{"id":"https://openalex.org/W3025613645","doi":"https://doi.org/10.1371/journal.pntd.0008319","title":"Prognostic factors for mortality among patients with visceral leishmaniasis in East Africa: Systematic review and meta-analysis","display_name":"Prognostic factors for mortality among patients with visceral leishmaniasis in East Africa: Systematic review and meta-analysis","publication_year":2020,"publication_date":"2020-05-15","ids":{"openalex":"https://openalex.org/W3025613645","doi":"https://doi.org/10.1371/journal.pntd.0008319","mag":"3025613645","pmid":"https://pubmed.ncbi.nlm.nih.gov/32413028","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/7255612"},"language":"en","primary_location":{"id":"doi:10.1371/journal.pntd.0008319","doi":"https://doi.org/10.1371/journal.pntd.0008319","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pntd.0008319","pdf_url":"https://journals.plos.org/plosntds/article/file?id=10.1371/journal.pntd.0008319&type=printable","source":{"id":"https://openalex.org/S46544255","display_name":"PLoS neglected tropical diseases","issn_l":"1935-2727","issn":["1935-2727","1935-2735"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-2","ki-jl-1","medline","norway-1","oarl","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLOS Neglected Tropical Diseases","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://journals.plos.org/plosntds/article/file?id=10.1371/journal.pntd.0008319&type=printable","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5032530849","display_name":"Charles Abongomera","orcid":"https://orcid.org/0000-0003-0353-7770","observed_orcids":["https://orcid.org/0000-0003-0353-7770"]},"institutions":[{"id":"https://openalex.org/I1328908458","display_name":"M\u00e9decins Sans Fronti\u00e8res","ror":"https://ror.org/045xrnk02","country_code":"UG","type":"nonprofit","lineage":["https://openalex.org/I1328908458","https://openalex.org/I4210128224"]},{"id":"https://openalex.org/I4210120243","display_name":"M\u00e9decins Sans Fronti\u00e8res","ror":"https://ror.org/01w1vg437","country_code":"ZA","type":"nonprofit","lineage":["https://openalex.org/I4210120243","https://openalex.org/I4210128224"]},{"id":"https://openalex.org/I4210155797","display_name":"M\u00e9decins Sans Fronti\u00e8res","ror":"https://ror.org/05g6deb76","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210128224","https://openalex.org/I4210155797"]},{"id":"https://openalex.org/I4210164708","display_name":"M\u00e9decins Sans Fronti\u00e8res","ror":"https://ror.org/0506t0t42","country_code":"FR","type":"nonprofit","lineage":["https://openalex.org/I4210128224","https://openalex.org/I4210164708"]},{"id":"https://openalex.org/I78281549","display_name":"Instituut voor Tropische Geneeskunde","ror":"https://ror.org/03xq4x896","country_code":"BE","type":"funder","lineage":["https://openalex.org/I78281549"]}],"countries":["BE","FR","UG","US","ZA"],"is_corresponding":true,"raw_author_name":"Charles Abongomera","raw_affiliation_strings":["Department of Clinical Sciences, Institute of Tropical Medicine, Antwerp, Belgium","M\u00e9decins Sans Fronti\u00e8res, Abdurafi, Ethiopia"],"raw_orcid":"https://orcid.org/0000-0003-0353-7770","affiliations":[{"raw_affiliation_string":"Department of Clinical Sciences, Institute of Tropical Medicine, Antwerp, Belgium","institution_ids":["https://openalex.org/I78281549"]},{"raw_affiliation_string":"M\u00e9decins Sans Fronti\u00e8res, Abdurafi, Ethiopia","institution_ids":["https://openalex.org/I1328908458","https://openalex.org/I4210120243","https://openalex.org/I4210155797","https://openalex.org/I4210164708"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049122701","display_name":"Saskia van Henten","orcid":"https://orcid.org/0000-0001-6627-0474","observed_orcids":["https://orcid.org/0000-0001-6627-0474"]},"institutions":[{"id":"https://openalex.org/I78281549","display_name":"Instituut voor Tropische Geneeskunde","ror":"https://ror.org/03xq4x896","country_code":"BE","type":"funder","lineage":["https://openalex.org/I78281549"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"Saskia van Henten","raw_affiliation_strings":["Department of Clinical Sciences, Institute of Tropical Medicine, Antwerp, Belgium"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Clinical Sciences, Institute of Tropical Medicine, Antwerp, Belgium","institution_ids":["https://openalex.org/I78281549"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071258464","display_name":"FLORIAN M. VOGT","orcid":"https://orcid.org/0000-0003-2686-3149","observed_orcids":["https://orcid.org/0000-0003-2686-3149"]},"institutions":[{"id":"https://openalex.org/I78281549","display_name":"Instituut