{"id":"https://openalex.org/W3036639088","doi":"https://doi.org/10.1007/s10384-020-00748-x","title":"Intraocular pressure-lowering effect of omidenepag isopropyl in latanoprost non-/low-responder patients with primary open-angle glaucoma or ocular hypertension: the FUJI study","display_name":"Intraocular pressure-lowering effect of omidenepag isopropyl in latanoprost non-/low-responder patients with primary open-angle glaucoma or ocular hypertension: the FUJI study","publication_year":2020,"publication_date":"2020-06-22","ids":{"openalex":"https://openalex.org/W3036639088","doi":"https://doi.org/10.1007/s10384-020-00748-x","mag":"3036639088","pmid":"https://pubmed.ncbi.nlm.nih.gov/32572719"},"language":"en","primary_location":{"id":"doi:10.1007/s10384-020-00748-x","doi":"https://doi.org/10.1007/s10384-020-00748-x","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s10384-020-00748-x","pdf_url":null,"source":{"id":"https://openalex.org/S171503191","display_name":"Japanese Journal of Ophthalmology","issn_l":"0021-5155","issn":["0021-5155","1613-2246"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","doyens","jufo-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Japanese Journal of Ophthalmology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5053803582","display_name":"Makoto Aihara","orcid":"https://orcid.org/0000-0001-6810-0583","observed_orcids":["https://orcid.org/0000-0001-6810-0583"]},"institutions":[{"id":"https://openalex.org/I74801974","display_name":"The University of Tokyo","ror":"https://ror.org/057zh3y96","country_code":"JP","type":"education","lineage":["https://openalex.org/I74801974"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Makoto Aihara","raw_affiliation_strings":["Ophthalmology, University of Tokyo, Tokyo, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Ophthalmology, University of Tokyo, Tokyo, Japan","institution_ids":["https://openalex.org/I74801974"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000825873","display_name":"Auli Ropo","orcid":"https://orcid.org/0009-0009-5603-9020","observed_orcids":["https://orcid.org/0009-0009-5603-9020"]},"institutions":[{"id":"https://openalex.org/I4210107716","display_name":"Santen (Finland)","ror":"https://ror.org/01mhc8r12","country_code":"FI","type":"company","lineage":["https://openalex.org/I149737975","https://openalex.org/I4210107716"]}],"countries":["FI"],"is_corresponding":true,"raw_author_name":"Auli Ropo","raw_affiliation_strings":["Santen Oy, Vantaa, Finland. auli.ropo@santen.com","Santen Oy, Vantaa, Finland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Santen Oy, Vantaa, Finland. auli.ropo@santen.com","institution_ids":[]},{"raw_affiliation_string":"Santen Oy, Vantaa, Finland","institution_ids":["https://openalex.org/I4210107716"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112420123","display_name":"Fenghe Lu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210099140","display_name":"Santen (United States)","ror":"https://ror.org/0108v8438","country_code":"US","type":"company","lineage":["https://openalex.org/I149737975","https://openalex.org/I4210099140"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Fenghe Lu","raw_affiliation_strings":["Santen Inc., Emeryville, CA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Santen Inc., Emeryville, CA, USA","institution_ids":["https://openalex.org/I4210099140"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045726263","display_name":"Hisashi Kawata","orcid":"https://orcid.org/0000-0002-5111-5401","observed_orcids":["https://orcid.org/0000-0002-5111-5401"]},"institutions":[{"id":"https://openalex.org/I149737975","display_name":"Santen (Japan)","ror":"https://ror.org/032msy923","country_code":"JP","type":"company","lineage":["https://openalex.org/I149737975"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Hisashi Kawata","raw_affiliation_strings":["Santen Pharmaceutical Co., Ltd, Osaka, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Santen Pharmaceutical Co., Ltd, Osaka, Japan","institution_ids":["https://openalex.org/I149737975"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005954913","display_name":"Akihiro Iwata","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I149737975","display_name":"Santen (Japan)","ror":"https://ror.org/032msy923","country_code":"JP","type":"company","lineage":["https://openalex.org/I149737975"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Akihiro Iwata","raw_affiliation_strings":["Santen Pharmaceutical Co., Ltd, Osaka, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Santen Pharmaceutical Co., Ltd, Osaka, Japan","institution_ids":["https://openalex.org/I149737975"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051725756","display_name":"Noriko