{"id":"https://openalex.org/W3033332801","doi":"https://doi.org/10.1097/ccm.0000000000004446","title":"Central Venous-to-Arterial Pco 2 Difference and Central Venous Oxygen Saturation in the Detection of Extubation Failure in Critically Ill Patients*","display_name":"Central Venous-to-Arterial Pco 2 Difference and Central Venous Oxygen Saturation in the Detection of Extubation Failure in Critically Ill Patients*","publication_year":2020,"publication_date":"2020-06-10","ids":{"openalex":"https://openalex.org/W3033332801","doi":"https://doi.org/10.1097/ccm.0000000000004446","mag":"3033332801","pmid":"https://pubmed.ncbi.nlm.nih.gov/32520890"},"language":"en","primary_location":{"id":"doi:10.1097/ccm.0000000000004446","doi":"https://doi.org/10.1097/ccm.0000000000004446","is_oa":false,"landing_page_url":"https://doi.org/10.1097/ccm.0000000000004446","pdf_url":null,"source":{"id":"https://openalex.org/S108732581","display_name":"Critical Care Medicine","issn_l":"0090-3493","issn":["0090-3493","1530-0293"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Critical Care Medicine","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5028647748","display_name":"Jihad Mallat","orcid":"https://orcid.org/0000-0001-6372-7360","observed_orcids":["https://orcid.org/0000-0001-6372-7360"]},"institutions":[{"id":"https://openalex.org/I4210106350","display_name":"Centre Hospitalier de Lens","ror":"https://ror.org/01fbc7819","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210106350"]},{"id":"https://openalex.org/I4405266839","display_name":"Cleveland Clinic Abu Dhabi","ror":"https://ror.org/00042rr39","country_code":"AE","type":"healthcare","lineage":["https://openalex.org/I4405266839"]},{"id":"https://openalex.org/I98702875","display_name":"Universit\u00e9 de Caen Normandie","ror":"https://ror.org/051kpcy16","country_code":"FR","type":"education","lineage":["https://openalex.org/I4210105918","https://openalex.org/I98702875"]}],"countries":["AE","FR"],"is_corresponding":false,"raw_author_name":"Jihad Mallat","raw_affiliation_strings":["Department of Anesthesiology and Critical Care Medicine, Service de R\u00e9animation polyvalente, Centre Hospitalier du Dr. Schaffner, Lens Cedex, France","Department of Critical Care Medicine, Critical Care Institute, Cleveland Clinic Abu Dhabi, Abu Dhabi, United Arab Emirates","Normandy University, UNICAEN, ED 497, Caen, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Anesthesiology and Critical Care Medicine, Service de R\u00e9animation polyvalente, Centre Hospitalier du Dr. Schaffner, Lens Cedex, France","institution_ids":["https://openalex.org/I4210106350"]},{"raw_affiliation_string":"Department of Critical Care Medicine, Critical Care Institute, Cleveland Clinic Abu Dhabi, Abu Dhabi, United Arab Emirates","institution_ids":["https://openalex.org/I4405266839"]},{"raw_affiliation_string":"Normandy University, UNICAEN, ED 497, Caen, France","institution_ids":["https://openalex.org/I98702875"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065321379","display_name":"Fawzi Ali Baghdadi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210097159","display_name":"Assistance Publique \u2013 H\u00f4pitaux de Paris","ror":"https://ror.org/00pg5jh14","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Fawzi Ali Baghdadi","raw_affiliation_strings":["Department of Critical Care Medicine, Intensive Care Unit, Centre Hospitalier de Cambrai, Avenue de Paris, Cambrai Cedex, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Critical Care Medicine, Intensive Care Unit, Centre Hospitalier de Cambrai, Avenue de Paris, Cambrai Cedex, France","institution_ids":["https://openalex.org/I4210097159"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051735347","display_name":"Usman Mohammad","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210135031","display_name":"Centre Hospitalier d'Arras","ror":"https://ror.org/03fv6f056","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210135031"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Usman Mohammad","raw_affiliation_strings":["Department of Critical Care Medicine, Intensive Care Unit, Centre Hospitalier d\u2019Arras, Boulevard Georges