{"id":"https://openalex.org/W30257615","doi":"https://doi.org/10.1016/s0735-1097(02)01859-4","title":"Heavy and light cigarette smokers have similar dysfunction of endothelial vasoregulatory activity","display_name":"Heavy and light cigarette smokers have similar dysfunction of endothelial vasoregulatory activity","publication_year":2002,"publication_date":"2002-06-01","ids":{"openalex":"https://openalex.org/W30257615","doi":"https://doi.org/10.1016/s0735-1097(02)01859-4","mag":"30257615","pmid":"https://pubmed.ncbi.nlm.nih.gov/12039488"},"language":"en","primary_location":{"id":"doi:10.1016/s0735-1097(02)01859-4","doi":"https://doi.org/10.1016/s0735-1097(02)01859-4","is_oa":true,"landing_page_url":"https://doi.org/10.1016/s0735-1097(02)01859-4","pdf_url":null,"source":{"id":"https://openalex.org/S60865174","display_name":"Journal of the American College of Cardiology","issn_l":"0735-1097","issn":["0735-1097","1558-3597"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the American College of Cardiology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://doi.org/10.1016/s0735-1097(02)01859-4","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5057018598","display_name":"Rajat S. Barua","orcid":"https://orcid.org/0000-0002-9642-5593","observed_orcids":["https://orcid.org/0000-0002-9642-5593"]},"institutions":[{"id":"https://openalex.org/I28290843","display_name":"University of Surrey","ror":"https://ror.org/00ks66431","country_code":"GB","type":"education","lineage":["https://openalex.org/I28290843"]},{"id":"https://openalex.org/I4210091615","display_name":"Saint Vincent's Catholic Medical Center","ror":"https://ror.org/00cwrhn79","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210091615"]}],"countries":["GB","US"],"is_corresponding":false,"raw_author_name":"Rajat S Barua","raw_affiliation_strings":["Department of Medicine, the Comprehensive Cardiovascular Center, Saint Vincent Catholic Medical Centers of New York, 170 West 12th Street, New York, NY 10011, USA","Saint Vincent Catholic Medical Centers, New York, New York, USA","the School of Biomedical and Life Sciences, University of Surrey, Guildford, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, the Comprehensive Cardiovascular Center, Saint Vincent Catholic Medical Centers of New York, 170 West 12th Street, New York, NY 10011, USA","institution_ids":["https://openalex.org/I4210091615"]},{"raw_affiliation_string":"Saint Vincent Catholic Medical Centers, New York, New York, USA","institution_ids":["https://openalex.org/I4210091615"]},{"raw_affiliation_string":"the School of Biomedical and Life Sciences, University of Surrey, Guildford, UK","institution_ids":["https://openalex.org/I28290843"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024067164","display_name":"John A. Ambrose","orcid":"https://orcid.org/0000-0002-7648-7586","observed_orcids":["https://orcid.org/0000-0002-7648-7586","https://orcid.org/0009-0004-7329-8167"]},"institutions":[{"id":"https://openalex.org/I4210091615","display_name":"Saint Vincent's Catholic Medical Center","ror":"https://ror.org/00cwrhn79","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210091615"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"John A Ambrose","raw_affiliation_strings":["Saint Vincent Catholic Medical Centers, New York, New York, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Saint Vincent Catholic Medical Centers, New York, New York, USA","institution_ids":["https://openalex.org/I4210091615"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090068888","display_name":"Lesley-Jane Eales-Reynolds","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I28290843","display_name":"University of Surrey","ror":"https://ror.org/00ks66431","country_code":"GB","type":"education","lineage":["https://openalex.org/I28290843"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Lesley-Jane Eales-Reynolds","raw_affiliation_strings":["the School of Biomedical and Life Sciences, University of Surrey, Guildford, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"the School of Biomedical and Life Sciences, University of Surrey, Guildford, UK","institution_ids":["https://openalex.org/I28290843"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041752181","display_name":"Mary C. DeVoe","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210091615","display_name":"Saint Vincent's Catholic Medical Center","ror":"https://ror.org/00cwrhn79","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210091615"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mary C DeVoe","raw_affiliation_strings":["Saint Vincent Catholic Medical Centers, New York, New York, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Saint Vincent Catholic Medical Centers, New York, New York, USA","institution_ids":["https://openalex.org/I4210091615"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035874071","display_name":"John G. Zervas","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210091615","display_name":"Saint Vincent's Catholic Medical Center","ror":"https://ror.org/00cwrhn79","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210091615"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"John