{"id":"https://openalex.org/W3028005503","doi":"https://doi.org/10.1016/j.jcyt.2020.03.241","title":"Effects of short-chain fatty acid on proliferation, metabolic poise, and activation capacity of T cells","display_name":"Effects of short-chain fatty acid on proliferation, metabolic poise, and activation capacity of T cells","publication_year":2020,"publication_date":"2020-05-01","ids":{"openalex":"https://openalex.org/W3028005503","doi":"https://doi.org/10.1016/j.jcyt.2020.03.241","mag":"3028005503"},"language":"en","primary_location":{"id":"doi:10.1016/j.jcyt.2020.03.241","doi":"https://doi.org/10.1016/j.jcyt.2020.03.241","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.jcyt.2020.03.241","pdf_url":null,"source":{"id":"https://openalex.org/S36838616","display_name":"Cytotherapy","issn_l":"1465-3249","issn":["1465-3249","1477-2566"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cytotherapy","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5024464289","display_name":"Yoonseok Kam","orcid":"https://orcid.org/0000-0003-4712-9058","observed_orcids":["https://orcid.org/0000-0003-4712-9058"]},"institutions":[{"id":"https://openalex.org/I138285227","display_name":"Agilent Technologies (United States)","ror":"https://ror.org/02tryst02","country_code":"US","type":"company","lineage":["https://openalex.org/I138285227"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Y. Kam","raw_affiliation_strings":["Agilent Technologies, Lexington, Massachusetts, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Agilent Technologies, Lexington, Massachusetts, United States","institution_ids":["https://openalex.org/I138285227"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054034210","display_name":"Lisa Winer","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I138285227","display_name":"Agilent Technologies (United States)","ror":"https://ror.org/02tryst02","country_code":"US","type":"company","lineage":["https://openalex.org/I138285227"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"L. Winer","raw_affiliation_strings":["Agilent Technologies, Lexington, Massachusetts, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Agilent Technologies, Lexington, Massachusetts, United States","institution_ids":["https://openalex.org/I138285227"]}]},{"author_position":"middle","author":{"id":null,"display_name":"N. Romero","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I138285227","display_name":"Agilent Technologies (United States)","ror":"https://ror.org/02tryst02","country_code":"US","type":"company","lineage":["https://openalex.org/I138285227"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"N. Romero","raw_affiliation_strings":["Agilent Technologies, Lexington, Massachusetts, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Agilent Technologies, Lexington, Massachusetts, United States","institution_ids":["https://openalex.org/I138285227"]}]},{"author_position":"last","author":{"id":null,"display_name":"J. Hynes","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I138285227","display_name":"Agilent Technologies (United States)","ror":"https://ror.org/02tryst02","country_code":"US","type":"company","lineage":["https://openalex.org/I138285227"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"J. Hynes","raw_affiliation_strings":["Agilent Technologies, Lexington, Massachusetts, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Agilent Technologies, Lexington, Massachusetts, United States","institution_ids":["https://openalex.org/I138285227"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5024464289"],"corresponding_institution_ids":["https://openalex.org/I138285227"],"apc_list":{"value":3300,"currency":"USD","value_usd":3300},"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.05259087,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":92,"max":95},"biblio":{"volume":"22","issue":"5","first_page":"S127","last_page":"S127"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10031","display_name":"T-cell and B-cell Immunology","score":0.8310999870300293,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10031","display_name":"T-cell and B-cell Immunology","score":0.8310999870300293,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10066","display_name":"Gut microbiota and health","score":0.10700000077486038,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11313","display_name":"Immune cells in cancer","score":0.006899999920278788,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/short-chain-fatty-acids","display_name":"short-chain fatty