{"id":"https://openalex.org/W3025820394","doi":null,"title":"[HYPERTENSION OF PREGNANCY ASSOCIATED WITH HYPERGOMOCYSTEINEMIA OF THE FIRST TRIMESTER OF PREGNANCY].","display_name":"[HYPERTENSION OF PREGNANCY ASSOCIATED WITH HYPERGOMOCYSTEINEMIA OF THE FIRST TRIMESTER OF PREGNANCY].","publication_year":2018,"publication_date":"2018-03-01","ids":{"openalex":"https://openalex.org/W3025820394","mag":"3025820394","pmid":"https://pubmed.ncbi.nlm.nih.gov/29697379"},"language":"ru","primary_location":{"id":"pmid:29697379","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/29697379","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Georgian medical news","raw_type":"Journal Article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5037325157","display_name":"Akylbek Tussupkaliyev","orcid":"https://orcid.org/0000-0002-1228-7390","observed_orcids":["https://orcid.org/0000-0002-1228-7390","https://orcid.org/0000-0002-2956-7524"]},"institutions":[{"id":"https://openalex.org/I131736796","display_name":"Lithuanian University of Health Sciences","ror":"https://ror.org/0069bkg23","country_code":"LT","type":"education","lineage":["https://openalex.org/I131736796"]},{"id":"https://openalex.org/I4210130920","display_name":"West Kazakhstan Marat Ospanov State Medical University","ror":"https://ror.org/04ehpm154","country_code":"KZ","type":"education","lineage":["https://openalex.org/I4210130920"]}],"countries":["KZ","LT"],"is_corresponding":false,"raw_author_name":"Ak Tussupkaliyev","raw_affiliation_strings":["West Kazakhstan State Medical University named after Marat Ospanov, Department of Obstetrics and Gynecology \u21162, Aktobe, Kazakhstan; Lithuanian University of Health Sciences, Department of Obstetrics and Gynecology, Kaunas, Lithuania"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"West Kazakhstan State Medical University named after Marat Ospanov, Department of Obstetrics and Gynecology \u21162, Aktobe, Kazakhstan; Lithuanian University of Health Sciences, Department of Obstetrics and Gynecology, Kaunas, Lithuania","institution_ids":["https://openalex.org/I131736796","https://openalex.org/I4210130920"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006445822","display_name":"Andrey N. Gaiday","orcid":"https://orcid.org/0000-0001-7629-8737","observed_orcids":["https://orcid.org/0000-0001-7629-8737"]},"institutions":[{"id":"https://openalex.org/I131736796","display_name":"Lithuanian University of Health Sciences","ror":"https://ror.org/0069bkg23","country_code":"LT","type":"education","lineage":["https://openalex.org/I131736796"]},{"id":"https://openalex.org/I4210130920","display_name":"West Kazakhstan Marat Ospanov State Medical University","ror":"https://ror.org/04ehpm154","country_code":"KZ","type":"education","lineage":["https://openalex.org/I4210130920"]}],"countries":["KZ","LT"],"is_corresponding":false,"raw_author_name":"A Gaiday","raw_affiliation_strings":["West Kazakhstan State Medical University named after Marat Ospanov, Department of Obstetrics and Gynecology \u21162, Aktobe, Kazakhstan; Lithuanian University of Health Sciences, Department of Obstetrics and Gynecology, Kaunas, Lithuania"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"West Kazakhstan State Medical University named after Marat Ospanov, Department of Obstetrics and Gynecology \u21162, Aktobe, Kazakhstan; Lithuanian University of Health Sciences, Department of Obstetrics and Gynecology, Kaunas, Lithuania","institution_ids":["https://openalex.org/I131736796","https://openalex.org/I4210130920"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048568548","display_name":"Saule Bermagambetova","orcid":"https://orcid.org/0000-0002-5018-0498","observed_orcids":["https://orcid.org/0000-0002-5018-0498"]},"institutions":[{"id":"https://openalex.org/I131736796","display_name":"Lithuanian University of Health Sciences","ror":"https://ror.org/0069bkg23","country_code":"LT","type":"education","lineage":["https://openalex.org/I131736796"]},{"id":"https://openalex.org/I4210130920","display_name":"West Kazakhstan Marat Ospanov State Medical University","ror":"https://ror.org/04ehpm154","country_code":"KZ","type":"education","lineage":["https://openalex.org/I4210130920"]}],"countries":["KZ","LT"],"is_corresponding":false,"raw_author_name":"S Bermagambetova","raw_affiliation_strings":["West Kazakhstan State Medical University named after Marat Ospanov, Department of Obstetrics and Gynecology \u21162, Aktobe, Kazakhstan; Lithuanian University of Health Sciences, Department of Obstetrics and Gynecology, Kaunas, Lithuania"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"West Kazakhstan State Medical University named after Marat Ospanov, Department of Obstetrics and Gynecology \u21162, Aktobe, Kazakhstan; Lithuanian University of Health Sciences, Department of Obstetrics and Gynecology, Kaunas, Lithuania","institution_ids":["https://openalex.org/I131736796","https://openalex.org/I4210130920"]}]},{"author_position":"last","author":{"id":null,"display_name":"R Aniuliene","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I131736796","display_name":"Lithuanian University of Health Sciences","ror":"https://ror.org/0069bkg23","country_code":"LT","type":"education","lineage":["https://openalex.org/I131736796"]},{"id":"https://openalex.org/I4210130920","display_name":"West