voor Tropische Geneeskunde","ror":"https://ror.org/03xq4x896","country_code":"BE","type":"funder","lineage":["https://openalex.org/I78281549"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"Florian Vogt","raw_affiliation_strings":["Department of Clinical Sciences, Institute of Tropical Medicine, Antwerp, Belgium"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Clinical Sciences, Institute of Tropical Medicine, Antwerp, Belgium","institution_ids":["https://openalex.org/I78281549"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074786702","display_name":"Jozefien Buyze","orcid":"https://orcid.org/0000-0001-6780-380X","observed_orcids":["https://orcid.org/0000-0001-6780-380X"]},"institutions":[{"id":"https://openalex.org/I78281549","display_name":"Instituut voor Tropische Geneeskunde","ror":"https://ror.org/03xq4x896","country_code":"BE","type":"funder","lineage":["https://openalex.org/I78281549"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"Jozefien Buyze","raw_affiliation_strings":["Department of Clinical Sciences, Institute of Tropical Medicine, Antwerp, Belgium"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Clinical Sciences, Institute of Tropical Medicine, Antwerp, Belgium","institution_ids":["https://openalex.org/I78281549"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058285355","display_name":"Kristien Verdonck","orcid":"https://orcid.org/0000-0003-1153-4078","observed_orcids":["https://orcid.org/0000-0003-1153-4078"]},"institutions":[{"id":"https://openalex.org/I78281549","display_name":"Instituut voor Tropische Geneeskunde","ror":"https://ror.org/03xq4x896","country_code":"BE","type":"funder","lineage":["https://openalex.org/I78281549"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"Kristien Verdonck","raw_affiliation_strings":["Department of Public Health, Institute of Tropical Medicine, Antwerp, Belgium"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Public Health, Institute of Tropical Medicine, Antwerp, Belgium","institution_ids":["https://openalex.org/I78281549"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5045317610","display_name":"Johan van Griensven","orcid":"https://orcid.org/0000-0001-6581-2964","observed_orcids":["https://orcid.org/0000-0001-6581-2964"]},"institutions":[{"id":"https://openalex.org/I78281549","display_name":"Instituut voor Tropische Geneeskunde","ror":"https://ror.org/03xq4x896","country_code":"BE","type":"funder","lineage":["https://openalex.org/I78281549"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"Johan van Griensven","raw_affiliation_strings":["Department of Clinical Sciences, Institute of Tropical Medicine, Antwerp, Belgium"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Clinical Sciences, Institute of Tropical Medicine, Antwerp, Belgium","institution_ids":["https://openalex.org/I78281549"]}]}],"institutions":[],"countries_distinct_count":5,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5032530849"],"corresponding_institution_ids":["https://openalex.org/I1328908458","https://openalex.org/I4210120243","https://openalex.org/I4210155797","https://openalex.org/I4210164708","https://openalex.org/I78281549"],"apc_list":{"value":2350,"currency":"USD","value_usd":2350},"apc_paid":{"value":2350,"currency":"USD","value_usd":2350},"fwci":0.336,"has_fulltext":true,"cited_by_count":35,"citation_normalized_percentile":{"value":0.38001371,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":99},"biblio":{"volume":"14","issue":"5","first_page":"e0008319","last_page":"e0008319"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10823","display_name":"Research on Leishmaniasis Studies","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10823","display_name":"Research on Leishmaniasis Studies","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10890","display_name":"Trypanosoma species research and implications","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12107","display_name":"Leprosy Research and Treatment","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/visceral-leishmaniasis","display_name":"visceral leishmaniasis","score":1.0},{"id":"https://openalex.org/keywords/mortality","display_name":"mortality","score":0.7450000047683716},{"id":"https://openalex.org/keywords/prognostic-factors","display_name":"prognostic factors","score":1.0},{"id":"https://openalex.org/keywords/jaundice","display_name":"jaundice","score":0.8840000033378601},{"id":"https://openalex.org/keywords/hiv-coinfection","display_name":"HIV