{"id":"https://openalex.org/W3028433232","doi":"https://doi.org/10.1308/rcsann.2020.0100","title":"Oncological outcomes in patients undergoing major glossectomy for advanced carcinoma of the oral tongue","display_name":"Oncological outcomes in patients undergoing major glossectomy for advanced carcinoma of the oral tongue","publication_year":2020,"publication_date":"2020-05-21","ids":{"openalex":"https://openalex.org/W3028433232","doi":"https://doi.org/10.1308/rcsann.2020.0100","mag":"3028433232","pmid":"https://pubmed.ncbi.nlm.nih.gov/32436723","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/7450443"},"language":"en","primary_location":{"id":"doi:10.1308/rcsann.2020.0100","doi":"https://doi.org/10.1308/rcsann.2020.0100","is_oa":false,"landing_page_url":"https://doi.org/10.1308/rcsann.2020.0100","pdf_url":null,"source":{"id":"https://openalex.org/S85077419","display_name":"Annals of The Royal College of Surgeons of England","issn_l":"0035-8843","issn":["0035-8843","1478-7083"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","jufo-1","medline","norway-1","poland-40","russia-white-list-2"],"host_organization":"https://openalex.org/P4310311544","host_organization_name":"Royal College of Surgeons of England","host_organization_lineage":["https://openalex.org/P4310311544"],"host_organization_lineage_names":["Royal College of Surgeons of England"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Annals of The Royal College of Surgeons of England","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC7450443/","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5013722135","display_name":"Rakesh Katna","orcid":"https://orcid.org/0000-0003-1677-5348","observed_orcids":["https://orcid.org/0000-0003-1677-5348"]},"institutions":[{"id":"https://openalex.org/I2802099312","display_name":"Jaslok Hospital","ror":"https://ror.org/052w06y65","country_code":"IN","type":"healthcare","lineage":["https://openalex.org/I2802099312"]},{"id":"https://openalex.org/I4210135821","display_name":"Bombay Hospital","ror":"https://ror.org/03xmsh521","country_code":"IN","type":"healthcare","lineage":["https://openalex.org/I4210135821"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"R Katna","raw_affiliation_strings":["Bombay Hospital and Medical Research Centre, Mumbai, India","Jaslok Hospital and Research Centre, Mumbai, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bombay Hospital and Medical Research Centre, Mumbai, India","institution_ids":["https://openalex.org/I4210135821"]},{"raw_affiliation_string":"Jaslok Hospital and Research Centre, Mumbai, India","institution_ids":["https://openalex.org/I2802099312"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110326505","display_name":"B Bhosale","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2802099312","display_name":"Jaslok Hospital","ror":"https://ror.org/052w06y65","country_code":"IN","type":"healthcare","lineage":["https://openalex.org/I2802099312"]},{"id":"https://openalex.org/I4210135821","display_name":"Bombay Hospital","ror":"https://ror.org/03xmsh521","country_code":"IN","type":"healthcare","lineage":["https://openalex.org/I4210135821"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"B Bhosale","raw_affiliation_strings":["Bombay Hospital and Medical Research Centre, Mumbai, India","Jaslok Hospital and Research Centre, Mumbai, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bombay Hospital and Medical Research Centre, Mumbai, India","institution_ids":["https://openalex.org/I4210135821"]},{"raw_affiliation_string":"Jaslok Hospital and Research Centre, Mumbai, India","institution_ids":["https://openalex.org/I2802099312"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101837350","display_name":"Ravi Shankar Sharma","orcid":"https://orcid.org/0000-0002-9047-3279","observed_orcids":["https://orcid.org/0000-0002-9047-3279"]},"institutions":[{"id":"https://openalex.org/I4210135821","display_name":"Bombay Hospital","ror":"https://ror.org/03xmsh521","country_code":"IN","type":"healthcare","lineage":["https://openalex.org/I4210135821"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"R Sharma","raw_affiliation_strings":["Bombay Hospital and Medical Research Centre, Mumbai, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bombay