital, Baba Kharak Singh Marg, Connaught Place, New Delhi, India","institution_ids":["https://openalex.org/I2800585909"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5023716414","display_name":"Bittianda Kuttapa Thelma","orcid":"https://orcid.org/0000-0002-2154-5443","observed_orcids":["https://orcid.org/0000-0002-2154-5443"]},"institutions":[{"id":"https://openalex.org/I110166357","display_name":"University of Delhi","ror":"https://ror.org/04gzb2213","country_code":"IN","type":"education","lineage":["https://openalex.org/I110166357"]}],"countries":["IN"],"is_corresponding":true,"raw_author_name":"B.K. Thelma","raw_affiliation_strings":["Department of Genetics, University of Delhi South Campus, Benito Juarez Road"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Genetics, University of Delhi South Campus, Benito Juarez Road","institution_ids":["https://openalex.org/I110166357"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5023716414"],"corresponding_institution_ids":["https://openalex.org/I110166357"],"apc_list":null,"apc_paid":null,"fwci":0.3469,"has_fulltext":true,"cited_by_count":7,"citation_normalized_percentile":{"value":0.57862364,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"30","issue":"5","first_page":"125","last_page":"135"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10023","display_name":"Schizophrenia research and treatment","score":0.9937000274658203,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10023","display_name":"Schizophrenia research and treatment","score":0.9937000274658203,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10056","display_name":"Neurotransmitter Receptor Influence on Behavior","score":0.0044999998062849045,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10261","display_name":"Genetic Associations and Epidemiology","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/schizophrenia","display_name":"schizophrenia","score":0.8949999809265137},{"id":"https://openalex.org/keywords/tardive-dyskinesia","display_name":"tardive dyskinesia","score":0.9929999709129333},{"id":"https://openalex.org/keywords/drd2","display_name":"DRD2","score":0.7990000247955322},{"id":"https://openalex.org/keywords/catechol-o-methyltransferase","display_name":"catechol-O-methyltransferase","score":0.9520000219345093},{"id":"https://openalex.org/keywords/comt-val158met-polymorphism","display_name":"COMT Val158Met polymorphism","score":1.0},{"id":"https://openalex.org/keywords/single-nucleotide-polymorphisms","display_name":"single nucleotide polymorphisms","score":0.9760000109672546},{"id":"https://openalex.org/keywords/cognitive-function","display_name":"cognitive function","score":0.5509999990463257},{"id":"https://openalex.org/keywords/smoking","display_name":"smoking","score":0.7940000295639038},{"id":"https://openalex.org/keywords/endophenotypes","display_name":"endophenotypes","score":0.7509999871253967},{"id":"https://openalex.org/keywords/dopamine-d2-receptor","display_name":"dopamine D2 receptor","score":0.6639999747276306},{"id":"https://openalex.org/keywords/gene-environment-interaction","display_name":"gene-environment interaction","score":0.6830000281333923},{"id":"https://openalex.org/keywords/abnormal-involuntary-movement-scale","display_name":"Abnormal Involuntary Movement Scale","score":0.7990000247955322}],"concepts":[{"id":"https://openalex.org/C2778524067","wikidata":"https://www.wikidata.org/wiki/Q17142059","display_name":"rs4680","level":5,"score":0.9658458232879639},{"id":"https://openalex.org/C2779158372","wikidata":"https://www.wikidata.org/wiki/Q1546328","display_name":"Tardive dyskinesia","level":3,"score":0.9584288597106934},{"id":"https://openalex.org/C2776412080","wikidata":"https://www.wikidata.org/wiki/Q7431605","display_name":"Schizophrenia (object-oriented programming)","level":2,"score":0.6250501871109009},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5478725433349609},{"id":"https://openalex.org/C2780405171","wikidata":"https://www.wikidata.org/wiki/Q629444","display_name":"Dyskinesia","level":4,"score":0.5369235277175903},{"id":"https://openalex.org/C2780135775","wikidata":"https://www.wikidata.org/wiki/Q7233251","display_name":"Positive and Negative Syndrome