coinfection","score":0.8840000033378601},{"id":"https://openalex.org/keywords/tuberculosis","display_name":"tuberculosis","score":0.8159999847412109},{"id":"https://openalex.org/keywords/age","display_name":"age","score":0.37400001287460327},{"id":"https://openalex.org/keywords/edema","display_name":"edema","score":0.9739999771118164},{"id":"https://openalex.org/keywords/hemorrhage","display_name":"hemorrhage","score":0.9010000228881836},{"id":"https://openalex.org/keywords/anemia","display_name":"anemia","score":0.7239999771118164},{"id":"https://openalex.org/keywords/malnutrition","display_name":"malnutrition","score":0.8230000138282776},{"id":"https://openalex.org/keywords/spleen-size","display_name":"spleen size","score":0.8259999752044678},{"id":"https://openalex.org/keywords/east-africa","display_name":"East Africa","score":0.9490000009536743}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8580433130264282},{"id":"https://openalex.org/C2778689377","wikidata":"https://www.wikidata.org/wiki/Q2046113","display_name":"Visceral leishmaniasis","level":3,"score":0.603691577911377},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5795061588287354},{"id":"https://openalex.org/C95190672","wikidata":"https://www.wikidata.org/wiki/Q815382","display_name":"Meta-analysis","level":2,"score":0.5786769986152649},{"id":"https://openalex.org/C23131810","wikidata":"https://www.wikidata.org/wiki/Q818574","display_name":"Observational study","level":2,"score":0.569054126739502},{"id":"https://openalex.org/C156957248","wikidata":"https://www.wikidata.org/wiki/Q1862216","display_name":"Odds ratio","level":2,"score":0.4732763469219208},{"id":"https://openalex.org/C189708586","wikidata":"https://www.wikidata.org/wiki/Q1504425","display_name":"Systematic review","level":3,"score":0.46310991048812866},{"id":"https://openalex.org/C2779473830","wikidata":"https://www.wikidata.org/wiki/Q1540899","display_name":"MEDLINE","level":2,"score":0.42450982332229614},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.41984865069389343},{"id":"https://openalex.org/C2776555147","wikidata":"https://www.wikidata.org/wiki/Q331283","display_name":"Leishmaniasis","level":2,"score":0.39247530698776245},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.22125175595283508},{"id":"https://openalex.org/C199539241","wikidata":"https://www.wikidata.org/wiki/Q7748","display_name":"Law","level":1,"score":0.0},{"id":"https://openalex.org/C17744445","wikidata":"https://www.wikidata.org/wiki/Q36442","display_name":"Political science","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000081415","descriptor_name":"Clinical Decision Rules","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000351","descriptor_name":"Africa, Eastern","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002648","descriptor_name":"Child","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002675","descriptor_name":"Child, Preschool","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007223","descriptor_name":"Infant","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007231","descriptor_name":"Infant, Newborn","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007898","descriptor_name":"Leishmaniasis, Visceral","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D007898","descriptor_name":"Leishmaniasis, Visceral","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":true},{"descriptor_ui":"D007898","descriptor_name":"Leishmaniasis, Visceral","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011379","descriptor_name":"Prognosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055815","descriptor_name":"Young Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":5,"locations":[{"id":"doi:10.1371/journal.pntd.0008319","doi":"https://doi.org/10.1371/journal.pntd.0008319","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pntd.0008319","pdf_url":"https://journals.plos.org/plosntds/article/file?id=10.1371/journal.pntd.0008319&type=printable","source":{"id":"https://openalex.org/S46544255","display_name":"PLoS neglected tropical diseases","issn_l":"1935-2727","issn":["1935-2727","1935-2735"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-2","ki-jl-1","medline","norway-1","oarl","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLOS Neglected Tropical Diseases","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:7255612","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/7255612","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS Negl Trop Dis","raw_type":"Text"},{"id":"pmid:32413028","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/32413028","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS neglected tropical diseases","raw_type":"Journal