Besnier, Arras Cedex, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Critical Care Medicine, Intensive Care Unit, Centre Hospitalier d\u2019Arras, Boulevard Georges Besnier, Arras Cedex, France","institution_ids":["https://openalex.org/I4210135031"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017958579","display_name":"Malcolm Lemyze","orcid":"https://orcid.org/0009-0000-1104-7777","observed_orcids":["https://orcid.org/0009-0000-1104-7777"]},"institutions":[{"id":"https://openalex.org/I4210135031","display_name":"Centre Hospitalier d'Arras","ror":"https://ror.org/03fv6f056","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210135031"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Malcolm Lemyze","raw_affiliation_strings":["Department of Critical Care Medicine, Intensive Care Unit, Centre Hospitalier d\u2019Arras, Boulevard Georges Besnier, Arras Cedex, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Critical Care Medicine, Intensive Care Unit, Centre Hospitalier d\u2019Arras, Boulevard Georges Besnier, Arras Cedex, France","institution_ids":["https://openalex.org/I4210135031"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038789888","display_name":"Johanna Temime","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210106350","display_name":"Centre Hospitalier de Lens","ror":"https://ror.org/01fbc7819","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210106350"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Johanna Temime","raw_affiliation_strings":["Department of Anesthesiology and Critical Care Medicine, Service de R\u00e9animation polyvalente, Centre Hospitalier du Dr. Schaffner, Lens Cedex, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Anesthesiology and Critical Care Medicine, Service de R\u00e9animation polyvalente, Centre Hospitalier du Dr. Schaffner, Lens Cedex, France","institution_ids":["https://openalex.org/I4210106350"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089709567","display_name":"Laurent Tronchon","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210106350","display_name":"Centre Hospitalier de Lens","ror":"https://ror.org/01fbc7819","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210106350"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Laurent Tronchon","raw_affiliation_strings":["Department of Anesthesiology and Critical Care Medicine, Service de R\u00e9animation polyvalente, Centre Hospitalier du Dr. Schaffner, Lens Cedex, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Anesthesiology and Critical Care Medicine, Service de R\u00e9animation polyvalente, Centre Hospitalier du Dr. Schaffner, Lens Cedex, France","institution_ids":["https://openalex.org/I4210106350"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022485888","display_name":"Didier Th\u00e9venin","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210106350","display_name":"Centre Hospitalier de Lens","ror":"https://ror.org/01fbc7819","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210106350"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Didier Thevenin","raw_affiliation_strings":["Department of Anesthesiology and Critical Care Medicine, Service de R\u00e9animation polyvalente, Centre Hospitalier du Dr. Schaffner, Lens Cedex, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Anesthesiology and Critical Care Medicine, Service de R\u00e9animation polyvalente, Centre Hospitalier du Dr. Schaffner, Lens Cedex, France","institution_ids":["https://openalex.org/I4210106350"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5107877394","display_name":"Marc-Olivier Fischer","orcid":"https://orcid.org/0000-0002-8887-2377","observed_orcids":["https://orcid.org/0000-0002-8887-2377"]},"institutions":[{"id":"https://openalex.org/I4210114068","display_name":"Centre Hospitalier Universitaire de Caen Normandie","ror":"https://ror.org/027arzy69","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210114068"]},{"id":"https://openalex.org/I98702875","display_name":"Universit\u00e9 de Caen Normandie","ror":"https://ror.org/051kpcy16","country_code":"FR","type":"education","lineage":["https://openalex.org/I4210105918","https://openalex.org/I98702875"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Marc-Olivier