{"id":"https://openalex.org/W3028719633","doi":"https://doi.org/10.3760/cma.j.issn.0254-5098.2010.06.023","title":"Therapeutic effects and quality of life in 37 glioma patients with postoperative intensity-modulated radiotherapy","display_name":"Therapeutic effects and quality of life in 37 glioma patients with postoperative intensity-modulated radiotherapy","publication_year":2010,"publication_date":"2010-12-25","ids":{"openalex":"https://openalex.org/W3028719633","doi":"https://doi.org/10.3760/cma.j.issn.0254-5098.2010.06.023","mag":"3028719633"},"language":"en","primary_location":{"id":"mag:3028719633","doi":"https://doi.org/10.3760/cma.j.issn.0254-5098.2010.06.023","is_oa":false,"landing_page_url":"http://rs.yiigle.com/CN112271201006/158228.htm","pdf_url":null,"source":{"id":"https://openalex.org/S2764669166","display_name":"Zhonghua fangshe yixue yu fanghu zazhi","issn_l":"0254-5098","issn":["0254-5098"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":["poland-20","russia-white-list-4"],"host_organization":"https://openalex.org/P4320800525","host_organization_name":"Chinese Medical Association","host_organization_lineage":["https://openalex.org/P4320800525"],"host_organization_lineage_names":["Chinese Medical Association"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Zhonghua fangshe yixue yu fanghu zazhi","raw_type":null},"volume":null,"type":"article","indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5110244590","display_name":"Danfang Yan","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210166576","display_name":"First Affiliated Hospital Zhejiang University","ror":"https://ror.org/05m1p5x56","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210166576"]},{"id":"https://openalex.org/I76130692","display_name":"Zhejiang University","ror":"https://ror.org/00a2xv884","country_code":"CN","type":"education","lineage":["https://openalex.org/I76130692"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Danfang Yan","raw_affiliation_strings":["Department of Radiation Oncology The First Affiliated Hospital College of Medicine Zhejiang University Hangzhou 310003 China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology The First Affiliated Hospital College of Medicine Zhejiang University Hangzhou 310003 China","institution_ids":["https://openalex.org/I4210166576","https://openalex.org/I76130692"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5021520299","display_name":"Senxiang Yan","orcid":"https://orcid.org/0000-0001-6902-0892","observed_orcids":["https://orcid.org/0000-0001-6902-0892"]},"institutions":[{"id":"https://openalex.org/I4210166576","display_name":"First Affiliated Hospital Zhejiang University","ror":"https://ror.org/05m1p5x56","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210166576"]},{"id":"https://openalex.org/I76130692","display_name":"Zhejiang University","ror":"https://ror.org/00a2xv884","country_code":"CN","type":"education","lineage":["https://openalex.org/I76130692"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Senxiang Yan","raw_affiliation_strings":["Department of Radiation Oncology The First Affiliated Hospital College of Medicine Zhejiang University Hangzhou 310003 China"],"raw_orcid":"https://orcid.org/0000-0001-6902-0892","affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology The First Affiliated Hospital College of Medicine Zhejiang University Hangzhou 310003 China","institution_ids":["https://openalex.org/I4210166576","https://openalex.org/I76130692"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101847040","display_name":"Jinsong Yang","orcid":"https://orcid.org/0000-0001-6318-2524","observed_orcids":["https://orcid.org/0000-0001-6318-2524","https://orcid.org/0009-0007-4940-9420"]},"institutions":[{"id":"https://openalex.org/I4210166576","display_name":"First Affiliated Hospital Zhejiang University","ror":"https://ror.org/05m1p5x56","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210166576"]},{"id":"https://openalex.org/I76130692","display_name":"Zhejiang University","ror":"https://ror.org/00a2xv884","country_code":"CN","type":"education","lineage":["https://openalex.org/I76130692"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jinsong Yang","raw_affiliation_strings":["Department of Radiation Oncology The First Affiliated Hospital College of Medicine Zhejiang University Hangzhou 310003 China"],"raw_orcid":"https://orcid.org/0000-0001-6318-2524","affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology The First Affiliated Hospital College of Medicine Zhejiang University Hangzhou 310003 China","institution_ids":["https://openalex.org/I4210166576","https://openalex.org/I76130692"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100698629","display_name":"Xiaoli