{"id":"https://openalex.org/W3029876533","doi":"https://doi.org/10.3877/cma.j.issn.1674-6902.2017.01.003","title":"Study on pulmonary ventilation function and it\u2032s compensation in different high altitude","display_name":"Study on pulmonary ventilation function and it\u2032s compensation in different high altitude","publication_year":2017,"publication_date":"2017-02-25","ids":{"openalex":"https://openalex.org/W3029876533","doi":"https://doi.org/10.3877/cma.j.issn.1674-6902.2017.01.003","mag":"3029876533"},"language":"en","primary_location":{"id":"mag:3029876533","doi":"https://doi.org/10.3877/cma.j.issn.1674-6902.2017.01.003","is_oa":false,"landing_page_url":"http://rs.yiigle.com/CN119295201701/1068309.htm","pdf_url":null,"source":{"id":"https://openalex.org/S4306506116","display_name":"Chin J Lung Dis(Electronic Edition)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Chin J Lung Dis(Electronic Edition)","raw_type":null},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5102022832","display_name":"Ming Hu","orcid":"https://orcid.org/0000-0002-6062-8794","observed_orcids":["https://orcid.org/0000-0002-6062-8794"]},"institutions":[{"id":"https://openalex.org/I151075929","display_name":"Army Medical University","ror":"https://ror.org/05w21nn13","country_code":"CN","type":"education","lineage":["https://openalex.org/I151075929"]},{"id":"https://openalex.org/I4210117763","display_name":"Xinqiao Hospital","ror":"https://ror.org/02d217z27","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210117763"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ming Hu","raw_affiliation_strings":["Army Institute of Respiratory Diseases, Department of Respiratory Medicine, Xinqiao Hospital, Third Military Medical University, Chongqing 400037, China"],"raw_orcid":"https://orcid.org/0000-0002-6062-8794","affiliations":[{"raw_affiliation_string":"Army Institute of Respiratory Diseases, Department of Respiratory Medicine, Xinqiao Hospital, Third Military Medical University, Chongqing 400037, China","institution_ids":["https://openalex.org/I151075929","https://openalex.org/I4210117763"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100350223","display_name":"Qi Li","orcid":"https://orcid.org/0000-0002-6064-9819","observed_orcids":["https://orcid.org/0000-0002-6064-9819"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Qi Li","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-6064-9819","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020016656","display_name":"Binfeng He","orcid":"https://orcid.org/0000-0002-7243-1972","observed_orcids":["https://orcid.org/0000-0002-7243-1972"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Binfeng He","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-7243-1972","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100709844","display_name":"Dan Wang","orcid":"https://orcid.org/0000-0001-9079-2360","observed_orcids":["https://orcid.org/0000-0001-9079-2360"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Dan Wang","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-9079-2360","affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"Gang Liu","orcid":"https://orcid.org/0000-0002-3636-7029","observed_orcids":["https://orcid.org/0000-0002-3636-7029"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Gang Liu","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-3636-7029","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067660330","display_name":"Jing Xu","orcid":"https://orcid.org/0000-0001-9946-4769","observed_orcids":["https://orcid.org/0000-0001-9946-4769"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jing Xu","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-9946-4769","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020606839","display_name":"Shuanglin Liu","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Shuanglin Liu","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030618874","display_name":"Guansong Wang","orcid":"https://orcid.org/0000-0002-5184-0777","observed_orcids":["https://orcid.org/0000-0002-5184-0777"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Guansong Wang","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-5184-0777","affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5077121753","display_name":"Lan