Hospital and Medical Research Centre, Mumbai, India","institution_ids":["https://openalex.org/I4210135821"]}]},{"author_position":"middle","author":{"id":null,"display_name":"S Singh","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210135821","display_name":"Bombay Hospital","ror":"https://ror.org/03xmsh521","country_code":"IN","type":"healthcare","lineage":["https://openalex.org/I4210135821"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"S Singh","raw_affiliation_strings":["Bombay Hospital and Medical Research Centre, Mumbai, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bombay Hospital and Medical Research Centre, Mumbai, India","institution_ids":["https://openalex.org/I4210135821"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103005273","display_name":"Akshay Deshpande","orcid":"https://orcid.org/0009-0009-5944-8356","observed_orcids":["https://orcid.org/0009-0009-5944-8356"]},"institutions":[{"id":"https://openalex.org/I2802099312","display_name":"Jaslok Hospital","ror":"https://ror.org/052w06y65","country_code":"IN","type":"healthcare","lineage":["https://openalex.org/I2802099312"]},{"id":"https://openalex.org/I4210135821","display_name":"Bombay Hospital","ror":"https://ror.org/03xmsh521","country_code":"IN","type":"healthcare","lineage":["https://openalex.org/I4210135821"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"A Deshpande","raw_affiliation_strings":["Bombay Hospital and Medical Research Centre, Mumbai, India","Jaslok Hospital and Research Centre, Mumbai, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bombay Hospital and Medical Research Centre, Mumbai, India","institution_ids":["https://openalex.org/I4210135821"]},{"raw_affiliation_string":"Jaslok Hospital and Research Centre, Mumbai, India","institution_ids":["https://openalex.org/I2802099312"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5018220019","display_name":"Nikhil Dhirendra Kalyani","orcid":"https://orcid.org/0000-0002-9995-3703","observed_orcids":["https://orcid.org/0000-0002-9995-3703"]},"institutions":[{"id":"https://openalex.org/I2802099312","display_name":"Jaslok Hospital","ror":"https://ror.org/052w06y65","country_code":"IN","type":"healthcare","lineage":["https://openalex.org/I2802099312"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"N Kalyani","raw_affiliation_strings":["Jaslok Hospital and Research Centre, Mumbai, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Jaslok Hospital and Research Centre, Mumbai, India","institution_ids":["https://openalex.org/I2802099312"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":7,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"102","issue":"7","first_page":"514","last_page":"518"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10307","display_name":"Head and Neck Cancer Studies","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2733","display_name":"Otorhinolaryngology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10307","display_name":"Head and Neck Cancer Studies","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2733","display_name":"Otorhinolaryngology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11669","display_name":"Head and Neck Surgical Oncology","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11452","display_name":"Oral Health Pathology and Treatment","score":0.0,"subfield":{"id":"https://openalex.org/subfields/3500","display_name":"General Dentistry"},"field":{"id":"https://openalex.org/fields/35","display_name":"Dentistry"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/oral-tongue-cancer","display_name":"oral tongue cancer","score":0.8389999866485596},{"id":"https://openalex.org/keywords/advanced-tongue-cancer","display_name":"advanced tongue cancer","score":0.7799999713897705},{"id":"https://openalex.org/keywords/locoregional-recurrence","display_name":"locoregional recurrence","score":0.902999997138977},{"id":"https://openalex.org/keywords/distant-metastasis","display_name":"distant metastasis","score":0.8600000143051147},{"id":"https://openalex.org/keywords/disease-free-survival","display_name":"disease-free survival","score":0.8569999933242798},{"id":"https://openalex.org/keywords/overall-survival","display_name":"overall