Kazakhstan Marat Ospanov State Medical University","ror":"https://ror.org/04ehpm154","country_code":"KZ","type":"education","lineage":["https://openalex.org/I4210130920"]}],"countries":["KZ","LT"],"is_corresponding":false,"raw_author_name":"R Aniuliene","raw_affiliation_strings":["West Kazakhstan State Medical University named after Marat Ospanov, Department of Obstetrics and Gynecology \u21162, Aktobe, Kazakhstan; Lithuanian University of Health Sciences, Department of Obstetrics and Gynecology, Kaunas, Lithuania"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"West Kazakhstan State Medical University named after Marat Ospanov, Department of Obstetrics and Gynecology \u21162, Aktobe, Kazakhstan; Lithuanian University of Health Sciences, Department of Obstetrics and Gynecology, Kaunas, Lithuania","institution_ids":["https://openalex.org/I131736796","https://openalex.org/I4210130920"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.8147,"has_fulltext":false,"cited_by_count":5,"citation_normalized_percentile":{"value":0.76989087,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":95},"biblio":{"volume":null,"issue":"276","first_page":"40","last_page":"46"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10290","display_name":"Pregnancy and preeclampsia studies","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2729","display_name":"Obstetrics and Gynecology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10290","display_name":"Pregnancy and preeclampsia studies","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2729","display_name":"Obstetrics and Gynecology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10499","display_name":"Folate and B Vitamins Research","score":0.0008999999845400453,"subfield":{"id":"https://openalex.org/subfields/2916","display_name":"Nutrition and Dietetics"},"field":{"id":"https://openalex.org/fields/29","display_name":"Nursing"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12464","display_name":"Neurological Complications and Syndromes","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hyperhomocysteinemia","display_name":"hyperhomocysteinemia","score":0.921999990940094},{"id":"https://openalex.org/keywords/gestational-hypertension","display_name":"gestational hypertension","score":0.8019999861717224},{"id":"https://openalex.org/keywords/first-trimester","display_name":"first trimester","score":0.8019999861717224},{"id":"https://openalex.org/keywords/preeclampsia","display_name":"preeclampsia","score":0.8140000104904175},{"id":"https://openalex.org/keywords/miscarriage","display_name":"miscarriage","score":0.8640000224113464},{"id":"https://openalex.org/keywords/preterm-birth","display_name":"preterm birth","score":0.8309999704360962},{"id":"https://openalex.org/keywords/intrauterine-growth-restriction","display_name":"fetal growth restriction","score":0.9570000171661377},{"id":"https://openalex.org/keywords/congenital-malformations","display_name":"congenital malformations","score":0.9760000109672546},{"id":"https://openalex.org/keywords/hellp-syndrome","display_name":"HELLP syndrome","score":0.9369999766349792},{"id":"https://openalex.org/keywords/eclampsia","display_name":"eclampsia","score":0.8259999752044678}],"concepts":[{"id":"https://openalex.org/C2779234561","wikidata":"https://www.wikidata.org/wiki/Q11995","display_name":"Pregnancy","level":2,"score":0.8538505434989929},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8437715768814087},{"id":"https://openalex.org/C2777218350","wikidata":"https://www.wikidata.org/wiki/Q61335","display_name":"Preeclampsia","level":3,"score":0.7880619764328003},{"id":"https://openalex.org/C131872663","wikidata":"https://www.wikidata.org/wiki/Q5284418","display_name":"Obstetrics","level":1,"score":0.7407686710357666},{"id":"https://openalex.org/C172680121","wikidata":"https://www.wikidata.org/wiki/Q26513","display_name":"Fetus","level":3,"score":0.7018487453460693},{"id":"https://openalex.org/C2777583542","wikidata":"https://www.wikidata.org/wiki/Q1519482","display_name":"Gestational hypertension","level":4,"score":0.6007598638534546},{"id":"https://openalex.org/C46973012","wikidata":"https://www.wikidata.org/wiki/Q28627","display_name":"Gestation","level":3,"score":0.5389668941497803},{"id":"https://openalex.org/C2781276381","wikidata":"https://www.wikidata.org/wiki/Q552348","display_name":"Eclampsia","level":3,"score":0.5138216614723206},{"id":"https://openalex.org/C2778376644","wikidata":"https://www.wikidata.org/wiki/Q2253111","display_name":"Gestational age","level":3,"score":0.5035228133201599},{"id":"https://openalex.org/C2780938740","wikidata":"https://www.wikidata.org/wiki/Q1298973","display_name":"Small for gestational age","level":4,"score":0.4863343834877014},{"id":"https://openalex.org/C2778642596","wikidata":"https://www.wikidata.org/wiki/Q8452","display_name":"Abortion","level":3,"score":0.4810655117034912},{"id":"https://openalex.org/C188816634","wikidata":"https://www.wikidata.org/wiki/Q2113324","display_name":"Prospective cohort study","level":2,"score":0.47693246603012085},{"id":"https://openalex.org/C2777090595","wikidata":"https://www.wikidata.org/wiki/Q192466","display_name":"Homocysteine","level":2,"score":0.4584921896457672},{"id":"https://openalex.org/C2778780700","wikidata":"https://www.wikidata.org/wiki/Q1671598","display_name":"Intrauterine