Scale","level":3,"score":0.4830549359321594},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4587843716144562},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.42313140630722046},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.41152238845825195},{"id":"https://openalex.org/C2779727114","wikidata":"https://www.wikidata.org/wiki/Q170082","display_name":"Psychosis","level":2,"score":0.2968025505542755},{"id":"https://openalex.org/C185361966","wikidata":"https://www.wikidata.org/wiki/Q94291140","display_name":"Catechol-O-methyl transferase","level":4,"score":0.22957029938697815},{"id":"https://openalex.org/C180754005","wikidata":"https://www.wikidata.org/wiki/Q80726","display_name":"Allele","level":3,"score":0.17363429069519043},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.05624750256538391},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0},{"id":"https://openalex.org/C2779734285","wikidata":"https://www.wikidata.org/wiki/Q11085","display_name":"Parkinson's disease","level":3,"score":0.0},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000071057","descriptor_name":"Tardive Dyskinesia","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D000071057","descriptor_name":"Tardive Dyskinesia","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D000071057","descriptor_name":"Tardive Dyskinesia","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000483","descriptor_name":"Alleles","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002394","descriptor_name":"Catechol O-Methyltransferase","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D002394","descriptor_name":"Catechol O-Methyltransferase","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D003071","descriptor_name":"Cognition","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005787","descriptor_name":"Gene Frequency","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D005838","descriptor_name":"Genotype","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011569","descriptor_name":"Psychiatric Status Rating Scales","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012559","descriptor_name":"Schizophrenia","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D012559","descriptor_name":"Schizophrenia","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012559","descriptor_name":"Schizophrenia","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D012907","descriptor_name":"Smoking","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D014150","descriptor_name":"Antipsychotic Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D017448","descriptor_name":"Receptors, Dopamine D2","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D017448","descriptor_name":"Receptors, Dopamine D2","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D020641","descriptor_name":"Polymorphism, Single Nucleotide","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1097/ypg.0000000000000258","doi":"https://doi.org/10.1097/ypg.0000000000000258","is_oa":false,"landing_page_url":"https://doi.org/10.1097/ypg.0000000000000258","pdf_url":null,"source":{"id":"https://openalex.org/S41645954","display_name":"Psychiatric Genetics","issn_l":"0955-8829","issn":["0955-8829","1473-5873"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-3","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Psychiatric Genetics","raw_type":"journal-article"},{"id":"pmid:32931693","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/32931693","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Psychiatric genetics","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:10111058","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/10111058","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC10111058/pdf/nihms-1888627.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Psychiatr Genet","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:10111058","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/10111058","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC10111058/pdf/nihms-1888627.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Psychiatr Genet","raw_type":"Text"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":1.0,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[{"id":"https://openalex.org/G1240563409","display_name":null,"funder_award_id":"BT/IC-2/00/smita/99","funder_id":"https://openalex.org/F4320320717","funder_display_name":"Department of Biotechnology, Ministry of Science and Technology, India"},{"id":"https://openalex.org/G1574343610","display_name":null,"funder_award_id":"BT/PR2425/Med/13/089/2001","funder_id":"https://openalex.org/F4320320717","funder_display_name":"Department of Biotechnology, Ministry of Science and