Sun","orcid":"https://orcid.org/0000-0002-7286-0435","observed_orcids":["https://orcid.org/0000-0002-7286-0435"]},"institutions":[{"id":"https://openalex.org/I4210166576","display_name":"First Affiliated Hospital Zhejiang University","ror":"https://ror.org/05m1p5x56","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210166576"]},{"id":"https://openalex.org/I76130692","display_name":"Zhejiang University","ror":"https://ror.org/00a2xv884","country_code":"CN","type":"education","lineage":["https://openalex.org/I76130692"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xiaoli Sun","raw_affiliation_strings":["Department of Radiation Oncology The First Affiliated Hospital College of Medicine Zhejiang University Hangzhou 310003 China"],"raw_orcid":"https://orcid.org/0000-0002-7286-0435","affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology The First Affiliated Hospital College of Medicine Zhejiang University Hangzhou 310003 China","institution_ids":["https://openalex.org/I4210166576","https://openalex.org/I76130692"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100308690","display_name":"Zhongjie Lu","orcid":"https://orcid.org/0000-0002-9648-1931","observed_orcids":["https://orcid.org/0000-0002-9648-1931"]},"institutions":[{"id":"https://openalex.org/I4210166576","display_name":"First Affiliated Hospital Zhejiang University","ror":"https://ror.org/05m1p5x56","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210166576"]},{"id":"https://openalex.org/I76130692","display_name":"Zhejiang University","ror":"https://ror.org/00a2xv884","country_code":"CN","type":"education","lineage":["https://openalex.org/I76130692"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zhongjie Lu","raw_affiliation_strings":["Department of Radiation Oncology The First Affiliated Hospital College of Medicine Zhejiang University Hangzhou 310003 China"],"raw_orcid":"https://orcid.org/0000-0002-9648-1931","affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology The First Affiliated Hospital College of Medicine Zhejiang University Hangzhou 310003 China","institution_ids":["https://openalex.org/I4210166576","https://openalex.org/I76130692"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.3769518,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"30","issue":"06","first_page":"721","last_page":"724"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10129","display_name":"Glioma Diagnosis and Treatment","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2716","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10129","display_name":"Glioma Diagnosis and Treatment","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2716","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10358","display_name":"Advanced Radiotherapy Techniques","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/3108","display_name":"Radiation"},"field":{"id":"https://openalex.org/fields/31","display_name":"Physics and Astronomy"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11176","display_name":"Radiation Therapy and Dosimetry","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/glioma","display_name":"glioma","score":0.9980000257492065},{"id":"https://openalex.org/keywords/intensity-modulated-radiotherapy","display_name":"intensity-modulated radiotherapy","score":0.9909999966621399},{"id":"https://openalex.org/keywords/postoperative-radiotherapy","display_name":"postoperative radiotherapy","score":0.9359999895095825},{"id":"https://openalex.org/keywords/quality-of-life","display_name":"quality of life","score":0.9909999966621399},{"id":"https://openalex.org/keywords/cognitive-function","display_name":"cognitive function","score":0.6710000038146973},{"id":"https://openalex.org/keywords/memory-decline","display_name":"memory decline","score":0.8379999995231628},{"id":"https://openalex.org/keywords/radiation-induced-fatigue","display_name":"radiation-induced fatigue","score":0.6589999794960022},{"id":"https://openalex.org/keywords/survival","display_name":"survival","score":0.42100000381469727},{"id":"https://openalex.org/keywords/progression-free-survival","display_name":"progression-free survival","score":0.9520000219345093},{"id":"https://openalex.org/keywords/gross-tumor-volume","display_name":"gross tumor volume","score":0.675000011920929},{"id":"https://openalex.org/keywords/clinical-target-volume","display_name":"clinical target volume","score":0.8389999866485596},{"id":"https://openalex.org/keywords/planning-target-volume","display_name":"planning target volume","score":0.7409999966621399}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8933107852935791},{"id":"https://openalex.org/C2778227246","wikidata":"https://www.wikidata.org/wiki/Q1365309","display_name":"Glioma","level":2,"score":0.807500958442688},{"id":"https://openalex.org/C509974204","wikidata":"https://www.wikidata.org/wiki/Q180507","display_name":"Radiation