Odani\u2010Kawabata","orcid":"https://orcid.org/0000-0001-9776-6077","observed_orcids":["https://orcid.org/0000-0001-9776-6077"]},"institutions":[{"id":"https://openalex.org/I149737975","display_name":"Santen (Japan)","ror":"https://ror.org/032msy923","country_code":"JP","type":"company","lineage":["https://openalex.org/I149737975"]},{"id":"https://openalex.org/I4210099140","display_name":"Santen (United States)","ror":"https://ror.org/0108v8438","country_code":"US","type":"company","lineage":["https://openalex.org/I149737975","https://openalex.org/I4210099140"]}],"countries":["JP","US"],"is_corresponding":false,"raw_author_name":"Noriko Odani-Kawabata","raw_affiliation_strings":["Santen Inc., Emeryville, CA, USA","Santen Pharmaceutical Co., Ltd, Osaka, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Santen Inc., Emeryville, CA, USA","institution_ids":["https://openalex.org/I4210099140"]},{"raw_affiliation_string":"Santen Pharmaceutical Co., Ltd, Osaka, Japan","institution_ids":["https://openalex.org/I149737975"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5109417546","display_name":"Naveed K. Shams","orcid":"https://orcid.org/0009-0001-8484-6032","observed_orcids":["https://orcid.org/0009-0001-8484-6032"]},"institutions":[{"id":"https://openalex.org/I149737975","display_name":"Santen (Japan)","ror":"https://ror.org/032msy923","country_code":"JP","type":"company","lineage":["https://openalex.org/I149737975"]},{"id":"https://openalex.org/I4210099140","display_name":"Santen (United States)","ror":"https://ror.org/0108v8438","country_code":"US","type":"company","lineage":["https://openalex.org/I149737975","https://openalex.org/I4210099140"]}],"countries":["JP","US"],"is_corresponding":false,"raw_author_name":"Naveed Shams","raw_affiliation_strings":["Santen Inc., Emeryville, CA, USA","Santen Pharmaceutical Co., Ltd, Osaka, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Santen Inc., Emeryville, CA, USA","institution_ids":["https://openalex.org/I4210099140"]},{"raw_affiliation_string":"Santen Pharmaceutical Co., Ltd, Osaka, Japan","institution_ids":["https://openalex.org/I149737975"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5000825873"],"corresponding_institution_ids":["https://openalex.org/I4210107716"],"apc_list":{"value":3790,"currency":"USD","value_usd":3790},"apc_paid":null,"fwci":7.1855,"has_fulltext":false,"cited_by_count":56,"citation_normalized_percentile":{"value":0.98430383,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"64","issue":"4","first_page":"398","last_page":"406"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10250","display_name":"Glaucoma and retinal disorders","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10250","display_name":"Glaucoma and retinal disorders","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13467","display_name":"Drug-Induced Ocular Toxicity","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10563","display_name":"Corneal surgery and disorders","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/ep2-receptor-agonist","display_name":"EP2 receptor agonist","score":0.8330000042915344},{"id":"https://openalex.org/keywords/intraocular-pressure-reduction","display_name":"intraocular pressure reduction","score":0.8140000104904175},{"id":"https://openalex.org/keywords/primary-open-angle-glaucoma","display_name":"primary open-angle glaucoma","score":0.9070000052452087},{"id":"https://openalex.org/keywords/ocular-hypertension","display_name":"ocular hypertension","score":1.0},{"id":"https://openalex.org/keywords/prodrugs","display_name":"prodrugs","score":0.5360000133514404},{"id":"https://openalex.org/keywords/eye-drops","display_name":"eye drops","score":0.7889999747276306},{"id":"https://openalex.org/keywords/adverse-drug-reactions","display_name":"adverse drug reactions","score":0.6269999742507935}],"concepts":[{"id":"https://openalex.org/C2776740260","wikidata":"https://www.wikidata.org/wiki/Q634959","display_name":"Latanoprost","level":3,"score":0.9705595374107361},{"id":"https://openalex.org/C2991803831","wikidata":"https://www.wikidata.org/wiki/Q159701","display_name":"Open angle glaucoma","level":3,"score":0.8143991827964783},{"id":"https://openalex.org/C2776521421","wikidata":"https://www.wikidata.org/wiki/Q9294051","display_name":"Ocular hypertension","level":3,"score":0.7394701838493347},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6905136108398438},{"id":"https://openalex.org/C2781092963","wikidata":"https://www.wikidata.org/wiki/Q650050","display_name":"Intraocular pressure","level":2,"score":0.684023916721344},{"id":"https://openalex.org/C104264131","wikidata":"https://www.wikidata.org/wiki/Q898637","display_name":"Isopropyl","level":2,"score":0.683071494102478},{"id":"https://openalex.org/C2778527774","wikidata":"https://www.wikidata.org/wiki/Q159701","display_name":"Glaucoma","level":2,"score":0.6365346908569336},{"id":"https://openalex.org/C118487528","wikidata":"https://www.wikidata.org/wiki/Q161437","display_name":"Ophthalmology","level":1,"score":0.6323373317718506},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.16057685017585754},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000072776","descriptor_name":"Slit