acids","score":1.0},{"id":"https://openalex.org/keywords/butyrate","display_name":"butyrate","score":1.0},{"id":"https://openalex.org/keywords/t-cell-metabolism","display_name":"T cell metabolism","score":0.9919999837875366},{"id":"https://openalex.org/keywords/t-cell-activation","display_name":"T cell activation","score":0.6380000114440918},{"id":"https://openalex.org/keywords/glycolysis","display_name":"glycolysis","score":0.8429999947547913},{"id":"https://openalex.org/keywords/oxidative-phosphorylation","display_name":"oxidative phosphorylation","score":0.9919999837875366},{"id":"https://openalex.org/keywords/aerobic-metabolism","display_name":"aerobic metabolism","score":0.6840000152587891},{"id":"https://openalex.org/keywords/t-cell-proliferation","display_name":"T cell proliferation","score":0.8029999732971191},{"id":"https://openalex.org/keywords/t-cell-restimulation","display_name":"T cell reactivation","score":0.7229999899864197},{"id":"https://openalex.org/keywords/gut-microbiota","display_name":"gut microbiota","score":0.625},{"id":"https://openalex.org/keywords/cd8-t-cells","display_name":"CD8+ T cells","score":0.8790000081062317},{"id":"https://openalex.org/keywords/memory-t-cells","display_name":"memory T cells","score":0.8050000071525574},{"id":"https://openalex.org/keywords/t-cell-exhaustion","display_name":"T cell exhaustion","score":0.7570000290870667}],"concepts":[{"id":"https://openalex.org/C2776979534","wikidata":"https://www.wikidata.org/wiki/Q193213","display_name":"Butyrate","level":3,"score":0.8608702421188354},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.6569811701774597},{"id":"https://openalex.org/C55885012","wikidata":"https://www.wikidata.org/wiki/Q4750801","display_name":"Anaerobic glycolysis","level":4,"score":0.6158906817436218},{"id":"https://openalex.org/C20251656","wikidata":"https://www.wikidata.org/wiki/Q162643","display_name":"Glycolysis","level":3,"score":0.5992288589477539},{"id":"https://openalex.org/C57600042","wikidata":"https://www.wikidata.org/wiki/Q227564","display_name":"Oxidative phosphorylation","level":2,"score":0.5867083072662354},{"id":"https://openalex.org/C2776090121","wikidata":"https://www.wikidata.org/wiki/Q193529","display_name":"T cell","level":3,"score":0.5552852153778076},{"id":"https://openalex.org/C62112901","wikidata":"https://www.wikidata.org/wiki/Q189159","display_name":"Cell growth","level":2,"score":0.4894057810306549},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.48871541023254395},{"id":"https://openalex.org/C167672396","wikidata":"https://www.wikidata.org/wiki/Q417800","display_name":"CD8","level":3,"score":0.4782634973526001},{"id":"https://openalex.org/C82714985","wikidata":"https://www.wikidata.org/wiki/Q306213","display_name":"Beta oxidation","level":3,"score":0.47122323513031006},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.46588531136512756},{"id":"https://openalex.org/C2776991927","wikidata":"https://www.wikidata.org/wiki/Q14860867","display_name":"Fatty acid metabolism","level":3,"score":0.44772204756736755},{"id":"https://openalex.org/C62231903","wikidata":"https://www.wikidata.org/wiki/Q1057","display_name":"Metabolism","level":2,"score":0.40950071811676025},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.3967714309692383},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3680400848388672},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.1820923089981079},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.15652713179588318},{"id":"https://openalex.org/C100544194","wikidata":"https://www.wikidata.org/wiki/Q41760","display_name":"Fermentation","level":2,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1016/j.jcyt.2020.03.241","doi":"https://doi.org/10.1016/j.jcyt.2020.03.241","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.jcyt.2020.03.241","pdf_url":null,"source":{"id":"https://openalex.org/S36838616","display_name":"Cytotherapy","issn_l":"1465-3249","issn":["1465-3249","1477-2566"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cytotherapy","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9391000270843506}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2956016709","https://openalex.org/W4288045620","https://openalex.org/W3125090852","https://openalex.org/W4313365919","https://openalex.org/W4413326936","https://openalex.org/W2152529866","https://openalex.org/W3014584997","https://openalex.org/W2944782439","https://openalex.org/W4313359403","https://openalex.org/W7160418886"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2020-05-29T00:00:00"}