Huang","orcid":"https://orcid.org/0009-0003-9781-1714","observed_orcids":["https://orcid.org/0009-0003-9781-1714"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Lan Huang","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0009-0003-9781-1714","affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.37347554,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"10","issue":"1","first_page":"10","last_page":"14"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11968","display_name":"High Altitude and Hypoxia","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11968","display_name":"High Altitude and Hypoxia","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10728","display_name":"Pulmonary Hypertension Research and Treatments","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11456","display_name":"Neuroscience of respiration and sleep","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2807","display_name":"Endocrine and Autonomic Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/high-altitude","display_name":"high altitude","score":0.7620000243186951},{"id":"https://openalex.org/keywords/pulmonary-ventilation","display_name":"pulmonary ventilation","score":0.7089999914169312},{"id":"https://openalex.org/keywords/acute-hypoxia","display_name":"acute hypoxia","score":0.75},{"id":"https://openalex.org/keywords/endothelin-1","display_name":"endothelin-1","score":0.8799999952316284},{"id":"https://openalex.org/keywords/hypoxia-inducible-factor-1alpha","display_name":"hypoxia-inducible factor-1\u03b1","score":0.9279999732971191},{"id":"https://openalex.org/keywords/angiotensin-converting-enzyme","display_name":"angiotensin-converting enzyme","score":0.9909999966621399},{"id":"https://openalex.org/keywords/forced-vital-capacity","display_name":"forced vital capacity","score":0.7900000214576721},{"id":"https://openalex.org/keywords/6-minute-walk-distance","display_name":"6-minute walk distance","score":0.8889999985694885},{"id":"https://openalex.org/keywords/acclimatization","display_name":"acclimatization","score":0.5929999947547913},{"id":"https://openalex.org/keywords/plasma-biomarkers","display_name":"plasma biomarkers","score":0.5370000004768372},{"id":"https://openalex.org/keywords/respiratory-compensation","display_name":"respiratory compensation","score":0.5490000247955322},{"id":"https://openalex.org/keywords/fev1","display_name":"FEV1","score":0.640999972820282}],"concepts":[{"id":"https://openalex.org/C8240015","wikidata":"https://www.wikidata.org/wiki/Q918226","display_name":"Effects of high altitude on humans","level":2,"score":0.6058985590934753},{"id":"https://openalex.org/C200457457","wikidata":"https://www.wikidata.org/wiki/Q584049","display_name":"Ventilation (architecture)","level":2,"score":0.5953326225280762},{"id":"https://openalex.org/C6350597","wikidata":"https://www.wikidata.org/wiki/Q339495","display_name":"Altitude (triangle)","level":2,"score":0.5865926742553711},{"id":"https://openalex.org/C75603125","wikidata":"https://www.wikidata.org/wiki/Q1877462","display_name":"Pulmonary function testing","level":2,"score":0.5623281002044678},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5573293566703796},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5488662123680115},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.48308447003364563},{"id":"https://openalex.org/C534529494","wikidata":"https://www.wikidata.org/wiki/Q7891","display_name":"Respiratory system","level":2,"score":0.4325188398361206},{"id":"https://openalex.org/C7836513","wikidata":"https://www.wikidata.org/wiki/Q1641506","display_name":"Hypoxia (environmental)","level":3,"score":0.43121856451034546},{"id":"https://openalex.org/C140793950","wikidata":"https://www.wikidata.org/wiki/Q168091","display_name":"Animal