{"id":"https://openalex.org/W3029200316","doi":"https://doi.org/10.1208/s12249-020-01677-1","title":"Formulation and Characterization of a 3D-Printed Cryptotanshinone-Loaded Niosomal Hydrogel for Topical Therapy of Acne","display_name":"Formulation and Characterization of a 3D-Printed Cryptotanshinone-Loaded Niosomal Hydrogel for Topical Therapy of Acne","publication_year":2020,"publication_date":"2020-05-31","ids":{"openalex":"https://openalex.org/W3029200316","doi":"https://doi.org/10.1208/s12249-020-01677-1","mag":"3029200316","pmid":"https://pubmed.ncbi.nlm.nih.gov/32476076"},"language":"en","primary_location":{"id":"doi:10.1208/s12249-020-01677-1","doi":"https://doi.org/10.1208/s12249-020-01677-1","is_oa":false,"landing_page_url":"https://doi.org/10.1208/s12249-020-01677-1","pdf_url":null,"source":{"id":"https://openalex.org/S1234972","display_name":"AAPS PharmSciTech","issn_l":"1530-9932","issn":["1530-9932"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","jufo-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"AAPS PharmSciTech","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5082992581","display_name":"Zhuxian Wang","orcid":"https://orcid.org/0000-0002-2083-7209","observed_orcids":["https://orcid.org/0000-0002-2083-7209"]},"institutions":[{"id":"https://openalex.org/I58200834","display_name":"Southern Medical University","ror":"https://ror.org/01vjw4z39","country_code":"CN","type":"education","lineage":["https://openalex.org/I58200834"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zhuxian Wang","raw_affiliation_strings":["School of Traditional Chinese Medicine, Southern Medical University, Guangzhou, 510515, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Traditional Chinese Medicine, Southern Medical University, Guangzhou, 510515, China","institution_ids":["https://openalex.org/I58200834"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100418828","display_name":"Li Liu","orcid":"https://orcid.org/0000-0002-5265-4159","observed_orcids":["https://orcid.org/0000-0002-5265-4159"]},"institutions":[{"id":"https://openalex.org/I58200834","display_name":"Southern Medical University","ror":"https://ror.org/01vjw4z39","country_code":"CN","type":"education","lineage":["https://openalex.org/I58200834"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Li Liu","raw_affiliation_strings":["School of Traditional Chinese Medicine, Southern Medical University, Guangzhou, 510515, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Traditional Chinese Medicine, Southern Medical University, Guangzhou, 510515, China","institution_ids":["https://openalex.org/I58200834"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089928270","display_name":"Shijian Xiang","orcid":"https://orcid.org/0000-0002-7119-5728","observed_orcids":["https://orcid.org/0000-0002-7119-5728"]},"institutions":[{"id":"https://openalex.org/I58200834","display_name":"Southern Medical University","ror":"https://ror.org/01vjw4z39","country_code":"CN","type":"education","lineage":["https://openalex.org/I58200834"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Shijian Xiang","raw_affiliation_strings":["School of Traditional Chinese Medicine, Southern Medical University, Guangzhou, 510515, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Traditional Chinese Medicine, Southern Medical University, Guangzhou, 510515, China","institution_ids":["https://openalex.org/I58200834"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101729627","display_name":"Cuiping Jiang","orcid":"https://orcid.org/0000-0001-9694-5399","observed_orcids":["https://orcid.org/0000-0001-9694-5399"]},"institutions":[{"id":"https://openalex.org/I58200834","display_name":"Southern Medical University","ror":"https://ror.org/01vjw4z39","country_code":"CN","type":"education","lineage":["https://openalex.org/I58200834"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Cuiping Jiang","raw_affiliation_strings":["School of Traditional Chinese Medicine, Southern Medical University, Guangzhou, 510515, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Traditional Chinese Medicine, Southern Medical University, Guangzhou, 510515, China","institution_ids":["https://openalex.org/I58200834"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102525801","display_name":"Wenfeng Wu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I58200834","display_name":"Southern Medical University","ror":"https://ror.org/01vjw4z39","country_code":"CN","type":"education","lineage":["https://openalex.org/I58200834"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Wenfeng Wu","raw_affiliation_strings":["School of Traditional Chinese Medicine, Southern Medical University, Guangzhou, 510515, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Traditional Chinese Medicine, Southern Medical University, Guangzhou, 510515, China","institution_ids":["https://openalex.org/I58200834"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083497882","display_name":"Shi-Fa Ruan","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I58200834","display_name":"Southern Medical University","ror":"https://ror.org/01vjw4z39","country_code":"CN","type":"education","lineage":["https://openalex.org/I58200834"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Shifa Ruan","raw_affiliation_strings":["School of Traditional Chinese Medicine, Southern Medical University, Guangzhou, 