{"id":"https://openalex.org/W3035398293","doi":"https://doi.org/10.1002/dmrr.3366","title":"Diabetes mellitus induced by immune checkpoint inhibitors","display_name":"Diabetes mellitus induced by immune checkpoint inhibitors","publication_year":2020,"publication_date":"2020-06-16","ids":{"openalex":"https://openalex.org/W3035398293","doi":"https://doi.org/10.1002/dmrr.3366","mag":"3035398293","pmid":"https://pubmed.ncbi.nlm.nih.gov/32543027"},"language":"en","primary_location":{"id":"doi:10.1002/dmrr.3366","doi":"https://doi.org/10.1002/dmrr.3366","is_oa":false,"landing_page_url":"https://doi.org/10.1002/dmrr.3366","pdf_url":null,"source":{"id":"https://openalex.org/S83251063","display_name":"Diabetes/Metabolism Research and Reviews","issn_l":"1520-7552","issn":["1520-7552","1520-7560"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Diabetes/Metabolism Research and Reviews","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100942736","display_name":"Zhenjiang Zheng","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I24185976","display_name":"Sichuan University","ror":"https://ror.org/011ashp19","country_code":"CN","type":"education","lineage":["https://openalex.org/I24185976"]},{"id":"https://openalex.org/I4210089761","display_name":"West China Hospital of Sichuan University","ror":"https://ror.org/007mrxy13","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210089761"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zhenjiang Zheng","raw_affiliation_strings":["Department of Pancreatic Surgery, West China Hospital, Sichuan University, Chengdu, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pancreatic Surgery, West China Hospital, Sichuan University, Chengdu, China","institution_ids":["https://openalex.org/I24185976","https://openalex.org/I4210089761"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100459732","display_name":"Ya Liu","orcid":"https://orcid.org/0000-0002-0750-4979","observed_orcids":["https://orcid.org/0000-0002-0750-4979"]},"institutions":[{"id":"https://openalex.org/I24185976","display_name":"Sichuan University","ror":"https://ror.org/011ashp19","country_code":"CN","type":"education","lineage":["https://openalex.org/I24185976"]},{"id":"https://openalex.org/I4210089761","display_name":"West China Hospital of Sichuan University","ror":"https://ror.org/007mrxy13","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210089761"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ya Liu","raw_affiliation_strings":["Department of Pancreatic Surgery, West China Hospital, Sichuan University, Chengdu, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pancreatic Surgery, West China Hospital, Sichuan University, Chengdu, China","institution_ids":["https://openalex.org/I24185976","https://openalex.org/I4210089761"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100404945","display_name":"Jie Yang","orcid":"https://orcid.org/0000-0003-4346-9100","observed_orcids":["https://orcid.org/0000-0003-4346-9100"]},"institutions":[{"id":"https://openalex.org/I24185976","display_name":"Sichuan University","ror":"https://ror.org/011ashp19","country_code":"CN","type":"education","lineage":["https://openalex.org/I24185976"]},{"id":"https://openalex.org/I4210089761","display_name":"West China Hospital of Sichuan University","ror":"https://ror.org/007mrxy13","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210089761"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jie Yang","raw_affiliation_strings":["Department of Pancreatic Surgery, West China Hospital, Sichuan University, Chengdu, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pancreatic Surgery, West China Hospital, Sichuan University, Chengdu, China","institution_ids":["https://openalex.org/I24185976","https://openalex.org/I4210089761"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085085373","display_name":"Chunlu Tan","orcid":"https://orcid.org/0000-0002-7280-8776","observed_orcids":["https://orcid.org/0000-0002-7280-8776","https://orcid.org/0000-0002-1440-0430"]},"institutions":[{"id":"https://openalex.org/I24185976","display_name":"Sichuan University","ror":"https://ror.org/011ashp19","country_code":"CN","type":"education","lineage":["https://openalex.org/I24185976"]},{"id":"https://openalex.org/I4210089761","display_name":"West China Hospital of Sichuan University","ror":"https://ror.org/007mrxy13","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210089761"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Chunlu Tan","raw_affiliation_strings":["Department of Pancreatic Surgery, West China Hospital, Sichuan University, Chengdu, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pancreatic Surgery, West China Hospital, Sichuan University, Chengdu, China","institution_ids":["https://openalex.org/I24185976","https://openalex.org/I4210089761"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102000136","display_name":"Li