Technology, India"},{"id":"https://openalex.org/G5912937303","display_name":null,"funder_award_id":"BT/IC-2/Israel/Deshpande/2002","funder_id":"https://openalex.org/F4320320717","funder_display_name":"Department of Biotechnology, Ministry of Science and Technology, India"},{"id":"https://openalex.org/G6674922341","display_name":"Genetic Susceptibility in Schizophrenia","funder_award_id":"R01MH056242","funder_id":"https://openalex.org/F4320337346","funder_display_name":"National Institute of Mental Health"},{"id":"https://openalex.org/G6837003917","display_name":"High Performance Computing for Biomedical Research","funder_award_id":"P41RR006009","funder_id":"https://openalex.org/F4320337375","funder_display_name":"National Center for Research Resources"},{"id":"https://openalex.org/G9000891499","display_name":"Psychiatric research infrastructure for intervention and implementation in India \u2013 TEAMS","funder_award_id":"D43TW009114","funder_id":"https://openalex.org/F4320337356","funder_display_name":"Fogarty International Center"}],"funders":[{"id":"https://openalex.org/F4320309636","display_name":"University of Minnesota","ror":"https://ror.org/03grvy078"},{"id":"https://openalex.org/F4320320717","display_name":"Department of Biotechnology, Ministry of Science and Technology, India","ror":"https://ror.org/03tjsyq23"},{"id":"https://openalex.org/F4320334771","display_name":"Science and Engineering Research Board","ror":"https://ror.org/03ffdsr55"},{"id":"https://openalex.org/F4320337346","display_name":"National Institute of Mental Health","ror":"https://ror.org/04xeg9z08"},{"id":"https://openalex.org/F4320337356","display_name":"Fogarty International Center","ror":"https://ror.org/02xey9a22"},{"id":"https://openalex.org/F4320337375","display_name":"National Center for Research Resources","ror":"https://ror.org/04pw6fb54"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3036924518.pdf","grobid_xml":"https://content.openalex.org/works/W3036924518.grobid-xml"},"referenced_works_count":78,"referenced_works":["https://openalex.org/W33405318","https://openalex.org/W429766147","https://openalex.org/W1546116904","https://openalex.org/W1546289896","https://openalex.org/W1872072116","https://openalex.org/W1965858324","https://openalex.org/W1966111889","https://openalex.org/W1967291383","https://openalex.org/W1968959382","https://openalex.org/W1970537882","https://openalex.org/W1972531895","https://openalex.org/W1972661776","https://openalex.org/W1973937884","https://openalex.org/W1982602032","https://openalex.org/W1988118023","https://openalex.org/W1988775970","https://openalex.org/W1993367804","https://openalex.org/W1993796018","https://openalex.org/W1996330474","https://openalex.org/W1996395058","https://openalex.org/W1996466545","https://openalex.org/W1997342204","https://openalex.org/W1999300426","https://openalex.org/W2007701693","https://openalex.org/W2009479700","https://openalex.org/W2009823135","https://openalex.org/W2018410781","https://openalex.org/W2019714280","https://openalex.org/W2026108793","https://openalex.org/W2029383380","https://openalex.org/W2032248619","https://openalex.org/W2035501864","https://openalex.org/W2036416641","https://openalex.org/W2039715812","https://openalex.org/W2052352110","https://openalex.org/W2054667633","https://openalex.org/W2062507339","https://openalex.org/W2064915698","https://openalex.org/W2065027511","https://openalex.org/W2066278769","https://openalex.org/W2067877506","https://openalex.org/W2068258189","https://openalex.org/W2072486526","https://openalex.org/W2073579715","https://openalex.org/W2078082457","https://openalex.org/W2079042530","https://openalex.org/W2085562256","https://openalex.org/W2096184992","https://openalex.org/W2097142850","https://openalex.org/W2100040984","https://openalex.org/W2101357408","https://openalex.org/W2108696245","https://openalex.org/W2113121748","https://openalex.org/W2119226169","https://openalex.org/W2125738714","https://openalex.org/W2131871863","https://openalex.org/W2132495630","https://openalex.org/W2132569582","https://openalex.org/W2132980997","https://openalex.org/W2137350840","https://openalex.org/W2140606211","https://openalex.org/W2141878312","https://openalex.org/W2143110843","https://openalex.org/W2145602532","https://openalex.org/W2157614591","https://openalex.org/W2159122633","https://openalex.org/W2161633633","https://openalex.org/W2165329858","https://openalex.org/W2171958702","https://openalex.org/W2202464924","https://openalex.org/W2409713