{"id":"https://openalex.org/W3032736679","doi":"https://doi.org/10.1007/s10544-020-00495-3","title":"Covalent immobilization of luminescent oxygen indicators reduces cytotoxicity","display_name":"Covalent immobilization of luminescent oxygen indicators reduces cytotoxicity","publication_year":2020,"publication_date":"2020-06-01","ids":{"openalex":"https://openalex.org/W3032736679","doi":"https://doi.org/10.1007/s10544-020-00495-3","mag":"3032736679","pmid":"https://pubmed.ncbi.nlm.nih.gov/32494857","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/7270993"},"language":"en","primary_location":{"id":"doi:10.1007/s10544-020-00495-3","doi":"https://doi.org/10.1007/s10544-020-00495-3","is_oa":true,"landing_page_url":"https://doi.org/10.1007/s10544-020-00495-3","pdf_url":"https://link.springer.com/content/pdf/10.1007/s10544-020-00495-3.pdf","source":{"id":"https://openalex.org/S173545647","display_name":"Biomedical Microdevices","issn_l":"1387-2176","issn":["1387-2176","1572-8781"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biomedical Microdevices","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://link.springer.com/content/pdf/10.1007/s10544-020-00495-3.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5031669192","display_name":"Hannu V\u00e4lim\u00e4ki","orcid":"https://orcid.org/0000-0002-9611-1711","observed_orcids":["https://orcid.org/0000-0002-9611-1711"]},"institutions":[{"id":"https://openalex.org/I166825849","display_name":"Tampere University","ror":"https://ror.org/033003e23","country_code":"FI","type":"education","lineage":["https://openalex.org/I166825849"]},{"id":"https://openalex.org/I4387153886","display_name":"University of Tampere","ror":"https://ror.org/05p6qqk79","country_code":"FI","type":"education","lineage":["https://openalex.org/I166825849","https://openalex.org/I4387153886"]}],"countries":["FI"],"is_corresponding":true,"raw_author_name":"Hannu V\u00e4lim\u00e4ki","raw_affiliation_strings":["Faculty of Medicine and Health Technology, Tampere University, Korkeakoulunkatu 3, 33720, Tampere, Finland. hannu.valimaki@tuni.fi","Faculty of Medicine and Health Technology, Tampere University, Korkeakoulunkatu 3, 33720, Tampere, Finland"],"raw_orcid":"https://orcid.org/0000-0002-9611-1711","affiliations":[{"raw_affiliation_string":"Faculty of Medicine and Health Technology, Tampere University, Korkeakoulunkatu 3, 33720, Tampere, Finland. hannu.valimaki@tuni.fi","institution_ids":["https://openalex.org/I166825849","https://openalex.org/I4387153886"]},{"raw_affiliation_string":"Faculty of Medicine and Health Technology, Tampere University, Korkeakoulunkatu 3, 33720, Tampere, Finland","institution_ids":["https://openalex.org/I166825849","https://openalex.org/I4387153886"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083055605","display_name":"Tanja Hyv\u00e4rinen","orcid":"https://orcid.org/0000-0002-8723-8817","observed_orcids":["https://orcid.org/0000-0002-8723-8817"]},"institutions":[{"id":"https://openalex.org/I166825849","display_name":"Tampere University","ror":"https://ror.org/033003e23","country_code":"FI","type":"education","lineage":["https://openalex.org/I166825849"]},{"id":"https://openalex.org/I4387153886","display_name":"University of Tampere","ror":"https://ror.org/05p6qqk79","country_code":"FI","type":"education","lineage":["https://openalex.org/I166825849","https://openalex.org/I4387153886"]}],"countries":["FI"],"is_corresponding":false,"raw_author_name":"Tanja Hyv\u00e4rinen","raw_affiliation_strings":["Faculty of Medicine and Health Technology, Tampere University, Arvo Ylp\u00f6n katu 34, 33520, Tampere, Finland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Medicine and Health Technology, Tampere University, Arvo Ylp\u00f6n katu 34, 33520, Tampere, Finland","institution_ids":["https://openalex.org/I166825849","https://openalex.org/I4387153886"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013144142","display_name":"Joni