Fischer","raw_affiliation_strings":["Department of Anesthesiology-Resuscitation and Perioperative Medicine, Normandy University, UNICAEN, Caen University Hospital, Normandy, Caen, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Anesthesiology-Resuscitation and Perioperative Medicine, Normandy University, UNICAEN, Caen University Hospital, Normandy, Caen, France","institution_ids":["https://openalex.org/I4210114068","https://openalex.org/I98702875"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":6,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.9798,"has_fulltext":false,"cited_by_count":26,"citation_normalized_percentile":{"value":0.89229397,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"48","issue":"10","first_page":"1454","last_page":"1461"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10322","display_name":"Respiratory Support and Mechanisms","score":0.9740999937057495,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10322","display_name":"Respiratory Support and Mechanisms","score":0.9740999937057495,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11700","display_name":"Hemodynamic Monitoring and Therapy","score":0.007799999788403511,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10218","display_name":"Sepsis Diagnosis and Treatment","score":0.006300000008195639,"subfield":{"id":"https://openalex.org/subfields/2706","display_name":"Critical Care and Intensive Care Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/extubation-failure","display_name":"extubation failure","score":0.9929999709129333},{"id":"https://openalex.org/keywords/central-venous-oxygen-saturation","display_name":"central venous oxygen saturation","score":0.9940000176429749},{"id":"https://openalex.org/keywords/spontaneous-breathing-trial","display_name":"spontaneous breathing trial","score":0.8759999871253967},{"id":"https://openalex.org/keywords/weaning-from-mechanical-ventilation","display_name":"weaning from mechanical ventilation","score":0.8299999833106995},{"id":"https://openalex.org/keywords/oxygen-extraction","display_name":"oxygen extraction","score":0.7900000214576721},{"id":"https://openalex.org/keywords/oxygen-delivery-index","display_name":"oxygen delivery index","score":0.9639999866485596},{"id":"https://openalex.org/keywords/critically-ill-patients","display_name":"critically ill patients","score":0.8330000042915344},{"id":"https://openalex.org/keywords/weaning-prediction","display_name":"weaning prediction","score":0.4480000138282776},{"id":"https://openalex.org/keywords/weaning-success","display_name":"weaning success","score":0.4300000071525574}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.883541464805603},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.6441881656646729},{"id":"https://openalex.org/C2777080012","wikidata":"https://www.wikidata.org/wiki/Q3766250","display_name":"Mechanical ventilation","level":2,"score":0.609356164932251},{"id":"https://openalex.org/C2778584172","wikidata":"https://www.wikidata.org/wiki/Q7579051","display_name":"Spontaneous breathing trial","level":3,"score":0.5327560901641846},{"id":"https://openalex.org/C35207712","wikidata":"https://www.wikidata.org/wiki/Q190402","display_name":"Central venous pressure","level":4,"score":0.5019779205322266},{"id":"https://openalex.org/C76538665","wikidata":"https://www.wikidata.org/wiki/Q6294669","display_name":"Oxygen saturation","level":3,"score":0.46672549843788147},{"id":"https://openalex.org/C200457457","wikidata":"https://www.wikidata.org/wiki/Q584049","display_name":"Ventilation (architecture)","level":2,"score":0.4279133081436157},{"id":"https://openalex.org/C31861589","wikidata":"https://www.wikidata.org/wiki/Q618068","display_name":"Cardiac index","level":4,"score":0.42112934589385986},{"id":"https://openalex.org/C540031477","wikidata":"https://www.wikidata.org/wiki/Q629","display_name":"Oxygen","level":2,"score":0.39598673582077026},{"id":"https://openalex.org/C178853913","wikidata":"https://www.wikidata.org/wiki/Q1642137","display_name":"Hemodynamics","level":2,"score":0.29516127705574036},{"id":"https://openalex.org/C139940330","wikidata":"https://www.wikidata.org/wiki/Q596579","display_name":"Cardiac