Article"},{"id":"pmh:oai:RePEc:plo:pntd00:0008319","doi":null,"is_oa":false,"landing_page_url":"https://journals.plos.org/plosntds/article?id=10.1371/journal.pntd.0008319","pdf_url":null,"source":{"id":"https://openalex.org/S4306401271","display_name":"RePEc: Research Papers in Economics","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I77793887","host_organization_name":"Federal Reserve Bank of St. Louis","host_organization_lineage":["https://openalex.org/I77793887"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"article"},{"id":"pmh:oai:doaj.org/article:b82ebef1494f4efa9a932dcfe45f4de2","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/b82ebef1494f4efa9a932dcfe45f4de2","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"PLoS Neglected Tropical Diseases, Vol 14, Iss 5, p e0008319 (2020)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1371/journal.pntd.0008319","doi":"https://doi.org/10.1371/journal.pntd.0008319","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pntd.0008319","pdf_url":"https://journals.plos.org/plosntds/article/file?id=10.1371/journal.pntd.0008319&type=printable","source":{"id":"https://openalex.org/S46544255","display_name":"PLoS neglected tropical diseases","issn_l":"1935-2727","issn":["1935-2727","1935-2735"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-2","ki-jl-1","medline","norway-1","oarl","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLOS Neglected Tropical Diseases","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":1.0}],"study_designs":[{"id":"https://openalex.org/study-designs/systematic-review","display_name":"Systematic Review"},{"id":"https://openalex.org/study-designs/meta-analysis","display_name":"Meta-Analysis"}],"awards":[{"id":"https://openalex.org/G3207356259","display_name":null,"funder_award_id":"2007\u20132013","funder_id":"https://openalex.org/F4320320300","funder_display_name":"European Commission"},{"id":"https://openalex.org/G3792452373","display_name":"Care Package for Treatment and Control of Visceral Leishmaniasis in East Africa","funder_award_id":"305178","funder_id":"https://openalex.org/F4320320300","funder_display_name":"European Commission"},{"id":"https://openalex.org/G393177772","display_name":null,"funder_award_id":"FP7 2007-2013","funder_id":"https://openalex.org/F4320320300","funder_display_name":"European Commission"},{"id":"https://openalex.org/G5702163051","display_name":null,"funder_award_id":"FP7/2007","funder_id":"https://openalex.org/F4320320300","funder_display_name":"European Commission"}],"funders":[{"id":"https://openalex.org/F4320320300","display_name":"European Commission","ror":"https://ror.org/00k4n6c32"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3025613645.pdf","grobid_xml":"https://content.openalex.org/works/W3025613645.grobid-xml"},"referenced_works_count":70,"referenced_works":["https://openalex.org/W165904758","https://openalex.org/W1827183518","https://openalex.org/W1895017226","https://openalex.org/W1899376107","https://openalex.org/W1932235771","https://openalex.org/W1983997723","https://openalex.org/W1988325671","https://openalex.org/W2002661216","https://openalex.org/W2008552260","https://openalex.org/W2022956687","https://openalex.org/W2025903791","https://openalex.org/W2033925475","https://openalex.org/W2038565126","https://openalex.org/W2038805557","https://openalex.org/W2039812524","https://openalex.org/W2046144222","https://openalex.org/W2051210731","https://openalex.org/W2052276776","https://openalex.org/W2064321677","https://openalex.org/W2069077979","https://openalex.org/W2069127472","https://openalex.org/W2072621511","https://openalex.org/W2075893576","https://openalex.org/W2076026695","https://openalex.org/W2079451971","https://openalex.org/W2082977560","https://openalex.org/W2086258935","https://openalex.org/W2092226746","https://openalex.org/W2098042889","https://openalex.org/W2104010071","https://openalex.org/W2109642736","https://openalex.org/W2109788582","https://openalex.org/W2117860338","https://openalex.org/W2119605658","https://openalex.org/W2120156715","https://openalex.org/W2122814783","https://openalex.org/W2127044732","https://openalex.org/W2127260998","https://openalex.org/W2129359359","https://openalex.org/W2133957981","https://openalex.org/W2136086972","https://openalex.org/W2146292123","https://openalex.org/W2147221460","https://openalex.org/W2151324264","https://openalex.org/W2161186203","https://openalex.org/W2170801146","https://openalex.org/W2170956456","https://openalex.org/W2171925672","https://openalex.org/W2253132759","https://openalex.org/W2302266130","https://openalex.org/W2400138605","https://openalex.org/W2515900149","https://openalex.org/W2519666645","https://openalex.org/W2521970777","https://openalex