Leivo","orcid":"https://orcid.org/0000-0002-7137-5948","observed_orcids":["https://orcid.org/0000-0002-7137-5948"]},"institutions":[{"id":"https://openalex.org/I166825849","display_name":"Tampere University","ror":"https://ror.org/033003e23","country_code":"FI","type":"education","lineage":["https://openalex.org/I166825849"]},{"id":"https://openalex.org/I4387153886","display_name":"University of Tampere","ror":"https://ror.org/05p6qqk79","country_code":"FI","type":"education","lineage":["https://openalex.org/I166825849","https://openalex.org/I4387153886"]}],"countries":["FI"],"is_corresponding":false,"raw_author_name":"Joni Leivo","raw_affiliation_strings":["Faculty of Medicine and Health Technology, Tampere University, Korkeakoulunkatu 3, 33720, Tampere, Finland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Medicine and Health Technology, Tampere University, Korkeakoulunkatu 3, 33720, Tampere, Finland","institution_ids":["https://openalex.org/I166825849","https://openalex.org/I4387153886"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029969288","display_name":"Haider Iftikhar","orcid":"https://orcid.org/0009-0006-8893-0588","observed_orcids":["https://orcid.org/0009-0006-8893-0588"]},"institutions":[{"id":"https://openalex.org/I166825849","display_name":"Tampere University","ror":"https://ror.org/033003e23","country_code":"FI","type":"education","lineage":["https://openalex.org/I166825849"]},{"id":"https://openalex.org/I4387153886","display_name":"University of Tampere","ror":"https://ror.org/05p6qqk79","country_code":"FI","type":"education","lineage":["https://openalex.org/I166825849","https://openalex.org/I4387153886"]}],"countries":["FI"],"is_corresponding":false,"raw_author_name":"Haider Iftikhar","raw_affiliation_strings":["Faculty of Medicine and Health Technology, Tampere University, Korkeakoulunkatu 3, 33720, Tampere, Finland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Medicine and Health Technology, Tampere University, Korkeakoulunkatu 3, 33720, Tampere, Finland","institution_ids":["https://openalex.org/I166825849","https://openalex.org/I4387153886"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029982992","display_name":"Mari Pekkanen-Mattila","orcid":"https://orcid.org/0000-0002-8621-4303","observed_orcids":["https://orcid.org/0000-0002-8621-4303"]},"institutions":[{"id":"https://openalex.org/I166825849","display_name":"Tampere University","ror":"https://ror.org/033003e23","country_code":"FI","type":"education","lineage":["https://openalex.org/I166825849"]},{"id":"https://openalex.org/I4387153886","display_name":"University of Tampere","ror":"https://ror.org/05p6qqk79","country_code":"FI","type":"education","lineage":["https://openalex.org/I166825849","https://openalex.org/I4387153886"]}],"countries":["FI"],"is_corresponding":false,"raw_author_name":"Mari Pekkanen-Mattila","raw_affiliation_strings":["Faculty of Medicine and Health Technology, Tampere University, Arvo Ylp\u00f6n katu 34, 33520, Tampere, Finland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Medicine and Health Technology, Tampere University, Arvo Ylp\u00f6n katu 34, 33520, Tampere, Finland","institution_ids":["https://openalex.org/I166825849","https://openalex.org/I4387153886"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043502027","display_name":"Dhanesh Kattipparambil Rajan","orcid":"https://orcid.org/0000-0001-9210-9481","observed_orcids":["https://orcid.org/0000-0001-9210-9481"]},"institutions":[{"id":"https://openalex.org/I166825849","display_name":"Tampere University","ror":"https://ror.org/033003e23","country_code":"FI","type":"education","lineage":["https://openalex.org/I166825849"]},{"id":"https://openalex.org/I4387153886","display_name":"University of Tampere","ror":"https://ror.org/05p6qqk79","country_code":"FI","type":"education","lineage":["https://openalex.org/I166825849","https://openalex.org/I4387153886"]}],"countries":["FI"],"is_corresponding":false,"raw_author_name":"Dhanesh