{"id":"https://openalex.org/W302750429","doi":null,"title":"Comparison of a Tetravalent Single-Chain Antibody-Streptavidin Fusion Protein and an Antibody-Streptavidin Chemical Conjugate for Pretargeted Anti-CD20 Radioimmunotherapy of B-cell Lymphomas Running Title: \"Optimizing Pretargeted Radioimmunotherapy for CD20+ Lymphomas\"","display_name":"Comparison of a Tetravalent Single-Chain Antibody-Streptavidin Fusion Protein and an Antibody-Streptavidin Chemical Conjugate for Pretargeted Anti-CD20 Radioimmunotherapy of B-cell Lymphomas Running Title: \"Optimizing Pretargeted Radioimmunotherapy for CD20+ Lymphomas\"","publication_year":2016,"publication_date":"2016-01-01","ids":{"openalex":"https://openalex.org/W302750429","mag":"302750429"},"language":"en","primary_location":{"id":"mag:302750429","doi":null,"is_oa":false,"landing_page_url":"http://www.bloodjournal.org/content/bloodjournal/early/2006/03/23/blood-2005-11-4327.full.pdf?sso-checked=true","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5040412322","display_name":"John M. Pagel","orcid":"https://orcid.org/0000-0001-5745-8125","observed_orcids":["https://orcid.org/0000-0001-5745-8125","https://orcid.org/0000-0003-2875-4878"]},"institutions":[{"id":"https://openalex.org/I4210089486","display_name":"Fred Hutch Cancer Center","ror":"https://ror.org/007ps6h72","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210089486"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"John M. Pagel","raw_affiliation_strings":["Fred Hutchinson Cancer Research Center"],"raw_orcid":"https://orcid.org/0000-0001-5745-8125","affiliations":[{"raw_affiliation_string":"Fred Hutchinson Cancer Research Center","institution_ids":["https://openalex.org/I4210089486"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053467199","display_name":"Yukang Lin","orcid":"https://orcid.org/0000-0001-8586-8682","observed_orcids":["https://orcid.org/0000-0001-8586-8682"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Yukang Lin","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-8586-8682","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072666392","display_name":"Nathan Hedin","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Nathan Hedin","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056558805","display_name":"Anastasia Pantelias","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Anastasia Pantelias","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111700377","display_name":"Donald B. Axworthy","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Donald B. Axworthy","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"Diane","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Diane","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037090747","display_name":"Don K. Hamlin","orcid":"https://orcid.org/0009-0009-5302-8166","observed_orcids":["https://orcid.org/0009-0009-5302-8166"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Don K. Hamlin","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009266851","display_name":"D. Scott Wilbur","orcid":"https://orcid.org/0000-0001-7767-8731","observed_orcids":["https://orcid.org/0000-0001-7767-8731"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"D. Scott Wilbur","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-7767-8731","affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5023180146","display_name":"Oliver W. Press","orcid":"https://orcid.org/0000-0002-3147-8037","observed_orcids":["https://orcid.org/0000-0002-3147-8037"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Oliver W. Press","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-3147-8037","affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.00038882,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11395","display_name":"Radiopharmaceutical Chemistry and Applications","score":0.9779999852180481,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11395","display_name":"Radiopharmaceutical Chemistry and Applications","score":0.9779999852180481,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10185","display_name":"Lymphoma Diagnosis and Treatment","score":0.013100000098347664,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11016","display_name":"Monoclonal and Polyclonal Antibodies Research","score":0.005400000140070915,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/pretargeted-radioimmunotherapy","display_name":"pretargeted radioimmunotherapy","score":0.9139999747276306},{"id":"https://openalex.org/keywords/cd20","display_name":"CD20","score":0.847000002861023},{"id":"https://openalex.org/keywords/b-cell-lymphoma","display_name":"B-cell