973","https://openalex.org/W2801150824","https://openalex.org/W3018317538","https://openalex.org/W4250388848","https://openalex.org/W4285121237","https://openalex.org/W4413979542","https://openalex.org/W6600002178","https://openalex.org/W6839485592"],"related_works":["https://openalex.org/W4390116459","https://openalex.org/W4385264877","https://openalex.org/W1982602032","https://openalex.org/W2014666009","https://openalex.org/W2393112486","https://openalex.org/W4386898645","https://openalex.org/W3140807805","https://openalex.org/W4395689370","https://openalex.org/W2048269623","https://openalex.org/W2392900685"],"abstract_inverted_index":{"OBJECTIVE:":[0],"The":[1,188],"aim":[2],"of":[3,11,29,53,105,115,122,136,156,191,221,226,234,280,285,295,339],"the":[4,9],"study":[5],"is":[6],"to":[7,357,359],"test":[8],"association":[10,114,121,220,256,279,294,313,338],"a":[12],"functional":[13,31],"variant":[14],"each":[15],"in":[16,34,38,58,228,236,263,287,333,343],"DRD2":[17,35],"and":[18,23,36,50,57,76,82,87,153,199,248,299,306,325,336,362],"COMT":[19,39],"genes":[20,355],"with":[21,60,118,127,183,209,223,260,282,297,314,326,341,345],"schizophrenia":[22,42,346],"its":[24],"endophenotypes.":[25],"BASIC":[26],"METHODS:":[27],"Effect":[28],"two":[30,116],"variants":[32],"rs1076560":[33,192,222,296],"rs4680":[37,123,146,200,281,340],"on":[40],"(1)":[41],"(502":[43],"cases,":[44,91],"448":[45],"controls)":[46],"diagnosed":[47],"by":[48,69,80,95,269],"Diagnostic":[49],"Statistical":[51],"Manual":[52],"Mental":[54],"Disorders-IV":[55],"criteria":[56],"subsets":[59],"(2)":[61],"tardive":[62,128,157,185,212,229,237,249,264,288,360],"dyskinesia":[63,129,186,250,289,361],"(80":[64],"positive,":[65],"103":[66],"negative),":[67],"assessed":[68,79],"Abnormal":[70],"Involuntary":[71],"Movement":[72],"Scale":[73,85],"(AIMS),":[74],"positive":[75],"negative":[77,224],"symptoms":[78],"Positive":[81],"Negative":[83],"Syndrome":[84],"(PANSS)":[86],"(3)":[88],"cognition":[89,363],"(299":[90],"245":[92],"controls),":[93],"estimated":[94],"Penn":[96],"Computerized":[97],"Neurocognitive":[98],"Battery,":[99],"were":[100,181,207,267,350],"analysed":[101],"either":[102],"using":[103,272],"analysis":[104,271],"variance":[106],"(ANOVA)":[107],"or":[108],"regression":[109,270],"analysis.":[110],"MAIN":[111],"RESULTS:":[112],"No":[113],"SNPs":[117],"schizophrenia,":[119],"but":[120],"(P":[124,215,252,257,276,302,309,318,322,347],"<":[125],"0.05)":[126,259,332],"was":[130,291],"observed.":[131,292],"On":[132],"ANOVA,":[133],"main":[134,189],"effect":[135,155,190],"smoking":[137],"[F(2,148)":[138,147,159,193,201],"=":[139,142,148,151,160,163,167,170,174,177,194,197,202,205,216,218,242,253,258,277,303,310,319,323,331,348],"16.3;":[140],"P":[141,150,162,169,176,196,204,241,330],"3.9":[143],"\u00d7":[144,179,244,246],"10];":[145],"3.3;":[149],"0.04]":[152],"interaction":[154],"dyskinesia-status*Smoking":[158],"5.4,":[161],"0.006];":[164],"Smoking*rs1076560":[165],"[F(3,148)":[166],"3.6;":[168],"0.01];":[171],"Smoking*rs4680":[172],"[F(4,148)":[173],"5.3;":[175],"4.7":[178],"10]":[180],"significant":[182,208],"AIMS":[184],"score.":[187],"4.5;":[195],"0.013]":[198],"4.0;":[203],"0.02]":[206],"limb":[210],"truncal":[211],"dyskinesia.":[213],"Allelic/genotypic":[214,293],"0.004/P":[217],"0.01)":[219],"scale":[225],"PANSS":[227,235,286],"dyskinesia-negative;":[230],"diminished":[231],"expression":[232],"factor":[233,262,284],"dyskinesia-negative":[238],"subcohort":[239],"(allelic/genotypic":[240],"3.3":[243],"10/6.6":[245],"10)":[247],"cohorts":[251],"0.003/0.002);":[254],"genotypic":[255],"disorganised/concrete":[261],"dyskinesia-positive":[265],"subcohorts":[266],"observed":[268],"gPLINKv2.050.":[273],"Further":[274],"allelic/genotypic":[275],"0.02)":[278],"depressed":[283],"cohort":[290],"abstraction":[298,305],"mental":[300,307],"flexibilityaccuracy":[301],"0.03/0.04),":[304],"flexibilityefficiency":[308],"0.01/0.02);":[311],"allelic":[312,337],"spatial":[315,327],"abilityprocessing":[316],"speed":[317],"0.03),":[320],"emotionefficiency":[321,342],"0.05);":[324],"abilityefficiency":[328],"(genotypic,":[329],"healthy":[334],"controls":[335],"cases":[344],"0.04)":[349],"notable.":[351],"PRINCIPAL":[352],"CONCLUSION:":[353],"Dopaminergic":[354],"seem":[356],"contribute":[358],"warranting":[364],"replication.":[365]},"counts_by_year":[{"year":2026,"cited_by_count":4},{"year":2025,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2020-06-25T00:00:00"}