science","level":1,"score":0.4218425452709198},{"id":"https://openalex.org/C540031477","wikidata":"https://www.wikidata.org/wiki/Q629","display_name":"Oxygen","level":2,"score":0.1761932373046875},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.13074210286140442},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.12422409653663635},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.1234445869922638},{"id":"https://openalex.org/C153294291","wikidata":"https://www.wikidata.org/wiki/Q25261","display_name":"Meteorology","level":1,"score":0.08528128266334534},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.06693214178085327},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.06287780404090881},{"id":"https://openalex.org/C2524010","wikidata":"https://www.wikidata.org/wiki/Q8087","display_name":"Geometry","level":1,"score":0.0},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"mag:3029876533","doi":"https://doi.org/10.3877/cma.j.issn.1674-6902.2017.01.003","is_oa":false,"landing_page_url":"http://rs.yiigle.com/CN119295201701/1068309.htm","pdf_url":null,"source":{"id":"https://openalex.org/S4306506116","display_name":"Chin J Lung Dis(Electronic Edition)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Chin J Lung Dis(Electronic Edition)","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.98580002784729,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2086462770","https://openalex.org/W1999314501","https://openalex.org/W2155700273","https://openalex.org/W1984521943","https://openalex.org/W2885509094","https://openalex.org/W2461797591","https://openalex.org/W2140152876","https://openalex.org/W2382702186","https://openalex.org/W2039568424","https://openalex.org/W2032049690"],"abstract_inverted_index":{"Objective\r\nTo":[0],"study":[1],"the":[2,84,101,143,222],"change":[3,102,178],"of":[4,8,56,86,100,103,123,147,179,204,224,240,245,247,285],"pulmonary":[5,47,286],"ventilation":[6,48,265,294],"function":[7,49,266],"plainsman":[9],"in":[10,68,125,138,149,156,168,173,206,212,228,233,252,261],"different":[11,69,113],"high":[12,23,167,276],"altitude":[13,24,114],"and":[14,28,50,60,76,83,107,121,129,145,163,181,186,216,221,243,256,267],"potential":[15],"mechanism.\r\n\r\n\r\nMethod\r\nOne":[16],"hundreds":[17],"subjects":[18,57,124,148,205,248,272],"was":[19,115,153,166,194,249],"rapidly":[20,273],"elevated":[21,211],"to":[22,200,281],"3":[25,126,157,187,213,234,257],"700":[26,127,158,188,214,235,258],"m":[27,32,128,132,152,159,171,175,185,189,193,215,219,231,236,255,259],"then":[29],"4":[30,130,150,169,191,217,229,253],"200":[31,131,151,170,192,218,230,254],"from":[33],"sea":[34,139,207,262],"level":[35],"(300":[36],"m).":[37],"They":[38],"had":[39,65,91],"not":[40],"suffered":[41],"with":[42,137],"acute":[43],"mountain":[44],"illness.":[45],"The":[46,71,98,161,177,238],"6":[51,108],"minute":[52,296],"walking":[53,297],"test":[54,298],"(6MWT)":[55],"were":[58,79,133,210,226],"evaluated":[59],"their":[61],"fasting":[62],"blood":[63],"samples":[64],"been":[66,92],"collected":[67],"altitudes.":[70],"plasma":[72,87,201,241],"hypoxia":[73,292],"inducible":[74],"factor-1\u03b1(HIF-1\u03b1)":[75],"endothelin-1(ET-1)":[77],"levels":[78,140,203,223,239,263],"detected":[80],"by":[81,94,117],"ELISA,":[82],"activity":[85,244],"angiotensin":[88],"converting":[89],"enzyme(ACE)":[90],"measured":[93],"continuous":[95],"monitoring":[96],"method.":[97],"correlation":[99,197],"forced":[104],"vital":[105],"capacity(FVC)":[106],"min":[109],"walk":[110],"distance(6MWD)":[111],"among":[112],"analyzed":[116],"Pearson":[118],"analysis.\r\n\r\n\r\nResult\r\nThe":[119],"FVC":[120,144,180],"6MWD":[122,146,182],"significant":[134,250],"decreased,":[135],"compared":[136],"(P<0.05).":[141,160,176,198,237],"And":[142],"lower":[154],"than":[155,172,232,260],"FEV1":[162],"respiratory":[164],"rate":[165],"300":[174,184],"between":[183],"or":[190],"notable":[195],"positive":[196],"Compared":[199],"ET-1":[202,225],"levels,":[208],"they":[209],"(P<0.05)":[220],"higher":[227,251],"HIF-1\u03b1":[242],"ACE":[246],"(P<0.05).\r\n\r\n\r\nConclusions\r\nPulmonary":[264],"it\u2032s":[268],"compensation":[269],"descend":[270],"when":[271],"expose":[274],"at":[275],"altitude,":[277],"which":[278],"might":[279],"due":[280],"a":[282],"small":[283],"amount":[284],"interstitial":[287],"fluid":[288],"retention.\r\n\r\n\r\nKey":[289],"words:":[290],"\r\nAcute":[291],"exposure;\u00a0Pulmonary":[293],"function;\u00a06":[295]},"counts_by_year":[],"updated_date":"2026-10-29T09:56:32.521200","created_date":"2020-06-05T00:00:00"}