lymphoma","score":0.9539999961853027},{"id":"https://openalex.org/keywords/single-chain-antibody","display_name":"single-chain antibody","score":0.7850000262260437},{"id":"https://openalex.org/keywords/streptavidin","display_name":"streptavidin","score":0.7620000243186951},{"id":"https://openalex.org/keywords/radioimmunodetection","display_name":"radioimmunodetection","score":0.5099999904632568}],"concepts":[{"id":"https://openalex.org/C2776146153","wikidata":"https://www.wikidata.org/wiki/Q7281276","display_name":"Radioimmunotherapy","level":4,"score":0.874549388885498},{"id":"https://openalex.org/C2776190903","wikidata":"https://www.wikidata.org/wiki/Q421817","display_name":"Streptavidin","level":3,"score":0.6935844421386719},{"id":"https://openalex.org/C197336794","wikidata":"https://www.wikidata.org/wiki/Q5161150","display_name":"Conjugate","level":2,"score":0.595477819442749},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.508300244808197},{"id":"https://openalex.org/C123894998","wikidata":"https://www.wikidata.org/wiki/Q425158","display_name":"Fusion protein","level":4,"score":0.41074198484420776},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3802536129951477},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3636733889579773},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.27716317772865295},{"id":"https://openalex.org/C542903549","wikidata":"https://www.wikidata.org/wiki/Q422248","display_name":"Monoclonal antibody","level":3,"score":0.19637760519981384},{"id":"https://openalex.org/C2778204606","wikidata":"https://www.wikidata.org/wiki/Q181354","display_name":"Biotin","level":2,"score":0.17173537611961365},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.16924047470092773},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.15793374180793762},{"id":"https://openalex.org/C40767141","wikidata":"https://www.wikidata.org/wiki/Q285697","display_name":"Recombinant DNA","level":3,"score":0.15387046337127686},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.07453674077987671},{"id":"https://openalex.org/C134306372","wikidata":"https://www.wikidata.org/wiki/Q7754","display_name":"Mathematical analysis","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"mag:302750429","doi":null,"is_oa":false,"landing_page_url":"http://www.bloodjournal.org/content/bloodjournal/early/2006/03/23/blood-2005-11-4327.full.pdf?sso-checked=true","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.8048999905586243,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":45,"referenced_works":["https://openalex.org/W1512221515","https://openalex.org/W1563765846","https://openalex.org/W1573890015","https://openalex.org/W1575226163","https://openalex.org/W1821306440","https://openalex.org/W1847108833","https://openalex.org/W1869307723","https://openalex.org/W1883499946","https://openalex.org/W1952970584","https://openalex.org/W1979401181","https://openalex.org/W1982485975","https://openalex.org/W1983649348","https://openalex.org/W1986899975","https://openalex.org/W2004224153","https://openalex.org/W2006327509","https://openalex.org/W2007734777","https://openalex.org/W2014654561","https://openalex.org/W2019506220","https://openalex.org/W2029318296","https://openalex.org/W2030765561","https://openalex.org/W2058426435","https://openalex.org/W2087695516","https://openalex.org/W2093620219","https://openalex.org/W2107861907","https://openalex.org/W2107895289","https://openalex.org/W2107990794","https://openalex.org/W2110646221","https://openalex.org/W2116671252","https://openalex.org/W2118833600","https://openalex.org/W2128997140","https://openalex.org/W2131748204","https://openalex.org/W2132128887","https://openalex.org/W2146102054","https://openalex.org/W2152526200","https://openalex.org/W2165573190","https://openalex.org/W2169072424","https://openalex.org/W2171940041","https://openalex.org/W2200499915","https://openalex.org/W2215316452","https://openalex.org/W2256690185","https://openalex.org/W2265959190","https://openalex.org/W2286405748","https://openalex.org/W2320751441","https://openalex.org/W2379953517","https://openalex.org/W2554555085"],"related_works":["https://openalex.org/W1982849241","https://openalex.org/W2200499915","https://openalex.org/W2107861907","https://openalex.org/W2030765561","https://openalex.org/W2138994942","https://openalex.org/W2069441856","https://openalex.org/W2151119213","https://openalex.org/W7095724811","https://openalex.org/W1987890709","https://openalex.org/W2165573190"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-10-16T09:59:22.235173","created_date":"2016-06-24T00:00:00"}