Kattipparambil Rajan","raw_affiliation_strings":["Faculty of Medicine and Health Technology, Tampere University, Korkeakoulunkatu 3, 33720, Tampere, Finland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Medicine and Health Technology, Tampere University, Korkeakoulunkatu 3, 33720, Tampere, Finland","institution_ids":["https://openalex.org/I166825849","https://openalex.org/I4387153886"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051757454","display_name":"Jarmo A. Verho","orcid":"https://orcid.org/0000-0002-8272-4760","observed_orcids":["https://orcid.org/0000-0002-8272-4760"]},"institutions":[{"id":"https://openalex.org/I166825849","display_name":"Tampere University","ror":"https://ror.org/033003e23","country_code":"FI","type":"education","lineage":["https://openalex.org/I166825849"]},{"id":"https://openalex.org/I4387153886","display_name":"University of Tampere","ror":"https://ror.org/05p6qqk79","country_code":"FI","type":"education","lineage":["https://openalex.org/I166825849","https://openalex.org/I4387153886"]}],"countries":["FI"],"is_corresponding":false,"raw_author_name":"Jarmo Verho","raw_affiliation_strings":["Faculty of Medicine and Health Technology, Tampere University, Korkeakoulunkatu 3, 33720, Tampere, Finland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Medicine and Health Technology, Tampere University, Korkeakoulunkatu 3, 33720, Tampere, Finland","institution_ids":["https://openalex.org/I166825849","https://openalex.org/I4387153886"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031874991","display_name":"Joose Kreutzer","orcid":"https://orcid.org/0000-0001-5964-8707","observed_orcids":["https://orcid.org/0000-0001-5964-8707"]},"institutions":[{"id":"https://openalex.org/I166825849","display_name":"Tampere University","ror":"https://ror.org/033003e23","country_code":"FI","type":"education","lineage":["https://openalex.org/I166825849"]},{"id":"https://openalex.org/I4387153886","display_name":"University of Tampere","ror":"https://ror.org/05p6qqk79","country_code":"FI","type":"education","lineage":["https://openalex.org/I166825849","https://openalex.org/I4387153886"]}],"countries":["FI"],"is_corresponding":false,"raw_author_name":"Joose Kreutzer","raw_affiliation_strings":["Faculty of Medicine and Health Technology, Tampere University, Korkeakoulunkatu 3, 33720, Tampere, Finland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Medicine and Health Technology, Tampere University, Korkeakoulunkatu 3, 33720, Tampere, Finland","institution_ids":["https://openalex.org/I166825849","https://openalex.org/I4387153886"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052745471","display_name":"Tomi Ryyn\u00e4nen","orcid":"https://orcid.org/0000-0001-7424-1841","observed_orcids":["https://orcid.org/0000-0001-7424-1841"]},"institutions":[{"id":"https://openalex.org/I166825849","display_name":"Tampere University","ror":"https://ror.org/033003e23","country_code":"FI","type":"education","lineage":["https://openalex.org/I166825849"]},{"id":"https://openalex.org/I4387153886","display_name":"University of Tampere","ror":"https://ror.org/05p6qqk79","country_code":"FI","type":"education","lineage":["https://openalex.org/I166825849","https://openalex.org/I4387153886"]}],"countries":["FI"],"is_corresponding":false,"raw_author_name":"Tomi Ryyn\u00e4nen","raw_affiliation_strings":["Faculty of Medicine and Health Technology, Tampere University, Korkeakoulunkatu 3, 33720, Tampere, Finland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Medicine and Health Technology, Tampere University, Korkeakoulunkatu 3, 33720, Tampere, Finland","institution_ids":["https://openalex.org/I166825849","https://openalex.org/I4387153886"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016362162","display_name":"Jonatan Pirhonen","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I166825849","display_name":"Tampere