510515, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Traditional Chinese Medicine, Southern Medical University, Guangzhou, 510515, China","institution_ids":["https://openalex.org/I58200834"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112738080","display_name":"Qunqun Du","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I58200834","display_name":"Southern Medical University","ror":"https://ror.org/01vjw4z39","country_code":"CN","type":"education","lineage":["https://openalex.org/I58200834"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Qunqun Du","raw_affiliation_strings":["School of Traditional Chinese Medicine, Southern Medical University, Guangzhou, 510515, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Traditional Chinese Medicine, Southern Medical University, Guangzhou, 510515, China","institution_ids":["https://openalex.org/I58200834"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100344108","display_name":"Tingting Chen","orcid":"https://orcid.org/0000-0002-5022-4243","observed_orcids":["https://orcid.org/0000-0002-5022-4243","https://orcid.org/0009-0003-7501-5063"]},"institutions":[{"id":"https://openalex.org/I58200834","display_name":"Southern Medical University","ror":"https://ror.org/01vjw4z39","country_code":"CN","type":"education","lineage":["https://openalex.org/I58200834"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Tingting Chen","raw_affiliation_strings":["School of Traditional Chinese Medicine, Southern Medical University, Guangzhou, 510515, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Traditional Chinese Medicine, Southern Medical University, Guangzhou, 510515, China","institution_ids":["https://openalex.org/I58200834"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110791629","display_name":"Yaqi Xue","orcid":"https://orcid.org/0000-0002-8266-1317","observed_orcids":["https://orcid.org/0000-0002-8266-1317"]},"institutions":[{"id":"https://openalex.org/I58200834","display_name":"Southern Medical University","ror":"https://ror.org/01vjw4z39","country_code":"CN","type":"education","lineage":["https://openalex.org/I58200834"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yaqi Xue","raw_affiliation_strings":["School of Traditional Chinese Medicine, Southern Medical University, Guangzhou, 510515, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Traditional Chinese Medicine, Southern Medical University, Guangzhou, 510515, China","institution_ids":["https://openalex.org/I58200834"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065534779","display_name":"Huoji Chen","orcid":"https://orcid.org/0000-0002-1649-3781","observed_orcids":["https://orcid.org/0000-0002-1649-3781"]},"institutions":[{"id":"https://openalex.org/I58200834","display_name":"Southern Medical University","ror":"https://ror.org/01vjw4z39","country_code":"CN","type":"education","lineage":["https://openalex.org/I58200834"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Huoji Chen","raw_affiliation_strings":["School of Traditional Chinese Medicine, Southern Medical University, Guangzhou, 510515, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Traditional Chinese Medicine, Southern Medical University, Guangzhou, 510515, China","institution_ids":["https://openalex.org/I58200834"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5021818298","display_name":"Lidong Weng","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I58200834","display_name":"Southern Medical University","ror":"https://ror.org/01vjw4z39","country_code":"CN","type":"education","lineage":["https://openalex.org/I58200834"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Lidong Weng","raw_affiliation_strings":["School of Traditional Chinese Medicine, Southern Medical University, Guangzhou, 510515, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Traditional Chinese Medicine, Southern Medical University, Guangzhou, 510515, China","institution_ids":["https://openalex.org/I58200834"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042698255","display_name":"Hongxia Zhu","orcid":"https://orcid.org/0000-0002-6961-5957","observed_orcids":["https://orcid.org/0000-0002-6961-5957"]},"institutions":[{"id":"https://openalex.org/I58200834","display_name":"Southern Medical University","ror":"https://ror.org/01vjw4z39","country_code":"CN","type":"education","lineage":["https://openalex.org/I58200834"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Hongxia Zhu","raw_affiliation_strings":["Integrated Hospital of Traditional Chinese Medicine, Southern Medical University, Guangzhou, 510315, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Integrated Hospital of Traditional Chinese Medicine, Southern Medical University, Guangzhou, 510315, China","institution_ids":["https://openalex.org/I58200834"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044947288","display_name":"Qun Shen","orcid":"https://orcid.org/0000-0002-2154-6104","observed_orcids":["https://orcid.org/0000-0002-2154-6104"]},"institutions":[{"id":"https://openalex.org/I58200834","display_name":"Southern Medical University","ror":"https://ror.org/01vjw4z39","country_code":"CN","type":"education","lineage":["https://openalex.org/I58200834"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Qun Shen","raw_affiliation_strings":["School of Traditional Chinese Medicine, Southern Medical University, Guangzhou, 510515, China. 