Zhou","orcid":"https://orcid.org/0000-0002-6736-0057","observed_orcids":["https://orcid.org/0000-0002-6736-0057"]},"institutions":[{"id":"https://openalex.org/I24185976","display_name":"Sichuan University","ror":"https://ror.org/011ashp19","country_code":"CN","type":"education","lineage":["https://openalex.org/I24185976"]},{"id":"https://openalex.org/I4210089761","display_name":"West China Hospital of Sichuan University","ror":"https://ror.org/007mrxy13","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210089761"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Li Zhou","raw_affiliation_strings":["Research Core Facility of West China Hospital, Sichuan University, Chengdu, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Research Core Facility of West China Hospital, Sichuan University, Chengdu, China","institution_ids":["https://openalex.org/I24185976","https://openalex.org/I4210089761"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100365485","display_name":"Xing Wang","orcid":"https://orcid.org/0000-0001-8762-5617","observed_orcids":["https://orcid.org/0000-0001-8762-5617"]},"institutions":[{"id":"https://openalex.org/I24185976","display_name":"Sichuan University","ror":"https://ror.org/011ashp19","country_code":"CN","type":"education","lineage":["https://openalex.org/I24185976"]},{"id":"https://openalex.org/I4210089761","display_name":"West China Hospital of Sichuan University","ror":"https://ror.org/007mrxy13","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210089761"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xing Wang","raw_affiliation_strings":["Department of Pancreatic Surgery, West China Hospital, Sichuan University, Chengdu, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pancreatic Surgery, West China Hospital, Sichuan University, Chengdu, China","institution_ids":["https://openalex.org/I24185976","https://openalex.org/I4210089761"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100659676","display_name":"Xiao Li","orcid":"https://orcid.org/0000-0003-4135-2275","observed_orcids":["https://orcid.org/0000-0003-4135-2275"]},"institutions":[{"id":"https://openalex.org/I4210093384","display_name":"Third People's Hospital of Chengdu","ror":"https://ror.org/00ebdgr24","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210093384"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Li Xiao","raw_affiliation_strings":["Department of Traditional Chinese Medicine, Chengdu Third People's Hospital, Chengdu, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Traditional Chinese Medicine, Chengdu Third People's Hospital, Chengdu, China","institution_ids":["https://openalex.org/I4210093384"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Shu Zhang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210093384","display_name":"Third People's Hospital of Chengdu","ror":"https://ror.org/00ebdgr24","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210093384"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Shu Zhang","raw_affiliation_strings":["Department of General Surgery, Chengdu Third People's Hospital, Chengdu, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of General Surgery, Chengdu Third People's Hospital, Chengdu, China","institution_ids":["https://openalex.org/I4210093384"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100757194","display_name":"Yonghua Chen","orcid":"https://orcid.org/0000-0002-9973-8843","observed_orcids":["https://orcid.org/0000-0002-9973-8843"]},"institutions":[{"id":"https://openalex.org/I24185976","display_name":"Sichuan University","ror":"https://ror.org/011ashp19","country_code":"CN","type":"education","lineage":["https://openalex.org/I24185976"]},{"id":"https://openalex.org/I4210089761","display_name":"West China Hospital of Sichuan University","ror":"https://ror.org/007mrxy13","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210089761"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Yonghua Chen","raw_affiliation_strings":["Department of Pancreatic Surgery, West China Hospital, Sichuan University, Chengdu, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pancreatic Surgery, West China Hospital, Sichuan University, Chengdu, China","institution_ids":["https://openalex.org/I24185976","https://openalex.org/I4210089761"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5101951692","display_name":"Xubao Liu","orcid":"https://orcid.org/0000-0002-1288-7089","observed_orcids":["https://orcid.org/0000-0002-1288-7089"]},"institutions":[{"id":"https://openalex.org/I24185976","display_name":"Sichuan University","ror":"https://ror.org/011ashp19","country_code":"CN","type":"education","lineage":["https://openalex.org/I24185976"]},{"id":"https://openalex.org/I4210089761","display_name":"West China Hospital of Sichuan University","ror":"https://ror.org/007mrxy13","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210089761"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Xubao Liu","raw_affiliation_strings":["Department of Pancreatic Surgery, West China Hospital, Sichuan