University","ror":"https://ror.org/033003e23","country_code":"FI","type":"education","lineage":["https://openalex.org/I166825849"]},{"id":"https://openalex.org/I4387153886","display_name":"University of Tampere","ror":"https://ror.org/05p6qqk79","country_code":"FI","type":"education","lineage":["https://openalex.org/I166825849","https://openalex.org/I4387153886"]}],"countries":["FI"],"is_corresponding":false,"raw_author_name":"Jonatan Pirhonen","raw_affiliation_strings":["Faculty of Medicine and Health Technology, Tampere University, Arvo Ylp\u00f6n katu 34, 33520, Tampere, Finland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Medicine and Health Technology, Tampere University, Arvo Ylp\u00f6n katu 34, 33520, Tampere, Finland","institution_ids":["https://openalex.org/I166825849","https://openalex.org/I4387153886"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027482380","display_name":"Katriina Aalto\u2010Set\u00e4l\u00e4","orcid":"https://orcid.org/0000-0003-0334-2172","observed_orcids":["https://orcid.org/0000-0003-0334-2172"]},"institutions":[{"id":"https://openalex.org/I166825849","display_name":"Tampere University","ror":"https://ror.org/033003e23","country_code":"FI","type":"education","lineage":["https://openalex.org/I166825849"]},{"id":"https://openalex.org/I4387153886","display_name":"University of Tampere","ror":"https://ror.org/05p6qqk79","country_code":"FI","type":"education","lineage":["https://openalex.org/I166825849","https://openalex.org/I4387153886"]}],"countries":["FI"],"is_corresponding":false,"raw_author_name":"Katriina Aalto-Set\u00e4l\u00e4","raw_affiliation_strings":["Faculty of Medicine and Health Technology, Tampere University, Arvo Ylp\u00f6n katu 34, 33520, Tampere, Finland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Medicine and Health Technology, Tampere University, Arvo Ylp\u00f6n katu 34, 33520, Tampere, Finland","institution_ids":["https://openalex.org/I166825849","https://openalex.org/I4387153886"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082951245","display_name":"Pasi J. Kallio","orcid":"https://orcid.org/0000-0002-2890-6782","observed_orcids":["https://orcid.org/0000-0002-2890-6782"]},"institutions":[{"id":"https://openalex.org/I166825849","display_name":"Tampere University","ror":"https://ror.org/033003e23","country_code":"FI","type":"education","lineage":["https://openalex.org/I166825849"]},{"id":"https://openalex.org/I4387153886","display_name":"University of Tampere","ror":"https://ror.org/05p6qqk79","country_code":"FI","type":"education","lineage":["https://openalex.org/I166825849","https://openalex.org/I4387153886"]}],"countries":["FI"],"is_corresponding":false,"raw_author_name":"Pasi Kallio","raw_affiliation_strings":["Faculty of Medicine and Health Technology, Tampere University, Korkeakoulunkatu 3, 33720, Tampere, Finland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Medicine and Health Technology, Tampere University, Korkeakoulunkatu 3, 33720, Tampere, Finland","institution_ids":["https://openalex.org/I166825849","https://openalex.org/I4387153886"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071010026","display_name":"Susanna Narkilahti","orcid":"https://orcid.org/0000-0002-7602-4418","observed_orcids":["https://orcid.org/0000-0002-7602-4418"]},"institutions":[{"id":"https://openalex.org/I166825849","display_name":"Tampere University","ror":"https://ror.org/033003e23","country_code":"FI","type":"education","lineage":["https://openalex.org/I166825849"]},{"id":"https://openalex.org/I4387153886","display_name":"University of Tampere","ror":"https://ror.org/05p6qqk79","country_code":"FI","type":"education","lineage":["https://openalex.org/I166825849","https://openalex.org/I4387153886"]}],"countries":["FI"],"is_corresponding":false,"raw_author_name":"Susanna Narkilahti","raw_affiliation_strings":["Faculty of Medicine and Health Technology, Tampere University, Arvo Ylp\u00f6n katu 34, 33520, Tampere, Finland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Medicine and