G Zervas","raw_affiliation_strings":["Saint Vincent Catholic Medical Centers, New York, New York, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Saint Vincent Catholic Medical Centers, New York, New York, USA","institution_ids":["https://openalex.org/I4210091615"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5109165982","display_name":"Dhanonjoy C. Saha","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210091615","display_name":"Saint Vincent's Catholic Medical Center","ror":"https://ror.org/00cwrhn79","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210091615"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Dhanonjoy C Saha","raw_affiliation_strings":["Saint Vincent Catholic Medical Centers, New York, New York, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Saint Vincent Catholic Medical Centers, New York, New York, USA","institution_ids":["https://openalex.org/I4210091615"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5024067164"],"corresponding_institution_ids":["https://openalex.org/I4210091615"],"apc_list":{"value":7166,"currency":"USD","value_usd":7166},"apc_paid":null,"fwci":3.8339,"has_fulltext":false,"cited_by_count":125,"citation_normalized_percentile":{"value":0.93116028,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":91,"max":99},"biblio":{"volume":"39","issue":"11","first_page":"1758","last_page":"1763"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10155","display_name":"Nitric Oxide and Endothelin Effects","score":0.9945999979972839,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10155","display_name":"Nitric Oxide and Endothelin Effects","score":0.9945999979972839,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10924","display_name":"Cardiovascular Health and Disease Prevention","score":0.0031999999191612005,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10060","display_name":"Smoking Behavior and Cessation","score":0.001500000013038516,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cigarette-smoking","display_name":"cigarette smoking","score":0.9739999771118164},{"id":"https://openalex.org/keywords/light-smokers","display_name":"light smokers","score":0.6610000133514404},{"id":"https://openalex.org/keywords/heavy-smokers","display_name":"heavy smokers","score":0.9869999885559082},{"id":"https://openalex.org/keywords/endothelial-dysfunction","display_name":"endothelial dysfunction","score":0.9110000133514404},{"id":"https://openalex.org/keywords/endothelium-dependent-vasodilation","display_name":"endothelium-dependent vasodilation","score":0.9369999766349792},{"id":"https://openalex.org/keywords/nitric-oxide","display_name":"nitric oxide","score":0.8029999732971191},{"id":"https://openalex.org/keywords/endothelin-1","display_name":"endothelin-1","score":0.9430000185966492},{"id":"https://openalex.org/keywords/endothelial-nitric-oxide-synthase","display_name":"endothelial nitric oxide synthase","score":0.968999981880188},{"id":"https://openalex.org/keywords/brachial-artery","display_name":"brachial artery","score":0.7250000238418579},{"id":"https://openalex.org/keywords/human-umbilical-vein-endothelial-cells","display_name":"human umbilical vein endothelial cells","score":0.8100000023841858},{"id":"https://openalex.org/keywords/dose-dependent-effects","display_name":"dose-dependent effects","score":0.6480000019073486},{"id":"https://openalex.org/keywords/cardiovascular-risk","display_name":"cardiovascular risk","score":0.578000009059906},{"id":"https://openalex.org/keywords/cotinine","display_name":"cotinine","score":0.48100000619888306},{"id":"https://openalex.org/keywords/pack-years","display_name":"pack-years","score":0.7990000247955322}],"concepts":[{"id":"https://openalex.org/C2778326061","wikidata":"https://www.wikidata.org/wiki/Q1761022","display_name":"Enos","level":4,"score":0.9211140871047974},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8023810982704163},{"id":"https://openalex.org/C2778024521","wikidata":"https://www.wikidata.org/wiki/Q55639806","display_name":"Basal (medicine)","level":3,"score":0.6711412668228149},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6258310079574585},{"id":"https://openalex.org/C120770815","wikidata":"https://www.wikidata.org/wiki/Q14859627","display_name":"Vasodilation","level":2,"score":0.5997182130813599},{"id":"https://openalex.org/C519581460","wikidata":"https://www.wikidata.org/wiki/Q207843","display_name":"Nitric oxide","level":2,"score":0.5816630125045776},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.5776100754737854},{"id":"https://openalex.org/C2780972559","wikidata":"https://www.wikidata.org/wiki/Q550061","display_name":"Endothelial dysfunction","level":2,"score":0.5641350746154785},{"id":"https://openalex.org/C2776992346","wikidata":"https://www.wikidata.org/wiki/Q111140","display_name":"Endothelium","level":2,"score":0.5153455138206482},{"id":"https://openalex.org/C2779547902","wikidata":"https://www.wikidata.org/wiki/Q28086552","display_name":"Nicotine","level":2,"score":0.4744219183921814},{"id":"https://openalex.org/C2777411675","wikidata":"https://www.wikidata.org/wiki/Q1232438","display_name":"Umbilical