University, Chengdu, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pancreatic Surgery, West China Hospital, Sichuan University, Chengdu, China","institution_ids":["https://openalex.org/I24185976","https://openalex.org/I4210089761"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5100757194","https://openalex.org/A5101951692"],"corresponding_institution_ids":["https://openalex.org/I24185976","https://openalex.org/I4210089761"],"apc_list":{"value":4100,"currency":"USD","value_usd":4100},"apc_paid":null,"fwci":0.4616,"has_fulltext":false,"cited_by_count":33,"citation_normalized_percentile":{"value":0.50086104,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":99},"biblio":{"volume":"37","issue":"1","first_page":"e3366","last_page":"e3366"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10158","display_name":"Cancer Immunotherapy and Biomarkers","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10158","display_name":"Cancer Immunotherapy and Biomarkers","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11171","display_name":"Diabetes and associated disorders","score":0.0010000000474974513,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11943","display_name":"Pharmacovigilance and Adverse Drug Reactions","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/3005","display_name":"Toxicology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/immune-checkpoint-inhibitors","display_name":"immune checkpoint inhibitors","score":0.9670000076293945},{"id":"https://openalex.org/keywords/immune-related-adverse-events","display_name":"immune-related adverse events","score":0.8560000061988831},{"id":"https://openalex.org/keywords/beta-cell-dysfunction","display_name":"beta-cell dysfunction","score":0.8090000152587891},{"id":"https://openalex.org/keywords/immune-related-endocrine-adverse-events","display_name":"immune-related endocrine adverse events","score":0.6669999957084656},{"id":"https://openalex.org/keywords/immunotherapy-toxicity","display_name":"immunotherapy toxicity","score":0.5830000042915344},{"id":"https://openalex.org/keywords/diabetes-management","display_name":"diabetes management","score":0.4819999933242798}],"concepts":[{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.6719220876693726},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.575465202331543},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.4845549166202545},{"id":"https://openalex.org/C2780851360","wikidata":"https://www.wikidata.org/wiki/Q21686041","display_name":"Immune checkpoint","level":4,"score":0.4659354090690613},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.4248321056365967},{"id":"https://openalex.org/C2777701055","wikidata":"https://www.wikidata.org/wiki/Q1427096","display_name":"Immunotherapy","level":3,"score":0.19940558075904846},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.1057288646697998}],"mesh":[{"descriptor_ui":"D000082082","descriptor_name":"Immune Checkpoint Inhibitors","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D003920","descriptor_name":"Diabetes Mellitus","qualifier_ui":"Q000139","qualifier_name":"chemically induced","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1002/dmrr.3366","doi":"https://doi.org/10.1002/dmrr.3366","is_oa":false,"landing_page_url":"https://doi.org/10.1002/dmrr.3366","pdf_url":null,"source":{"id":"https://openalex.org/S83251063","display_name":"Diabetes/Metabolism Research and Reviews","issn_l":"1520-7552","issn":["1520-7552","1520-7560"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Diabetes/Metabolism Research and Reviews","raw_type":"journal-article"},{"id":"pmid:32543027","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/32543027","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Diabetes/metabolism research and reviews","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":1.0}],"study_designs":[],"awards":[{"id":"https://openalex.org/G6472753157","display_name":null,"funder_award_id":"81602133","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":114,"referenced_works":["https://openalex.org/W1479705568","https://openalex.org/W1987246352","https://openalex.org/W1996398553","https://openalex.org/W2014077667","https://openalex.org/W2017712207","https://openalex.org/W2025157903","https://openalex.org/W2031364732","https://openalex.org/W2046445416","https://openalex.org/W2063264144","https://openalex.org/W2085247907","https://openalex.org/W2085604821","https://openalex.org/W2098906780","https://openalex.org/W2102684459","https://openalex.org/W2104347254","https://openalex.org/W2118239717","https://openalex.org/W2119218381","https://openalex.org/W2124089048","https://openalex.org/W2137631342","https://openalex.org/W2140875987","https://openalex.org/W2158840473","https://openalex.org/W2162856391","https://openalex.org/W2166662937","https://openalex.org/W2169351454","https://openalex.org/W2263759961","https://openalex.org/W2338994579","https://openalex.org/W2340628808","https://openalex.org/W2406019424","https://openalex.org/W2409477