Health Technology, Tampere University, Arvo Ylp\u00f6n katu 34, 33520, Tampere, Finland","institution_ids":["https://openalex.org/I166825849","https://openalex.org/I4387153886"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5010105730","display_name":"Jukka O. Lekkala","orcid":"https://orcid.org/0000-0001-9293-2240","observed_orcids":["https://orcid.org/0000-0001-9293-2240"]},"institutions":[{"id":"https://openalex.org/I166825849","display_name":"Tampere University","ror":"https://ror.org/033003e23","country_code":"FI","type":"education","lineage":["https://openalex.org/I166825849"]},{"id":"https://openalex.org/I4387153886","display_name":"University of Tampere","ror":"https://ror.org/05p6qqk79","country_code":"FI","type":"education","lineage":["https://openalex.org/I166825849","https://openalex.org/I4387153886"]}],"countries":["FI"],"is_corresponding":false,"raw_author_name":"Jukka Lekkala","raw_affiliation_strings":["Faculty of Medicine and Health Technology, Tampere University, Korkeakoulunkatu 3, 33720, Tampere, Finland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Medicine and Health Technology, Tampere University, Korkeakoulunkatu 3, 33720, Tampere, Finland","institution_ids":["https://openalex.org/I166825849","https://openalex.org/I4387153886"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5031669192"],"corresponding_institution_ids":["https://openalex.org/I166825849","https://openalex.org/I4387153886"],"apc_list":{"value":3260,"currency":"USD","value_usd":3260},"apc_paid":{"value":3260,"currency":"USD","value_usd":3260},"fwci":0.4877,"has_fulltext":true,"cited_by_count":9,"citation_normalized_percentile":{"value":0.4871409,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":97},"biblio":{"volume":"22","issue":"2","first_page":"41","last_page":"41"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11472","display_name":"Analytical Chemistry and Sensors","score":0.9603999853134155,"subfield":{"id":"https://openalex.org/subfields/1602","display_name":"Analytical Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T11472","display_name":"Analytical Chemistry and Sensors","score":0.9603999853134155,"subfield":{"id":"https://openalex.org/subfields/1602","display_name":"Analytical Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10532","display_name":"Molecular Sensors and Ion Detection","score":0.00930000003427267,"subfield":{"id":"https://openalex.org/subfields/1607","display_name":"Spectroscopy"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12264","display_name":"Tissue Engineering and Regenerative Medicine","score":0.00430000014603138,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/covalent-immobilization","display_name":"covalent immobilization","score":0.8999999761581421},{"id":"https://openalex.org/keywords/platinum-porphyrin","display_name":"platinum porphyrin","score":0.7670000195503235},{"id":"https://openalex.org/keywords/pttfpp","display_name":"PtTFPP","score":0.7979999780654907},{"id":"https://openalex.org/keywords/cytotoxicity","display_name":"cytotoxicity","score":0.9829999804496765},{"id":"https://openalex.org/keywords/polystyrene","display_name":"polystyrene","score":0.7009999752044678},{"id":"https://openalex.org/keywords/oxygen-sensing","display_name":"oxygen sensing","score":0.625},{"id":"https://openalex.org/keywords/hypoxia","display_name":"hypoxia","score":0.9430000185966492},{"id":"https://openalex.org/keywords/hipsc-derived-cardiomyocytes","display_name":"hiPSC-derived cardiomyocytes","score":0.9380000233650208},{"id":"https://openalex.org/keywords/hipsc-derived-neurons","display_name":"hiPSC-derived neurons","score":0.9449999928474426},{"id":"https://openalex.org/keywords/cell-viability","display_name":"cell viability","score":0.7459999918937683}],"concepts":[{"id":"https://openalex.org/C180577832","wikidata":"https://www.wikidata.org/wiki/Q127920","display_name":"Covalent