{"id":"https://openalex.org/W3031285877","doi":"https://doi.org/10.1111/apa.15381","title":"Gastrointestinal involvement in childhood vasculitides","display_name":"Gastrointestinal involvement in childhood vasculitides","publication_year":2020,"publication_date":"2020-06-01","ids":{"openalex":"https://openalex.org/W3031285877","doi":"https://doi.org/10.1111/apa.15381","mag":"3031285877","pmid":"https://pubmed.ncbi.nlm.nih.gov/32479665"},"language":"en","primary_location":{"id":"doi:10.1111/apa.15381","doi":"https://doi.org/10.1111/apa.15381","is_oa":false,"landing_page_url":"https://doi.org/10.1111/apa.15381","pdf_url":null,"source":{"id":"https://openalex.org/S178469169","display_name":"Acta Paediatrica","issn_l":"0365-1436","issn":["0365-1436","0803-5253","1651-2227"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-2","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Acta Paediatrica","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5034698672","display_name":"Sandra Trapani","orcid":"https://orcid.org/0000-0003-1105-1500","observed_orcids":["https://orcid.org/0000-0003-1105-1500"]},"institutions":[{"id":"https://openalex.org/I4210113625","display_name":"Meyer Children's Hospital","ror":"https://ror.org/01n2xwm51","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210113625"]},{"id":"https://openalex.org/I45084792","display_name":"University of Florence","ror":"https://ror.org/04jr1s763","country_code":"IT","type":"education","lineage":["https://openalex.org/I45084792"]}],"countries":["IT"],"is_corresponding":true,"raw_author_name":"Sandra Trapani","raw_affiliation_strings":["Department of Health Sciences, University of Florence and Meyer Children's University Hospital, Florence, Italy"],"raw_orcid":"https://orcid.org/0000-0003-1105-1500","affiliations":[{"raw_affiliation_string":"Department of Health Sciences, University of Florence and Meyer Children's University Hospital, Florence, Italy","institution_ids":["https://openalex.org/I4210113625","https://openalex.org/I45084792"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030930997","display_name":"Chiara Rubino","orcid":"https://orcid.org/0000-0001-7480-3613","observed_orcids":["https://orcid.org/0000-0001-7480-3613"]},"institutions":[{"id":"https://openalex.org/I45084792","display_name":"University of Florence","ror":"https://ror.org/04jr1s763","country_code":"IT","type":"education","lineage":["https://openalex.org/I45084792"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Chiara Rubino","raw_affiliation_strings":["Post-graduate School of Pediatrics, University of Florence, Florence, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Post-graduate School of Pediatrics, University of Florence, Florence, Italy","institution_ids":["https://openalex.org/I45084792"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5000717918","display_name":"Giuseppe Indolfi","orcid":"https://orcid.org/0000-0003-3830-9823","observed_orcids":["https://orcid.org/0000-0003-3830-9823"]},"institutions":[{"id":"https://openalex.org/I4210113625","display_name":"Meyer Children's Hospital","ror":"https://ror.org/01n2xwm51","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210113625"]},{"id":"https://openalex.org/I45084792","display_name":"University of Florence","ror":"https://ror.org/04jr1s763","country_code":"IT","type":"education","lineage":["https://openalex.org/I45084792"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Giuseppe Indolfi","raw_affiliation_strings":["Meyer Children's University Hospital and Department, NEUROFARBA, University of Florence, Florence, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Meyer Children's University Hospital and Department, NEUROFARBA, University of Florence, Florence, Italy","institution_ids":["https://openalex.org/I4210113625","https://openalex.org/I45084792"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5034698672"],"corresponding_institution_ids":["https://openalex.org/I4210113625","https://openalex.org/I45084792"],"apc_list":{"value":3000,"currency":"USD","value_usd":3000},"apc_paid":null,"fwci":0.0723,"has_fulltext":false,"cited_by_count":8,"citation_normalized_percentile":{"value":0.09090909,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"109","issue":"11","first_page":"2226","last_page":"2236"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10697","display_name":"Vasculitis and related conditions","score":0.9965999722480774,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10697","display_name":"Vasculitis and related conditions","score":0.9965999722480774,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11892","display_name":"Kawasaki Disease and Coronary Complications","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11625","display_name":"Abdominal vascular conditions and treatments","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/gastrointestinal-involvement","display_name":"gastrointestinal involvement","score":0.6840000152587891},{"id":"https://openalex.org/keywords/pediatric-vasculitis","display_name":"pediatric