261","https://openalex.org/W2467060254","https://openalex.org/W2549481046","https://openalex.org/W2552653242","https://openalex.org/W2558893427","https://openalex.org/W2561370981","https://openalex.org/W2587595432","https://openalex.org/W2593283383","https://openalex.org/W2612166109","https://openalex.org/W2669889121","https://openalex.org/W2731673561","https://openalex.org/W2736166064","https://openalex.org/W2736948963","https://openalex.org/W2739132742","https://openalex.org/W2751649617","https://openalex.org/W2752018983","https://openalex.org/W2753432434","https://openalex.org/W2760410509","https://openalex.org/W2765216321","https://openalex.org/W2766033739","https://openalex.org/W2766633509","https://openalex.org/W2768429453","https://openalex.org/W2769764904","https://openalex.org/W2769908638","https://openalex.org/W2770404972","https://openalex.org/W2781484625","https://openalex.org/W2782261845","https://openalex.org/W2783137027","https://openalex.org/W2784120148","https://openalex.org/W2786816161","https://openalex.org/W2789465165","https://openalex.org/W2790076020","https://openalex.org/W2791483720","https://openalex.org/W2792945963","https://openalex.org/W2793937731","https://openalex.org/W2796159909","https://openalex.org/W2805387664","https://openalex.org/W2806832126","https://openalex.org/W2808224224","https://openalex.org/W2808896902","https://openalex.org/W2809615201","https://openalex.org/W2810537535","https://openalex.org/W2811140989","https://openalex.org/W2887577080","https://openalex.org/W2890553958","https://openalex.org/W2891536507","https://openalex.org/W2892862525","https://openalex.org/W2894642018","https://openalex.org/W2895634939","https://openalex.org/W2896274372","https://openalex.org/W2896438236","https://openalex.org/W2898845456","https://openalex.org/W2899357614","https://openalex.org/W2900360032","https://openalex.org/W2904477283","https://openalex.org/W2905314444","https://openalex.org/W2905400717","https://openalex.org/W2911188335","https://openalex.org/W2912452927","https://openalex.org/W2912454954","https://openalex.org/W2912725678","https://openalex.org/W2914118505","https://openalex.org/W2915650040","https://openalex.org/W2921353943","https://openalex.org/W2924070172","https://openalex.org/W2928722477","https://openalex.org/W2939312711","https://openalex.org/W2941271487","https://openalex.org/W2942674623","https://openalex.org/W2944384098","https://openalex.org/W2945674342","https://openalex.org/W2947893849","https://openalex.org/W2948397884","https://openalex.org/W2951530707","https://openalex.org/W2953669376","https://openalex.org/W2954626501","https://openalex.org/W2955445054","https://openalex.org/W2959253706","https://openalex.org/W2962807330","https://openalex.org/W2975864454","https://openalex.org/W2976286379","https://openalex.org/W2980012328","https://openalex.org/W2981366973","https://openalex.org/W2988124258","https://openalex.org/W3005370270","https://openalex.org/W4235479662","https://openalex.org/W6658205181"],"related_works":["https://openalex.org/W3211233610","https://openalex.org/W4414349773","https://openalex.org/W3107506789","https://openalex.org/W4382359180","https://openalex.org/W4402764153","https://openalex.org/W3131574412","https://openalex.org/W4380235552","https://openalex.org/W4400304053","https://openalex.org/W4392703573","https://openalex.org/W7123339033"],"abstract_inverted_index":{"Immune":[0],"checkpoint":[1],"inhibitors":[2],"(ICIs)":[3],"are":[4,70],"widely":[5],"used":[6],"in":[7],"oncology":[8],"for":[9],"their":[10],"favourable":[11],"antitumor":[12],"efficacy.":[13],"ICI":[14,91],"therapy":[15],"is":[16,32,38],"associated":[17],"with":[18],"a":[19],"unique":[20],"toxicity":[21],"profile":[22],"known":[23],"as":[24],"immune-related":[25],"adverse":[26,87],"events":[27],"(irAEs).":[28],"One":[29],"such":[30],"irAE":[31],"ICI-related":[33,68,96],"diabetes":[34],"mellitus":[35],"(DM),":[36],"which":[37],"relatively":[39],"uncommon":[40],"but":[41],"can":[42],"become":[43],"extremely":[44],"severe,":[45],"leading":[46],"to":[47,55,100],"irreversible":[48],"impairment":[49],"of":[50,67,85,95,105],"\u03b2-cells,":[51],"and":[52,61,83],"even":[53],"lead":[54],"death":[56],"if":[57],"not":[58,71],"promptly":[59],"recognised":[60],"properly":[62],"managed.":[63],"The":[64],"precise":[65],"mechanisms":[66,104],"DM":[69,97],"well":[72],"understood.":[73],"In":[74],"this":[75,86],"review,":[76],"we":[77],"summarise":[78],"the":[79,102],"clinical":[80],"characteristics,":[81],"pathophysiology,":[82],"management":[84],"effect":[88],"caused":[89],"by":[90],"therapy.":[92],"Deeper":[93],"investigation":[94],"may":[98],"contribute":[99],"elucidate":[101],"molecular":[103],"classical":[106],"type":[107],"1":[108],"DM.":[109]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":9},{"year":2024,"cited_by_count":7},{"year":2023,"cited_by_count":8},{"year":2022,"cited_by_count":6},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2020-06-19T00:00:00"}