bond","level":2,"score":0.8531317710876465},{"id":"https://openalex.org/C540031477","wikidata":"https://www.wikidata.org/wiki/Q629","display_name":"Oxygen","level":2,"score":0.669367790222168},{"id":"https://openalex.org/C109316439","wikidata":"https://www.wikidata.org/wiki/Q246181","display_name":"Cytotoxicity","level":3,"score":0.646124005317688},{"id":"https://openalex.org/C17734536","wikidata":"https://www.wikidata.org/wiki/Q286588","display_name":"Oxygen sensor","level":3,"score":0.5529520511627197},{"id":"https://openalex.org/C90982505","wikidata":"https://www.wikidata.org/wiki/Q16938886","display_name":"Leaching (pedology)","level":3,"score":0.5224282145500183},{"id":"https://openalex.org/C148869448","wikidata":"https://www.wikidata.org/wiki/Q184240","display_name":"Luminescence","level":2,"score":0.5079239010810852},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.4638056755065918},{"id":"https://openalex.org/C2777922577","wikidata":"https://www.wikidata.org/wiki/Q146243","display_name":"Polystyrene","level":3,"score":0.4541071057319641},{"id":"https://openalex.org/C2779480358","wikidata":"https://www.wikidata.org/wiki/Q422926","display_name":"Porphyrin","level":2,"score":0.4437094032764435},{"id":"https://openalex.org/C521977710","wikidata":"https://www.wikidata.org/wiki/Q81163","display_name":"Polymer","level":2,"score":0.44367551803588867},{"id":"https://openalex.org/C106487976","wikidata":"https://www.wikidata.org/wiki/Q685816","display_name":"Matrix (chemical analysis)","level":2,"score":0.42763128876686096},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.41619056463241577},{"id":"https://openalex.org/C42360764","wikidata":"https://www.wikidata.org/wiki/Q83588","display_name":"Chemical engineering","level":1,"score":0.3856794238090515},{"id":"https://openalex.org/C21951064","wikidata":"https://www.wikidata.org/wiki/Q899212","display_name":"Combinatorial chemistry","level":1,"score":0.3217698335647583},{"id":"https://openalex.org/C75473681","wikidata":"https://www.wikidata.org/wiki/Q188651","display_name":"Photochemistry","level":1,"score":0.23694908618927002},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.22035735845565796},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.20427897572517395},{"id":"https://openalex.org/C39432304","wikidata":"https://www.wikidata.org/wiki/Q188847","display_name":"Environmental science","level":0,"score":0.08247467875480652},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0674823522567749},{"id":"https://openalex.org/C49040817","wikidata":"https://www.wikidata.org/wiki/Q193091","display_name":"Optoelectronics","level":1,"score":0.06531339883804321},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.0},{"id":"https://openalex.org/C159750122","wikidata":"https://www.wikidata.org/wiki/Q96621023","display_name":"Soil water","level":2,"score":0.0},{"id":"https://openalex.org/C159390177","wikidata":"https://www.wikidata.org/wiki/Q9161265","display_name":"Soil science","level":1,"score":0.0},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D009474","descriptor_name":"Neurons","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D009474","descriptor_name":"Neurons","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D010100","descriptor_name":"Oxygen","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":true},{"descriptor_ui":"D011166","descriptor_name":"Porphyrins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D032383","descriptor_name":"Myocytes, Cardiac","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D032383","descriptor_name":"Myocytes, Cardiac","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D049408","descriptor_name":"Luminescent Agents","qualifier_ui":"Q000633","qualifier_name":"toxicity","is_major_topic":true},{"descriptor_ui":"D049408","descriptor_name":"Luminescent Agents","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D057026","descriptor_name":"Induced Pluripotent Stem