2451221@qq.com","School of Traditional Chinese Medicine, Southern Medical University, Guangzhou, 510515, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Traditional Chinese Medicine, Southern Medical University, Guangzhou, 510515, China. 2451221@qq.com","institution_ids":["https://openalex.org/I58200834"]},{"raw_affiliation_string":"School of Traditional Chinese Medicine, Southern Medical University, Guangzhou, 510515, China","institution_ids":["https://openalex.org/I58200834"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5005713769","display_name":"Qiang Liu","orcid":"https://orcid.org/0000-0002-9688-188X","observed_orcids":["https://orcid.org/0000-0002-9688-188X"]},"institutions":[{"id":"https://openalex.org/I58200834","display_name":"Southern Medical University","ror":"https://ror.org/01vjw4z39","country_code":"CN","type":"education","lineage":["https://openalex.org/I58200834"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Qiang Liu","raw_affiliation_strings":["School of Traditional Chinese Medicine, Southern Medical University, Guangzhou, 510515, China. liuqiang@smu.edu.cn","School of Traditional Chinese Medicine, Southern Medical University, Guangzhou, 510515, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Traditional Chinese Medicine, Southern Medical University, Guangzhou, 510515, China. liuqiang@smu.edu.cn","institution_ids":["https://openalex.org/I58200834"]},{"raw_affiliation_string":"School of Traditional Chinese Medicine, Southern Medical University, Guangzhou, 510515, China","institution_ids":["https://openalex.org/I58200834"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5005713769","https://openalex.org/A5044947288"],"corresponding_institution_ids":["https://openalex.org/I58200834"],"apc_list":{"value":3260,"currency":"USD","value_usd":3260},"apc_paid":null,"fwci":2.738,"has_fulltext":false,"cited_by_count":51,"citation_normalized_percentile":{"value":0.89975816,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":98,"max":99},"biblio":{"volume":"21","issue":"5","first_page":"159","last_page":"159"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10704","display_name":"Advancements in Transdermal Drug Delivery","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/3003","display_name":"Pharmaceutical Science"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10704","display_name":"Advancements in Transdermal Drug Delivery","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/3003","display_name":"Pharmaceutical Science"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10920","display_name":"Advanced Drug Delivery Systems","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/3003","display_name":"Pharmaceutical Science"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11553","display_name":"Acne and Rosacea Treatments and Effects","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2708","display_name":"Dermatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cryptotanshinone","display_name":"cryptotanshinone","score":0.9990000128746033},{"id":"https://openalex.org/keywords/niosomes","display_name":"niosomes","score":0.8230000138282776},{"id":"https://openalex.org/keywords/3d-printing","display_name":"3D printing","score":0.9570000171661377},{"id":"https://openalex.org/keywords/acne-treatment","display_name":"acne treatment","score":0.5910000205039978},{"id":"https://openalex.org/keywords/topical-drug-delivery","display_name":"topical drug delivery","score":0.9869999885559082},{"id":"https://openalex.org/keywords/material-extrusion","display_name":"material extrusion","score":0.871999979019165},{"id":"https://openalex.org/keywords/transdermal-drug-delivery","display_name":"transdermal drug delivery","score":0.8149999976158142},{"id":"https://openalex.org/keywords/skin-permeation","display_name":"skin permeation","score":0.5799999833106995},{"id":"https://openalex.org/keywords/stratum-corneum","display_name":"stratum corneum","score":0.7350000143051147},{"id":"https://openalex.org/keywords/skin-hydration","display_name":"skin hydration","score":0.6050000190734863},{"id":"https://openalex.org/keywords/personalized-medicine","display_name":"personalized medicine","score":0.5979999899864197},{"id":"https://openalex.org/keywords/anti-acne-activity","display_name":"anti-acne activity","score":0.7649999856948853}],"concepts":[{"id":"https://openalex.org/C72918618","wikidata":"https://www.wikidata.org/wiki/Q1993211","display_name":"Niosome","level":4,"score":0.9673254489898682},{"id":"https://openalex.org/C2777673923","wikidata":"https://www.wikidata.org/wiki/Q79928","display_name":"Acne","level":2,"score":0.7760965824127197},{"id":"https://openalex.org/C2778370115","wikidata":"https://www.wikidata.org/wiki/Q2038676","display_name":"Stratum corneum","level":2,"score":0.6517605781555176},{"id":"https://openalex.org/C205679159","wikidata":"https://www.wikidata.org/wiki/Q3375179","display_name":"Transdermal","level":2,"score":0.572515070438385},{"id":"https://openalex.org/C50670333","wikidata":"https://www.wikidata.org/wiki/Q907651","display_name":"Permeation","level":3,"score":0.5193451642990112},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5085276365280151},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.3903932273387909},{"id":"https://openalex.org/C136229726","wikidata":"https://www.wikidata.org/wiki/Q327092","display_name":"Biomedical