vein","level":3,"score":0.46873268485069275},{"id":"https://openalex.org/C2776319443","wikidata":"https://www.wikidata.org/wiki/Q421177","display_name":"Cotinine","level":3,"score":0.4432593882083893},{"id":"https://openalex.org/C2777622882","wikidata":"https://www.wikidata.org/wiki/Q417619","display_name":"Nitric oxide synthase","level":3,"score":0.3269526958465576},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.26884371042251587},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.15728795528411865},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.1391068398952484},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.07869714498519897}],"mesh":[{"descriptor_ui":"D001916","descriptor_name":"Brachial Artery","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D001916","descriptor_name":"Brachial Artery","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D004305","descriptor_name":"Dose-Response Relationship, Drug","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004730","descriptor_name":"Endothelium, Vascular","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D004730","descriptor_name":"Endothelium, Vascular","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009569","descriptor_name":"Nitric Oxide","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":true},{"descriptor_ui":"D012907","descriptor_name":"Smoking","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D014664","descriptor_name":"Vasodilation","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D019332","descriptor_name":"Endothelin-1","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1016/s0735-1097(02)01859-4","doi":"https://doi.org/10.1016/s0735-1097(02)01859-4","is_oa":true,"landing_page_url":"https://doi.org/10.1016/s0735-1097(02)01859-4","pdf_url":null,"source":{"id":"https://openalex.org/S60865174","display_name":"Journal of the American College of Cardiology","issn_l":"0735-1097","issn":["0735-1097","1558-3597"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the American College of Cardiology","raw_type":"journal-article"},{"id":"pmid:12039488","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/12039488","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the American College of Cardiology","raw_type":"Journal Article"},{"id":"pmh:oai:repository.uwl.ac.uk:5036","doi":null,"is_oa":false,"landing_page_url":"https://repository.uwl.ac.uk/id/eprint/5036/","pdf_url":null,"source":{"id":"https://openalex.org/S4306402477","display_name":"UWL Repository (University of West London)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I177463362","host_organization_name":"University of West London","host_organization_lineage":["https://openalex.org/I177463362"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Article"}],"best_oa_location":{"id":"doi:10.1016/s0735-1097(02)01859-4","doi":"https://doi.org/10.1016/s0735-1097(02)01859-4","is_oa":true,"landing_page_url":"https://doi.org/10.1016/s0735-1097(02)01859-4","pdf_url":null,"source":{"id":"https://openalex.org/S60865174","display_name":"Journal of the American College of Cardiology","issn_l":"0735-1097","issn":["0735-1097","1558-3597"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the American College of Cardiology","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9763000011444092,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":28,"referenced_works":["https://openalex.org/W1497880117","https://openalex.org/W1591330065","https://openalex.org/W1981690068","https://openalex.org/W1984003955","https://openalex.org/W1996242581","https://openalex.org/W2001997356","https://openalex.org/W2014149401","https://openalex.org/W2019405521","https://openalex.org/W2022158477","https://openalex.org/W2023712580","https://openalex.org/W2029034420","https://openalex.org/W2044634951","https://openalex.org/W2050025296","https://openalex.org/W2061465408","https://openalex.org/W2069377429","https://openalex.org/W2086811578","https://openalex.org/W2101556918","https://openalex.org/W2105541876","https://openalex.org/W2127384758","https://openalex.org/W2165968255","https://openalex.org/W2214786725","https://openalex.org/W2318881450","https://openalex.org/W2318963073","https://openalex.org/W2409234316","https://openalex.org/W2416774100","https://openalex.org/W2782019335","https://openalex.org/W4244089942","https://openalex.org/W4285719527"],"related_works":["https://openalex.org/W2127384758","https://openalex.org/W2433288053","https://openalex.org/W3008278748","https://openalex.org/W2023712580","https://openalex.org/W2921375446","https://openalex.org/W2048826963","https://openalex.org/W2143639519","https://openalex.org/W2014149401","https://openalex.org/W7096459517","https://openalex.org/W7096472714"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":8},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":3},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":6},{"year":2017,"cited_by_count":6},{"year":2016,"cited_by_count":6},{"year":2015,"cited_by_count":6},{"year":2014,"cited_by_count":8},{"year":2013,"cited_by_count":4},{"year":2012,"cited_by_count":8}],"updated_date":"2026-11-06T12:05:46.655746","created_date":"2016-06-24T00:00:00"}