Cells","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1007/s10544-020-00495-3","doi":"https://doi.org/10.1007/s10544-020-00495-3","is_oa":true,"landing_page_url":"https://doi.org/10.1007/s10544-020-00495-3","pdf_url":"https://link.springer.com/content/pdf/10.1007/s10544-020-00495-3.pdf","source":{"id":"https://openalex.org/S173545647","display_name":"Biomedical Microdevices","issn_l":"1387-2176","issn":["1387-2176","1572-8781"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biomedical Microdevices","raw_type":"journal-article"},{"id":"pmid:32494857","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/32494857","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biomedical microdevices","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:7270993","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC7270993/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biomed Microdevices","raw_type":"Text"},{"id":"pmh:oai:trepo.tuni.fi:10024/217425","doi":null,"is_oa":true,"landing_page_url":"https://trepo.tuni.fi/handle/10024/217425","pdf_url":null,"source":{"id":"https://openalex.org/S4306401860","display_name":"Tampere University Institutional Repository (Tampere University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I150589677","host_organization_name":"Tampere University of Applied Sciences","host_organization_lineage":["https://openalex.org/I150589677"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"publishedVersion"}],"best_oa_location":{"id":"doi:10.1007/s10544-020-00495-3","doi":"https://doi.org/10.1007/s10544-020-00495-3","is_oa":true,"landing_page_url":"https://doi.org/10.1007/s10544-020-00495-3","pdf_url":"https://link.springer.com/content/pdf/10.1007/s10544-020-00495-3.pdf","source":{"id":"https://openalex.org/S173545647","display_name":"Biomedical Microdevices","issn_l":"1387-2176","issn":["1387-2176","1572-8781"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biomedical Microdevices","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.504800021648407}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1030840209","display_name":null,"funder_award_id":"311022","funder_id":"https://openalex.org/F4320321108","funder_display_name":"Academy of Finland"},{"id":"https://openalex.org/G2443355962","display_name":null,"funder_award_id":"40332/14","funder_id":"https://openalex.org/F4320321855","funder_display_name":"Tekes"},{"id":"https://openalex.org/G2677833538","display_name":null,"funder_award_id":"311017,311021,311022","funder_id":"https://openalex.org/F4320321108","funder_display_name":"Academy of Finland"},{"id":"https://openalex.org/G5452677992","display_name":null,"funder_award_id":"311017","funder_id":"https://openalex.org/F4320321108","funder_display_name":"Academy of Finland"},{"id":"https://openalex.org/G7310953183","display_name":null,"funder_award_id":"311021","funder_id":"https://openalex.org/F4320321108","funder_display_name":"Academy of Finland"}],"funders":[{"id":"https://openalex.org/F4320321108","display_name":"Academy of Finland","ror":"https://ror.org/05k73zm37"},{"id":"https://openalex.org/F4320321855","display_name":"Tekes","ror":"https://ror.org/02ag8cq23"},{"id":"https://openalex.org/F4320328501","display_name":"Business Finland","ror":"https://ror.org/05bgf9v38"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3032736679.pdf","grobid_xml":"https://content.openalex.org/works/W3032736679.grobid-xml"},"referenced_works_count":49,"referenced_works":["https://openalex.org/W1522450221","https://openalex.org/W1978095629","https://openalex.org/W1987619085","https://openalex.org/W1995629728","https://openalex.org/W1996085840","https://openalex.org/W1996163778","https://openalex.org/W2016188652","https://openalex.org/W2019825048","https://openalex.org/W2023049557","https://openalex.org/W2023652080","https://openalex.org/W2038232799","https://openalex.org/W2041681560","https://openalex.org/W2061928182","https://openalex.org/W2064632152","https://openalex.org/W2065863985","https://openalex.org/W2072198755","https