vasculitis","score":0.9380000233650208},{"id":"https://openalex.org/keywords/intestinal-ischemia","display_name":"intestinal ischemia","score":0.8289999961853027},{"id":"https://openalex.org/keywords/intestinal-perforation","display_name":"intestinal perforation","score":0.9580000042915344},{"id":"https://openalex.org/keywords/gastrointestinal-bleeding","display_name":"gastrointestinal bleeding","score":0.8059999942779541},{"id":"https://openalex.org/keywords/corticosteroids","display_name":"corticosteroids","score":0.6700000166893005},{"id":"https://openalex.org/keywords/immunosuppressive-drugs","display_name":"immunosuppressants","score":0.9440000057220459},{"id":"https://openalex.org/keywords/vasculitis-diagnosis","display_name":"vasculitis diagnosis","score":0.7480000257492065},{"id":"https://openalex.org/keywords/abdominal-imaging","display_name":"abdominal imaging","score":0.3880000114440918}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9304742813110352},{"id":"https://openalex.org/C2776015282","wikidata":"https://www.wikidata.org/wiki/Q644318","display_name":"Vasculitis","level":3,"score":0.7701435089111328},{"id":"https://openalex.org/C2780852908","wikidata":"https://www.wikidata.org/wiki/Q127076","display_name":"Vomiting","level":2,"score":0.6557042598724365},{"id":"https://openalex.org/C2780955771","wikidata":"https://www.wikidata.org/wiki/Q183425","display_name":"Abdominal pain","level":2,"score":0.6354095935821533},{"id":"https://openalex.org/C2778456384","wikidata":"https://www.wikidata.org/wiki/Q1508510","display_name":"Perforation","level":3,"score":0.5977635979652405},{"id":"https://openalex.org/C2780580376","wikidata":"https://www.wikidata.org/wiki/Q186889","display_name":"Nausea","level":2,"score":0.5516725778579712},{"id":"https://openalex.org/C2776527422","wikidata":"https://www.wikidata.org/wiki/Q745162","display_name":"Polyarteritis nodosa","level":4,"score":0.5280581116676331},{"id":"https://openalex.org/C16005928","wikidata":"https://www.wikidata.org/wiki/Q171171","display_name":"Dermatology","level":1,"score":0.4325453042984009},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.38251304626464844},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.37037771940231323},{"id":"https://openalex.org/C187212893","wikidata":"https://www.wikidata.org/wiki/Q123028","display_name":"Pediatrics","level":1,"score":0.35903334617614746},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.3228578269481659},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.32001081109046936},{"id":"https://openalex.org/C191897082","wikidata":"https://www.wikidata.org/wiki/Q11467","display_name":"Metallurgy","level":1,"score":0.0},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.0},{"id":"https://openalex.org/C2778527123","wikidata":"https://www.wikidata.org/wiki/Q11750728","display_name":"Punching","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000305","descriptor_name":"Adrenal Cortex Hormones","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002648","descriptor_name":"Child","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005767","descriptor_name":"Gastrointestinal Diseases","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D005767","descriptor_name":"Gastrointestinal Diseases","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true},{"descriptor_ui":"D005767","descriptor_name":"Gastrointestinal Diseases","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007166","descriptor_name":"Immunosuppressive Agents","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014657","descriptor_name":"Vasculitis","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D014657","descriptor_name":"Vasculitis","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1111/apa.15381","doi":"https://doi.org/10.1111/apa.15381","is_oa":false,"landing_page_url":"https://doi.org/10.1111/apa.15381","pdf_url":null,"source":{"id":"https://openalex.org/S178469169","display_name":"Acta Paediatrica","issn_l":"0365-1436","issn":["0365-1436","0803-5253","1651-2227"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-2","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Acta Paediatrica","raw_type":"journal-article"},{"id":"pmid:32479665","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/32479665","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Acta paediatrica (Oslo, Norway : 1992)","raw_type":"Journal Article"},{"id":"pmh:oai:flore.unifi.it:2158/1197226","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/2158/1197226","pdf_url":null,"source":{"id":"https://openalex.org/S4306402033","display_name":"Florence Research (University of Florence)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I45084792","host_organization_name":"University of