therapy","level":2,"score":0.6643110513687134},{"id":"https://openalex.org/C2779951463","wikidata":"https://www.wikidata.org/wiki/Q7268788","display_name":"Quality of life (healthcare)","level":2,"score":0.551659345626831},{"id":"https://openalex.org/C2989005","wikidata":"https://www.wikidata.org/wiki/Q214963","display_name":"Nuclear medicine","level":1,"score":0.5197176933288574},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.3771655857563019},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.3515360355377197},{"id":"https://openalex.org/C159110408","wikidata":"https://www.wikidata.org/wiki/Q121176","display_name":"Nursing","level":1,"score":0.0},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"mag:3028719633","doi":"https://doi.org/10.3760/cma.j.issn.0254-5098.2010.06.023","is_oa":false,"landing_page_url":"http://rs.yiigle.com/CN112271201006/158228.htm","pdf_url":null,"source":{"id":"https://openalex.org/S2764669166","display_name":"Zhonghua fangshe yixue yu fanghu zazhi","issn_l":"0254-5098","issn":["0254-5098"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":["poland-20","russia-white-list-4"],"host_organization":"https://openalex.org/P4320800525","host_organization_name":"Chinese Medical Association","host_organization_lineage":["https://openalex.org/P4320800525"],"host_organization_lineage_names":["Chinese Medical Association"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Zhonghua fangshe yixue yu fanghu zazhi","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":1.0,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2364006258","https://openalex.org/W4291672697","https://openalex.org/W2350435206","https://openalex.org/W2609964055","https://openalex.org/W2360195104","https://openalex.org/W4366274734","https://openalex.org/W2086414958","https://openalex.org/W2350463475","https://openalex.org/W1969129112","https://openalex.org/W2353438428"],"abstract_inverted_index":{"Objective":[0],"To":[1],"evaluate":[2],"treatment":[3,177],"outcomes":[4,178],"and":[5,19,65,69,94,102,110,139,170,179,186,196,215,232],"quality":[6],"of":[7,26,132,142,172,235,243],"life":[8],"(QOL)":[9],"in":[10],"glioma":[11,41,138,238],"patients":[12,35,46,193],"treated":[13],"with":[14,36,60,103,129,154],"postoperative":[15,211],"intensity-modulated":[16],"radiotherapy":[17],"(IMRT),":[18],"to":[20,32,66,70,73,164],"explore":[21],"the":[22,149,165,192],"possible":[23],"clinical":[24,119],"factors":[25],"affecting":[27],"QOL.":[28],"Methods":[29],"From":[30],"2007":[31],"2009,":[33],"37":[34],"low":[37,99,136],"or":[38,219],"high":[39,91,115,146],"grade":[40,100,116,137,147],"were":[42,47,181,194,213,223],"analyzed":[43],"retrospectively.":[44],"All":[45],"operated":[48],"by":[49],"tumor":[50,82,96,112],"resection":[51],"below":[52],"microscopy.":[53],"IMRT":[54,212,228],"began":[55],"at":[56],"2-4":[57],"week":[58],"postoperstion":[59],"2.0":[61],"Gy/fractior,":[62],"5":[63],"fractions/week":[64],"shrink":[67],"portal":[68],"add":[71],"dose":[72],"50-60":[74],"Gy/25-30":[75],"fractions":[76],"after":[77,210],"40-50":[78],"Gy.":[79],"The":[80,118,184,199,207],"gross":[81],"volume":[83,121,152],"(GTV)":[84],"was":[85,125,204],"defined":[86,126],"as":[87,127],"preoperation":[88,104],"T2WI":[89],"MRI":[90,106],"sign":[92],"area":[93,109],"postoperation":[95,111],"cavity":[97,113],"for":[98,114,135,145,160,168,190,237],"glioma,":[101],"T1WI":[105],"enhanced":[107],"abnormity":[108],"glioma.":[117],"target":[120,151],"(":[122,174],"CTV":[123,155],")":[124],"GTV":[128],"a":[130,140],"margin":[131,141,159],"1.5":[133],"cm":[134,144,158],"2.5":[143],"ghoma,":[148],"planning":[150],"(PTV)":[153],"plus":[156],"0.4":[157],"setup":[161],"errors":[162],"according":[163],"European":[166],"Organization":[167],"Research":[169],"Treatment":[171],"Cancer":[173],"EORTC":[175],").The":[176],"QOL":[180],"assessed.":[182],"Results":[183],"half-year":[185],"one-year":[187],"survival":[188,202],"rates":[189],"all":[191],"100%":[195],"79.2%,":[197],"respectively.":[198],"median":[200],"progression-free":[201],"time":[203],"10":[205],"months.":[206],"main":[208],"side-responses":[209],"fatigue":[214],"mild":[216],"memory":[217],"decline":[218],"cognitive":[220],"disabilities,":[221],"which":[222],"radiation":[224],"dose-dependent.":[225],"Conclusions":[226],"Postoperative":[227],"is":[229],"an":[230],"effective":[231],"safe":[233],"modality":[234],"therapy":[236],"patients.\r\n\r\nKey":[239],"words:":[240],"\r\nGlioma;\u00a0Intensity-modulated":[241],"radiotherapy;\u00a0Quality":[242],"life;\u00a0Cognitive":[244],"function;\u00a0Memory":[245],"disorder":[246]},"counts_by_year":[],"updated_date":"2026-10-12T09:40:04.860316","created_date":"2020-06-05T00:00:00"}