engineering","level":1,"score":0.38778769969940186},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.37251079082489014},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.35442543029785156},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.25020599365234375},{"id":"https://openalex.org/C16005928","wikidata":"https://www.wikidata.org/wiki/Q171171","display_name":"Dermatology","level":1,"score":0.19452720880508423},{"id":"https://openalex.org/C41625074","wikidata":"https://www.wikidata.org/wiki/Q176088","display_name":"Membrane","level":2,"score":0.11401700973510742},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.1046912670135498},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.0},{"id":"https://openalex.org/C130316041","wikidata":"https://www.wikidata.org/wiki/Q189206","display_name":"Vesicle","level":3,"score":0.0}],"mesh":[{"descriptor_ui":"D000152","descriptor_name":"Acne Vulgaris","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D000279","descriptor_name":"Administration, Cutaneous","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008081","descriptor_name":"Liposomes","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010316","descriptor_name":"Particle Size","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010616","descriptor_name":"Phenanthrenes","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true},{"descriptor_ui":"D010616","descriptor_name":"Phenanthrenes","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D012867","descriptor_name":"Skin","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012869","descriptor_name":"Skin Absorption","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016503","descriptor_name":"Drug Delivery Systems","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020100","descriptor_name":"Hydrogels","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D066330","descriptor_name":"Printing, Three-Dimensional","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1208/s12249-020-01677-1","doi":"https://doi.org/10.1208/s12249-020-01677-1","is_oa":false,"landing_page_url":"https://doi.org/10.1208/s12249-020-01677-1","pdf_url":null,"source":{"id":"https://openalex.org/S1234972","display_name":"AAPS PharmSciTech","issn_l":"1530-9932","issn":["1530-9932"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","jufo-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"AAPS PharmSciTech","raw_type":"journal-article"},{"id":"pmid:32476076","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/32476076","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"AAPS PharmSciTech","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.8199999928474426,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":56,"referenced_works":["https://openalex.org/W178290327","https://openalex.org/W1928078716","https://openalex.org/W1964826558","https://openalex.org/W1969973561","https://openalex.org/W1970231579","https://openalex.org/W1971324979","https://openalex.org/W1971398930","https://openalex.org/W1972116828","https://openalex.org/W1978675383","https://openalex.org/W1988144726","https://openalex.org/W1988400258","https://openalex.org/W1997764251","https://openalex.org/W2014100777","https://openalex.org/W2015156802","https://openalex.org/W2020458523","https://openalex.org/W2021985090","https://openalex.org/W2027313185","https://openalex.org/W2027743108","https://openalex.org/W2027913641","https://openalex.org/W2033362260","https://openalex.org/W2034692007","https://openalex.org/W2035632119","https://openalex.org/W2055231695","https://openalex.org/W2058009653","https://openalex.org/W2058207390","https://openalex.org/W2063776447","https://openalex.org/W2067243972","https://openalex.org/W2069516100","https://openalex.org/W2069564482","https://openalex.org/W2077806499","https://openalex.org/W2102432127","https://openalex.org/W2133566692","https://openalex.org/W2140416502","https://openalex.org/W2146136320","https://openalex.org/W2399031825","https://openalex.org/W2415205659","https://openalex.org/W2419277797","https://openalex.org/W2424671968","https://openalex.org/W2482765228","https://openalex.org/W2528153599","https://openalex.org/W2563555591","https://openalex.org/W2582640368","https://openalex.org/W2770008468","https://openalex.org/W2782511968","https://openalex.org/W2784057510","https://openalex.org/W2788246550","https://openalex.org/W2806730922","https://openalex.org/W2809699687","https://openalex.org/W2868238225","https://openalex.org/W2895030678","https://openalex.org/W2899779075","https://openalex.org/W2902811605","https://openalex.org/W2923324495","https://openalex.org/W2931638968","https://openalex.org/W2936758417","https://openalex.org/W2948929836"],"related_works":["https://openalex.org/W2482765228","https://openalex.org/W2563555591","https://openalex.org/W4415342852","https://openalex.org/W7154474261","https://openalex.org/W4408225147","https://openalex.org/W4388730938","https://openalex.org/W7124489082","https://openalex.org/W3092918842","https://openalex.org/W7160831175","https://openalex.org/W7213943825"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":7},{"year":2025,"cited_by_count":9},{"year":2024,"cited_by_count":7},{"year":2023,"cited_by_count":9},{"year":2022,"cited_by_count":11},{"year":2021,"cited_by_count":8}],"updated_date":"2026-11-12T12:28:57.059296","created_date":"2020-06-05T00:00:00"}