survival","score":0.9909999966621399},{"id":"https://openalex.org/keywords/locoregional-control","display_name":"locoregional control","score":0.9279999732971191},{"id":"https://openalex.org/keywords/perineural-invasion","display_name":"perineural invasion","score":0.8790000081062317},{"id":"https://openalex.org/keywords/prognostic-factors","display_name":"prognostic factors","score":0.8809999823570251}],"concepts":[{"id":"https://openalex.org/C2779744641","wikidata":"https://www.wikidata.org/wiki/Q9614","display_name":"Tongue","level":2,"score":0.8204878568649292},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8019551038742065},{"id":"https://openalex.org/C2776426517","wikidata":"https://www.wikidata.org/wiki/Q5571908","display_name":"Glossectomy","level":3,"score":0.7871293425559998},{"id":"https://openalex.org/C2777546739","wikidata":"https://www.wikidata.org/wiki/Q33525","display_name":"Carcinoma","level":2,"score":0.581219494342804},{"id":"https://openalex.org/C2909392909","wikidata":"https://www.wikidata.org/wiki/Q1143025","display_name":"Tongue Neoplasm","level":3,"score":0.5765529274940491},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.4810205101966858},{"id":"https://openalex.org/C61434518","wikidata":"https://www.wikidata.org/wiki/Q932510","display_name":"General surgery","level":1,"score":0.37722092866897583},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.182153582572937}],"mesh":[{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005500","descriptor_name":"Follow-Up Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005927","descriptor_name":"Glossectomy","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007194","descriptor_name":"India","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D008207","descriptor_name":"Lymphatic Metastasis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009364","descriptor_name":"Neoplasm Recurrence, Local","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D009364","descriptor_name":"Neoplasm Recurrence, Local","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":true},{"descriptor_ui":"D009367","descriptor_name":"Neoplasm Staging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014059","descriptor_name":"Tongue","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D014059","descriptor_name":"Tongue","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":false},{"descriptor_ui":"D014062","descriptor_name":"Tongue Neoplasms","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D014062","descriptor_name":"Tongue Neoplasms","qualifier_ui":"Q000556","qualifier_name":"secondary","is_major_topic":false},{"descriptor_ui":"D014062","descriptor_name":"Tongue Neoplasms","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":true},{"descriptor_ui":"D015996","descriptor_name":"Survival Rate","qualifier_ui":"Q000639","qualifier_name":"trends","is_major_topic":false},{"descriptor_ui":"D018572","descriptor_name":"Disease-Free Survival","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055815","descriptor_name":"Young Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1308/rcsann.2020.0100","doi":"https://doi.org/10.1308/rcsann.2020.0100","is_oa":false,"landing_page_url":"https://doi.org/10.1308/rcsann.2020.0100","pdf_url":null,"source":{"id":"https://openalex.org/S85077419","display_name":"Annals of The Royal College of Surgeons of England","issn_l":"0035-8843","issn":["0035-8843","1478-7083"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","jufo-1","medline","norway-1","poland-40","russia-white-list-2"],"host_organization":"https://openalex.org/P4310311544","host_organization_name":"Royal College of Surgeons of England","host_organization_lineage":["https://openalex.org/P4310311544"],"host_organization_lineage_names":["Royal College of Surgeons of England"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Annals of The Royal College of Surgeons of England","raw_type":"journal-article"},{"id":"pmid:32436723","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/32436723","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annals of the Royal College of Surgeons of England","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:7450443","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC7450443/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Ann