growth restriction","level":4,"score":0.4385707974433899},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.19659382104873657},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.18786999583244324},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.04413697123527527},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004461","descriptor_name":"Eclampsia","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D004461","descriptor_name":"Eclampsia","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006710","descriptor_name":"Homocysteine","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011225","descriptor_name":"Pre-Eclampsia","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D011225","descriptor_name":"Pre-Eclampsia","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D011247","descriptor_name":"Pregnancy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011261","descriptor_name":"Pregnancy Trimester, First","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011379","descriptor_name":"Prognosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011446","descriptor_name":"Prospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017359","descriptor_name":"HELLP Syndrome","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D017359","descriptor_name":"HELLP Syndrome","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D020138","descriptor_name":"Hyperhomocysteinemia","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D020138","descriptor_name":"Hyperhomocysteinemia","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D046110","descriptor_name":"Hypertension, Pregnancy-Induced","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D046110","descriptor_name":"Hypertension, Pregnancy-Induced","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true}],"locations_count":3,"locations":[{"id":"pmid:29697379","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/29697379","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Georgian medical news","raw_type":"Journal Article"},{"id":"pmh:oai:lsmu.lt:20.500.12512/19852","doi":null,"is_oa":false,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pubmed/29697379","pdf_url":null,"source":{"id":"https://openalex.org/S7407055191","display_name":"Lithuanian University of Health Sciences","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"journal article"},{"id":"mag:3025820394","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/29697379","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9940000176429749,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2030963729","https://openalex.org/W7098400933","https://openalex.org/W2965499858","https://openalex.org/W2540866998","https://openalex.org/W3013084233","https://openalex.org/W2037748478","https://openalex.org/W757656255","https://openalex.org/W7169848089","https://openalex.org/W2770393519","https://openalex.org/W2117797399"],"abstract_inverted_index":{"In":[0],"this":[1],"study,":[2],"the":[3,34,46,57,63,84,110,121,136,165,172],"association":[4],"of":[5,11,26,31,45,59,79,104,107,120,135,143,171],"high":[6,92],"homocysteine":[7,60,144],"concentrations":[8,93],"(>10":[9,94],"\u03bcmol/L)":[10,95],"pregnant":[12],"women":[13],"with":[14,66,91],"hypertensive":[15],"disorders":[16],"during":[17],"pregnancy":[18,32,108],"was":[19,53],"studied,":[20],"as":[21,23,29],"well":[22],"other":[24],"complications":[25,103],"pregnancy,":[27],"such":[28],"loss":[30,106],"in":[33,109,164],"first":[35,111],"half,":[36,112],"premature":[37,113,151],"birth,":[38,114,152],"intrauterine":[39,169],"growth":[40,170],"retardation,":[41],"congenital":[42,118,174],"malformations":[43,119],"development":[44],"fetus.":[47],"A":[48],"single-center":[49],"prospective":[50],"cohort":[51],"study":[52,137],"conducted.":[54],"Depending":[55],"on":[56],"concentration":[58],"detected":[61],"by":[62],"immunoenzyme":[64],"assay":[65],"monoclonal":[67],"antibodies":[68],"Homocysteine":[69],"EIA":[70],"ELISA":[71],"(Axis-Shield":[72],"Diagnostics":[73],"Ltd,":[74],"Scotland),":[75],"for":[76,167],"a":[77,141],"period":[78],"up":[80],"to":[81],"14":[82],"weeks,":[83],"subjects":[85],"were":[86,161],"divided":[87],"into":[88],"2":[89],"groups:":[90],"and":[96,126,130],"normal":[97],"levels":[98],"(<10":[99],"\u03bcmol/L).":[100],"We":[101],"controlled":[102],"pregnancy:":[105],"delayed":[115],"fetal":[116],"growth,":[117],"fetus,":[122,173],"gestational":[123,153],"hypertension,":[124,154],"mild":[125,155],"severe":[127,176],"preeclampsia,":[128],"eclampsia":[129],"HELLP":[131],"syndrome.":[132],"The":[133],"results":[134],"showed":[138],"that":[139],"at":[140],"level":[142],"I":[145],"trimester":[146],">10":[147],"\u03bcmol/l":[148],"spontaneous":[149],"abortion,":[150],"preeclampsia":[156],"develop":[157],"more":[158],"often.":[159],"There":[160],"no":[162],"differences":[163],"groups":[166],"delaying":[168],"malformations,":[175],"preeclampsia.":[177]},"counts_by_year":[{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2020,"cited_by_count":2},{"year":2018,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2020-05-21T00:00:00"}