Lamp Microscopy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000077338","descriptor_name":"Latanoprost","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000959","descriptor_name":"Antihypertensive Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005902","descriptor_name":"Glaucoma, Open-Angle","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D005902","descriptor_name":"Glaucoma, Open-Angle","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D005998","descriptor_name":"Glycine","qualifier_ui":"Q000031","qualifier_name":"analogs & derivatives","is_major_topic":true},{"descriptor_ui":"D005998","descriptor_name":"Glycine","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007429","descriptor_name":"Intraocular Pressure","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D007429","descriptor_name":"Intraocular Pressure","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009798","descriptor_name":"Ocular Hypertension","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D009798","descriptor_name":"Ocular Hypertension","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D009883","descriptor_name":"Ophthalmic Solutions","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011720","descriptor_name":"Pyrazoles","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D011725","descriptor_name":"Pyridines","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D014065","descriptor_name":"Tonometry, Ocular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D058307","descriptor_name":"Receptors, Prostaglandin E, EP2 Subtype","qualifier_ui":"Q000819","qualifier_name":"agonists","is_major_topic":true},{"descriptor_ui":"D060433","descriptor_name":"Administration, Ophthalmic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1007/s10384-020-00748-x","doi":"https://doi.org/10.1007/s10384-020-00748-x","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s10384-020-00748-x","pdf_url":null,"source":{"id":"https://openalex.org/S171503191","display_name":"Japanese Journal of Ophthalmology","issn_l":"0021-5155","issn":["0021-5155","1613-2246"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","doyens","jufo-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Japanese Journal of Ophthalmology","raw_type":"journal-article"},{"id":"pmid:32572719","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/32572719","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Japanese journal of ophthalmology","raw_type":"Clinical Trial, Phase III"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":1.0,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/clinical-trial","display_name":"Clinical Trial"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320322516","display_name":"Santen","ror":"https://ror.org/032msy923"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":28,"referenced_works":["https://openalex.org/W84625781","https://openalex.org/W1963522904","https://openalex.org/W1968988621","https://openalex.org/W1977730321","https://openalex.org/W1984673463","https://openalex.org/W1989215324","https://openalex.org/W1999521109","https://openalex.org/W2000248632","https://openalex.org/W2017986453","https://openalex.org/W2049093711","https://openalex.org/W2059126872","https://openalex.org/W2064116153","https://openalex.org/W2072555446","https://openalex.org/W2080565505","https://openalex.org/W2090110993","https://openalex.org/W2091063199","https://openalex.org/W2140594570","https://openalex.org/W2153367682","https://openalex.org/W2269199031","https://openalex.org/W2334551273","https://openalex.org/W2729341911","https://openalex.org/W2737143773","https://openalex.org/W2783861782","https://openalex.org/W2827702279","https://openalex.org/W2884353615","https://openalex.org/W2918259642","https://openalex.org/W4240661191","https://openalex.org/W4249686622"],"related_works":["https://openalex.org/W3035005545","https://openalex.org/W4387765339","https://openalex.org/W4400693381","https://openalex.org/W4224608775","https://openalex.org/W3204571829","https://openalex.org/W2918259642","https://openalex.org/W2914563365","https://openalex.org/W4288684464","https://openalex.org/W3017005220","https://openalex.org/W4412630230"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":11},{"year":2024,"cited_by_count":6},{"year":2023,"cited_by_count":14},{"year":2022,"cited_by_count":12},{"year":2021,"cited_by_count":9},{"year":2020,"cited_by_count":1},{"year":2018,"cited_by_count":2}],"updated_date":"2026-11-12T12:28:57.059296","created_date":"2020-06-25T00:00:00"}