R Coll Surg Engl","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:7450443","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC7450443/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Ann R Coll Surg Engl","raw_type":"Text"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":1.0,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":20,"referenced_works":["https://openalex.org/W233772007","https://openalex.org/W1481253061","https://openalex.org/W1579637700","https://openalex.org/W1616901229","https://openalex.org/W1968448782","https://openalex.org/W1976066764","https://openalex.org/W1977359308","https://openalex.org/W2008221280","https://openalex.org/W2019707920","https://openalex.org/W2070477357","https://openalex.org/W2106688980","https://openalex.org/W2142222095","https://openalex.org/W2164432851","https://openalex.org/W2597825756","https://openalex.org/W2767834674","https://openalex.org/W2801736448","https://openalex.org/W2913835466","https://openalex.org/W2921731916","https://openalex.org/W3151241602","https://openalex.org/W4254096656"],"related_works":["https://openalex.org/W3160055380","https://openalex.org/W233772007","https://openalex.org/W1972393269","https://openalex.org/W2086771231","https://openalex.org/W2050365349","https://openalex.org/W4416074063","https://openalex.org/W4224246901","https://openalex.org/W2164432851","https://openalex.org/W4396732222","https://openalex.org/W2913835466"],"abstract_inverted_index":{"Introduction":[0],"Major":[1,221],"glossectomy":[2,33,66,222],"is":[3],"the":[4,15,19,74,85,93,116,237],"treatment":[5],"of":[6,21,47,78,84,95,126,147,236],"choice":[7],"in":[8,18,56,73,105],"locally":[9],"advanced":[10,82,234],"tongue":[11,87,239],"cancer.":[12],"It":[13],"remains":[14],"only":[16],"option":[17,229],"presence":[20],"recurrent":[22],"or":[23,243],"residual":[24],"disease.":[25],"The":[26,45,76,108],"long-term":[27],"outcomes":[28,55],"for":[29,151,189,230],"patients":[30,57,63,80,121,132,232],"undergoing":[31,58,64],"major":[32,59,65],"have":[34],"traditionally":[35],"been":[36],"poor,":[37],"with":[38,81,202,218,233,240],"significant":[39,187],"morbidity":[40],"and":[41,69,99,137,159,166,193,212],"poor":[42,175,190,203,219],"oncological":[43,54],"outcomes.":[44,220],"aim":[46],"this":[48],"study":[49],"was":[50,112,185,199],"to":[51],"report":[52],"on":[53,205],"glossectomy.":[60],"Methods":[61],"All":[62,90],"between":[67],"2014":[68],"2018":[70],"were":[71,88,91,123,128,163,216],"included":[72],"study.":[75],"data":[77],"85":[79],"carcinoma":[83,235],"oral":[86,238],"evaluated.":[89],"under":[92],"care":[94],"a":[96,144,172,186,227],"single":[97],"surgical":[98],"reconstructive":[100],"team":[101],"at":[102],"two":[103],"hospitals":[104],"Mumbai.":[106],"Results":[107],"median":[109,145],"patient":[110],"age":[111],"45":[113],"years.":[114],"At":[115,143],"most":[117],"recent":[118],"follow-up,":[119],"55":[120],"(65%)":[122],"alive,":[124],"47":[125],"whom":[127],"disease":[129,155,247],"free.":[130],"Twenty-nine":[131],"(34%)":[133],"had":[134,140],"locoregional":[135,153,194],"recurrence":[136],"twenty-five":[138],"(29%)":[139],"distant":[141],"metastasis.":[142],"follow-up":[146],"19":[148],"months,":[149],"rates":[150],"2-year":[152],"control,":[154],"free":[156],"survival":[157,161],"(DFS)":[158],"overall":[160],"(OS)":[162],"69%,":[164],"61%":[165],"62%":[167],"respectively.":[168],"Perinodal":[169],"extension":[170],"demonstrated":[171],"trend":[173],"towards":[174],"DFS":[176,192],"(p=0.060),":[177],"as":[178,226],"did":[179],"perineural":[180],"invasion":[181],"(p=0.055).":[182],"Node":[183,210],"positivity":[184,211],"factor":[188],"OS,":[191],"control.":[195],"Multiple":[196],"node":[197,214,241],"involvement":[198,215],"significantly":[200],"associated":[201,217],"OS":[204],"multivariate":[206],"analysis":[207],"(p=0.002).":[208],"Conclusions":[209],"multiple":[213],"may":[223],"be":[224],"offered":[225],"curative":[228],"selected":[231],"negative":[242],"limited":[244],"neck":[245],"nodal":[246],"(N1).":[248]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":5},{"year":2024,"cited_by_count":1}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2020-05-29T00:00:00"}