{"id":"https://openalex.org/W3025323312","doi":null,"title":"Phosphorylation of alpha4 integrin by PKA is required for endothelial cell alignment induced by shear stress","display_name":"Phosphorylation of alpha4 integrin by PKA is required for endothelial cell alignment induced by shear stress","publication_year":2007,"publication_date":"2007-10-16","ids":{"openalex":"https://openalex.org/W3025323312","mag":"3025323312"},"language":"en","primary_location":{"id":"mag:3025323312","doi":null,"is_oa":false,"landing_page_url":"https://www.cardioscience.ox.ac.uk/publications/883391","pdf_url":null,"source":{"id":"https://openalex.org/S116251202","display_name":"Circulation","issn_l":"0009-7322","issn":["0009-7322","1524-4539"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","doyens","jufo-3","ki-jl-3","medline","norway-2"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Circulation","raw_type":null},"volume":null,"type":"article","indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5003137587","display_name":"Lawrence E. Goldfinger","orcid":"https://orcid.org/0000-0003-0525-6008","observed_orcids":["https://orcid.org/0000-0003-0525-6008"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Lawrence E. Goldfinger","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-0525-6008","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029813850","display_name":"Ellie Tzima","orcid":"https://orcid.org/0000-0002-3437-0902","observed_orcids":["https://orcid.org/0000-0002-3437-0902"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ellie Tzima","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-3437-0902","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023251860","display_name":"Rebecca A. Stockton","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Rebecca Stockton","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030557604","display_name":"William Bill Kiosses","orcid":"https://orcid.org/0000-0003-1832-9050","observed_orcids":["https://orcid.org/0000-0003-1832-9050"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"William B. Kiosses","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-1832-9050","affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"Kazuhide Kimbara","orcid":"https://orcid.org/0000-0001-5390-3762","observed_orcids":["https://orcid.org/0000-0001-5390-3762"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Kazuhide Kimbara","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-5390-3762","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079542698","display_name":"Phan M. Nguyen","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Phan M. Nguyen","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068335042","display_name":"Shu Chien","orcid":"https://orcid.org/0000-0003-0332-285X","observed_orcids":["https://orcid.org/0000-0003-0332-285X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Shu Chien","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5032907445","display_name":"Mark H. Ginsberg","orcid":"https://orcid.org/0000-0002-5685-5417","observed_orcids":["https://orcid.org/0000-0002-5685-5417"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Mark H. Ginsberg","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-5685-5417","affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.45543006,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"116","issue":null,"first_page":"297","last_page":"297"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10831","display_name":"Cell Adhesion Molecules Research","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2723","display_name":"Immunology and Allergy"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10831","display_name":"Cell Adhesion Molecules Research","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2723","display_name":"Immunology and Allergy"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10379","display_name":"Cellular Mechanics and Interactions","score":0.0010999999940395355,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10169","display_name":"Protein Kinase Regulation and GTPase Signaling","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/integrin-alpha4","display_name":"CD49d","score":0.996999979019165},{"id":"https://openalex.org/keywords/protein-kinase-a","display_name":"protein kinase A","score":0.9639999866485596},{"id":"https://openalex.org/keywords/phosphorylation","display_name":"phosphorylation","score":0.9459999799728394},{"id":"https://openalex.org/keywords/endothelial-cell-alignment","display_name":"endothelial cell alignment","score":0.8569999933242798},{"id":"https://openalex.org/keywords/shear-stress","display_name":"shear stress","score":0.984000027179718},{"id":"https://openalex.org/keywords/integrin-signaling","display_name":"integrin signaling","score":0.5849999785423279},{"id":"https://openalex.org/keywords/endothelial-cells","display_name":"endothelial cells","score":0.45399999618530273}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7913870215415955},{"id":"https://openalex.org/C11960822","wikidata":"https://www.wikidata.org/wiki/Q242736","display_name":"Phosphorylation","level":2,"score":0.7671968936920166},{"id":"https://openalex.org/C195687474","wikidata":"https://www.wikidata.org/wiki/Q409715","display_name":"Integrin","level":3,"score":0.6308623552322388},{"id":"https://openalex.org/C21141959","wikidata":"https://www.wikidata.org/wiki/Q657936","display_name":"Shear stress","level":2,"score":0.5630748271942139},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.5040482878684998},{"id":"https://openalex.org/C123012128","wikidata":"https://www.wikidata.org/wiki/Q5376430","display_name":"Endothelial stem cell","level":3,"score":0.46896496415138245},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.40406256914138794},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.23873385787010193},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.19079133868217468},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.06679192185401917},{"id":"https://openalex.org/C57879066","wikidata":"https://www.wikidata.org/wiki/Q41217","display_name":"Mechanics","level":1,"score":0.06583511829376221},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.06111249327659607},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.0},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"mag:3025323312","doi":null,"is_oa":false,"landing_page_url":"https://www.cardioscience.ox.ac.uk/publications/883391","pdf_url":null,"source":{"id":"https://openalex.org/S116251202","display_name":"Circulation","issn_l":"0009-7322","issn":["0009-7322","1524-4539"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","doyens","jufo-3","ki-jl-3","medline","norway-2"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Circulation","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.4000000059604645}],"sustainable_development_goals_aurora":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2096388339","https://openalex.org/W3022983935","https://openalex.org/W2521899113","https://openalex.org/W1913083785","https://openalex.org/W2617295538","https://openalex.org/W2941269493","https://openalex.org/W2912185686","https://openalex.org/W2020371756","https://openalex.org/W1973010410","https://openalex.org/W147166547","https://openalex.org/W2594993789","https://openalex.org/W1989052759","https://openalex.org/W2189595722","https://openalex.org/W2963818070","https://openalex.org/W2160856472","https://openalex.org/W52413552","https://openalex.org/W2141779214","https://openalex.org/W2092228042","https://openalex.org/W2159302408","https://openalex.org/W3111189159"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-09-29T14:09:16.559479","created_date":"2025-10-10T00:00:00"}