.org/W2530242635","https://openalex.org/W2568800115","https://openalex.org/W2573226972","https://openalex.org/W2600940076","https://openalex.org/W2621978264","https://openalex.org/W2624865587","https://openalex.org/W2759540106","https://openalex.org/W2763819080","https://openalex.org/W2774336025","https://openalex.org/W2803896590","https://openalex.org/W3022903699","https://openalex.org/W4240133843","https://openalex.org/W4244322974","https://openalex.org/W4285719527","https://openalex.org/W4298845229","https://openalex.org/W4300885364"],"related_works":["https://openalex.org/W2008552260","https://openalex.org/W3010133705","https://openalex.org/W4398764439","https://openalex.org/W2345707099","https://openalex.org/W80142837","https://openalex.org/W7098872108","https://openalex.org/W1971296640","https://openalex.org/W2069219367","https://openalex.org/W7097027236","https://openalex.org/W3012864775"],"abstract_inverted_index":{"BACKGROUND:":[0],"Visceral":[1],"leishmaniasis":[2],"(VL)":[3],"is":[4,9,35],"a":[5,41,108],"vector-borne":[6],"disease":[7],"that":[8,301],"deadly":[10],"if":[11],"left":[12],"untreated.":[13],"Understanding":[14],"which":[15],"factors":[16,34,49,98,124,180,207,280,297],"have":[17],"prognostic":[18,33,48,123,179,203,279,296],"value":[19],"may":[20],"help":[21],"to":[22,46,90,193],"focus":[23],"clinical":[24,95,150],"management":[25],"and":[26,37,44,99,117,133,149,188,211,243,252,257,273],"reduce":[27],"case":[28],"fatality.":[29],"However,":[30],"information":[31],"about":[32],"scattered":[36],"conflicting.":[38],"We":[39,68,127,161],"conducted":[40],"systematic":[42,167],"review":[43,61],"meta-analysis":[45,194],"identify":[47],"for":[50,129],"mortality":[51,100],"among":[52],"VL":[53,77,105,171,308],"patients":[54,78,172],"in":[55,65,72,80,131,137,146,156,165,183,287,298],"East":[56,81],"Africa.":[57],"METHODOLOGY/PRINCIPAL":[58],"FINDINGS:":[59],"The":[60,205],"protocol":[62],"was":[63],"registered":[64],"PROSPERO":[66],"(CRD42016043112).":[67],"included":[69,162],"studies":[70,88,130,148,164,187,300],"published":[71],"English":[73],"after":[74],"1970":[75],"describing":[76,169],"treated":[79],"African":[82],"health":[83,285],"facilities.":[84],"To":[85,140],"be":[86,282,292],"included,":[87],"had":[89],"report":[91],"on":[92],"associations":[93],"between":[94,255],"or":[96,103,121,185],"laboratory":[97],"during":[101,104],"admission":[102],"treatment,":[106],"with":[107,215,260],"minimal":[109],"study":[110],"size":[111],"of":[112,119,144,173,267,307],"ten":[113],"patients.":[114,309],"Conference":[115],"abstracts":[116],"evaluations":[118],"genetic":[120],"immunological":[122],"were":[125,181,191,208,262],"excluded.":[126],"searched":[128],"MEDLINE":[132],"four":[134],"other":[135],"databases":[136],"December":[138],"2018.":[139],"assess":[141],"the":[142,154,166,305],"risk":[143],"bias":[145],"observational":[147],"trials,":[151],"we":[152],"used":[153],"Quality":[155],"Prognostic":[157],"Studies":[158],"(QUIPS)":[159],"tool.":[160],"48":[163],"review,":[168],"150,072":[170],"whom":[174],"7,847":[175],"(5.2%)":[176],"died.":[177],"Twelve":[178],"evaluated":[182],"five":[184],"more":[186],"these":[189],"results":[190],"submitted":[192],"producing":[195],"one":[196,256],"pooled":[197],"crude":[198],"odds":[199],"ratio":[200],"(OR)":[201],"per":[202],"factor.":[204],"following":[206],"strongly":[209],"(OR>3)":[210],"significantly":[212,251],"(P-value<0.05)":[213],"associated":[214,259],"mortality:":[216],"jaundice":[217],"(OR":[218,222,226,232,236,240,247,254],"=":[219,223,227,233,237,241,248],"8.27),":[220],"HIV":[221],"4.60),":[224],"tuberculosis":[225],"4.06),":[228],"age":[229,270],">45":[230],"years":[231],"3.69),":[234],"oedema":[235],"3.52),":[238],"bleeding":[239],"3.37),":[242],"haemoglobin":[244],"\u22646.5":[245],"g/dl":[246],"3.26).":[249],"Factors":[250],"moderately":[253],"three)":[258],"death":[261],"severe":[263],"malnutrition,":[264],"long":[265],"duration":[266],"illness,":[268],"young":[269],"(<5":[271],"years),":[272],"large":[274],"spleen":[275],"size.":[276],"CONCLUSIONS/SIGNIFICANCE:":[277],"These":[278],"can":[281],"identified":[283],"by":[284],"professionals":[286],"resource-constrained":[288],"settings.":[289],"They":[290],"should":[291],"considered":[293],"as":[294],"\"core\"":[295],"future":[299],"aim":[302],"at":[303],"improving":[304],"prognosis":[306]},"counts_by_year":[{"year":2026,"cited_by_count":8},{"year":2025,"cited_by_count":6},{"year":2024,"cited_by_count":12},{"year":2023,"cited_by_count":5},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":1}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2020-05-21T00:00:00"}