://openalex.org/W2079340323","https://openalex.org/W2080992953","https://openalex.org/W2087914987","https://openalex.org/W2090436932","https://openalex.org/W2091360640","https://openalex.org/W2093398126","https://openalex.org/W2100903105","https://openalex.org/W2107554012","https://openalex.org/W2111794549","https://openalex.org/W2115637125","https://openalex.org/W2122202120","https://openalex.org/W2123640755","https://openalex.org/W2129995310","https://openalex.org/W2130933110","https://openalex.org/W2136125227","https://openalex.org/W2139442812","https://openalex.org/W2148598311","https://openalex.org/W2151734986","https://openalex.org/W2152635048","https://openalex.org/W2161039998","https://openalex.org/W2161741964","https://openalex.org/W2324430022","https://openalex.org/W2491458126","https://openalex.org/W2521650734","https://openalex.org/W2608500514","https://openalex.org/W2776970920","https://openalex.org/W2790463643","https://openalex.org/W2791298228","https://openalex.org/W2801378456","https://openalex.org/W2883854607","https://openalex.org/W2896198442","https://openalex.org/W2980721728","https://openalex.org/W4391626143"],"related_works":["https://openalex.org/W1988288291","https://openalex.org/W2093398126","https://openalex.org/W2801274630","https://openalex.org/W1993235550","https://openalex.org/W2428755824","https://openalex.org/W2092678502","https://openalex.org/W2047060124","https://openalex.org/W2095258722","https://openalex.org/W1979071993","https://openalex.org/W2041681560"],"abstract_inverted_index":{"Luminescence-based":[0],"oxygen":[1,18,77,137,153,159,187,195],"sensing":[2,99,138,154,188,196],"is":[3,56],"a":[4,13,23,72,83],"widely":[5],"used":[6],"tool":[7],"in":[8,22,27,34,156,162],"cell":[9,36],"culture":[10,31],"applications.":[11],"In":[12,66,143],"typical":[14],"configuration,":[15],"the":[16,30,42,54,59,63,94,98,125,128,132,136,141,147,150,167,174,183,186,191,194],"luminescent":[17],"indicators":[19,45,60,78,177],"are":[20,79],"embedded":[21],"solid,":[24],"oxygen-permeable":[25],"matrix":[26,85],"contact":[28],"with":[29],"medium.":[32],"However,":[33],"sensitive":[35],"cultures":[37],"even":[38],"minimal":[39],"leaching":[40,55,134,181],"of":[41,87,127,140,149,166,185],"potentially":[43],"cytotoxic":[44],"can":[46],"become":[47],"an":[48],"issue.":[49],"One":[50],"way":[51],"to":[52,57,102],"prevent":[53],"immobilize":[58],"covalently":[61,80,151,175],"into":[62,82],"supporting":[64],"matrix.":[65],"this":[67],"paper,":[68],"we":[69,123,145],"report":[70],"on":[71,131,193],"method":[73],"where":[74],"platinum(II)-5,10,15,20-tetrakis-(2,3,4,5,6-pentafluorphenyl)-porphyrin":[75],"(PtTFPP)":[76],"immobilized":[81,176],"polymer":[84],"consisting":[86],"polystyrene":[88],"and":[89,110,118,135,182],"poly(pentafluorostyrene).":[90],"We":[91],"study":[92,124],"how":[93],"covalent":[95,129],"immobilization":[96,130],"influences":[97],"material's":[100],"cytotoxicity":[101,184],"human":[103],"induced":[104],"pluripotent":[105],"stem":[106],"cell-derived":[107],"(hiPSC-derived)":[108],"neurons":[109],"cardiomyocytes":[111],"(CMs)":[112],"through":[113],"7-13":[114],"days":[115],"culturing":[116],"experiments":[117],"various":[119],"viability":[120],"analyses.":[121],"Furthermore,":[122],"effect":[126],"indicator":[133,180],"properties":[139,197],"material.":[142],"addition,":[144],"demonstrate":[146],"use":[148],"linked":[152],"material":[155],"real":[157],"time":[158],"tension":[160],"monitoring":[161],"functional":[163],"hypoxia":[164],"studies":[165],"hiPSC-derived":[168],"CMs.":[169],"The":[170],"results":[171],"show":[172],"that":[173],"substantially":[178],"reduce":[179],"material,":[189],"while":[190],"influence":[192],"remains":[198],"small":[199],"or":[200],"nonexistent.":[201]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":3},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":1}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2020-06-05T00:00:00"}