output","level":3,"score":0.27297496795654297},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.2555305063724518},{"id":"https://openalex.org/C84393581","wikidata":"https://www.wikidata.org/wiki/Q82642","display_name":"Blood pressure","level":2,"score":0.2412419319152832},{"id":"https://openalex.org/C2777953023","wikidata":"https://www.wikidata.org/wiki/Q1073121","display_name":"Heart rate","level":3,"score":0.1328195333480835},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.0},{"id":"https://openalex.org/C78519656","wikidata":"https://www.wikidata.org/wiki/Q101333","display_name":"Mechanical engineering","level":1,"score":0.0},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001784","descriptor_name":"Blood Gas Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002245","descriptor_name":"Carbon Dioxide","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D002985","descriptor_name":"Clinical Protocols","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006439","descriptor_name":"Hemodynamics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007362","descriptor_name":"Intensive Care Units","qualifier_ui":"Q000706","qualifier_name":"statistics & numerical data","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010100","descriptor_name":"Oxygen","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D010101","descriptor_name":"Oxygen Consumption","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011446","descriptor_name":"Prospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012121","descriptor_name":"Respiration, Artificial","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015300","descriptor_name":"Ventilator Weaning","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D015656","descriptor_name":"Respiratory Mechanics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016638","descriptor_name":"Critical Illness","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D060666","descriptor_name":"Airway Extubation","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1097/ccm.0000000000004446","doi":"https://doi.org/10.1097/ccm.0000000000004446","is_oa":false,"landing_page_url":"https://doi.org/10.1097/ccm.0000000000004446","pdf_url":null,"source":{"id":"https://openalex.org/S108732581","display_name":"Critical Care Medicine","issn_l":"0090-3493","issn":["0090-3493","1530-0293"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Critical Care Medicine","raw_type":"journal-article"},{"id":"pmid:32520890","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/32520890","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Critical care medicine","raw_type":"Journal Article"},{"id":"pmh:oai:HAL:hal-05154783v1","doi":null,"is_oa":false,"landing_page_url":"https://hal.science/hal-05154783","pdf_url":null,"source":{"id":"https://openalex.org/S4306402512","display_name":"HAL","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4405252976","host_organization_name":"Centre pour la Communication Scientifique Directe","host_organization_lineage":["https://openalex.org/I4405252976"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Critical Care Medicine, 2020, 48 (10), pp.1454-1461. ⟨10.1097/CCM.0000000000004446⟩","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9940000176429749}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":34,"referenced_works":["https://openalex.org/W64653452","https://openalex.org/W1872567087","https://openalex.org/W1970799063","https://openalex.org/W1971030408","https://openalex.org/W1978958680","https://openalex.org/W1992977793","https://openalex.org/W2027072572","https://openalex.org/W2028841156","https://openalex.org/W2032612415","https://openalex.org/W2033051147","https://openalex.org/W2041468256","https://openalex.org/W2057736164","https://openalex.org/W2073079549","https://openalex.org/W2075135285","https://openalex.org/W2079164465","https://openalex.org/W2080564894","https://openalex.org/W2082384979","https://openalex.org/W2087919076","https://openalex.org/W2100987303","https://openalex.org/W2131063389","https://openalex.org/W2140771005","https://openalex.org/W2142104245","https://openalex.org/W2158586592","https://openalex.org/W2172458312","https://openalex.org/W2180690155","https://openalex.org/W2270732430","https://openalex.org/W2328176404","https://openalex.org/W2414032260","https://openalex.org/W2768401680","https://openalex.org/W2922125865","https://openalex.org/W2951997665","https://openalex.org/W2961918293","https://openalex.org/W2978081422","https://openalex.org/W2978470254"],"related_works":["https://openalex.org/W7165015334","https://openalex.org/W4388190861","https://openalex.org/W4241883466","https://openalex.org/W4409306136","https://openalex.org/W6967602243","https://openalex.org/W2028841156","https://openalex.org/W4384521250","https://openalex.org/W6977093261","https://openalex.org/W1980095868","https://openalex.org/W3028179381"],"abstract_inverted_index":{"OBJECTIVES:":[0],"To":[1],"evaluate":[2],"the":[3,17,74,145,162,171,183,189,199,206,269,281],"ability":[4],"of":[5,19,271,306,311],"central":[6,12,93,97,219,258,295],"venous-to-arterial":[7,98],"carbon":[8,99],"dioxide":[9,100],"pressure":[10,101],"difference,":[11,102],"venous":[13,94,178,220,259,296],"oxygen":[14,87,90,95,104,179,221,260,297],"saturation,":[15,96,298],"and":[16,51,103,113,126,155,168,186,203,218,243,257,273,294,318],"combination":[18],"these":[20],"two":[21],"parameters":[22,313],"to":[23],"detect":[24],"extubation":[25,127,200,232,264,323],"failure":[26,70,128,146,156,163,184,201,233,265,324],"in":[27,131,144,152,161,170,182,188,198,205,213,322,326],"critically":[28,327],"ill":[29,328],"patients.":[30,134,329],"DESIGN:":[31],"Multicentric,":[32],"prospective,":[33],"observational":[34],"study.":[35],"SETTING:":[36],"Three":[37],"ICUs.":[38],"PATIENTS:":[39],"All":[40],"patients":[41,123],"who":[42],"received":[43],"mechanical":[44,77],"ventilation":[45,78],"for":[46,59,76],"more":[47],"than":[48],"48":[49,80],"hours":[50],"tolerated":[52],"spontaneous":[53,66,110,118,141,225,300],"breathing":[54,67,111,119,142,226,301],"trials":[55,112,120,143,227],"with":[56,231,266],"a":[57],"T-piece":[58],"60":[60,115],"minutes.":[61],"INTERVENTIONS:":[62],"Extubation":[63,69],"after":[64,117],"successful":[65],"trials.":[68],"was":[71,129,283],"defined":[72],"as":[73],"need":[75],"within":[79],"hours.":[81],"MEASUREMENTS":[82],"AND":[83],"MAIN":[84],"RESULTS:":[85],"The":[86],"delivery":[88,149],"index,":[89,92],"consumption":[91,136],"extraction":[105,159],"were":[106,124,228,303],"measured":[107],"immediately":[108],"before":[109],"at":[114,285],"minutes":[116],"initiation.":[121],"Seventy-five":[122],"enrolled,":[125],"noted":[130],"18":[132],"(24%)":[133],"Oxygen":[135,148,158],"index":[137,150],"increased":[138,151,160,187,197],"significantly":[139],"during":[140,224,299],"group.":[147],"both":[153,312],"success":[154,172,190,207],"groups.":[157],"group":[164,173,185,191,202,208],"(p":[165,174,192,209],"=":[166,175,193,210,241,251],"0.005)":[167],"decreased":[169,181,204],"0.001).":[176],"Central":[177],"saturation":[180,222,261],"0.014).":[194],"\u0394PCO2":[195,214,256,293],"value":[196],"0.002).":[211],"Changes":[212],"(\u0394":[215],"-":[216,255,292],"\u0394PCO2)":[217],"(\u0394ScvO2)":[223],"independently":[229],"associated":[230],"(odds":[234],"ratio,":[235,245],"1.02;":[236],"95%":[237,247],"CI,":[238,248],"1.01-1.05;":[239],"p":[240,250],"0.006,":[242],"odds":[244],"0.84;":[246],"0.70-0.95;":[249],"0.02,":[252],"respectively).":[253],"\u0394":[254,291],"could":[262],"predict":[263],"areas":[267,279],"under":[268,280],"curve":[270,282],"0.865":[272],"0.856,":[274],"respectively;":[275],"however,":[276],"their":[277,315],"combined":[278],"better":[284],"0.940.":[286],"CONCLUSIONS:":[287],"We":[288],"found":[289],"that":[290],"trials,":[302],"independent":[304],"predictors":[305],"weaning":[307],"outcomes.":[308],"Combination":[309],"analysis":[310],"enhanced":[314],"diagnostic":[316],"performance":[317],"provided":[319],"excellent":[320],"predictability":[321],"detection":[325]},"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":4},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":10},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2020-06-12T00:00:00"}