Florence","host_organization_lineage":["https://openalex.org/I45084792"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":1.0,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":62,"referenced_works":["https://openalex.org/W1482196516","https://openalex.org/W1509482628","https://openalex.org/W1554685018","https://openalex.org/W1591870238","https://openalex.org/W1705637284","https://openalex.org/W1756186076","https://openalex.org/W1980452914","https://openalex.org/W1987227201","https://openalex.org/W1992930774","https://openalex.org/W2001431309","https://openalex.org/W2017295978","https://openalex.org/W2023874201","https://openalex.org/W2024213873","https://openalex.org/W2031517139","https://openalex.org/W2037082225","https://openalex.org/W2038103357","https://openalex.org/W2059249378","https://openalex.org/W2066073251","https://openalex.org/W2073861987","https://openalex.org/W2086684499","https://openalex.org/W2090372243","https://openalex.org/W2093778100","https://openalex.org/W2097464423","https://openalex.org/W2101554991","https://openalex.org/W2102260696","https://openalex.org/W2102647537","https://openalex.org/W2108698597","https://openalex.org/W2115243777","https://openalex.org/W2121999121","https://openalex.org/W2145286652","https://openalex.org/W2153611506","https://openalex.org/W2174772393","https://openalex.org/W2284005203","https://openalex.org/W2325125286","https://openalex.org/W2333376796","https://openalex.org/W2342626382","https://openalex.org/W2463012738","https://openalex.org/W2474029657","https://openalex.org/W2508023113","https://openalex.org/W2528511825","https://openalex.org/W2549986306","https://openalex.org/W2563291478","https://openalex.org/W2614667497","https://openalex.org/W2741788318","https://openalex.org/W2762117864","https://openalex.org/W2789669701","https://openalex.org/W2811286423","https://openalex.org/W2884638729","https://openalex.org/W2892014593","https://openalex.org/W2900021602","https://openalex.org/W2901013537","https://openalex.org/W2901918269","https://openalex.org/W2904419734","https://openalex.org/W2908235382","https://openalex.org/W2949076332","https://openalex.org/W2971969692","https://openalex.org/W2981926796","https://openalex.org/W2987173114","https://openalex.org/W2995206298","https://openalex.org/W3024521558","https://openalex.org/W4211141365","https://openalex.org/W4246290455"],"related_works":["https://openalex.org/W2090257389","https://openalex.org/W3177812322","https://openalex.org/W4393315937","https://openalex.org/W4403583700","https://openalex.org/W3214855548","https://openalex.org/W2594008661","https://openalex.org/W2321916853","https://openalex.org/W4230293447","https://openalex.org/W71934920","https://openalex.org/W4389786587"],"abstract_inverted_index":{"AIM:":[0],"The":[1],"aim":[2],"of":[3,13,16,62,123,145,157,164],"this":[4],"narrative":[5],"review":[6],"was":[7],"to":[8,31,120,151],"provide":[9],"a":[10,142],"comprehensive":[11],"summary":[12],"the":[14,21,54,76,80,98,121,162,177],"characteristics":[15],"gastrointestinal":[17],"(GI)":[18],"involvement":[19,64,92,137],"in":[20,41,65,138,176],"most":[22,178],"common":[23,179],"paediatric":[24,139,180],"primary":[25,181],"vasculitides.":[26],"METHODS:":[27],"We":[28],"used":[29],"PubMed":[30],"primarily":[32],"identify":[33],"papers,":[34],"reviews,":[35],"case":[36],"series":[37],"and":[38,60,75,96,114,147,154,166,171,191,197],"editorials":[39],"published":[40],"English":[42],"from":[43],"2000":[44],"until":[45],"31":[46],"January":[47],"2020.":[48],"Based":[49],"on":[50,130,161,189],"this,":[51],"we":[52],"report":[53],"prevalence,":[55],"clinical":[56],"manifestations,":[57],"diagnostic":[58],"approaches":[59],"management":[61],"GI":[63,81,85,91,136,158,174],"each":[66],"vasculitis.":[67,126],"RESULTS:":[68],"Vasculitides":[69],"are":[70,103],"inflammatory":[71],"blood":[72],"vessel":[73],"diseases,":[74],"majority":[77],"can":[78,93],"affect":[79],"system":[82],"with":[83],"vascular,":[84],"tract":[86],"or":[87],"solid":[88],"organ":[89],"involvement.":[90],"sometimes":[94],"complicate":[95],"delay":[97],"correct":[99],"diagnosis.":[100],"Clinical":[101],"findings":[102],"usually":[104,167,184,193],"nonspecific":[105],"symptoms,":[106],"such":[107],"as":[108],"fever,":[109],"abdominal":[110],"pain,":[111],"nausea,":[112],"vomiting":[113],"diarrhoea.":[115],"Bleeding":[116],"should":[117],"alert":[118],"paediatricians":[119],"possibility":[122],"severe":[124],"complicated":[125],"Diagnosis":[127],"relies":[128],"mostly":[129,187],"imaging.":[131],"If":[132],"it":[133],"goes":[134],"unrecognised,":[135],"vasculitis":[140,165],"is":[141],"serious":[143],"cause":[144],"morbidity":[146],"even":[148],"mortality,":[149],"related":[150],"bowel":[152],"ischaemia":[153],"perforation.":[155],"Treatment":[156],"symptoms":[159],"depends":[160],"type":[163],"involves":[168],"high-dose":[169,195],"steroids":[170],"immunosuppressants.":[172,198],"CONCLUSION:":[173],"manifestations":[175],"vasculitides":[182],"were":[183],"nonspecific,":[185],"diagnosis":[186],"relied":[188],"imaging,":[190],"treatment":[192],"involved":[194],"corticosteroids":[196]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":3},{"year":2022,"cited_by_count":1},{"year":2020,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2020-06-05T00:00:00"}